Good Guys Podcast

Episode: Good Friends with Andrew Santino

Hosts: Josh Peck & Ben Soffer
Guest: Andrew Santino
Date: March 30, 2026

Episode Overview

This episode features comedian and actor Andrew Santino joining hosts Josh Peck and Ben Soffer for a hilarious, meandering, and candid conversation. The trio dives into everything from parental worries and aging, nightstand chaos, and microdosing, to their favorite reality TV shows, personal boundaries with addiction, tattoos, family dynamics, and even fantasy spouse-picking. Throughout, quick-witted banter, self-deprecation, and authentic vulnerability keep the tone both light and meaningful.

Key Discussion Points & Insights

The Art of (Not) Texting Back & Parental Worry

• Texting etiquettes: Andrew reveals he has different expectations based on the person he’s texting.
  • For best friends, like Bobby Lee, he’s lenient — "I give them a little bit more grace." (01:11)
  • But for parents, he panics if they don’t respond quickly: "If it's my mom or my dad panic, they don't text back within an hour. I'm freaking out because they're retired. What are you doing?" (01:37)
• Transition into the anxiety that accompanies aging parents; mutual commiseration about parental health and the absurdities of sleep apnea machines and nightstand clutter.

Comedy & Ego: Andrew’s Onstage Mishap

• Vegas incident: Andrew describes accidentally hitting himself in the face with the mic onstage, bleeding during his comedy set:
  • “The mic is stuck … and I’m like laughing it off at the crowd and I’m like, am I bleeding? And the guy in the front goes, yeah. And it’s dripping into my beard.” (07:00)
  • Led to an existential reflection on how performers sometimes let one blunder overshadow a whole great show.

Microdosing, Mushrooms, and Mental Health

• Microdosing routine: Andrew shares how he regularly microdoses mushrooms, primarily for depression and anxiety.
  • “I'm a big mushroom... I microdose mushrooms intermittently. So I take them in the morning, have a cup of coffee… It's more, it's less psychoactive…” (07:55)
• Advocates for doing “whatever makes you feel good”: “I'm not against people taking pills ... do whatever makes you feel good.” (08:41)
• Recreational stories: Shares anecdotes about accidentally chipping his tooth while high on mushrooms during a New Orleans bachelor party. A prime example of the show’s blend of humor and vulnerability.

Dream Celebrity Spouses

• The guys playfully debate: if they weren’t with their wives, which celebrity would be their spouse?
  • Andrew’s wife: Tom Hardy — “The things he would be able to do to her that I couldn't do… he's such a sultry looking person.” (21:35)
  • Ben: Vince Vaughn over John Mayer, because “I think Vince Vaughn could give her a beautiful life. John Mayer, I think he'd cheat on her.” (22:57)
  • Josh: JFK Jr., but with the lifestyle of a “middling NFL quarterback” – “the perfect...maybe just JFK Jr.” (25:35)
• Playful discussion of their wives’ “types.”

Addiction, Recovery, and Setting Boundaries

• Deep segment on addiction, centering around Bobby Lee’s relapses and Andrew’s boundary setting as a friend.
  • Santino: “I've dealt with it two times. One time was terrible. One time was very, very, very bad.” (30:02)
  • “You can't really batten down the hatches for that. You just gotta deal with it when it comes…” (30:18)
  • Talks about starting the Bad Friends podcast with Bobby after his recovery, highlighting how supportive friendships and tough love can go hand-in-hand.
• Josh commends Andrew: “I give you a lot of credit for being like...you knew that you couldn’t love him into getting better.” (33:27)

Accents & American Sexiness

• Discussion of regional U.S. accents and which are considered the “sexiest.”
  • Survey says Southern drawl is #1, but Santino argues for British as “the sexiest American accent is British!” (42:47)
  • Deconstruction of Southern, Boston, and Canadian accents—with Santino’s improv flair.
  • “The sweet Southern draw, yeah … but the deeper Southern draws, that's not sexy and sultry.” (37:44)

Reality TV & The Death of “Wacky Goofies”

• Preference for British competition shows (Great British Baking Show, Great Pottery Throw Down) over American fame-driven reality TV.
  • “American television competition turns into ‘how do I become famous when the show is over’...whereas in the British ones...‘how do I win because I want to be good at this?’” (45:51)
• Lamentation about the decline of comedic/goofy roles in TV and film.
  • “Nobody wants goof shit anymore. They want, you know, a ninth Avengers… I have no business over there.” (50:31)

Tattoos, Family, and the ‘What Are You Nuts?’ Round

• Santino critiques “knick-knack” (small, scattered) tattoos: “If you're gonna get a tattoo, get a tattoo. Don't be a knick-knacky tattoo.” (54:17)
• Josh and Ben joke about Jewish burial plots and tattooing numbers (Holocaust humor approached with dark irreverence).
• The “What Are You Nuts?” closing segment:
  • Ben: Own being a Disney adult; the hate is overrated—unless you go alone without kids (57:38)
  • Santino: “Speakerphone in public—what are you nuts?! ... Get headphones or put it up to your fucking head.” (59:14)
  • Josh: “Don’t close down the government. ... The real workers, the army ... maybe they shouldn’t miss a fucking check.” (58:22)

Notable Quotes & Memorable Moments

• “[When parents don’t text back] I’m freaking out because they’re retired. ... What are you doing? Napping? Or a doctor’s appointment?”
  — Andrew Santino (01:44)
• “I microdose mushrooms intermittently...for depression and anxiety. ... I didn’t want to get on pills. ... do whatever makes you feel good.”
  — Andrew Santino (08:41)
• "If love could cure people, there'd be so little addiction in the world."
  — Josh Peck (33:19)
• “The sexiest American accent is British.”
  — Andrew Santino (42:47)
• “Nobody wants goof shit anymore...We got to bring back the old. Where's new wacky goofy?”
  — Andrew Santino (51:38)
• "My biggest recent gripe right now is speakerphone in public—what are you nuts?"
  — Andrew Santino (59:14)

Timestamps for Major Segments

• Texting, Parents, and Aging: 00:56–03:46
• Nightstands & Sleep Apnea Machines: 03:46–04:42
• Phone Cases & Parenting Life: 05:16–05:37
• Andrew’s Mic Injury Story: 06:21–07:34
• Microdosing Mushrooms & Mental Health: 07:43–09:46, 22:32–22:45
• Addiction, Bobby Lee & Recovery: 29:08–34:34
• Regional Accents and Sexiness: 35:53–39:06, 42:47–43:38
• Reality TV vs. British Competitions: 44:44–46:59
• Actor Self-Doubt & Goofy Roles: 49:03–51:38
• Tattoos & Family Banter: 54:09–56:10
• What Are You Nuts? Segment: 56:48–61:37
• Plugs: 61:37–62:10

Tone and Language

This episode is characterized by fast-paced, sharp comedy, gentle ribbing, and personal honesty. The hosts and their guest slip effortlessly from heartfelt discussions about family and mental health into bits laced with irony, sarcasm, and friendly self-deprecation. At no point is the podcast sanitized; their humor can be dark, but it's delivered with warmth and authenticity.

Useful Links

• Andrew Santino: @cheetosantino
• Bad Friends Podcast: YouTube
• Whiskey Ginger Podcast: YouTube

For those who haven’t listened, this summary captures the mix of comedy, vulnerability, and the real-talk that makes "Good Guys" a unique, engaging listen—whether the hosts are riffing on the microanxieties of daily life, offering wisdom on boundaries, or just hunting for the sexiest American accent.