Podcast Summary

Gloss Angeles: "Everything to Know about Jeuveau, Plus More of Your Questions Answered"

Hosts: Kirbie Johnson & Sara Tan
Guest: Vanessa Lee, RN (Founder of The Things We Do)
Air Date: November 21, 2025

Episode Overview

This episode dives deep into Jeuveau, a newer neuromodulator often compared to Botox, with special guest Vanessa Lee, RN. Vanessa, a sought-after aesthetics provider, discusses her clinical experience, what sets Jeuveau apart, and answers listener questions on injectables, skin treatments, and realistic beauty standards. The episode balances education with personal anecdotes and practical advice, making scientific info approachable for beauty enthusiasts and first-timers alike.

Key Discussion Points & Insights

1. What is Jeuveau? How Is It Different?

[02:09 – 05:01]

• Vanessa recalls first using Jeuveau in 2019, drawn by its Korean origins and innovative company leadership.
  • “I love everything in Korean when it comes to beauty." – Vanessa Lee [02:15]
  • She appreciates when a new, science-backed product enters the market.
• Target demographic: Younger users are attracted to Jeuveau for its accessibility and natural look.
  • “The things we do is really built around natural results and feeling good in your own skin.” – Vanessa Lee [03:10]
• Innovation:
  • Lighter, more natural feel compared to Botox or Dysport.
  • Faster onset (effects felt within 2-3 days) but more gradual, not abrupt ("not a punch in the face").
  • Effects last up to four months, possibly longer than Botox according to a University of Pennsylvania study published in JAMA.
    • “There was a study... and it showed that in comparison to Botox cosmetic, it lasted a little bit longer.” – Vanessa [03:50]

2. Real Experiences & Aesthetic Expectations

[05:01 – 08:39]

• Sara shares her first Jeuveau experience:
  • Had a unique "unicorn line" instead of 11s between her brows.
  • “I can still move my forehead... it looks really natural. And it started working in like two days!” – Sara Tan [06:01]
• Vanessa on natural vs. ‘frozen’ look:
  • Some clients want total stillness; others want to retain expression.
    • “I want to move. Yeah, I need to move.” – Vanessa Lee [08:19]

3. Jeuveau Research & Cosmetic vs Medical Toxins

[06:15 – 07:35]

• University of Pennsylvania study compared Botox, Dysport, Jeuveau, and Xeomin:
  • Jeuveau and Dysport onset in ~3 days
  • Jeuveau’s effects peak at 30 days, last longest (still effective at six months)
• Jeuveau was developed as a "beauty first" neurotoxin, not originally medical like other toxins.
  • “It was the first neurotoxin that is specifically made for beauty and cosmetic uses.” – Vanessa Lee [07:24]

4. Candidacy, Frequency, and Practicalities

[09:44 – 11:47]

• Vanessa explains patient assessment: checking for allergies, prior reactions, and making individualized plans.
• Personal schedules:
  • Vanessa personally does Jeuveau twice a year, but most patients do every four months for continuous effect.
  • “I do recommend to my patients... to keep up with it every four months.” – Vanessa Lee [10:22]
  • She notes lifestyle and career can affect injection timing (e.g., actors before filming, attorneys before trials).

5. Listener Q&A – Real World Beauty Tactics

"Hollywood 40 vs. Real-World 40"

[14:23 – 18:45]

• Vanessa dispels misconceptions about celebrity aging. Many celebrities are getting small, consistent treatments—not just luck or ‘clean living’.
  • “It’s consistent neuromodulators and consistent bio stimulator work. Not a ton of filler.” – Vanessa [18:04]
• The most natural results come from facial balancing and subtle enhancements.
  • Focus on holistic facial thirds, strengthening weaker areas for harmony.

Microneedling for Acne Scars

[21:03 – 22:46]

• Rolling acne scars respond best to microneedling (3-5 sessions, every 4-6 weeks, with 5-8% improvement per session).
• Ice pick and boxcar scars often require laser, not microneedling.
  • “Microneedling is fantastic when treating rolling acne scarring... but if you have the other two types, it’s really difficult.” – Vanessa Lee [21:23]

Sunspots and Melasma

[23:13 – 25:12]

• Picosure Pro Laser is Vanessa’s top pick for sunspots and melasma; if unavailable, alpha arbutin and niacinamide can help.
• Picosure Pro only targets damaged pigmented cells, sparing natural freckles and beauty marks.

Rosacea Care

[25:14 – 29:18]

• Vanessa, who has rosacea, recommends avoiding vitamin C and actives; focus instead on barrier-repairing ceramides and fatty acids.
• “Physiogel... it’s so accessible. I think it’s maybe like 17 bucks... for a huge bottle.” [27:56]
• Consider snow mushroom–based products (per Kirbie’s anecdote) for calming redness.

High Frequency Facial Wands

[29:30 – 32:32]

• Vanessa is obsessed with high frequency (HF) wands for acne and skin rejuvenation—she even developed her own during the 2020 lockdown.
• Warns against cheap/unknown brands due to potential malfunctions or safety risks (“They were electrocuting us. They were exploding.” – Vanessa [32:15])

Skincare for Bearded Men

[32:44 – 33:34]

• Cleanse and moisturize all the way under the beard, not just the visible skin.
  • “So much irritation is... skin underneath the beard not being cleansed properly and then also not having protection.” – Vanessa Lee [32:54]

Notable Quotes & Moments

• “If you’re not living and aging, you’re dying. But also, like, want to look a little spruced up from time to time.” – Kirbie Johnson [01:25]
• “There are seasons where I need to have that [expression] show up. My kids need to know Mama means business.” – Vanessa Lee [10:19]
• “We’re the generation where we have unlocked treatments in beauty that generations before us never had access to.” – Vanessa Lee [16:46]
• “Baby gut. Be so serious right now because I’ve been doing treatments for them for a long time. And it’s a lot of treatments, but it’s tasteful little treatments here and there.” – Vanessa Lee [18:04]
• “Microneedling is one of those thread treatments; Sculptra, hyper-dilute Sculptra, hyper-dilute Radiesse—all these things... strengthen the scaffolding of your tissues.” – Vanessa Lee [20:27]

Timestamps for Key Segments

• [02:09] – Vanessa’s Jeuveau experience, clinical differences
• [05:01] – Sara’s “unicorn line” and first Jeuveau injection
• [06:15] – Peer-reviewed research on Jeuveau vs. competitors
• [09:44] – Assessment and candidacy for treatment
• [10:19] – How often to get Jeuveau
• [14:23] – Listener Q&A: Celebrity procedures, "Hollywood vs. real-world aging"
• [21:03] – Microneedling for acne scars
• [23:13] – Sunspot and melasma solutions
• [25:14] – Rosacea at-home treatments and product recs
• [29:30] – High frequency wands: usage, risks, Vanessa's recommendations
• [32:44] – Bearded skin care tips for men

Overall Tone

The episode is warm and conversational with heavy dollops of practical skincare advice, clinical insight, and supportive takes on aging and self-image. Both hosts and Vanessa Lee blend compassion, expertise, and humor, ensuring listeners of all levels feel encouraged and informed, not intimidated.

Guest Info

• Vanessa Lee, RN: Founder of The Things We Do (LA & Hawaii), find her on Instagram @vanessalee.rn and @thethingswedo.

This episode is a treasure trove of honest advice on injectables, skin procedures, and debunking celebrity beauty myths—perfect for anyone curious about cosmetic treatments, regardless of where they are in their beauty journey.