What Do I Need to Know About Pulsed Field Ablation?

Guest: Christopher DeSimone,

Host: Anthony Kashou, M.D.

In this episode of “ECG Making Waves, hosted by Dr. Anthony Kashou with guest Dr. Christopher DeSimone, the focus is on understanding the evolution of ablation technology, particularly why the field has shifted toward pulsed field ablation. The conversation explores the key differences between traditional thermal ablation methods and pulsed field ablation, highlighting mechanisms, safety profiles, and clinical advantages. Additionally, it provides insight into what patients and clinicians can expect on the day of an ablation procedure, as well as important considerations for post-procedure follow-up and recovery.

Topics Discussed:

What is pulsed field ablation?
What are some of the differences between risks seen with thermal ablation vs. those seen with pulsed field ablation?
How does efficiency of the procedure or speed of the procedure change what you do for ablation?

Connect with Mayo Clinic's Cardiovascular Continuing Medical Education online at https://cveducation.mayo.edu or on Twitter @MayoClinicCV and @MayoCVservices.

LinkedIn: Mayo Clinic Cardiovascular Services

Cardiovascular Education App:
The Mayo Clinic Cardiovascular CME App is an innovative educational platform that features cardiology-focused continuing medical education wherever and whenever you need it. Use this app to access other free content and browse upcoming courses. Download it for free in Apple or Google stores today!

No CME credit offered for this episode.

Podcast episode transcript found here.

Recorded on: 28-January-2026