
Hosted by Eugene Borukhovich and Jim Joyce · EN

On this episode of #TheShot of #DigitalHealth therapy, Jim Joyce and I finally sat down with Amy Cosler, a dynamic healthcare leader who rose from old-school hospital sales to driving transformation across Livongo -> Teladoc Health, Lyra Health, and now Carrum Health. Amy shares stories from her early days "carrying a bag" (if you know, you know), navigating to hospital basements with paper maps, transforming a 65-year-old public company, being part of Livongo’s IPO, and leading sales in the exploding employer benefits space. She opens up about resilience, family, leadership, and why kindness and grit are not mutually exclusive. This conversation delivers deep insights for founders, sales leaders, employer-benefit innovators, and anyone navigating the rapidly evolving healthcare economy. 📉 Employers demand real savings ⏱️ Buying cycles are compressing 💸 Utilization pricing opens doors 🤝 Culture drives adoption 🏥 Value-based care delivers impact Fun mentions as always: Jim Pursley, Glen Tullman, Sean McBride, David Ebersman and many more... 00:00 – Opening banter; year-end episodes; creative side projects 03:00 – Introducing guest Amy Cosler 04:00 – Early life: oldest of four, Illinois upbringing, healthcare family roots 05:30 – First job: carrying the bag for Medaflex; 4:00 AM training rides; selling skin-prep products 09:00 – Early sales journey; winning President’s Club; joining Baxter 11:00 – Intrapreneurial experience: building a startup inside Allegiance 13:00 – Cardinal Health acquisition; leadership influences 15:00 – Transformation at Landauer; building radiation monitoring + medical physics business 20:00 – Culture shock moving from startups to legacy healthcare 23:00 – Deep dive into early clinical sales environment (maps, suits, coffee, meetings) 27:00 – Divestiture, financial success, personal reset 28:00 – Meeting her husband; triathlons; writing the first version of her book 30:00 – Enter Livongo: shifting from hospitals to employer benefits 33:00 – Livongo culture, mission focus, member empathy 35:00 – Teladoc acquisition; overnight customer communications 38:00 – Pivot to Lyra; leading sales in mental health 39:30 – Joining Carrum; value-based care for surgery, cancer, SUD 41:00 – Employer trend challenges; cost inflation; need for bold solutions 45:00 – The misconception that kindness isn’t compatible with toughness 46:00 – Lessons for entrepreneurs selling to employers 49:00 – PEPM vs utilization-based pricing 51:00 – Looking ahead; entrepreneurial future; completing her book 52:00 – Jim’s narrative future-casting question 54:00 – Amy’s emotional answer: focus on family 55:00 – Closing and thank you

