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Liana Byrne
As tariff threats loom, a UK based pharma giant is going big on the US Live from the uk this is the Marketplace Morning Report from the BBC World Service. I'm Liana Byrne. Good morning. So, drug maker AstraZeneca says it'll invest $50 billion in the United States by 2030, its biggest ever manufacturing investment in the country. The Anglo Swedish firm, which is headquartered in Cambridge, England, plans to build a major new site in Virginia. It's the latest in a big str of pharma bets on in the US with rivals like Roche and Sanofi also ramping up speed. And why now? Well, it comes as Donald Trump threatens steep tariffs on drug imports, a warning that's pushing companies to make more of their products stateside. It's a loss for the UK despite the British government announcing a $700 million fund to support pharma manufacturing. Mark Samuels is chief executive of Medicines uk, which represents British pharmaceutical firms. Hello.
Mark Samuels
Good morning.
Liana Byrne
So Mark, what do you think? Do you think this move is going to help AstraZeneca sidestep these tariffs?
Mark Samuels
Well, decisions of this scale are never made overnight, and AstraZeneca had evidently prioritised the US even before the Trump administration came into power. America accounts for almost half the company's revenue, so it was always going to be a significant investment location.
Liana Byrne
But for the UK that's probably not a good thing, is it?
Mark Samuels
Well, any loss of manufacturing, and this is a very large manufacturing investment, is unhelpful to the uk. You know, we're fantastic at doing research in the uk, but we need manufacturing to translate that research and development into growth into gdp. It's manufacturing products and services that provides the country with gdp. So it is disappointing to lose that. That said, the UK government has announced its life sciences sector plan and that includes a thriving to support British manufacturing.
Liana Byrne
What about for the US AstraZeneca is not the only pharma giant that has made this type of investment. Are we going to see a trend going forward?
Mark Samuels
Most of the big pharmaceutical companies make around half their profits in the U.S. so it's, it's no surprise that that's going to be a prime, if not the prime country to invest in.
Liana Byrne
Okay. Mark Samuels, chief executive of Madison's uk Thank you so much for joining us on Marketplace.
Mark Samuels
Thank you.
Liana Byrne
Now let's do the numbers. Foreign appetite for Indian government bonds is bouncing back. Investors poured in about $1.5 billion over the past month. It's all because some are betting the Reserve bank of India could cut interest rates again in August if inflation stays low and growth looks shaky. But in the uk, demand for bonds fell slightly as new figures reveal that government borrowing, that's the difference between what the government spends and what it raises in taxes, is at its highest since 2021. And tax rises later in the year. And China's indices hit fresh highs. Hong Kong's Hang Seng climbed to a multi year peak and Shanghai stocks hit an eight month high. All boosted by a new huge dam project in Tibet set to be the world's largest. The world's most famous cycle race is underway, the Tour de France. After a rest day in Montpellier, riders are hitting the road again for stage 16, finishing with a brutal climb up the legendary Mont Ventou. It's the first time in four years that the 6,000 foot mountain has featured in the Tour. But its mythic status keeps it packed with cyclists from around the globe. Thomas Butin is the chief executive of Rev du Velo, a bike shop based in Montpellier and has a branch right at the foot of Ventou. I asked him how significant the Tour is for his business.
Thomas Butin
It's a big event for Montpellier. It's a good opportunity for us. It's a good opportunity to organize events in Montpellier.
Liana Byrne
In Montventou, do you expect more customers? And how are you getting ready for that?
Thomas Butin
What we see is the impact is more important in Mont Ventoux than Montpellier, because Mont Ventou, as you know, is mythical. And a lot of people in the world want to climb Mont Ventou.
Liana Byrne
And what type of bike would you need to climb that big steep part of the Tour de France?
Thomas Butin
The question of the bike is interesting because now we can climb Montpentou with all kind of bike, road bikes. The most what people use because they want to do the same as the provider. But actually we have people who climb Mont Venture with gravel bikes. We have people climb Montvente with electric bikes.
Liana Byrne
So in terms of percentage of sales increases, what are you expecting from this Tour de France?
Thomas Butin
It's too early for us to know the impact on the sale of the bike. This year the rental part is increased about 50%. We organize bike tours, we are tour operators and we are official operators of Tour de France. And we sell bike tours on the Tour de France. And it's a really important part of our business. And we have a lot of people coming all over the world. We have Chinese, for example, people, and a lot of American clients, also Mexican, etc. Who come for ride the road of the Tour, for example, in Montbantou. This year we organize the climb of the Montbantou. During the day the provider will ride, we climb in the morning, we have access to the finish line with our clients and after they can see the tour during the lunch. And we enjoy all the week in Montventour because our shop is on kilometre zero of the climb and we have a good space just close to the road. We have a food truck behind the bike shop. We will have some big brands like Kinarello, Bryston, Continental, who will come and present their new product.
Liana Byrne
It's a big event for us, definitely. It sounds like it. How is the bike retail industry in general? We talk a lot with a lot of industries about rising costs. How are you finding things over the last couple of years?
