← The Clay Travis and Buck Sexton Show
The Clay Travis and Buck Sexton Show
Wellness Unmasked: Dr. Nicole Saphier’s 2026 Blueprint for Sustainable Health & Lasting Change
00:22:31
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- [00:00]
Carolyn
I'm Carolyn. I have metastatic breast cancer. I was concerned after my diagnosis. Cascali gives me more life for living. Since I've been prescribed, I've seen a daughter get married. I now have a grandchild and another one on the way.
- [00:11]
Cascali Medication Advertisement Voice
Qasqali ribociclib 200mg tablets with hormone therapy is for adults with HR positive HER2 negative metastatic breast cancer do not take with tamoxifen. In a clinical study at 80 months, women taking Cascali plus letrozole lived over a year longer versus letrozole alone. Individual results may vary. Cascali may cause serious skin reactions, liver problems and low white blood cell counts that may result in serious infections. Life threatening lung problems and abnormal heartbeats can occur. Your doctor should test your heart and blood before and during treatment. Tell your doctor if you have new or worsening cough, chest pain or dizziness before taking gasqali. Tell your doctor all your medical conditions, medicines you take and if you're breastfeeding, pregnant or planning to be sick and harm an unborn baby. Common side effects include nausea, headache and tiredness. Real patient compensated for her time. Learn more@cascali.com 10 athletes will face the.
- [01:02]
Trainer Games Narrator
Toughest job interview in fitness that will push past physical and mental breaking points. You are the fittest of the fit. Only one of you will leave here with an IFIT contract worth $250,000.
- [01:19]
Dr. Nicole Safire
This is where mindset comes in.
- [01:21]
Trainer Games Narrator
Someone will be eliminated.
- [01:23]
Dr. Nicole Safire
Pressure is coming down.
- [01:26]
Public Investing Advertisement Voice
Trainer Games on Prime Video January 8th.
- [01:28]
Kalpen Suresh
Watch the trailer on trainergames.com did you.
- [01:31]
LG Gram Advertisement Voice
Know Microsoft has official ended Support for Windows 10? Upgrade to Windows 11 with an LG Gram laptop voted PCMag's Reader's Choice Top Laptop Brand for 2025. Thin and ultra lightweight, the LG Gram keeps you productive anywhere and Windows 11 gives you access to free security updates and ongoing feature upgrades. Visit lgusa.com iheart for great seasonal savings on LG Gram laptops with Windows 11. PCMag reader's choice used with permission. All rights reserved.
- [02:00]
Public Investing Advertisement Voice
Support for the show comes from Public, the investing platform for those who take it seriously. On public, you can build a multi asset portfolio of stocks, bonds, options, crypto and now generated assets which allow you to turn any idea into an investable index. With AI it all starts with your prompt. From renewable energy companies with high free cash flow to semiconductor suppliers growing revenue over 20% year over year, you can literally type any prompt and put the AI to work. It screens thousands of stocks, builds a one of a kind index and lets you back test it against the S and p. Then you can invest in a few clicks. Generated assets are like EFTs with infinite possibilities, completely customizable and based on your thesis, not someone else's. Go to public.com podcast and earn an uncapped 1% bonus when you transfer your portfolio. That's public.com podcast paid for by Public Investing Brokerage Services by Open to the Public Investing Inc. Member FINRA SIPC Advisory Services by Public Advisors, llc SEC Registered Advisor Generated Assets is an interactive analysis tool. Output is for informational purposes and is not investment recommendation or advice. Complete disclosures available at public.com disclosures hey audiobook lovers.
- [03:11]
Kalpen Suresh
I'm Kalpin.
- [03:12]
Ed Helms
I'm Ed Helms.
- [03:13]
Kalpen Suresh
Ed and I are inviting you to join the best sounding book club you've ever heard with our new podcast, Irsay The Audible and iHeart Audiobook Club.
- [03:22]
Ed Helms
Each week we sit down with your favorite iHeart podcast hosts and some very special guests to discuss the latest and greatest audiobooks from audible.
- [03:31]
Kalpen Suresh
Listen to Earsay on America's number one podcast network, iHeart. Follow Ears, say, and start listening on the free iHeartradio app today.
