
Hosted by Nathalie Niddam · EN

📍 Good news! My original Instagram is back! Please follow my original account at https://www.instagram.com/nathalieniddam/ and also my backup account at https://www.instagram.com/longevitywithnat/.Today, I’m joined by Dan Pardi, a pioneering researcher who has dedicated years to understanding sleep, performance, and—the real focus of today’s conversation—the science of human energy. Dan unpacks how modern life is quietly draining our brain’s battery, and why brain energy, not just the march of time, could be the hidden driver of longevity.We dive into why short “exercise snacks” can outperform marathon workouts for keeping your brain sharp, how chronic stress and relentless screen time undermine cognitive performance, and the surprising reasons creatine is fast becoming a game-changer for brain health, not just muscle building.Visit qualialife.com/nathalie and use code NATHALIE at checkout to save 15%.Episode Timestamps:Welcome and podcast introduction ... 00:00:00Exercise snacks and their impact on cognitive performance ... 00:07:29How modern stress and technology deplete brain energy ... 00:12:12Environmental influences on sleep and energy ... 00:13:35Redefining aging as an energy management issue ... 00:18:41Muscle function, healthspan, and holistic longevity ... 00:21:53Why the brain demands so much energy ... 00:25:30Brain energy, cognitive decline, and examples like Alzheimer’s ... 00:29:07Creatine’s history in sports and its cellular mechanism ... 00:35:38Creatine’s cognitive benefits and how it reaches the brain ... 00:49:20Sleep, adenosine, and energy maintenance ... 00:54:39Creatine safety, kidney health, and gender differences ... 00:57:22Bloating, body composition, and dosing myths ... 01:05:30Why innovate creatine supplements and formulation upgrades ... 01:11:57Micronization, magnesium, sodium, and absorption ... 01:13:00Product testing and user experience ... 01:17:31Future of brain energy science in longevity ... 01:22:45Closing resources and medical disclaimer ... 01:28:47Our Amazing Sponsors:Quantum Upgrade – A 24/7 quantum energy streaming service designed to support energy, focus, sleep, recovery, and a more balanced nervous system, backed by placebo-controlled research showing measurable improvements in stress-related brain activity and heart rate variability. Try it free for 15 days with no credit card required at quantumupgrade.io/NAT and use code NAT15. MitoQ Hormonal Metabolic Control – A targeted formula designed to support women through the hormonal and metabolic shifts of perimenopause and menopause, featuring S-Equol for healthy estrogen signaling, B. breve to support the gut-hormone connection, and chromium to help maintain healthy blood sugar balance. Head to MitoQ.com/nat and use code NAT10 to try it for yourself.Nature's Marvels Bioregulators by Profound Health - Natural bioregulators designed to support your body's own cellular communication and healthy aging, with targeted formulas for everything from brain and immune health to sleep and vitality. Visit profound-health.com and use code NAT15 for 15% off your first order.Nat's Links:YouTube ChannelJoin My Membership CommunitySign up for My NewsletterOriginal InstagramBackup InstagramDr. Bill Lawrence Episode

📍 Good news! My original Instagram is back! Please follow my original account at https://www.instagram.com/nathalieniddam/ and also my backup account at https://www.instagram.com/longevitywithnat/.Today, I’m joined by Dr. Elisa Port, a trailblazing breast cancer surgeon and passionate advocate for women’s health. And the author of The Breast Advice In our conversation, Dr. Port traces her evolution from general surgery into breast surgery, sharing how the deeply collaborative decision-making with patients became her life’s calling. She gives an inside look at the optimism she found in this field—where advances in treatment have dramatically improved survival, offering hope and empowerment to countless women.Episode Timestamps:Welcome and show introduction ... 