In this conversation, Dr. Reza Ardalan sits down with Dr. Hugh Coyne, a London-based family medicine practitioner and the son of a pediatric dentist, who built Coyne Medical with his wife and clinical partner Dr. Lucy Coyne specifically to practice the kind of preventive medicine the NHS 10-minute appointment window does not allow. His training at Imperial College London and postgraduate work in obstetrics and gynecology, pediatric health, and sports medicine give him a panoramic view of the screening opportunities most dentists are sitting on without realizing it.

Dr. Coyne walks through the short blood panel he would build into every dental practice: HbA1c for diabetes risk that directly changes wound healing and periodontal outcomes, highly sensitive CRP for the kind of cardiovascular inflammation a UK Biobank study of over 400,000 people linked to a 61% higher risk of cardiovascular death, vitamin D with the K2 pairing that keeps calcium out of arterial walls, renal function, and a full blood count. From there, Dr. Coyne and Dr. Ardalan move into the oral microbiome shift from pathogen elimination to ecosystem restoration, the role of P. gingivalis in rheumatoid arthritis through citrullinated protein antibodies, and the cardiometabolic markers most patients never get tested for, including apolipoprotein B and lipoprotein(a). The third act covers GLP-1 medications, the Gila monster origin story, the medieval cautionary tale of Sancho the Fat, and the dental-chair implications most patients will never volunteer on a health history form.

In this Episode:

The short blood panel any dental practice can start with: HbA1c, highly sensitive CRP, vitamin D, renal function, and a full blood count
Why vitamin D supplementation without vitamin K2 may direct calcium into the wrong tissues, including arterial walls
How a UK Biobank study of more than 400,000 people linked elevated hs-CRP to a 61% higher risk of cardiovascular death in patients otherwise considered well
What the 87% of patients open to in-chair screening tells you about how to introduce blood testing in your practice without losing trust
The rule of halves for blood pressure, and why a 158 reading caught on a second visit can be profoundly consequential for a patient's long-term survival
How the oral microbiome model has shifted from pathogen elimination to ecosystem restoration, and what that changes about prevention
Why P. gingivalis turns up in rheumatoid arthritis tissue, and how oral pathogens correlate with colorectal, pancreatic, and esophageal cancers
The bachelor-party analogy for apolipoprotein B and lipoprotein(a), and why every dentist should know their own Lp(a) number
What every dental practice needs to know before sedating a patient on a GLP-1 medication

Dr. Hugh Coyne is a London-based GP and the co-founder, with his wife Dr. Lucy Hooper, of Coyne Medical, a family medicine practice focused on preventive care and the early detection of disease. Dr. Hugh Coyne trained at Imperial College London with postgraduate degrees in obstetrics and gynecology, pediatric health, and sports medicine, and is a featured speaker at the Wellness Dental Forum 2026. Find him on Instagram and TikTok at @drhughcoyne and the clinic at @coyne_medical.

Want to go deeper on the oral–systemic connection?

Dentistry & Whole-Body Health is a 3-part live CE series on reading the medical signals hiding in your patients' bloodwork — and knowing what to do with them.

Session 1: Hidden Signals · Saturday, November 7, 2026 The bloodwork your patients already have, read through a dentist's lens. HbA1c, hs-CRP, vitamin D, CBC — and when to monitor, pause, or refer.

Session 2: Cardiovascular Clues · Saturday, November 21, 2026 The lipid markers most panels skip (ApoB, Lp(a)) and the oral–heart connection behind them. Yes — this is the bachelor-party one.

Session 3: The New Weight Loss Era · Saturday, December 5, 2026 What GLP-1s are quietly doing to how your patients eat, metabolize, and heal — and the chairside adjustments that come with it.

All 3-hour sessions run 8 AM PT / 11 AM ET / 4 PM UK, with 30-day recording access if you can't make it live.

9 AGD-PACE-approved CE credits across the series. Nothing here asks you to become a doctor — it gives you the medical layer that's already shaping your outcomes.