
Loading summary
Carolyn
I'm Carolyn. I have metastatic breast cancer. I was concerned after my diagnosis. Cascali gives me more life for living. Since I've been prescribed, I've seen a daughter get married. I now have a grandchild and another one on the way.
Pharmaceutical Announcer
Qasqali ribociclib 200mg tablets with hormone therapy is for adults with HR positive HER2 negative metastatic breast cancer do not take with tamoxifen. In a clinical study at 80 months, women taking Cascali plus letrozole lived over a year longer versus letrozole alone. Individual results may vary. Cascali may cause serious skin reactions, liver problems and low white blood cell counts that may result in serious infections. Life threatening lung problems and abnormal heartbeats can occur. Your doctor should test your heart and blood before and during treatment. Tell your doctor if you have new or worsening cough, chest pain or dizziness before taking gascali. Tell your doctor all your medical conditions, medicines you take and if you're breastfeeding, pregnant or planning to be sick and harm an unborn baby. Common side effects include nausea, headache and tiredness. Real patient compensated for her time.
Kal Penn
Learn more@cascali.com hey audiobook lovers, I'm Kal Penn.
Ed Helms
I'm Ed Helms.
Kal Penn
Ed and I are inviting you to join the best sounding book club you've ever heard with our new podcast, Earsay, the Audible and iHeart Audiobook Club.
Ed Helms
Each week we sit down with your favorite iHeart podcast hosts and some very special guests to discuss the latest and greatest audiobooks from Audible.
Kal Penn
Listen to hearsay on America's number one podcast network, iHeart. Follow earsay and start listening on the free iHeartradio app today.
Trainer Games Narrator
Ten athlet will face the toughest job interview in fitness that will push past physical and mental breaking points. You are the fittest of the fit. Only one of you will leave here with an IFIT contract for $250,000. This is where mindset comes in. Someone will be eliminated.
Dr. Nicole Safire
Pressure is coming down.
Ed Helms
Trainer Games on Prime Video January 8th.
Kal Penn
Watch the trailer on trainergames.com did you.
LG Gram Advertiser
Know Microsoft has officially ended Support for Window 10? Upgrade to Windows 11 with an LG Gram laptop voted PCMag's Reader's Choice top laptop brand for 2025 thin and ultra lightweight. The LG Gram keeps you productive anywhere and Windows 11 gives you access to free security updates and ongoing feature upgrades. Visit lgusa.com iheart for great seasonal savings on LG Gram laptops with Windows 11. PCMag reader's choice. Used with permission. All rights reserved.
Unrivaled Basketball Announcer
Season 2 of unrivaled basketball is here and the talent is unreal. The best women's players on the planet are running it back with even bigger moments and bigger stakes. Don't miss as Paige Beckers, Nafiza Collier, Kelsey Plumb, Brianna Stewart and more take the court and redefine the game. This isn't your regular season. This is unrivaled, where the pace is faster, the energy is higher, and every athlete shines. Unrivaled basketball season two, sponsored by Samsung Galaxy, tips off January 5 on TNT, TruTV and HBO. Max.