Thomas Butin
As you know, during the COVID the industry grew up a lot. But after the COVID it was difficult because a lot of brand have so many stock and the price go up and go down. It was a little complicated, actually. The bike industry is a little chaotic. But we sell a lot of bike more than before the COVID But for the one who are beginner and with less experience, it's more difficult.
Liana Byrne
So. Matt Bhutan, chief executive of Rev Develop and I'm Liana Byrne with the Marketplace Morning report from the BBC World Service.
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Release Date: July 22, 2025
Host: Liana Byrne
Episode Title: Drugmaker AstraZeneca invests big in the U.S.
In a significant move signaling confidence in the U.S. market, British-Swedish pharmaceutical giant AstraZeneca announced a colossal investment of $50 billion in the United States by 2030. This marks the company's largest-ever manufacturing investment within the country. The plan includes the construction of a major new manufacturing facility in Virginia, underscoring AstraZeneca's commitment to expanding its footprint in the American market.
AstraZeneca's decision to ramp up its U.S. investments comes at a time when the company faces potential challenges from U.S. tariffs on drug imports. Liana Byrne reported:
“It comes as Donald Trump threatens steep tariffs on drug imports, a warning that's pushing companies to make more of their products stateside.” (01:21)
This strategic shift aims to mitigate the impact of these tariffs by increasing domestic production, thereby reducing reliance on imported drugs and navigating the evolving trade landscape.
Mark Samuels, Chief Executive of Medicines UK, provided his insights into AstraZeneca's move:
“AstraZeneca had evidently prioritised the US even before the Trump administration came into power. America accounts for almost half the company's revenue, so it was always going to be a significant investment location.” (02:05)
While the investment bolsters AstraZeneca's presence in the U.S., it poses challenges for the UK pharmaceutical sector. Samuels expressed concerns over the potential loss of manufacturing capabilities in the UK:
“Any loss of manufacturing, and this is a very large manufacturing investment, is unhelpful to the UK... it's disappointing to lose that.” (02:25)
Despite these setbacks, the UK government has introduced a $700 million fund to support the life sciences sector, aiming to reinforce British manufacturing and counterbalance such moves by major firms.
The trend of pharmaceutical companies increasing their investments in the U.S. is not limited to AstraZeneca. Samuels highlighted that:
“Most of the big pharmaceutical companies make around half their profits in the U.S. so it's no surprise that that's going to be a prime, if not the prime country to invest in.” (03:03)
This shift signifies a broader industry strategy to consolidate market presence where profitability is highest, ensuring sustained growth and stability.
Foreign investment in Indian government bonds has seen a resurgence, with investors pouring in approximately $1.5 billion over the past month. This influx is driven by speculation that the Reserve Bank of India may cut interest rates in August if inflation remains low and economic growth appears shaky.
Contrastingly, demand for UK government bonds has slightly declined. Recent figures indicate that government borrowing—the gap between government spending and tax revenue—has reached its highest level since 2021. Additionally, potential tax increases later in the year have contributed to the reduced attractiveness of UK bonds.
Chinese stock indices have reached new heights, with Hong Kong's Hang Seng climbing to a multi-year peak and Shanghai stocks hitting an eight-month high. This surge is largely attributed to the announcement of a massive dam project in Tibet, poised to become the world's largest, boosting investor confidence and market performance.
The prestigious Tour de France is currently underway, bringing significant attention and economic activity to the region. Thomas Butin, Chief Executive of Rev du Velo, a Montpellier-based bike shop located at the base of the legendary Mont Ventoux, shared insights into the event's impact:
“It's a big event for Montpellier. It's a good opportunity for us... the impact is more important in Mont Ventoux than Montpellier.” (04:55)
Butin highlighted the diverse clientele attracted by the Tour, including international tourists from China, the U.S., and Mexico, who visit to experience the challenging climbs firsthand. The shop caters to various biking preferences, offering road bikes, gravel bikes, and electric bikes suitable for conquering Mont Ventoux.
“We have people who climb Mont Ventoux with gravel bikes... electric bikes.” (05:16)
While it's early to quantify the exact sales increase, Butin noted a 50% growth in bike rentals this year. Rev du Velo also organizes official bike tours aligned with the Tour, further driving business and providing unique experiences for participants.
“We organize bike tours on the Tour de France... we have a good space just close to the road.” (05:36)
The bike industry has experienced significant growth, particularly during the COVID-19 pandemic. However, post-pandemic challenges include fluctuating inventory levels and price instability, making the market somewhat chaotic. Butin observed:
“The bike industry is a little chaotic. But we sell a lot of bikes more than before the COVID.” (07:14)
Despite the complexities, Rev du Velo continues to thrive by adapting to market demands and leveraging major events like the Tour de France to sustain and grow their business.
AstraZeneca's substantial investment in the United States underscores a pivotal shift in the pharmaceutical industry's focus towards the U.S. market, driven by both strategic financial considerations and external pressures such as potential tariffs. This development not only impacts the companies involved but also has broader implications for the UK economy and the global pharmaceutical landscape. Concurrently, economic indicators from India, the UK, and China present a mixed outlook, while local events like the Tour de France continue to stimulate regional economies and specific industries like bike retail.
Note: Timestamps in quotes refer to the points within the provided transcript. For access to the full episode, visit Marketplace Morning Report