Annie Potts has starred in some iconic movies and TV shows - “Ghostbusters,” “Toy Story,” “Designing Women,” and “Young Sheldon” just to name a few. Annie talks with me about her latest role as Aunt Sarah the “lobsterwoman” on “Best Medicine” (new episodes air Tuesdays at 8pm ET on FOX and stream the next day on HULU); how she balanced motherhood amidst 22-episodes-a-season on “Designing Women”; her now-viral “Tonight Show” moment with Shelley Winters; and what convinced her to take the role of Bo Peep in “Toy Story” (hint: it wasn’t her agent who talked her into it!).

00:00 From Tomboy to Lobster Woman

01:35 Adapting Doc Martin for Best Medicine

03:49 The Weird Leap Into TV & Film

04:44 That Shelly Winters Tonight Show Moment

06:10 How Ghostbusters Really Happened

07:29 Working With Bill Murray & Improv Chaos

08:56 Feeling Lost in an Improv Room

09:44 Designing Women & Ensemble Magic

11:28 Being a Workaholic

12:48 Raising Kids While Filming 26 Episodes

15:13 Becoming Bo Peep in Toy Story

17:29 Taking Grandkids to Disneyland

21:27 Broadway Debut at 57

23:56 Learning the Trapeze at 62

24:57 The Near-Fatal Car Accident at 21

26:27 Roles That “Got Away”

27:41 Why She’ll Never Retire

29:16 The Las Vegas Memory With Joan Rivers

30:43 Craft Services & Raising Kids on Set

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Annie Potts is the Best Medicine