00:00:00Path to breast surgery and collaborative care ... 00:05:45Breast cancer, survival rates, and longevity factors ... 00:08:57Impact of weight and lifestyle on recurrence risk ... 00:10:45Dangers of information overload and misinformation ... 00:13:38Evaluating new screening tests and lacking validation ... 00:16:17Dense breast tissue and adjunctive screening ... 00:19:20Galleri blood test and research gaps ... 00:22:08Top lifestyle risk factors: weight and alcohol ... 00:23:32Self-awareness and moderation with food and alcohol ... 00:27:45GLP-1 medications and modern weight challenges ... 00:33:40Compounding health issues from obesity ... 00:37:37Long-term effects and benefits of weight loss drugs ... 00:40:09Hormone replacement, risk, and individualized care ... 00:45:34AI’s impact on breast imaging and detection ... 00:56:29Physical and mental recovery after treatment ... 01:00:31Future hopes: Cures and compliance ... 01:04:53Summary of optimal breast health strategies ... 01:06:27Our Amazing Sponsors:Wolverine by LVLUP Health – A peptide-based formula designed to support recovery, tissue repair, and musculoskeletal health, helping your body bounce back from workouts and everyday wear and tear. Head to lvluphealth.com and use code NAT for 15% off your order.MitoBlue by Wizard Sciences – A longevity-focused formula that combines pharmaceutical-grade methylene blue with NMN, PQQ, fisetin, and apigenin to support healthy mitochondria, cellular renewal, and healthy aging. Learn more at wizardsciences.com and use code NAT15 for 15% off.Vita Zero-Age Exosomes by Vitali Skincare — a regenerative “stacking” formula with exosomes, GHK-Cu, niacinamide, and glutathione designed to support your skin at a cellular level rather than just the surface; go to www.vitaliskincare.com/?ref=Nat20 and use code NAT20 for 20% off.Nat's Links:YouTube ChannelJoin My Membership CommunitySign up for My NewsletterOriginal InstagramBackup InstagramDr. Bill Lawrence Episode

📍 Good news! My original Instagram is back! Please follow my original account at https://www.instagram.com/nathalieniddam/ and also my backup account at https://www.instagram.com/longevitywithnat/.Today, I’m joined by Dr. Jill Crista, a pioneering voice in environmental medicine and a relentless detective when it comes to chronic, mysterious illness. In our conversation, Dr. Crista reveals how she uncovered the hidden world of mold and mycotoxins—not just as respiratory irritants, but as stealthy drivers of fatigue, brain fog, hormone disruption, and accelerated aging. She shares her early experiences working with “non-responders” in Lyme disease, and how uncovering toxic mold exposures transformed her entire understanding of whole-body health.Visit https://alighthealthformulas.com/nathalieniddam and code NATHALIENIDDAMEpisode Timestamps:Podcast intro and host background ... 00:00:00Peptides, bioregulators, and expert busting myths ... 00:02:10Foundations of hydration and health ... 00:03:55Mold as a multi-system problem, not just respiratory ... 00:06:12Clinical questionnaires for mold and Lyme ... 00:12:02Why mold illness is misunderstood ... 00:13:29Mycotoxins vs. visible mold, and detection tips ... 00:14:17Detox reactions and mold warning signs ... 00:22:46Remediation challenges: “dead” mold ... 00:28:35Different responses to mold exposure ... 00:29:43Protective nutrition and the microbiome ... 00:31:19Modern buildings and mold risks ... 00:33:35Break the Mold: the 5-step approach ... 00:35:23Pitfalls: skipping avoidance and early antifungals ... 00:35:38Bioflavonoids and alternative binders ... 00:37:24Aloe as a safe binder option ... 00:41:27Mold recovery “crashes” and toxicity ... 00:42:58Managing exposure when you can’t remediate ... 00:45:19Long COVID and its overlap with mold ... 00:50:43Essential oils and neuroinflammation support ... 01:04:08Mold, accelerated aging, and healthspan ... 01:07:03When to suspect mold in longevity “non-responders” ... 