In this episode of On the Edge of Breakthrough: Voices of Cancer Research, Dr. Monty Pal welcomes Dr. Tanya Dorff, professor in the Department of Medical Oncology & Therapeutics Research and section chief of the Genitourinary Disease Program at City of Hope. Together they dive into Dorff’s pioneering work in immunotherapy for prostate cancer - from the challenges of moving treatments from bench to bedside, to the importance of collaborative team-science, and the role of deep biological correlates in informing future studies. Beyond her clinical and research achievements, Dr. Dorff reflects on mentorship, work-life balance, and the importance of supporting diversity of thought in academic medicine. She shares how creative pursuits help her recharge and offers advice for aspiring oncologists to pursue their passions and embrace bold leaps at the edge of breakthrough. Tune in to discover how clinical innovation, collaboration, and a patient-centered approach are the secret sauce...