- [03:43]
Dr. Nicole Safire
Welcome to Wellness Unmass. I'm Dr. Nicole Safire and this is the last episode of 2025 here at Wellness Unmask with Dr. Nicole Safire. We launched in the spring, I think it was late spring, early summer of 2025. It has been a steep learning curve figuring out this whole podcast thing. I am young and I feel like I'm even more young at heart, but I'll tell you, I am not the most technologically savvy. So heading into 2026, I have big goals for myself of continuing to evolve on this platform and trying to bring you as much real and honest content as possible, making sure to get some fantastic guests that only expands your knowledge and horizons, but mine as well, because there's always more for us to learn. But I wanted to, for this last 2025 episode, just talk to you a little bit about what we can all do to get to a little bit of a healthier place. I for one, I hate New Year's resolutions. I really do, because they fail. But let's be honest. We all head into 2026. We have big goals, big plans come February, come March. Do you even think about those resolutions anymore? Probably not, because it's hard for a lot of us too. So listen, there's a familiar pressure in the air. A new year, a new you. You're seeing all of the Things online, on tv, people are talking about it. But let me be very clear right from the start, you do not need to reinvent yourself to live a healthier and happy life. You just don't. Every January, I really see the same pattern. Extreme diets, unrealistic workout goals, supplement overload, and a whole lot of guilt by the time that February March rolls around. And as a physician, I'm going to tell you, this approach, this extremism, it's going to fail. It is. So this year I would like to challenge you to do something different. I know you've heard me talk about this before because I feel strongly about it. Instead of a total overhaul, let's just focus on some small strategic and science backed, of course, shifts that can actually move the needle on health, physically, mentally, metabolically, all of those things. So let's talk about it. Research consistently shows that over 80% of New Year's resolutions fail by February. I mean, that's, that's pretty big. February. Really? We couldn't even get to like Q2 April? Nope, it's February. And it's not because people are lazy, but because the goals sometimes are too vague. Most of the time they're way too extreme and they're rooted in punishment instead of Progress. Like, lose 30 pounds in six months, work out every day, never eat sugar ever, ever, ever again. That's not behavior change, that's like burnout. But on a calendar, your brain and your body, they're wired for consistency, not shock therapy. You'd think we learned from the 70s, 60s. Shock therapy doesn't work. So we need to actually make some, you know, more manageable, consistent things that are better for long term because when we go too hard, too fast. Cortisol, you know, our stress hormones, our fight or flight, cortisol, epinephrine, norepinephrine, those all spike. And while it's great in the short term for those brief bursts of energy we need, like if we see a black bear and we need to run, but it's terrible for the long term for your health because your sleep suffers, your inflammation increases, because cortisol makes those blood sugar spikes. And that's not just for diabetics, that's anyone makes your blood sugar spike. We know blood sugar rise in blood sugar increases our bodily inflammation, and bodily inflammation increases autoimmune disease, poor gut health, poor sleep, feeling sluggish, cancer, just about everything. Heart disease, dementia, you name it, it's caused by inflammation. And ironically, when you do stuff like that, weight loss and metabolic health get much worse. Not better. So you may be doing this, like shock therapy, thinking you're doing something good for your body, but it's not, especially not in the long term. So instead of asking yourself, what do I want to change about myself? Ask, what does my body need more of? What does it need less of? That shift alone can reframe health from punishment to partnership. I mean, think of your body as a vessel. You have one vessel for this life. You better do all you can to take care of it. For me, I've really had to just stop drinking wine altogether. And that's not because I said, all right, that's it. I need to lose 10 pounds. And so therefore, I'm not drinking wine anymore. I haven't done that. What I have done is I've noticed over the last year, if I were to have a glass of wine that night, I would get, like, night sweats. I'd almost wake up. Like, I felt like I had a fever. Like, my body was like, ugh, get this out of me. These toxins are awful. And I don't know if it was the sugar, the tannins, whatever it is about wine, it wasn't making me feel good. I was. It was keeping me up at night. I was waking up in the morning feeling like I had a bottle instead of a glass. So I made the conscious decision to say, not that, oh, you're never allowed a glass of wine again. It's just, why would I continue to drink wine if it makes my body feel this way? And I really, for the most part, cut it out. So those are kind of the meaningful shifts that I want you to focus on what makes your body feel good, if it feels good, maybe you should do some more of it. And now I'm not talking about, you know, things that make your body feel good in a harmful way. I'm talking about good things. You know, what makes you feel bad? Are there certain foods that you find yourself just not doing well at night? You're having a hard time falling asleep, staying asleep. When you wake up, you don't feel very well. Maybe keep a little bit of a food diary that you can mention some of the foods and drinks and even things that you do during the day, you know, what makes you feel good, what makes you feel bad. And if you do that for, I don't know, a couple of weeks, even a month, you can look back at that and you can find some patterns and figure out what your body really wants. And so, you know, we talk a lot about food and exercise and that directly Affects our sleep. But