← Diabetes Connections | Type 1 Diabetes
Diabetes Connections | Type 1 Diabetes
In the News.. Tzield approved for toddlers, generic Ozempic, Omnipod & Tandem updates, T1D Barbie honored... and more!
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Did you hear the pod drop? Did you know all the sounds used to make that song come from a sight? Change with the Omnipod 5 automated insulin delivery system. Pretty cool, huh? With Omnipod 5 pump site changes are simple. The pod lasts up to three days, 72 hours. And to change it, you just fill up the pod with insulin, place it on your body, tap a few buttons in the Omnipod 5 app and you're ready to go. There's no tubing to prime like with traditional insulin insulin pumps, and it's virtually pain free, so you never have to see or handle the insertion needle. Want to try Omnipod 5 for yourself? Request a free Omnipod 5 starter kit today by visiting omnipod.com diabetesconnections Terms and conditions apply. Eligibility may vary. Hello and welcome to another episode of Diabetes Connections. I am your host Stacey Sims and this is an in the News episode where we bring you the top diabetes stories and headlines happening now. A reminder, you can find the sources and the links and a transcript and more information for every story mentioned here. You can find all of that in the show notes over@diabetes-connections.com we are headed to New York tomorrow to White Plains just north of New York City for another Club 1921 event. We've got a little bit of a break after that, but then it's on to Chicago and Boston in June. Registration should be open for those two events. If not when you're listening to this, then imminently. But they are for healthcare providers and for patient leaders. What's a patient leader? It is a breakthrough T1D volunteer, somebody who works at Diabetes camp, a respectable influencer, somebody who is getting the message out to the greater community. And please, you know, tell your general practitioners and your pediatricians as well. We've had more and more of those folks at these events. And since this is about screening for Type one, it's really important that the you know that more of the general population and general healthcare professionals hear about it. And in fact, we've got a story coming up in the news about this as well. Really interesting time for screening. I don't usually talk about a lot of personal stuff during the in the news episodes, but I gotta tell you, Benny, my son who was diagnosed with type one at age two back in 2006, he went to New York City last week with a friend. The friend also just happens to have Type one. They went to see a concert, they went to Chinatown. They just wanted to have some fun and I was so nervous. But they did Great. Uh, I don't follow his dexcom anymore. Most of you know that. But he did ask me to look over his diabetes supplies before he left, which was so nice and exciting for me. I got to help him pack his diabetes bag. I know he did that for me for my stress level, you know, And I was nervous. Not because it's New York City. I grew up in that area. Not in the city, but just north. But, you know, just Travel alone with two 21 year olds. They're smart kids, but that age is not known for clear thinking and the best decision making. Let's just put it that way. But they did great. And that is why we are raising them to be independent and confident. Right? Right. Ugh. I still think one of my big regrets is telling that kid he could do anything with diabetes. Ugh. What was I thinking? All right, onto the news. Okay, our top story this week. The FDA approves TZ down to children ages 1 and older. TZLD is already approved for kids aged 8 and above. This was granted under a priority review process. Tzield is the only drug that is FDA approved to help delay the onset of type 1 diabetes. And this expansion includes people in stage 3 type 1 who can preserve endogenous insulin production for longer when they take Tzield. And for children in stage two, big write up in the Journal of Pediatrics about screening for Type 1, citing the 2025 ADA Standards of Care and diabetes. This opinion piece talks about how to engage the greater healthcare community and it says, in part, that we aim to encourage the development of strategies to emphasize the Importance of Type 1 Early detection and integrate screening into routine healthcare encounters. Pediatricians and other primary care clinicians are well positioned for a greater collaboration which could lead to timely intervention and improved outcomes. I was very excited to see this. Thank you to my pediatrician friends who sent it to me. I'm really excited to see if the greater healthcare community might actually start screening for type one. All right, more information about GLP1 drugs and people with type one. New study shows off label use did not lead to DKA or pancreatitis. In a large one year study, GLP1 use was actually associated with lower overall rates of hospitalization. Now, GLP1 drugs are not approved by the FDA for type 1, and about an eighth of the people in the study were using the older generation drugs like liraglutide. Lots more information to come on type 1 and GLP1s in upcoming studies. Health Canada has approved the first generic version of Ozempic about 3 million Canadian adults are currently taking GLP1 drugs. The Canadian patent for Ozempic has expired, paving the way for cheaper generic versions. Health Canada says it will be indicated to be used for the once weekly treatment of adult patients with type 2 diabetes to manage blood sugar levels. With three generics on the market, the price could drop to about $100 or less and Health Canada says it's currently reviewing eight other generic submissions by different companies and expects to make a decision in the next few weeks and months. Insulet has enrolled the first participant in a pivotal study for its fully closed loop aid system for type 2 diabetes. The participants are between 18 and 75 years of age, living with type 2 and using insulin. The company plans to submit to the FDA next year and hopefully launch the fully closed loop in 2028. There's no information here about any studies for fully closed loop for people with type 1 diabetes. I will follow up with Insulet and we will talk about that. Insulet has also initiated a voluntary recall of certain lots of Omnipod 5, detecting that some devices had a manufacturing defect that causes insulin leakage. The company has already notified the FDA and they say it's going to affect about 1.5% of Omnipod 5 pod units. Customers affected have already been notified, but please check the link