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Late Eating and Obesity: A Meta-Analysis of Observational Studies (Nutr Rev, 2026)Este meta-análisis de estudios observacionales evidencia que comer tarde se asocia significativamente con un aumento del 17% en el riesgo de obesidad, efecto observado principalmente en adultos.

El estudio vincula este riesgo a mecanismos biológicos como la activación nocturna del gen BMAL1 que favorece la síntesis de lípidos y a la interferencia con la oxidación de grasas durante el ayuno nocturno.

Asimismo, se reporta que la ingesta tardía altera hormonas reguladoras del apetito, elevando la grelina y disminuyendo la leptina, lo que promueve un mayor consumo calórico total y dificulta el manejo del peso.