Details

Ever wonder why sugar pills can kill pain, or why reading a side effect list actually causes those symptoms? In this mind-bending episode, McKyler takes Daniel on a deep dive into the placebo and nocebo effects—where belief literally rewires your brain’s chemistry. From Benjamin Franklin debunking “animal magnetism” in 1784 to modern patients improving on pills they know are fake, we explore the wild history and cutting-edge neuroscience behind medicine’s most mysterious phenomena.

Links

Open label placebo: can honestly prescribed placebos work?
Neurobiological Mechanisms of the Placebo Effect
Placebo effects on human μ-opioid activity during pain
Genetics and the Placebo Effect: the Placebome
Expectation and Dopamine Release: Mechanism of the Placebo Effect in Parkinson's Disease
Harnessing the power of placebos
The Story of the Placebo Effect

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