In this lecture from EHA2024, Prof Domenico Girelli from University of Verona, Italy, discusses the complex relationship between iron metabolism and infection.

As an essential element for physiology of all living organisms, iron is involved in many vital processes, including our immune responses to infections. Since the pathogens themselves also depend on iron to survive, the resulting host/pathogen “battle” for iron is one of the key determinants of outcomes of most infectious diseases.

Interestingly, this dependence of pathogens on iron may offer a much-needed solution for multidrug resistance (MDR) of microbes, which poses a significant and growing challenge for the global healthcare. Tune in, to hear about the novel “metallo-antibiotics” and other clinical developments based on accumulating data about role of iron in infections.

Guest: Prof Domenico Girelli

This episode is part of a series of lectures recorded at the EHA congress in Madrid in June 2024. This podcast containing accompanying slide content is available as a video on Spotify, YouTube, and EHA Campus. More lectures will be available in the future. Stay tuned!

For more information about a past or upcoming EHA Congress, visit https://ehaweb.org/congress/

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Iron and Infections: Back to the Future (EHA2024)