
Hosted by Dr. Terry Simpson · EN

Dr. Simpson Unfiltered MD: My Zepbound Journey (50 lbs Down), Food Noise, Side Effects & GLP-1 FactsIn the first episode of Dr. Simpson Unfiltered MD, weight loss surgeon Dr. Simpson and his producer April discuss his personal experience taking Zepbound for about a year and a half, including his fear of needles, a 50‑pound weight loss, minimal side effects, improved sleep, reduced “food noise,” decreased alcohol interest, refined taste for food and coffee, and lower measured stress. He shares his long history of weight fluctuations and diets, why he didn’t pursue bariatric surgery for himself, and explains GLP‑1 history and testing, including the Gila monster connection and long-standing clinical data. They address common concerns such as constipation/diarrhea, nausea, bone and muscle loss with weight loss, gallbladder disease vs pancreatitis risk, “Ozempic face,” thyroid cancer fears, and cautions about compounded GLP‑1s, emphasizing seeing an obesity medicine specialist and registered dietitian. This is a public episode. If you'd like to discuss this with other subscribers or get access to bonus episodes, visit www.drsimpson.com/subscribe

Food engineering isn’t all bad - this is from my other podcast - FORK U. If you don’t subscribe to it, here is from our latest episode. I hope you enjoy it. This is a public episode. If you'd like to discuss this with other subscribers or get access to bonus episodes, visit www.drsimpson.com/subscribe

A cruise ship outbreak. A newly sequenced Andes hantavirus strain. Social media panic. In this episode of The Unfiltered MD, Dr. Terry Simpson explains what the latest hantavirus sequencing actually shows — and what it does not.Why do some viruses mutate constantly while others remain remarkably stable? What is the “rule of six” in measles? Why do influenza and COVID boosters need updating while measles vaccines continue working decade after decade? And how do tiny molecular changes in viral surface proteins determine whether a virus can unlock a human cell?Dr. Simpson walks through the biology of viral mutations, receptor binding, purifying selection, zoonotic spillover, and why the shrinking world makes future pandemics inevitable — even if this hantavirus outbreak probably is not the next one.This is not panic.This is preparedness. This is a public episode. If you'd like to discuss this with other subscribers or get access to bonus episodes, visit www.drsimpson.com/subscribe

Cancer isn’t “suddenly exploding”—and it didn’t start with vaccines. The data shows a decades-long trend, a pandemic backlog of delayed diagnoses, and something far more important: we’re actually getting better at treating cancer. From targeted therapies to early mRNA breakthroughs, survival is improving—even in diseases that used to be a death sentence. This episode breaks down the myth of “turbo cancer,” the real drivers behind rising diagnoses, and why fear-based narratives are getting in the way of real care. This is a public episode. If you'd like to discuss this with other subscribers or get access to bonus episodes, visit www.drsimpson.com/subscribe

The internet says GLP-1 drugs are stealing your muscle. That “up to 40% lean mass loss” is supposed to scare you. But here’s the problem: it’s not new, it’s not unique, and it’s not what they say it is.In this episode, Dr. Terry Simpson breaks down what really happens to lean body mass during weight loss—whether it’s diet, surgery, or medications like semaglutide. He explains why glycogen and water get mislabeled as “muscle loss,” why severe protein deficiency is actually rare, and why most people naturally move more—and get stronger—after losing weight.Then we tackle bone: why some bone loss is a normal adaptation to carrying less weight, what actually causes osteoporosis, and why staying active matters far more than clinging to excess pounds out of fear.And yes—we take on the “gym bro” narrative that GLP-1s are dangerous unless you follow their program. (Spoiler: that’s not evidence, that’s marketing.)If you’ve heard the panic, this is the episode that puts it back into physiology. This is a public episode. If you'd like to discuss this with other subscribers or get access to bonus episodes, visit www.drsimpson.com/subscribe

If you are on a GLP-1 and talk about it, the carnivore crowd will attack your choices. There is a reason why. Carnivores have an ecosystem built around supplements, coaching, and etc. This is the story of how Carnivore started, and that it isn’t really a diet based in science - it is based in commerce This is a public episode. If you'd like to discuss this with other subscribers or get access to bonus episodes, visit www.drsimpson.com/subscribe

This is a free preview of a paid episode. To hear more, visit www.drsimpson.comMeasles cases surge as vaccination gaps widen. Colon cancer rises in younger adults. GLP-1 lawsuits reshape access. Deepfake doctors spread misinformation. This week, we connect the science, policy, and what you can actually do.

Colon cancer used to be considered a disease of older adults. Not anymore. After the deaths of actors like James Van Der Beek and Chadwick Boseman in their early 40s, many are asking why colorectal cancer is increasing in younger people. In this episode of Dr. Simpson Unfiltered, Dr. Terry Simpson explains the rise in early-onset colon cancer, the role of obesity, insulin resistance, IGF-1, inflammation, ultra-processed foods, microbiome disruption, childhood antibiotic exposure, and what the Mediterranean diet can do to lower risk. Most importantly, he discusses why screening at 45 — or earlier for high-risk individuals — remains the most powerful tool we have to prevent this disease. This is a public episode. If you'd like to discuss this with other subscribers or get access to bonus episodes, visit www.drsimpson.com/subscribe

This week on Dr. Simpson Unfiltered, I take a hard look at what medicine is — and what it isn’t. From the Peter Attia controversy and the responsibilities that come with medical training, to measles outbreaks threatening U.S. elimination status, pediatric vaccine failures, and why men develop heart disease years earlier than women, this episode is about duty, humility, and trust. Medicine isn’t built on personalities or shortcuts — it’s built on protecting patients, especially children, and making small, evidence-based steps forward that actually save lives. This is a public episode. If you'd like to discuss this with other subscribers or get access to bonus episodes, visit www.drsimpson.com/subscribe

This week on Dr. Simpson Unfiltered, we take on the uncomfortable truth of modern medicine: colorectal cancer is now the leading cancer killer in Americans under 50, heart disease still dominates despite powerful tools we underuse, and misinformation continues to cause real harm — from pregnancy fears to vaccine confusion. We also confront the new reality that millions now turn to AI for medical advice every day. Rather than panic, it’s time to redefine the doctor–patient relationship. This is medicine without dogma, without politics, and without paternalism — grounded in evidence, clinical experience, and the understanding that informed patients still need real doctors. This is a public episode. If you'd like to discuss this with other subscribers or get access to bonus episodes, visit www.drsimpson.com/subscribe