If tragedy plus time equals comedy, then it’s no surprise the four-year estrangement between my guest Mayan Lopez and her father, comedian George Lopez, yields sitcom gold in “Lopez Vs. Lopez” (new episodes Tuesdays at 8/7c on NBC and streaming on Peacock). As the show begins its second season, Mayan shares how she mines laughs from heavy subjects like infidelity, alcoholism, and race; how a TikTok video led her to network TV stardom, and how she blazed her own trail in the entertainment business through improv and sketch comedy.

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