01:09:44Key questions, testing, and early action steps ... 01:10:23Hope, healing, and the importance of optimism ... 01:16:31Our Amazing Sponsors:Bioregulators & Peptides Summit by DrTalks – Cut through the confusion around peptides and bioregulators with free expert-led sessions covering healthy aging, metabolism, recovery, fasting, and the latest science in a practical, easy-to-understand way. Register for free today at https://drtalks.com/summits/NAT.Electrolyze by BEAM Minerals - Electrolyze is a plant-based fulvic mineral formula that delivers a full spectrum of highly bioavailable trace minerals and electrolytes to support hydration, nutrient delivery, and cellular energy. Head to beamminerals.com/NAT20, use code NAT20, and get 20% off your first order.Mitopure Gummies by Timeline – Supports healthier cellular energy, muscle strength, recovery, and healthy aging with clinically proven Urolithin A—without artificial sweeteners, colors, flavors, or unnecessary fillers. Head to timeline.com/nat20 to get Mitopure starting at just $99 and save an additional 20% on your order.Nat's Links:YouTube ChannelJoin My Membership CommunitySign up for My NewsletterOriginal InstagramBackup InstagramDr. Bill Lawrence Episode

📍 Good news! My original Instagram is back! Please follow my original account at https://www.instagram.com/nathalieniddam/ and also my backup account at https://www.instagram.com/longevitywithnat/.Today, I’m joined by Dr. Bill Lawrence, a leading researcher in longevity and pioneer in clinical studies on peptide bioregulators. Over the past eight years, Dr. Lawrence has dedicated himself to asking the big questions in longevity science: Do these interventions really work, and which strategies actually move the needle when it comes to living longer, healthier lives?Where to find Bioregulators: Visit Profound Health and use code NAT15 for 15% off your first order.Previous Episodes:#394 How Bioregulator Peptides HALVE Mortality: Telomere Reversal, Organs REGENERATED & the 8-Year Experiment With Dr. Bill Lawrence#256: Dr. Bill Lawrence: Bioregulator Peptides, New Insights on Aging, DNA Repair Mechanisms & the Impact of Stress on Telomere LengthDr Bill Lawrence: Reversing Aging PART 2 Bioregulator Peptides Effect on DNA Methylation Clinical TrialEpisode Timestamps:Welcome and podcast introduction ... 00:00:00Bioregulators: sourcing and beginner guidance ... 00:03:37Defining hope, hype, and science in longevity ... 00:09:02Framework for evidence-based interventions ... 00:11:08Lifespan, healthspan, and longevity distinctions ... 00:19:31Animal studies vs. human longevity research ... 00:27:51Recognizing hype and influencer marketing ... 00:33:33Experimental therapies: gene editing & reprogramming ... 00:36:06GLP-1 drugs and healthspan evidence ... 00:41:03Proven criteria for legitimate longevity interventions ... 00:46:03Mortality risk reduction: sleep, lifestyle, and relationships ... 00:47:47Evidence ladder: from mice to human studies ... 00:53:13Peptide bioregulators: research history and mechanisms ... 01:01:19Organ regeneration and biological age reversal ... 01:21:20Epigenetic age, pace of aging, and case studies ... 01:34:00Our Amazing Sponsors:C.A.R.E. Mitochondrial Moisturizer Young Goose – An upgraded cellular skincare formula featuring Methylene Blue and Liposomal Creatine to support mitochondrial function, skin barrier health, and resilient, hydrated skin. Click HERE and use code NAT10 to save on C.A.R.E. Mitochondrial Moisturizer.NEW Magnesium Breakthrough Advanced 10 by BIOptimizers – A magnesium formula featuring 10 bioavailable forms of magnesium, plus active vitamin B6 and ionic trace minerals, designed to support sleep, recovery, stress, and metabolic health. Visit bioptimizers.com/bionat and use code BIONAT for 15% off, exclusive bonuses, and free shipping on select orders.Grass-Fed Whey by Puori - A third-party tested, grass-fed whey protein delivering 21g of protein per serving, with every batch tested for over 200 contaminants and results available via a QR code for complete transparency. Head to puori.com/NAT20 and use code NAT20 to get 32% off your first subscription order, plus a free premium shaker bottle.Nat's Links:YouTube ChannelJoin My Membership CommunitySign up for My NewsletterOriginal InstagramBackup InstagramDr. Bill Lawrence Episode

