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What happens when a devastating diagnosis becomes the catalyst for a complete life transformation?

Meet Irene Pasternak, whose journey from an early Alzheimer's diagnosis to becoming a marathon runner reveals the extraordinary possibilities that emerge when we refuse to accept limitation. At 65, Irene received news that would stop most people in their tracks: test results showing an 86% chance of full dementia within three years. Instead of retreating, she embarked on a running journey that would transform both her brain health and her entire approach to living.

Irene shares how she discovered "tourist running" – an approach that combines exploration with exercise as she runs as far as possible in new directions before taking public transport home. This creative method helped her progress from barely managing a mile to completing half marathons in less than a year. Most remarkably, her brain scans now show amyloid plaque levels dropping from 76 to below 12 – under the clinical significance threshold – suggesting her treatment and lifestyle changes have dramatically altered her prognosis.

Beyond running, Irene reveals her work as a Feldenkrais practitioner helping people overcome movement limitations, and how she leads summer backpacking trips with llamas for people with Parkinson's disease. Her approach to movement as playful exploration rather than rigid exercise offers valuable insights for runners of any age. The conversation weaves through topics of neuroplasticity, resilience, and finding purpose after diagnosis – including how she now treasures time with her young granddaughter, creating memories she once feared would be impossible.

Whether you're a runner seeking fresh perspective, someone facing health challenges, or simply in need of inspiration, Irene's story reminds us that sometimes our greatest adventures begin precisely when we think our stories are ending. Subscribe now and share this episode with someone who might need to hear that their diagnosis doesn't have to be their destiny.

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S3 Ep 11 From Alzheimer's to Marathon Runner: A Journey of Resilience with Irene Pasternack

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