Andrew Huberman takes it. Peter Attia has been talking about it for years. Every serious longevity researcher has an opinion on it. And by age 40 to 60, your levels have already dropped by 50%.

NAD+ is one of the most important molecules in your body. It powers energy production in every cell, repairs DNA damage every single day, and activates the cellular pathways that regulate aging, inflammation, and metabolic function. The biology is not hype. But the way most people are taking it right now almost guarantees it is doing nothing. And Dr. G is done watching people waste their money on the wrong molecule in the wrong form at the wrong dose.

In this episode, you will learn:

• Why you cannot raise your cellular NAD+ levels by swallowing NAD+ directly, what happens to the molecule in your digestive tract, and the precursors that actually work

• The clinical research on NR vs NMN, which one has more published human trial data, which one the longevity research community is most excited about, and why sublingual delivery changes everything

• Why the serving sizes on most NAD+ labels are set to make the price look reasonable rather than match the research, and what a therapeutic dose actually looks like

Plus the specific brands Dr. G uses and trusts, and how to test your own intracellular NAD+ levels before and after to see if your stack is actually working.

Timestamps:

0:00 - NAD+ Drops 50% Between Ages 40 and 60 — Here's Why That Matters

1:37 - What NAD+ Actually Does in Every Cell of Your Body

2:15 - The Fatigue, DNA Damage & Accelerated Aging Tied to NAD+ Decline

3:39 - The Real Question: Is What You're Buying Actually Doing Anything?

4:09 - Why You Cannot Raise NAD+ by Swallowing NAD+ Directly

4:59 - The Three Precursors That Actually Work: Niacin, NR & NMN Explained

6:49 - NR vs. NMN: What the Latest 2026 Research Actually Says

7:34 - Why Most NAD+ Products on the Market Are Dangerously Underdosed

9:06 - Who Should Actually Be Taking NAD+ Precursors (And Who Can Wait)

10:14 - Dr. G's Clinical Recommendation: Sublingual NMN, Proper Dosing & Resveratrol Stacking 11:28 - How to Test Your NAD+ Levels Before and After Supplementing

11:42 - The Brands Dr. G Recommends

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