Today, I’m mixing things up with a special episode that takes you on a tour through some of the most compelling moments from the past quarter. Rather than a typical interview or solo deep dive, I’ve curated standout clips from episodes that lit a fire under important longevity conversations and resonated deeply with both me and the team.We’ll cover the markers that could signal your body’s terrain is welcoming to cancer, practical strategies for calming an agitated nervous system when mast cell issues show up (especially with age), and the truths about Lyme disease that most people—maybe even your doctor—completely miss. You’ll also hear expert advice on EMF protection that separates real solutions from the noise, and gather insights on long COVID that go way beyond the headlines and arm you with things you can actually do.Whether you’re here to pick up new tips for optimizing your health or just looking for that nudge of inspiration to dig deeper into your own wellness journey, this longevity mix has something for you.Follow my NEW Instagram @longevitywithnat and my existing Instagram @nathalieniddam (that’s back…for now).Episodes In This Recap:#436: Is Your Body’s Terrain Hospitable For Cancer? Affordable Lab Tests, Metabolic Flexibility, and Emotional Foundations With Dr. Nasha Winters#434: Are You Aging Like Someone Else? (How To Find Your PERSONAL Path to Healthspan) With Sandra Kaufmann#450: Lyme, Bartonella & Babesia EXPOSED: Hidden Vectors, Lost Lives, and the Battle for Early Detection With Nicole Bell#435: FINALLY! A Guide To What YOU Can Do About EMF Exposure To Better Protect Your Body With R Blank#447: Gut AWAKENING: The Silent Epidemic of Spike Protein, Long Covid, and Accelerated Aging | Dr. Robin RoseEpisode Timestamps:Welcome and podcast introduction ... 00:00:00Quarterly highlight episode explained ... 00:00:31How to share feedback and engage with the show ... 00:01:04Key episode topics previewed: cancer, mast cells, Lyme, EMFs, long COVID ... 00:01:58Dr. Nasha Winters: cancer risks and early lab markers ... 00:02:49Why CBC, CMP, and the “trifecta” matter for longevity ... 00:08:56Terrain over tumor: tracking health before imaging reveals problems ... 00:14:01Dr. Sandy Kaufmann: mast cells in aging and solutions ... 00:14:18How hormone changes expose mast cell vulnerability ... 00:24:01Nicole Bell: Lyme misdiagnosis and chronic illness links ... 00:29:23Why Lyme often goes undetected and the need for better testing ... 00:33:05New diagnostics and empowering patient action ... 00:41:27R. Blank: what non-native EMFs are and why they matter ... 00:44:37EMF exposure, health risks, and practical home strategies ... 00:55:22Dr. Robin Rose: what drives long COVID and what to do ... 00:59:10Gut health, spike protein, and actionable recovery steps ... 01:06:19Conclusion and safety reminder ... 01:11:55Our Amazing Sponsors:Vita Zero-Age Exosomes by Vitali Skincare — a regenerative “stacking” formula with exosomes, GHK-Cu, niacinamide, and glutathione designed to support your skin at a cellular level rather than just the surface; go to www.vitaliskincare.com/?ref=Nat20 and use code NAT20 for 20% off.MitoBlue by Wizard Sciences – A longevity-focused formula that combines pharmaceutical-grade methylene blue with NMN, PQQ, fisetin, and apigenin to support healthy mitochondria, cellular renewal, and healthy aging. Learn more at wizardsciences.com and use code NAT15 for 15% off.Wolverine by LVLUP Health – A peptide-based formula designed to support recovery, tissue repair, and musculoskeletal health, helping your body bounce back from workouts and everyday wear and tear. Head to lvluphealth.com and use code NAT for 15% off your order.Nat's Links:YouTube ChannelJoin My Membership CommunitySign up for My NewsletterOriginal InstagramBackup InstagramDr. Bill Lawrence Episode