sleep. I know you've heard me say this. At nausem, sleep is so crucial because poor sleep disrupts just about everything. It disrupts insulin sensitivity, increases hunger hormones. It lowers our leptin, which is a hunger hormone, and it drives cravings for sugar and processed food. It also weakens immune function and worsens anxiety and depression. It does. I know I keep talking about get your sleep. And it's not just because I want you to feel awake the next morning. I'm telling you, your body rests and restores while it's sleeping. So I think one of the big goals should be protect your sleep like it's medicine, because it absolutely is. And simple, realistic steps like aim for a consistent bedtime. Because the reality is it's not just how long you sleep every night, it's how consistent you are with your sleep patterns. Because your body, the hormones go on a cycle, so you want to maintain your circadian rhythm. So if you like to go to sleep at 10 o', clock. I personally like to go to sleep at 9 o', clock, but I'm an early bird and that's okay. But if you like to go to sleep at 10 o', clock, just try to go to sleep at 10 o' clock every night, not just Monday through Friday, and then party hardy on the weekends. Try to go to sleep at 10 o' clock Monday through Sunday. And fine, if that's too early for you, make it 11 o'. Clock. But your body really does want at least seven to nine hours of sleep. You know, eight to nine hours is that golden magical number. But equally as important is getting to sleep around the same time every night. You want to stop scrolling at least 30 minutes before bed. Honestly, you should try to stop scrolling three hours before bed. But for some people, that's impossible. Keep your room cool and dark. Sleeping when it's colder in your room, you know, sleeping without clothes on, that actually helps boost your metabolism while you're sleeping, when you're just feeling a little bit chilly, your body kind of kicks into gear. And you never know, you might be burning calories while you sleep. Wouldn't that be the perfect way to burn some calories? And if you find yourself like your mind is racing at night and you're just laying in bed, don't turn on the tv, don't grab for your phone, because that light is going to completely disrupt your circadian rhythm. It's gonna stop what's happening with your melatonin and your serotonin and all of that. So you really wanna keep that light away. You can grab a book if you want that. You can also start writing things down if you find yourself like coming up with a list. I have to do this, I need to do this, and such and so forth. Instead of trying to keep it all in your brain, take it out of your brain and write it down on a piece of paper. It'll be there in the morning. You can focus it on in the morning. But try to remove some of that stress physically from your brain by writing it down. Because all that does is just stress you out. And chronic stress is one of the most underestimated health threats we have. Stress just, it's not just emotional, it's physiological. It raises our cortisol. We talked about that. Which drives inflammation, disrupts our digestion, and it increases cardiovascular risk. It also increases the risk for cancer, for dementia and other things. Inflammation is bad. Stress causes inflammation. Bad, bad. So I'm not gonna tell you you need to eliminate stress because obviously that's impossible, but you can change how your body responds to it. So sometimes this is hard for me, but I do try to just take a pause and some of the daily stress reset tools that I find that actually work. 10 minute walk outside. Getting outside. Did you know that just being in nature and being surrounded by nature is, has shown to decrease cortisol levels? I know that sounds silly, but just get yourself outside. Not only does it give you that little bit vitamin D, which we are all low on during the wintertime, I guess, except if you're living in the Southwest, they seem to have unseasonably warm and sunny temperatures right now. But for the rest of us, we're living in some state of 50 shades of gray and not the sexy type. So we're all low on vitamin D, which affects our bone health, it also affects our brain health and it affects our mental health. So getting outside, rolling up your sleeves a little bit, trying to get that vitamin D, maybe even taking vitamin D supplements that can help with that. But just being outside not only helps with vitamin D, but it can decrease your cortisol. Deep breathing exercises where you really just focus, you close your eyes, you take a big deep breath in, you hold it for a minute. Not a minute. Excuse me. Don't do that. I have a hard time holding it. Hold it for a few seconds and, and then slowly exhale. Because when you are exhaling, not only are you getting rid of that carbon dioxide and making more room for the oxygen that's going to now supply much needed nutrients and oxygen throughout your entire body, but you can think of your exhale as just some of that stress leaving your body. Deep breathing really does have a physiological effect on your body. It could decrease blood pressure, it could, it can improve your mood and it can really help decrease those cortisol levels. So stopping for a few minutes a day, just put yourself into a quiet area. Just trying to focus and recenter on what's going on with you and focus on your breathing instead of the chaos around you can be helpful. Also, finding some creative hobbies, listening to music or just quiet time without stimulation, that can all be a good thing. I personally absolutely love reading a good book. I'll be honest, I haven't done leisurely reading in almost a year because I have been writing a book and that's one of my things. When I'm writing a book, I can't be leisurely reading. I have to focus on what I'm writing. So I just turned something in to my editor within the last week and I'm so excited to get back to reading because I miss it so much. I already have about eight books picked out that I plan to read hopefully in the next few months More Coming up on Wellness unmasked with Dr. Nicole Safire.
