This episode is brought to you by Cozy Earth, Fatty15, and Birch Living.

Cardiovascular disease still ranks as the leading cause of death for both men and women. Surprisingly, half of those affected show no symptoms before an event. Low levels of nitric oxide—a molecule that promotes vasodilation and smooth blood flow—could be primarily responsible. By recognizing the signs of deficiency, we can raise our levels and lower our risk.

Today on The Dhru Purohit Show, Dhru sits down for round two with Dr. Nathan Bryan to discuss why nitric oxide is the holy grail of molecules for long-term health. Dr. Bryan shares the four hallmarks of disease, the consequences of antacid overuse, and the correlation between lower nitric oxide and the risk of Alzheimer’s disease. Dr. Bryan also explains which lifestyle factors can hinder and boost nitric oxide production, how to test your levels, and symptoms that signal a deficiency.

Dr. Nathan Bryan is a renowned biomedical researcher known for his groundbreaking work on nitric oxide (NO) biology. Dr. Bryan's research has significantly advanced our understanding of NO's critical roles in cardiovascular health, immune function, and neurobiology. Beyond academia, he advocates for public health, translating his research into practical solutions for improving human health.

In this episode, Dhru and Dr. Bryan dive into (audio version / Apple Subscriber version):

Nitric oxide as the holy grail molecule (00:00:02 / 00:00:02)
Four hallmarks of disease (1:01 / 1:01)
Antacid medications: lack of research and the consequences of extended use (4:41 / 4:41)
Lower nitric oxide and the risk of Alzheimer’s (14:00 / 10:45)
Lifestyle habits that contribute to Alzheimer’s and biomarkers to check (17:15 /13:01)
What is nitric oxide and its core role in our bodies (27:00 / 23:39)
Lifestyle factors that hinder nitric oxide production (33:00 / 28:22)
Nitric oxide and high blood pressure (46:00 / 41:04)
Filtering water in your home and oral dysbiosis (51:00 / 46:30)
Navigating antacid medication usage and tapering off (1:11:00 / 1:06:50)
Testing nitric oxide level production (1:15:00 / 1:10:06)
The role of stress on our nitric oxide levels (1:29:00 / 1:24:53)
Foods that support production and supplementation (1:32:00 / 1:27:10)
Final thoughts: (1:44:00 / 1:39:40)

Also mentioned in this episode:

N1O1.com (get 10% off any of Dr. Bryan’s nitric oxide products with the code DHRU)
Bryan Therapeutics
EWG
Fygg Toothpaste

For more on Dr. Bryan, follow him on Instagram, Twitter, YouTube, and through his website,

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