📍 Good news! My original Instagram is back! Please follow my original account at https://www.instagram.com/nathalieniddam/ and also my backup account at https://www.instagram.com/longevitywithnat/.For years, we've been told to prioritize our muscles, our hormones, and our heart health—but what about our brains? Today's conversation explores why women are at a greater risk for Dementia and Alzheimer's, why brain changes begin decades before symptoms appear, and why so many warning signs are dismissed as "just stress" or "just menopause."I'm joined by Emma Heming Willis, co-founder of Make Time Wellness and Dr. Nicole Beurkens, Make Time Wellness Scientific Advisor, for an incredibly honest discussion that blends cutting-edge neuroscience with deeply personal experience. We discuss cognitive resilience, how to care for your brain NOW, hormone health, and the simple habits that can help protect your brain for years to come.If you've ever experienced brain fog, become a caretaker for someone you love, or wondered what you can actually do to protect your cognitive health, this episode is one you won't want to miss. Visit https://maketimewellness.com/NAT and use code NAT for 20% off products. Episode Timestamps:Women's Brain Health Is Being Overlooked ... 00:00:00Why Women's Brain Health Has Been Ignored ... 00:09:13Why Alzheimer's Begins Decades Before Diagnosis ... 00:16:26Brain Fog vs. Dementia: Knowing The Difference ... 00:17:31Hormones, Menopause & The Brain ... 00:22:08Becoming A Caregiver Overnight ... 00:25:41The Hidden Health Risks Of Caregiving ... 00:26:19How To Tell Normal Brain Changes From Dementia ... 00:30:00Why Women Need More Self-Compassion During Menopause ... 00:34:00The Power Of Community & Social Connection ... 00:36:07What Every Woman Should Know About Brain Health Earlier In Life ... 00:39:33Grief, Anger & Caregiver Guilt ... 00:44:22How Dementia Changes An Entire Family ... 00:47:25Why Women Face A Higher Alzheimer's Risk ... 00:50:26The Caregiver Wake-Up Call ... 00:49:00Genetics vs. Lifestyle: Can You Lower Your Risk? ... 00:59:50The Biggest Modifiable Dementia Risk Factors ... 00:56:16Sleep, Blood Sugar & Brain Health ... 01:08:00Supplements That Support Cognitive Health ... 01:10:00Where To Learn More ... 01:24:32Our Amazing Sponsors:Countdown Insiders – A $21/month membership funding mitochondrial research, with exclusive education, expert conversations, member experiences, and partner perks. Longevity listeners get their first month free with code NATHALIE. Learn more at https://joincountdown.org/membership/ Blue Cannatine by Troscriptions – Precision-formulated troches designed to support sustained focus and mental clarity, helping you stay sharp through long workdays, recording sessions, travel, and everything in between. Visit troscriptions.com/NATPODCAST or use code NATPODCAST at checkout to save 10% off your first order.LongeFera by Regenerive - A precision-formulated ashwagandha supplement that isolates four key bioactive compounds to support a healthy stress response, cognitive function, balanced inflammation, and cellular longevity—without the fillers and inconsistent extracts found in many products. Head to regenerive.co and use code NAT25 for 25% off your order.Nat's Links:YouTube ChannelJoin My Membership CommunitySign up for My NewsletterInstagramDr. Bill Lawrence Episode