- [16:07]
Carolyn
I'm Carolyn. I have metastatic breast cancer. I was concerned after my diagnosis. Cascali gives me more life for living. Since I've been prescribed, I've seen a daughter get married. I now have a grandchild and another one on the way.
- [16:19]
Cascali Medication Advertisement Voice
Gascali ribociclib 200 milligram tablets with hormone therapy is for adults with HR positive HER2 negative metastatic breast cancer do not take with Tamoxife. In a clinical study at 80 months, women taking Cascali plus letrozole lived over a year longer versus letrozole alone. Individual results may vary. Cascali may cause serious skin reactions, liver problems and low white blood cell counts that may result in serious infections. Life threatening lung problems and abnormal heartbeats can occur. Your doctor should test your heart and blood before and during treatment. Tell your doctor if you have new or worsening cough, chest pain or dizziness before taking Kaskali. Tell your doctor all your medical conditions, medicines you take and if you're breastfeeding, pregnant or planning to be as it can harm an unborn baby. Common side effects include nausea, headache and tiredness. Real patient compensated for her time. Learn more@cascali.com.
- [17:10]
Ed Helms
Hey everyone, Ed Helms here.
- [17:13]
Kalpen Suresh
And hi, I'm Kalpen and we're the hosts of Irsay, the Audible and iheart.
- [17:18]
Ed Helms
Audiobook Club this week on the podcast, I am sitting down with Jenny Garth, host of the iHeart podcast. I choose me to discuss the new Audible adaptation of the timeless Jane Austen classic Pride and Prejudice. This is not a trick question. There's no wrong answer. What role would I play?
- [17:40]
Dr. Nicole Safire
You know what? I can see you as Mr. Darcy. You got a little call in first.
- [17:46]
Ed Helms
Okay, that's really sweet. I appreciate that. But are you sure I'm not the dad? I'm not Mr. Bennett. Here, listen to earsay the Audible and iHeart Audiobook Club on the iHeartradio app or wherever you get your podcasts.
- [18:06]
Trainer Games Narrator
Ten athletes will face the toughest job interview in fitness that will push past physical and mental breaking points. You are the fittest of the fit. Only one of you will leave here with an IFIT contract worth $250,000.
- [18:25]
Dr. Nicole Safire
This is where mindset comes in.
- [18:27]
Trainer Games Narrator
Someone will be eliminated.
- [18:29]
Dr. Nicole Safire
Pressure is coming down. Trainer Games on Prime Video January 8th.
- [18:34]
Kalpen Suresh
Watch the trailer on trainergames.com did you.
- [18:36]
LG Gram Advertisement Voice
Know Microsoft has officially ended Support for Windows 10 upgrade to Windows 11 with an LG Gram laptop, voted PCMag's Reader's Choice top laptop brand for 2025. Thin and ultra lightweight, the LG Gram keeps you productive anywhere and Windows 11 gives you access to free security updates and ongoing feature upgrades. Visit lgusa.com iheart for great seasonal savings on LG Gram laptops with Windows 11. PCMag reader's choice used with permission. All rights reserved.
