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What if the reason you still feel tired after optimizing hormones is not your hormones at all?

In this episode of Hormones, Metabolism, and You, Dr. Cassie Smith sits down with Dr. Terri DeNeui in Destin, Florida during an advanced hormone provider refresher to talk about the most common issue clinicians see after “optimizing hormones”: patients still feel tired, foggy, inflamed, or stuck. They break down why “normal” labs are not the same as optimal, why Free T3 matters, and how deficiencies in vitamin D, B12, and ferritin can block thyroid hormone function and keep symptoms alive. You will also hear how gut inflammation, H. pylori, and chronic acid blockers can sabotage hormone metabolism, why many “side effects” blamed on hormones are actually root-cause problems, and how to spot misinformation about estrogen and testosterone, especially for women.

About Dr. Terri DeNeui

Dr. Terri DeNeui, DNP, APRN, ACNP-BC, is a board-certified nurse practitioner, nationally recognized speaker, author, and the founder of EvexiPEL® and Evexia Medical. She holds advanced training in hormone replacement, preventive wellness, and functional medicine, and is known for her root-cause approach to optimizing hormones and whole-body health. Through her clinical work and provider education, Dr. DeNeui has helped transform the lives of thousands of patients and trained clinicians across the country. She is also the author of Hormone Havoc, a practical guide that clears up myths and misconceptions about hormones in women and men.

Key Topics Covered

Why patients can still feel “off” even when hormones look optimized
The thyroid lab most clinicians miss: Free T3
Why “normal” lab ranges often reflect a sick population, not optimal health
Vitamin D, B12, and ferritin: the hidden drivers behind fatigue, brain fog, and poor thyroid response
Ferritin and thyroid hormone: why low ferritin can block hormone function at the cellular level
Gut root causes behind low iron: heavy bleeding, hormone metabolism issues, H. pylori, and inflammation
Why chronic PPI use can worsen nutrient absorption and hormone conversion
Misconceptions about estrogen and cancer, and why metabolism and inflammation matter
Misconceptions about testosterone in women, plus why dosing and proper oversight change outcomes
Why hormone care works best when you treat the body as a system of systems

Resources & Links

🌐 Dr. Terri DeNeui LinkedIn: https://www.linkedin.com/in/terri-deneui/
📚 Book: Hormone Havoc: Dispelling the Myths and Misconceptions about Hormones in Women and Men – https://a.co/d/02qh7exW

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101: Fix Your Gut, Fix Your Hormones: The Missing Links When Thyroid + Hormones Aren’t Enough