Rheumatoid Arthritis explained, including pathophysiology and typical signs and symptoms (extra articular too!). We also look at rheumatoid arthritis diagnosis (with rheumatoid factor / Anti CCP) and medications such as DMARDs

PDFs available here: https://rhesusmedicine.com/pages/rheumatology

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Timestamps:
0:00 What is Rheumatoid Arthritis?
0:23 Rheumatoid Arthritis Pathophysiology
2:58 Rheumatoid Arthritis Symptoms
5:16 Rheumatoid Arthritis Diagnosis
7:02 Rheumatoid Arthritis Treatment

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References

MSD Manual Professional Edition (2025) Rheumatoid arthritis. MSD Manual Professional Edition. Available at: https://www.msdmanuals.com/professional/musculoskeletal-and-connective-tissue-disorders/joint-disorders/rheumatoid-arthritis
BMJ Best Practice (2025) Rheumatoid arthritis – Symptoms, diagnosis and treatment. BMJ Best Practice. Available at: https://bestpractice.bmj.com/topics/en-gb/105
Firestein GS, Budd RC, Gabriel SE, McInnes IB, O’Dell JR. Kelly and Firestein’s Textbook of Rheumatology. 11th ed. Elsevier; 2021.
McInnes IB, Schett G. The pathogenesis of rheumatoid arthritis. N Engl J Med. 2011;365:2205–2219.
Smolen JS, Aletaha D, McInnes IB. Rheumatoid arthritis. Lancet. 2016;388:2023–2038.
Abbas AK, Lichtman AH, Pillai S. Cellular and Molecular Immunology. 10th ed. Elsevier; 2021.
Kumar V, Abbas AK, Aster JC. Robbins and Cotran Pathologic Basis of Disease. 10th ed. Elsevier; 2020.

Please remember this podcast and all content from Rhesus Medicine is meant for educational purposes only and should not be used as a guide to diagnose or to treat. Please consult a healthcare professional for medical advice.