- [19:06]
Public Investing Advertisement Voice
Support for the show comes from Public, the investing platform for those who take it seriously. On Public, you can build a multi asset portfolio of stocks, bonds, options, crypto and now generated assets which allow you to turn any idea into an investable index with AI. It all starts with your prompt. From renewable energy companies with high free cash flow to semiconductor suppliers growing revenue over 20% year over year. You can literally type any prompt and put the AI to work. It screens thousands of stocks, builds a one of a kind index and lets you back test it against the S&P 500. Then you can invest in a few clicks. Generated assets are like EFTs with infinite possibilities, completely customizable and based on your thesis, not someone else's. Go to public.com podcast and earn an uncapped 1% bonus when you transfer your portfolio. That's public.com podcast paid for by Public Investing Brokerage Services by Open to the Public Investing Inc. Member FINRA SIPC Advisory Services by Public Advisors, llc. SEC Registered Advisor Generated Assets is an interactive analysis tool output is for informational purposes only and is not investment, recommendation or advice. Complete disclosures available at public.com disclosures.
- [20:17]
Dr. Nicole Safire
I also listen to music when I'm at work. When I walk into my office in between seeing patients, my music is playing. And it does just give me that little bit of sense of relaxation. I'd love to pick up a hobby. I don't really know what it is. I did start my chickens in the last couple of years. I created an amazing vegetable garden this last year. You know, I don't know what 2026 is going to hold for me. Maybe I'm going to expand on my gardening or something. Whatever it is, I just hope it brings me outside because we just do not get outside enough. So, you know, I'm still thinking about it. I don't know what it is yet. But another thing, when we talk about trying to feel better, you know, as I talk about my chickens, I have chickens because I want fresh, healthy eggs. I have a vegetable garden and an herb garden because I like to bring that in directly to my family, to feed my family there. Nutrition is obviously very important heading into the new years. So instead of stepping into 2026 saying, all right, I need to cut out my carbs, I need to cut out my calories, I need to cut out my sugar. I basically just need to cut out joy from my diet, that's not what I'm telling you to do. I want you to start by adding, let's. Let's talk about things. Am I getting enough protein? Am I getting enough fiber? No, I can answer that for you. You're not getting enough fiber because Americans never get enough fiber. We've talked about this before. We've talked about things you can do to increase lean protein, increase fiber, other micronutrients. I'm telling you, whatever you think you're doing, you could be doing more. And your body will truly thank you. Protein is essential for muscle metabolism, your overall metabolism, blood sugar stability, and especially as we age, fiber supports gut health, hormone balance and inflammation control. And our micronutrients are needed all throughout our bodies to help our muscles, help our bones, help our brain. So if your plate is. If you're looking at your dinner plate, your, you know, your lunch plate, your breakfast plate, there should be half vegetables or half fruits, a solid protein source, some healthy fats. If you have that, you are already winning. And no, this doesn't require perfection. But I am a big believer in the whole 80, 20 approach. You eat well most of the time. Like, 80% of the time. And then 20% of the time, you know, you can have like, I don't know, I was eating some Hershey Kisses earlier. I love chocolate, what can I say? But I also make sure that I had a healthy breakfast this morning full of eggs and blueberries and I had a fiber rich smoothie. So I'm ready to live the rest of my life. And if I want to have some chocolate this afternoon, I golly, I did, because I want to. So we've heard and learned a lot about ultra processed foods recently. The Make America Healthy again movement with RFK Jr. Obviously they've talked a lot about it and maybe you never heard that term before, but now, I mean, it's everywhere. And no, they didn't just happen. They're just finally being talked about. We don't need to be obsessive over it. But reducing the amount of ultra processed foods is one of the most important, powerful health moves you can make. These foods are engineered to override the feeling of fullness and disrupt metabolic signaling. They are honestly designed for you to eat them and then make you want to continue eating more. No wonder we have an obesity crisis here in the United States. Our food's designed to make us do that. It's horrible. So what are these ultra processed foods? It's pretty much everything in the center of the grocery store. If it can sit in your pantry for more than a couple of months, it's probably ultra processed. Unless obviously canned, canned vegetables and stuff, those can sit longer, but oftentimes those have a lot of salt in them. So you really want to watch all that content. So let's start small. However many packaged goods, sugar sweetened beverages, whatever you have in your pantry or whatever you have in your daily life, you don't need to cut it out. Why don't you just cut back a little bit? If you stop at Starbucks and you get those sugary drinks five days a week, Lord help you, I hope you don't do that. But if you do, maybe we cut back maybe like two days a week. That would be monumentous. And maybe next year we can talk about cutting back altogether because those sugary drinks, terrible for you. But there's no need to be extreme. In fact, it's not realistic to be extreme. So let's just cut back a little