Mo Elshenawy helped put driverless cars on San Francisco streets as President and CTO of Cruise.

Now CTO of Hims & Hers, he joins Kyriakos to explain why rebuilding healthcare is harder.

They discuss closed-loop healthcare, clinical guidelines as code, when AI should remain silent, and whether AI will replace doctors.

Mo’s argument: models commoditize. Data and workflow compound.

At 25:13, Mo introduces Hims & Hers’ new AI weight loss companion.

CHAPTERS

(00:00) The Chessboard That Started It All

(02:22) AI Changed the Cost of Building

(04:17) Healthcare Is Harder Than Self-Driving

(06:13) Twice the Cost. 3.7 Fewer Years.

(09:17) Conviction Before Driverless Worked

(13:47) The Lunch That Changed His Career

(15:25) Healthcare Is Actually Sick Care

(18:03) Write Your Own Onboarding Plan

(19:43) AI Without a Platform Is Demoware

(23:06) Why OpenAI Can’t Close the Loop

(25:13) Hims’ AI Weight Loss Announcement

(28:42) Silence Is a Feature

(31:53) Clinical Guidelines as Code

(33:32) Most AI Benchmarks Are Theater

(36:12) Models Commoditize. Workflow Compounds.

(38:46) AI Will Not Replace Doctors

(44:37) AI Makes Bad Engineers Worse

(48:15) Healthcare Is Still Blockbuster

(52:00) Is Hims Getting Into Peptides?

(54:06) Concierge Care in Everyone’s Pocket

(58:46) AI Destroys the Excuse Not to Build