On this week's Brands of the Week episode of On Brand with Donny Deutsch, Donny breaks down the brands winning and losing in today's cultural and political landscape — and what it all means for public perception, reputation, and influence.

This week's biggest brand stories include: Israel's deepening PR crisis as a new Gallup poll reveals a 31-point drop in support among older Democrats and growing losses across Republicans, Catholics, and evangelicals — and why the Netanyahu factor is accelerating the damage. Plus, Donald Trump signs an executive order expanding federal research into psychedelics like psilocybin and ibogaine — a surprising brand move that earns him a rare brand-up. Then, a potentially game-changing pancreatic cancer drug doubles survival time in clinical trials, offering hope for one of the deadliest cancers. Also covered: Trump's signature on U.S. currency draws a 59% disapproval rating, TMZ opens a Washington D.C. bureau to treat politicians like celebrities, American Eagle doubles down on Sydney Sweeney despite controversy, the FAA recruits gamers as air traffic controllers, Hardee's makes a Southeast comeback, and the Washington Commanders add a spear to their logo. Donny also weighs in on ancestry travel trends, the return of men's monograms, Baby Jessica's fall from grace 40 years later, and the science behind why rewatching Cheers and Golden Girls is actually good for your brain. Thursday's episode features a full interview with entrepreneur and former presidential candidate Andrew Yang on his plans for 2028.

Brands mentioned: Israel, Benjamin Netanyahu, Donald Trump, FDA, pancreatic cancer drug Elzovantinib, TMZ, American Eagle, Sydney Sweeney, Hardee's, Washington Commanders, Pittsburgh tech hub, Jill Biden, Heated Rivalry, Maryland state symbol, FAA, 23andMe, Ancestry travel, Andrew Yang

Learn more about your ad choices. Visit megaphone.fm/adchoices