bit. Okay? And the last thing I really want to touch on, don't overthink it, okay? You don't need to go and get a new gym membership to be healthier. Movement is medicine. It doesn't have to be extreme. The Biggest benefits from consistency, strength training and just daily movement. Walking incredibly underrated because walking especially like fast walking improves cardiovascular health, insulin sensitivity, mental health and longevity. Strength training. Yes. Yes ladies, you too. We all need to be lifting weights right now because as we get older, especially women, our bone density goes down and strength training not only builds our muscles but it helps protect our bones. So if you are not lifting weights and you are in your 40s, in your 50s, in your 60s, you are not doing your body justice. And that is one thing you need to start doing this year is start lifting some weights. That doesn't mean you have to go be a weightlifter fitness model and it just means get some five bound dumbbells, keep em in your, keep em in your office, keep em in your bedroom, wherever it is. Start lifting some weights, try and build some muscle. Working out with a trainer is a great thing if you have the time and money to do it. I love working out with trainers, but it's not realistic for me because I cannot keep an appointment to save my life. So I just really try to. I have some hand weights in my office at the hospital and anytime I can, I start lifting some weights. I like to do lunges, I like to do anything I can to keep my body moving during the day. And I know I said that was the last thing we were gonna talk about, but I'm sorry, I forgot. We gotta talk about one more big thing because as we head deeper into the winter, the immunity is top of mind. I mean I'm sure you've seen the headlines. We're like max capacity when it comes to flu right now. So let's support our immune health because flu season is not over until March. Yes, right now is terrible, but it continues on for another couple of months. So supporting our immune health. Yes, it can be supported with supplements, but it's not just about, you know, taking that emergency or whatever it is. There's no amount of vitamin C that's gonna protect you if you aren't taking care of other aspects of your body. So adequate sleep. We already mentioned that. Nutrient dense foods. Think of eating the colors of the rainbow. Blueberries, raspberries, bananas, apples, all those things, A bunch of different colors, have all various different nutrients that all work in different ways to boost your immune system. Make sure you're eating them. Stress management. The more stressed you are, the more cortisol you have. And cortisol directly dampens your immune system. So if you're stressed out because you don't have enough time to do stuff you're going to get sick and then you're going to be even more stressed out and it's going to be a very dangerous cycle. So you gotta gotta calm down, gotta figure out how to manage that stress just a little bit. You know, I love certain herbs and botanicals. I created Droprx because of this. I love specifically for relaxation and brain health. Some beauty stuff to help my hair, skin and nails. But again that no amount of supplement is going to stop you from being sick if you aren't managing some of the other stuff. And all of this kind of is a way to focus on supporting your physical and mental health. Because health is not just physical loneliness, social isolation. These are all major public health risks comparable to smoking in terms of mortality impact. So as we move into the new year, let's ask ourselves what fills my cup? What makes me feel good? What doesn't make me feel good? Who fills my cup? Is there a certain person who makes me feel good? Is there a certain person who doesn't make me feel good? Maybe I don't need to be around those people anymore. Maybe I should spend more time with people who actually make me feel good and I don't walk away from them feeling more stressed out. Do I need to set better boundaries somewhere? You know, sometimes we deal with this sometimes, whether it's family or friends or whatever it may be, sometimes we really do need to focus on ourselves. And sometimes that means spending less time with others and more time maybe with your immediate family, maybe just with yourself. Protecting your mental health may mean saying no more often, absolutely reducing screen time. You know, at the beginning of December I tried to do that myself. And really just spending more time with people who ground you resting. It's not being lazy boundaries, it's not being selfish. It's what we need for long term health if we really want to take it seriously and feel better. We don't need extremes, we don't need perfection and we really don't need to feel guilty. But what we do need is better sleep, less stress, more real food, more movement and just more compassion for ourself. Health. And definitely long term health. It is not built in January alone. It's built in the quiet, consistent choices you make really when no one's watching. It's not a resolution. It's kind of the deal you're making with yourself this year. I implore you, let's both aim for some progress that we can sustain, not changes that we can barely tolerate. Okay, you do it, I do it, we'll do it. Together and we'll continue to check in. How are we feeling? If you have any things that are working for you, make sure you reach out to me on X or Instagram. I want to hear what's working for you and if something's working for me or if something's not working for me, I'm going to let you know as well. Thanks so much for joining me on Wellness on Mass. I'm Dr. Nicole Safire. Happy New Year. I will see you in 2026. Make sure to catch Wellness on Mass with Dr. Nicole Saffire on iHeartRadio and wherever you get your podcasts and I will see you next year.