and make sure to check your lot numbers. Insulet will give you a free product replacement Tandem Diabetes gets FDA clearance for its automated insulin delivery technology for use in pregnancy. The FDA cleared Control IQ for use in what they call pregnancy complicated by type 1 diabetes. Tandem now says T slim X2 and Mobi are the first and only commercially available aid systems cleared for use during pregnancy in the US And Tandem also issuing an urgent medical device correction for a software problem with the MOBI pump. The malfunction may cause insulin delivery to stop. We told you about this back in October. Tandem sent a letter then to customers notifying them the FDA has just now issued a Class 1 recall that is the most serious type. We just released a bonus episode on Friday, last Friday all about Tandem about tubeless MOBI and what else is in the pipeline. And you can listen to that wherever you are listening to this. It's the episode just before this one. Coming up, we've got new information about vitamin D preventing diabetes, predicting who will develop Type 1, and the T1D Barbie is still making news. That's coming up right after this. Right back to our conversation. But first, Diabetes Connections is brought to you by Dexcom. One of the coolest parts of A Dexcom CGM system is is how seamlessly it fits into our lives. Dexcom G7 can connect directly to an Apple Watch. With Dexcom direct to Apple Watch, you now have freedom and flexibility to go on a run, leave your phone in the car while running errands, or leave your phone on the charger while you're in another room. Or, let's be honest, when Benny has no idea where he left his phone, all while still getting the most accurate glucose readings in real time right on your wrist. It's also waterproof, comfortable to wear, and now comes in a 15 day version for adults. Benny is independent and active so this level of freedom matters for me. It's one more reason why I trust this technology. If you value real life usability, give Dexcom G7 a look back to the news now and switching CGMs did not make a measurable difference for adults. Using MiniMed's pump system, researchers found that CGM metrics for patients who switched from Guardian 4 to Instinct, that's the Abbott sensor, were able to maintain a time and range of greater than 75%. Now I am including this because all the headlines I saw on this seem to indicate that it didn't matter what CGM you used with an aid system. But when you look closer, the study is only looking at the two that work with Minimid. Still significant, but not exactly what the headline was. Promising vitamin D supplementation may help delay or prevent disease progression in people with prediabetes, in people who have specific variants in their vitamin D receptor gene. This was found after a second look at a large study where researchers found vitamin D didn't really make a difference. A second look with people who had a specific gene variation had much better results, they say. Now more specific research is needed to see what else is going on here with risk reduction. Sensonics has announced the first European launch of its Eversense 365 CGM. Eversense is the world's first 365 day CGM system. It also holds clearance as an integrated system. It can work with compatible medical devices. Right now it is integrated with the SQL MedTech Twist system. The company says it made Eversense 365 available to the first patients in Sweden already and will bring it to Germany, Spain and Italy in the coming weeks. A machine learning model can improve genetic prediction of type 1 by as much as 10%. There's already a risk score that has been widely tested and can be used to predict newborns who are at high risk of developing type 1 diabetes. These researchers built on that using a machine learning model. It was a big study. 20,000 people with type 1, 800,000 people without type 1. Mattel caused a big splash last summer when they released the first Barbie doll with type 1 diabetes in partnership with Breakthrough TE. Now the effort has won a gold Halo award for best cause product initiative. The Halo awards recognize the most outstanding corporate social impact efforts over the past year. Press release says Barbie worked closely with breakthrough T1D and type 1 diabetes community members to accurately reflect the medical equipment those with this condition may utilize. And the doll's look all the way down to the dress pattern. Of course, the color blue and the circle print on the dress are a nod to the global symbols that recognize diabetes awareness. I really thought that this Barbie would be a one and done that they would put it on the market as a very limited release. And I don't know if it was because the demand was so good or because this was the plan all along, but I'm thrilled that you can still purchase the Barbie. I don't know if you remember, but last summer, a lot of people, a lot of not so great people snapped it up and then tried to resell it on ebay for hundreds of dollars. But I just checked, you can buy it at Target online for $11. And I really hope Mattel keeps making it. And all of you adults with type one who have snapped it up, a couple of you have told me you feel a little funny about it. You know what? You deserve it. Get yourself a Barbie doll. Okay, that's it for in the news. If you like it, please share it. I mean, really share it. Do me a favor. Send this to somebody in the diabetes community. Send this to your doctor. Post it on Facebook. Share it with somebody that you think might benefit from the information that's here. I really appreciate it. And we're still growing. We're going on 11 years of this podcast, but we're still finding new people. So thank you for all of your help in that effort. Thank you to my editor, John Bukenis, from Audio Editing Solutions, and thank you so much for listening. I'm Stacey Sims. I'll see you back here soon. Until then, be kind to yourself. Diabetes Connections is a production of Stacey Sims Media. All rights reserved. All wrongs avenged. From the very beginning, they mean everything to you. And that means you do anything for them, especially if they're at risk. So when it comes to type 1 diabetes, screen it like you mean it. Even if just one person in your family has type one, you are up to 15 times more likely to get it too. Screen it like you mean it, because one blood test could help you spot type 1 long before you need insulin. Talk to your doctor about how to screen for type 1 diabetes, because the more you know, the more you can do. So don't wait. Visit screenfortype1.com to learn more. Again, that's screenfortype1.com.