Dr. Nicole Safire
Welcome to wellness unmasked. I'm Dr. Nicole Safire and this is your weekly rundown. I hope everyone had a wonderful Hanukkah and a very merry Christmas. We got some very sad news from former Nebraska senator Ben Sasse. This week he announced that he has been diagnosed with stage four advanced pancreatic cancer, a disease that he described candidly as a death sentence. In a message to the public, Sass, 53 and a husband and father of three, made it clear just how devastating this diagnosis is and how quickly this disease can progress. Most people don't realize it, but pancreatic cancer is one of the deadliest forms of cancer in the United States. It affects roughly 67,000 people each year, with nearly 51,000 deaths every year, making it the fourth leading cause of cancer death. So what makes pancreatic cancer so deadly? Well, it often causes no symptoms until it's already advanced and by the time it's diagnosed, about 50 to 60% of patients are already at stage four, where treatment options are limited and survival rates are low. The overall five year survival for metastatic pancreatic cancer is in the single digits. We do have treatment options. They are getting better with some of these survival odds, but it is still far below what we would like it to be. So this isn't just a political figure struggle, it's a reflection of a broader public health challenge. We still urgently need better tools at diagnosing and finding this particular cancer early, more research funding and broader access to cutting edge treatments. These are not luxuries. These are necessities. And now shifting from personal health to our entire health system. The millions of Americans who rely on the Affordable Care act health insurance are facing immediate financial stress because expanded ACA subsidies are expiring as of December 31st. Yeah, that's. What is that, less than a week away now, guys. These pandemic era premium tax credits paid for by the taxpayer, slashed costs for millions of individuals and families because it gave a lot of taxpayer dollars to the insurance companies. But now they're set to expire and if we don't renew them, then everyone's premiums are going to go up and it's going to be very expensive for a lot of people. But the answer can't be to just keep giving taxpayer dollars to insurance companies. This is not the way out and con to deal with it. They made this problem, they need to fix it. And as of right now, we see a few bills circulating around Congress they haven't necessarily come in on one. You have the Democratic one, you have the GOP one. The GOP one, in my opinion, still needs some work. We need some people to get together. The Democratic one is dead in the water. It's essentially socialized medicine. We're not going to go with that. So the GOP really needs to get together because Americans will suffer if these subsidies aren't expanded, at least in the short term. I don't think the answer is to continue to throw money at insurance companies. Absolutely not. But something needs to happen because we can't let Americans suffer financially. This is not the time. This is tis the season. So Congress get to work. So this whole policy shift is not abstract. It affects care access at a time when the US Is grappling with rising disease burdens. Cancer, chronic illness, mental health needs. So if people don't have affordable health insurance, they will delay their preventative care. They're going to skip their cancer screenings and they're going to start showing up in emergency rooms sicker and more expensive to treat. I'm Dr. Nicole Safire. This is Wellness Unmass, your weekly rundown. Make sure to listen to Wellness on mass every Tuesday and Friday. You can find it on iheartradio or wherever you get your podcasts. And we will see you next time.
Carolyn
I'm Carolyn. I have metastatic breast cancer. I was concerned after my diagnosis. Cascali gives me more lives for living Since I've been prescribed, I've seen a daughter get married. I now have a grandchild and another one on the way.
Pharmaceutical Announcer
Gascali ribociclib 200 milligram tablets with hormone therapy is for adults with HR positive HER2 negative. Metastatic breast cancer do not take with tamoxifen. In the clinical study, at 80 months, women taking Cascali plus letrozole lived over a year longer versus letrozole alone. Individual results may vary. Coscali may cause serious skin reactions, liver problems and low white blood cell counts that may result in serious infections. Life threatening lung problems and abnormal heartbeats can occur. Your doctor should test your heart and blood before and during treatment. Tell your doctor if you have new or worsening cough, chest pain or dizziness before taking Kaskali. Tell your doctor all your medical conditions, medicines you take and if you're breastfeeding, pregnant or planning to be sick and harm an unborn baby. Common side effects include nausea, headache and tiredness. Real patient compensated for her time. Learn more@cascali.com 10 athletes will face the.
Trainer Games Narrator
Toughest job interview in fitness that will push past physical and mental breaking points. You are the fittest of the fit. Only one of you will leave here with an IFIT contract for $250,000. This is where mindset comes in. Someone will be eliminated.
Dr. Nicole Safire
Pressure is coming down.
Ed Helms
Trainer Games on Prime Video January 8th.
Kal Penn
Watch the trailer on trainergames.com did you.
LG Gram Advertiser
Know Microsoft has officially ended Support for Windows 10? Upgrade to Windows 11 with an LG Gram laptop, voted PC Mag's Reader's Choice top laptop brand for 2025. Thin and ultra lightweight, the LG Gram keeps you productive anywhere and Windows 11 gives you access to free security updates and ongoing feature upgrades. Visit lgusa.com iheart for great seasonal savings on LG Gram laptops with Windows 11. PCMag reader's choice used with permission. All rights reserved.
