From a fractured childhood in Weymouth to the creation of one of Britain’s most distinctive ethical brands, Mark Constantine’s life has been shaped by loss, sensitivity and an intense drive to make sense of the world through the senses.

In this episode of Full Disclosure, James O’Brien sits down with the co-founder and CEO of the British cosmetics retailer, LUSH. Expect a wide ranging and deeply personal conversation about abandonment, creativity and the long shadow of early experiences. Constantine traces his story from a family marked by absence and instability, through periods of homelessness and self doubt, to an unconventional career that fused science, intuition and care.

He reflects on grief, panic and the “entrepreneur’s wound”, and explains how synaesthesia shapes the way he understands people, memory and emotion. Smell, he suggests, can communicate what words cannot, reaching places in the brain where language falls short. Along the way, he speaks candidly about failure, fear of pride, and the mentors and partners whose kindness helped steady him.

They explore the unlikely origins of LUSH, the principles that guided its growth, and the tension between success and insecurity that has never fully gone away. Thoughtful, intimate and unexpectedly tender, this is a conversation about resilience, care and finding meaning through sensation rather than certainty.

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Mark Constantine: Homeless at 16 to Founding LUSH