In this follow-up episode of Frame by Frame, host Chris St John reconnects with Dr. Ehsan Samei, a renowned medical physicist, to delve into how we truly measure the value of medical imaging. Moving beyond the conversation of dose alone, Dr. Samei shares how imaging quality and diagnostic effectiveness must be evaluated through multiple lenses—from resolution to task-specific metrics. This conversation breaks down why image quality is not one-size-fits-all and how the medical community is working toward standardization that benefits both patients and clinicians. Whether you're a radiologist, technologist, or healthcare decision-maker, this episode provides a deeper understanding of how we quantify imaging’s clinical impact.