In this episode of The Histamine Well, host Joanne speaks with Amanda Bradshaw, co-founder of Mood Sense, to explore the critical role methylation plays in mood, mental health, and hormonal transitions like perimenopause. Joanne shares her clinical insights and surprising test results showing that some patients assumed to be under-methylators were actually over-methylating—changing the course of their treatment.

Amanda opens up about her personal health journey through perimenopause and how balancing her methylation significantly improved symptoms like mood swings and hot flushes. Together, they unpack how methylation imbalances can impact not just mental health, but also relationships, family dynamics, and even parenting—especially in neurodivergent households.

Listeners will also gain practical guidance on how the Mood Sense test works, and how diet, lifestyle, and targeted supplements can help restore balance and support emotional resilience.

Tired of treating symptoms instead of the root cause? 🎧

Join Joanne as she unpacks histamine intolerance, methylation, mold illness, and more—so you can finally feel calm, clear, and in control of your health.

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📘 New to this journey? Buy The Ultimate Bundle for Managing Histamine Intolerance—your step-by-step guide to manage your histamine intolerance effectively.

🎓 Practitioner or student? Enrolment for the Histamine & Methylation Online Group Coaching Course 2025 cohort is now open! Take advantage of Early Bird Offer available from 14 July to 3 August — join for just AUD 3,900 (pay in full) or opt for 3x monthly payments of AUD 1,366.

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18. Balancing Methylation: A Game-Changer for Mental Health, Perimenopause & Menopause

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