- [30:18]
Carolyn
I'm Carolyn. I have metastatic breast cancer. I was concerned after my diagnosis. Cascali gives me more life for living since I've been prescribed. I've seen a daughter get married. I now have a grandchild and another one on the way.
- [30:30]
Cascali Medication Advertisement Voice
Gascali ribociclib 200 milligram tablets with hormone therapy is for adults with HR positive HER2 negative metastatic breast cancer do not take with Tamoxifen in the clinical In a clinical study at 80 months, women taking Cascali plus letrozole lived over a year longer versus letrozole alone. Individual results may vary. Qasqali may cause serious skin reactions, liver problems and low white blood cell counts that may result in serious infections. Life threatening lung problems and abnormal heartbeats can occur. Your doctor should test your heart and blood before and during treatment. Tell your doctor if you have new or worsening cough, chest pain or dizziness before taking Cascali. Tell your your doctor all your medical conditions, medicines you take and if you're breastfeeding pregnant or planning to be sick and harm an unborn baby. Common side effects include nausea, headache and tiredness. Real patient compensated for her time.
- [31:17]
Kalpen Suresh
Learn more@cascali.com hey audiobook lovers, I'm Cal Penn.
- [31:21]
Ed Helms
I'm Ed Helms.
- [31:22]
Kalpen Suresh
Ed and I are inviting you to join the best sounding book club you've ever heard with our new podcast, Irsay The Audible and iHeart Audiobook Club.
- [31:31]
Ed Helms
Each week we sit down with your favorite iHeart podcast hosts and some very special guests to discuss the latest and greatest audiobooks from Audible.
- [31:40]
Kalpen Suresh
Listen to HearSay on America's number one podcast network, iHeart Followersay and start listening on the free iHeartRadio app.
- [31:48]
Trainer Games Narrator
Today, 10 athletes will face the toughest job interview in fitness that will push past physical and mental mental breaking points. You are the fittest of the fit. Only one of you will leave here with an IFIT contract worth $250,000.
- [32:08]
Dr. Nicole Safire
This is where mindset comes in.
- [32:10]
Trainer Games Narrator
Someone will be eliminated.
- [32:12]
Dr. Nicole Safire
Pressure is coming down. Trainer Games on Prime Video January 8th.
- [32:17]
Kalpen Suresh
Watch the trailer on trainergames.com did you.
- [32:20]
LG Gram Advertisement Voice
Know Microsoft has officially ended Support for Windows 10? Upgrade to Windows 11 with an LG Gram laptop, voted PCMag's reader's choice top laptop brand for 2025. Thin and ultra lightweight, the LG Gram keeps you productive anywhere, and Windows 11 gives you access to free security updates and ongoing feature upgrades. Visit lgusa.com iheart for great seasonal savings on LG Gram laptops with Windows 11. PCMag reader's choice used with permission. All rights reserved.
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Public Investing Advertisement Voice
Support for the show comes from Public, the investing platform for those who take it seriously. On Public you can build a multi asset portfolio of stocks, bonds, options, crypto and now generated assets which allow you to turn any idea into an investable index with AI. It all starts with your prompt. From renewable energy companies with high free cash flow to semiconductor suppliers growing revenue over 20% year over year, you can literally type any prompt and put the AI to work. It screens thousands of stocks, builds a one of a kind index and lets you back test it against the S&P 500. Then you can invest in a few clicks. Generated assets are like EFTs with infinite possibilities, completely customizable and based on your thesis, not someone else's. Go to public.com podcast and earn an uncapped 1% bonus when you transfer your portfolio. That's public.com podcast paid for by Public Investing Brokerage Services by Open to the Public Investing Inc. Member FINRA SIPC Advisory Services by Public Advisors llc. SEC Registered Advisor Generated Assets is an interactive analysis tool. Output is for informational purposes only and is not investment recommendation or advice. Complete disclosures available at public.com disclosures.