This week on #TheShot of #digitalHealth Therapy, Jim Joyce and I sat down with someone who might just change how we all understand… well, everything. Because when you think “future of health tech,” your brain probably doesn’t jump to noses in petri dishes. But maybe it should. We hosted Brian Lin, a Tufts researcher and a co-founder of Cellsor, who is literally growing living smell tissue to build the world’s first biological smell "camera". Yes - a "camera" for scent. Think RGB for odors… except instead of 3 channels, humans have 400, dogs have 700, elephants have 2,000, and Jim has… well, that’s still in peer review. 😅 Some highlights: 🧠 Humans have 400 smell receptors - meaning we “smell in 400 dimensions,” far beyond what we can verbally describe. 👃 Most people begin losing smell sensitivity in their 50s–70s without realizing it. 🛡️ The same tech could detect explosives, chemical threats, or hazardous compounds at checkpoint distance. 🔬 Brian’s company uses living tissue, not electronic sensors - truly an actual biological nose. 📡 The system aims to create the world’s first universal smell-recording “camera.” 💡 Future applications span diagnostics, food science, perfumery, defense, and everyday consumer tech. The science is wild, the implications are massive, and the conversation? Pure fun. 🎧 Give it a listen - and trust me, this one will stay with you in ways you can’t quite describe… because we don’t yet have the right vocabulary for smell. Fun mentions as always: Laura Hamilton Daniel Couchman Kendall #healthcare #digitalhealth #biotech #innovation #futureofwork #AI #sensorytech 00:00 – 02:10 Thanksgiving Banter & Show Opening Eugene and Jim share Thanksgiving plans, travel updates, and open the episode. 02:10 – 03:20 Scoop of Thanks Story A heartwarming story about cancer survivors bringing ice cream to oncology staff. 03:20 – 04:25 Introducing Brian Lin Jim recounts meeting Brian at Boston Startup Week over beer and ham sandwiches. 04:25 – 06:15 How Brian Meets People (The Whiskey Method) Brian explains his tradition of bringing whiskey to conferences to meet people. 06:15 – 07:45 Brian’s Background Growing up in Reading, Massachusetts; parents immigrating from China. 07:45 – 10:20 Childhood Pyro Stories Thermite experiments, accidental bed fires, and early science curiosity. 10:20 – 12:20 Education Path Undergrad at RPI, moving to Tufts for a PhD, meeting his wife. 12:20 – 15:00 From Cancer Lab to Smell Research Why cancer signaling wasn’t a fit and how he discovered the olfaction lab. 15:00 – 17:00 The Beer That Improves Dissections A lab story about shaky hands, a Corona with lime, and perfect dissections. 17:00 – 21:00 Understanding Smell Biology Why smell matters, how neurons regenerate, and why people lose smell with age. 21:00 – 24:00 COVID and Smell Loss How COVID reprograms smell neurons, parosmia, and Brian losing smell in Scotland. 24:00 – 28:00 Smell, Culture, Memory, and Diagnosis How smell connects to emotion, depression models, and historical healing. 28:00 – 32:00 Dogs Detect Cancer; Human Nose Complexity Why electronic noses fail and how humans actually smell in 400 dimensions. 32:00 – 35:00 Growing a Living Nose in a Dish Founding CellSaur and using real biological tissue instead of sensors. 35:00 – 38:20 Applications and the Smell Camera Concept Recording smells like RGB/hex codes and connecting to perception models. 38:20 – 41:10 Business Strategy for Smell Tech Three-step pathway: R&D tools, security/defense, and medical diagnostics. 41:10 – 45:00 Market Imagination Future possibilities like airport screening, drones, and household smell libraries. 45:00 – 47:00 Fundraising as a First-Time Founder Brian shares what it’s like shifting from academia into startup fundraising. 47:00 – 50:00 Final Question and Advice Jim gives a future scenario; Brian answers with “hold your conviction.”

On this 3d long-form edition of #TheShot of #DigitalHealth Therapy, Jim Joyce and I had the privilege of sitting down for an unforgettable deep dive with Tim Wentworth, the candid, thoughtful, fiercely grounded and recently retired CEO of Walgreens (previously CEO of Evernorth Health Services). Tim’s story reads like a masterclass in leadership and life itself - from sweeping parking lots in Rochester to leading global healthcare giants like Cigna’s Evernorth and Walgreens. Across nearly two hours (and honestly, we could’ve gone four), Tim brought raw honesty, wisdom, and humor to every story - from his early scholarship thanks to a teacher who believed in him, to leading multi-billion dollar companies but always defining what it means to lead with heart. This is not just a leadership interview - it’s a living case study in resilience, humility, and purpose. 🧠 Key Takeaways 🔥 From parking lots to the C-suite 🏢 The birth, growth, and controversy of PBMs 💊 Merck - Medco, and the spin-off that changed healthcare 💼 Crisis leadership 101 💰 Cigna, Evernorth, and the end of rebates? 🏪 Walgreens, reinvention, and going private 💡 The power of asking for help 🎯 Leadership as legacy Fun mentions as always: Shaine Borukhovich Jay Parkinson, MD, MPH Dr Jack Kreindler Roberto Ascione Mark Cuban Robert Pellegrini Glen Stettin, MD David Snow Kenny Klepper David Benshoof Klein Richard Lungen Frank Sheehy David Cordani Neal Sample Per Lofberg 00:00 — Cold open: Parking-lot beginnings & the teacher who changed Tim’s life 06:20 — Early career: Music industry, Pepsi, Mary Kay, discovering healthcare 13:40 — Joining Medco: First exposure to healthcare operations 21:10 — PBM history: Why PBMs exist, why pharma once owned them, and why that broke 31:55 — Merck → Medco spinout: Fixing the original conflict of interest 41:12 — Express Scripts: Crisis moments, lawsuits, leadership under fire 50:28 — Cigna acquisition: Building Evernorth and changing the role of services 01:02:00 — The “no more rebates” move: What it means and why it matters 01:15:45 — Why Tim came out of retirement to lead Walgreens 01:20:50 — Was he brought in to take Walgreens private? 01:29:30 — Running a 300,000-person company vs. running a PBM 01:38:40 — The future of community pharmacy & neighborhood care 01:46:10 — Startups, AI, and what founders keep getting wrong 01:54:50 — Leadership legacy & advice to his younger self