📍 Please don’t forget to follow my NEW Instagram account at https://www.instagram.com/longevitywithnat/My guest today is James LaValle R.Ph., C.C.N. M.T. DHM, DHPh, one of the pioneers in functional and metabolic medicine, and we're unpacking the silent process he calls metaflammation—the chronic, low-grade inflammation that can quietly drive everything from fatigue and insulin resistance to hormone imbalances and accelerated aging.Episode Timestamps:Introduction & Why "Normal" Labs Can Be Misleading ... 00:00:00Why Treating Symptoms Without Addressing the Cause Doesn't Work ... 00:10:53The Cascade From Metabolic Dysfunction to Chronic Disease ... 00:13:38Why Standard Blood Tests Often Miss Early Disease ... 00:17:08Hidden Blood Markers & Pattern Recognition in Lab Work ... 00:19:39Why We Normalize Feeling Bad ... 00:23:17Empowering Patients Instead of Accepting "Getting Older" ... 00:25:05Environmental Toxins, Mold, Heavy Metals & The Exposome ... 00:31:00Detoxification: What Actually Works? ... 00:35:00Finding a Practitioner Who Looks at the Whole Picture ... 00:36:53GLP-1 Medications: Benefits, Risks & Common Misconceptions ... 00:44:20Essential Amino Acids, Creatine & Preserving Lean Mass ... 00:58:24Titrating GLP-1s vs. "Microdosing" ... 00:60:11Wearables, Biomarkers & The Future of Health Tracking ... 01:26:52Rapid-Fire Questions: Most Underrated Biomarker, Sleep & Recovery ... 01:27:10Our Amazing Sponsors:MitoQ Hormonal Metabolic Control – A targeted formula designed to support women through the hormonal and metabolic shifts of perimenopause and menopause, featuring S-Equol for healthy estrogen signaling, B. breve to support the gut-hormone connection, and chromium to help maintain healthy blood sugar balance. Head to MitoQ.com/nat and use code NAT10 to try it for yourself.Nature's Marvels Bioregulators by Profound Health - Natural bioregulators designed to support your body's own cellular communication and healthy aging, with targeted formulas for everything from brain and immune health to sleep and vitality. Visit https://profound-health.com/?Aff=Longevity15 and use code NAT15 for 15% off your first order.C.A.R.E. Mitochondrial Moisturizer by Young Goose – An upgraded cellular skincare formula featuring Methylene Blue and Liposomal Creatine to support mitochondrial function, skin barrier health, and resilient, hydrated skin. Click HERE and use code NAT10 to save on C.A.R.E. Mitochondrial Moisturizer.Nat's Links:YouTube ChannelJoin My Membership CommunitySign up for My NewsletterInstagramDr. Bill Lawrence Episode

📍 Please don’t forget to follow my NEW Instagram account at https://www.instagram.com/longevitywithnat/Most people think that if they can just find the right mold test, they'll finally have their answer. But what if that's exactly what's keeping them stuck?In this episode, I'm joined once again by mold investigator and building health expert Jason Earle, and we challenge some of the biggest assumptions surrounding mold illness. We unpack why modern homes may be working against our health, why the building itself should be viewed as part of your wellness ecosystem, and why one test can never tell the whole story.If you've been dealing with unexplained symptoms, wondering whether your home could be part of the equation, or simply want to create a healthier environment for yourself and your family, this conversation will completely change the way you think about the place you call home.Visit https://www.gotmold.com/ and use the code Nat10.Dust test link: https://dusttest.gotmold.com/E-Book - https://www.gotmold.com/ebook-landing-page/Article he mentioned: https://www.gotmold.com/testing-for-mold-avoid-ermi/?srsltid=AfmBOor_h1U3x5pZnPnHZcC6V4ecKUSnXczMNBtybtaVQrSfkfIHfBPEEpisode Timestamps:Introduction: Why Most Mold Tests Miss the Real Problem ... 00:00:00Why Modern Homes Can Become Health Hazards ... 00:13:00How Modern Construction Created Health Problems ... 00:17:22The First Warning Signs Your Home May Be Making You Sick ... 00:21:30Mold, VOCs & Why New Homes Aren't Always Safer ... 00:24:48Construction Mistakes That Trap Moisture Inside Walls ... 00:25:37Why You Should Build a Relationship With Your Home ... 00:28:57The Dangerous Search for a Single "Perfect" Mold Test ... 00:29:54What a Proper Mold Assessment Actually Looks Like ... 00:30:35Why ERMI Can Create False Confidence or Unnecessary Panic ... 00:33:55Petri Dish Tests: Why Jason Calls Them Junk Science ... 00:35:31How Outdoor vs. Indoor Mold Should Really Be Compared ... 