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In this episode of POP Profiles, part of the Power Over Parkinson’s series, we sit down with Dr. Jamie Eberling, SVP and Head of Imaging at the Michael J. Fox Foundation, to discuss one of the biggest challenges in Parkinson’s research: developing an alpha-synuclein tracer. Alpha-synuclein is the protein that accumulates in the brains of people with Parkinson’s disease, but scientists still cannot reliably image it in living patients. Dr. Eberling explains why finding this tracer is so complex—and why solving it could be a major breakthrough. We explore how an alpha-synuclein tracer could transform diagnosis, accelerate therapeutic development, improve clinical trials, track disease progression, and ultimately move the field closer to disease-modifying treatments and a cure.

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Parkinson’s Research: Unlocking Alpha-Synuclein Tracers