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This week on Inside EMS, Chris Cebollero takes on one of the most anxiety-inducing topics in paramedic education: alpha and beta receptors. Sparked by a question from paramedic student April McKenzie, a.k.a., “April Anonymous,” this episode strips away rote memorization and replaces it with something far more useful in the field — understanding the why behind the medicine.

There’s no fluff here; no cheesy memory tricks that fall apart under stress. Just physiology, practical mental models and a challenge to start practicing medicine with intention. If pharmacology has ever felt random, this episode connects the dots in a way that finally clicks.

Quotable takeaways

“Every medication you give in EMS is doing one of two things: It's either pushing the gas pedal or it's releasing the brake — that's it. If you don't understand which one you're doing, you're guessing, even if the protocol says you're right.”
“We really have to become the ultimate detective of the body.”
“Every patient is somewhere between gas and brake at all times. Those systems are constantly working, they're not off. It's just a dimmer switch. Every medication pushes one system or pulls the other system back into play.”

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