00:36:56The Problems With ERMI's Original Design ... 00:39:18Introducing AI-Powered Dust Testing & the Future of Mold Detection ... 00:44:00Air Testing vs. Dust Testing: When Each Matters ... 00:46:37Why Dust Creates a Historical Record of Your Home ... 00:48:42When Symptoms and Test Results Don't Agree ... 00:51:00The Nervous System's Role in Mold Illness ... 00:53:17Confirmation Bias in Mold Testing & Functional Medicine ... 00:57:32The Most Important Steps for Recovery ... 00:59:24Our Amazing Sponsors:MitoBlue by Wizard Sciences – A longevity-focused formula that combines pharmaceutical-grade methylene blue with NMN, PQQ, fisetin, and apigenin to support healthy mitochondria, cellular renewal, and healthy aging. Learn more HERE and use code NAT15 for 15% off.Mitopure Gummies by Timeline – Supports healthier cellular energy, muscle strength, recovery, and healthy aging with clinically proven Urolithin A—without artificial sweeteners, colors, flavors, or unnecessary fillers. Head to timeline.com/nat20 to get Mitopure starting at just $99 and save an additional 20% on your order.MassZymes by BIOptimizers - A full-spectrum digestive enzyme formula with 4x more protease than leading competitors to help maximize protein digestion and nutrient absorption. Visit bioptimizers.com/bionat and use code BIONAT for 15% off your order plus a free travel-size bottle of MassZymes while supplies last.Nat's Links:YouTube ChannelJoin My Membership CommunitySign up for My NewsletterInstagramDr. Bill Lawrence Episode

📍 Please don’t forget to follow my NEW Instagram account at https://www.instagram.com/longevitywithnat/For years we've talked about longevity as if the answer is hiding in the next supplement, biomarker, or miracle molecule. But what if we've been looking at aging through far too narrow a lens? Today's guest, Dr. Marios Kyriazis, has spent decades challenging that idea by exploring aging through medicine, complexity science, cybernetics, and even philosophy.We unpack what bioregulators actually are, why so much of the conversation around them has become overhyped, and how concepts like hormesis, adaptation, and even our relationship with technology may shape how we age. This is one of those conversations that starts with peptides and ends with a much bigger question: what does it really mean to build a longer, healthier life?Where to find Bioregulators: visit https://profound-health.com/?Aff=Longevity15 and use code NAT15 for 15% off your first orderEpisode Timestamps:Introduction to Dr. Marios Kyriazis & Rethinking Aging ... 00:00:00Why Humans Age Differently Than Animals ... 00:06:49The Role Of Consciousness, Stress & Positive Thinking ... 00:13:19What Peptide Bioregulators Actually Are ... 00:15:29Manufacturing, Quality Control & Why Source Matters ... 00:18:24Carnosine, Natural Extracts & The Origins Of Bioregulators ... 00:19:48Organ Extracts, Food & Ancient Healing Traditions ... 00:23:20Natural vs. Synthetic Bioregulators ... 00:26:19Personalized Medicine & Why One Size Doesn't Fit All ... 00:30:00Side Effects, Safety & Clinical Experience ... 00:37:01Professor Cavinson's Research: Why The West Remains Skeptical ... 00:38:32The Biggest Misconceptions About Bioregulators ... 00:44:22Cycling Bioregulators & The Principle Of Hormesis ... 00:47:47How Many Bioregulators Should You Take? ... 00:50:10Oxidative Stress, Free Radicals & Aging ... 00:51:45Do Bioregulators Reduce Oxidative Damage? ... 00:54:37Why Quality Manufacturing Is So Difficult ... 00:57:12Avoiding Routine As A Longevity Strategy ... 01:07:42Practical Longevity Advice For Midlife ... 