Dr. Babak Saboury, Chief Scientific and Innovation Officer and Physician Founder of United Theranostics, discusses the emergence of nuclear oncology as the fourth pillar of cancer care. United Theranostics is combining advanced molecular imaging and radiopharmaceutical therapies to identify a cancer cell's unique fingerprint and then delivering targeted radiation, reducing side effects by sparing healthy cells. Molecular imaging can serve as a unifying map for guiding a collaborative, multimodal approach to treating a range of cancers.

Babak explains, "I can just very quickly tell you that there are four pillars of treating cancer. Traditionally, when we approached cancer, we wanted to cut it out. That was surgical oncology. Whatever could not be cut out was treated by giving a medication. That was medical oncology. After a while, there was just a modality to the things that were difficult to cut out, but that was a localized hit from outside. That was the radiation oncology. And right now, we are at the beginning of a new horizon. You treat patients systemically, which means all the lesions everywhere. However, you are really there, a magical radiopharmaceutical that goes to find the cell and kills it by radiation. That's a nuclear oncology. So nuclear oncology is the fourth pillar of cancer care."

"So you can imagine that in the past we tried to attack cancer cells. We didn't know what shape they had, which proteins were expressed, or what their characteristics were. So we kind of went blindly and tried to attack them. Imagine that we have a way to find a fingerprint of those cells and go there first to find that fingerprint. And if the fingerprint exists, then go after those cells as a targeted attack. That is where molecular imaging and radiopharmaceutical therapy come into play. So molecular imaging profiles the cancer cells to see what their fingerprint is and whether a certain fingerprint exists. Radiopharmaceutical therapy uses this information to target just those cells and not other cells. And that is the principle of Theranostics, which is a combination of diagnostics and therapeutics, finding and then destroying in a very precise manner."

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