01:11:07Our Amazing Sponsors:Blue Cannatine by Troscriptions – Precision-formulated troches designed to support sustained focus and mental clarity, helping you stay sharp through long workdays, recording sessions, travel, and everything in between. Visit troscriptions.com/NATPODCAST or use code NATPODCAST at checkout to save 10% off your first order.Quantum Upgrade – A 24/7 quantum energy streaming service designed to support energy, focus, sleep, recovery, and a more balanced nervous system, backed by placebo-controlled research showing measurable improvements in stress-related brain activity and heart rate variability. Try it free for 15 days with no credit card required at QuantumUpgrade.io and use code NAT15. Just Thrive 90-Day Probiotic – A spore-based probiotic that survives stomach acid to arrive 100% alive in your gut, supporting better digestion, nutrient absorption, immunity, and less bloating. Start your first 90-day subscription today and you'll get a FREE 90-day supply of Digestive Bitters (a $90 value) to help optimize digestion and support healthy appetite regulation. Click HERE to learn more.Nat's Links:YouTube ChannelJoin My Membership CommunitySign up for My NewsletterInstagramDr. Bill Lawrence Episode

📍 Please don’t forget to follow my NEW Instagram account at https://www.instagram.com/longevitywithnat/If you've been hearing everyone talk about exosomes but still aren't exactly sure what they are—or whether they're actually worth the hype—this episode is for you. Today I'm joined once again by Amitay Eshel and Anastasia Khodzhaeva from Young Goose to separate the science from the marketing and unpack what exosomes are really doing inside your skin.We explore why your skin may be the most honest reflection of your biological age, how mitochondrial health and cellular repair influence the way you age, and why not all exosome products are created equal. We also get into the future of longevity skincare, formulation science, and what consumers should actually be looking for before spending money on the latest trend.Special Young Goose Offer: Click HERE and use code NAT10 to save on Young Goose products!Links to previous episode:#381: Better Than Lasers: NAD+, Spermidine, and Methylene Blue for Youthful Skin | Amitay Eshel and Anastasia Khodzhaeva#209: How to Reverse The Aging Process Without Long Term Damage with Amitay Eshel#118: Our Skin is a Mirror: Why Skin Health is a Marker of Overall Health#71: How to Boost the Effects of Anti-Aging Skincare and Light TherapyEpisode Timestamps:Introduction & Returning Guests ... 00:00:00Why Skin May Be Your Most Honest Longevity Biomarker ... 00:08:52Gut Health, Mitochondria & What Your Skin Reveals ... 00:14:15Biological Age vs Chronological Age ... 00:19:08Performance, Longevity & Resilience: Three Ways to Think About Aging ... 00:21:34The Exosome Revolution: What Are Exosomes? ... 00:30:18Why Most Consumers Ask the Wrong Questions About Exosomes ... 00:34:08Platelet vs Stem Cell Exosomes Explained ... 00:38:03Why Formulation Matters More Than Marketing ... 00:43:51How Young Goose Built Their Exosome Formula ... 00:52:28Formulation Science vs The Next "Miracle Ingredient" ... 00:59:21Where Longevity Skincare Is Headed Next ... 01:08:48Final Thoughts & Young Goose Discount Code ... 01:14:06Our Amazing Sponsors:Manukora Honey – A delicious real-food source of prebiotics, Manukora's high-MGO Manuka honey helps support your gut microbiome, digestion, and immune health with just one teaspoon a day. Head to MANUKORA.com/NAT to save up to 31% plus receive $25 worth of free gifts with the Starter Kit.Electrolyze by BEAM Minerals - Electrolyze is a plant-based fulvic mineral formula that delivers a full spectrum of highly bioavailable trace minerals and electrolytes to support hydration, nutrient delivery, and cellular energy. Head to beamminerals.com/NAT20, use code NAT20, and get 20% off your first order.Grass-Fed Whey Protein by Puori - A third-party tested, grass-fed whey protein delivering 21g of protein per serving, with every batch tested for over 200 contaminants and results available via a QR code for complete transparency. Head to puori.com/nat and use code NAT20 to get 32% off your first subscription order, plus a free premium shaker bottle.Nat's Links:YouTube ChannelJoin My Membership CommunitySign up for My NewsletterInstagramDr. Bill Lawrence Episode