Unrivaled Basketball Announcer
Season 2 of unrivaled basketball is here and the talent is unreal. The best women's players on the planet are running it back with even bigger moments and bigger stakes. Don't miss as Paige Beckers, Nafiza Collier Kelly, Chelsea Plumb, Brianna Stewart and more take the court and redefine the game. This isn't your regular season. This is unrivaled, where the pace is faster, the energy is higher and every athlete shines. Unrivaled basketball season two, sponsored by Samsung Galaxy, tips off January 5 on TNT, TruTV and HBO.
Ed Helms
Max support for the show comes from Public, the investing platform for those who take it seriously. On Public, you can build a multi asset portfolio of stocks, bonds, options, crypto and now generated assets which allow you to turn any idea into an investable index. With AI, it all starts with your prompt. From renewable energy companies with high free cash flow to semiconductor suppliers growing revenue over 20% year over year. You can literally type any prompt and put the AI to work. It screens thousands of stocks, builds a one of a kind index and lets you back test it against the S&P 500. Then you can invest in a few clicks. Generated assets are like EFTs with infinite possibilities, completely customizable and based on your thesis, not someone else's. Go to public.com podcast and earn an uncapped 1% bonus when you transfer your portfolio. That's public.com podcast paid for by Public Investing Brokerage Services By Open to the Public Investing Inc. Member FINRA SIPC Advisory Services by Public Advisors, llc SEC Registered Advisor Generated Assets is an interactive analysis tool. Output is for informational purposes only and is not investment recommendation or advice. Complete disclosures available at public.com disclosures.
This special "Wellness Unmasked" segment with Dr. Nicole Saphier delivers a timely rundown of high-impact stories at the intersection of health news and U.S. policy. The episode opens with the serious announcement about former Nebraska Senator Ben Sasse’s stage four pancreatic cancer diagnosis and its implications—not only for him, but for the greater challenges of cancer detection and treatment in America. Dr. Saphier then transitions to the looming expiration of expanded Affordable Care Act (ACA) subsidies, exploring the practical and political dimensions of health insurance access for millions of Americans.
(Starts at 03:05)
Announcement & Personal Impact
Dr. Saphier reports on Ben Sasse’s public announcement:
“We got some very sad news from former Nebraska senator Ben Sasse. This week he announced that he has been diagnosed with stage four advanced pancreatic cancer, a disease that he described candidly as a death sentence.”
(Dr. Nicole Saphier, 03:11)
Pancreatic Cancer Statistics
Need for Early Detection and Support
Dr. Saphier highlights the urgency:
“We still urgently need better tools at diagnosing and finding this particular cancer early, more research funding and broader access to cutting edge treatments. These are not luxuries. These are necessities.”
(Dr. Nicole Saphier, 04:38)
(Starts at 04:47)
Upcoming Expiration
Expanded pandemic-era ACA subsidies are set to expire on December 31, causing anxiety for millions who rely on them.
Financial Strain and Systemic Impact
Political Gridlock
Critique of Insurance Structure
Dr. Saphier is clear:
“The answer can't be to just keep giving taxpayer dollars to insurance companies. This is not the way out and [Congress] made this problem, they need to fix it.”
(05:20)
Consequences for Preventative Care
She warns of downstream effects:
“If people don't have affordable health insurance, they will delay their preventative care. They're going to skip their cancer screenings and they're going to start showing up in emergency rooms sicker and more expensive to treat.”
(06:32)
On Pancreatic Cancer’s Stealth:
“It often causes no symptoms until it's already advanced and by the time it's diagnosed, about 50 to 60% of patients are already at stage four...”
(Dr. Saphier, 03:54)
On Survival Rates:
“The overall five-year survival for metastatic pancreatic cancer is in the single digits.”
(Dr. Saphier, 04:29)
On Policy Urgency:
“We can't let Americans suffer financially. This is not the time. This is tis the season. So Congress get to work.”
(Dr. Saphier, 06:10)
Dr. Saphier’s delivery balances sobering statistics and policy critique with urgency and empathy. Her commentary is direct—challenging both lawmakers and the healthcare system to take meaningful action for both cancer research and access to affordable insurance. The episode appeals for bipartisan cooperation and real solutions, warning of dire consequences if political inertia persists.
Those who missed the episode get a succinct snapshot of both a deeply personal health crisis with national implications and the pressing policy debates likely to affect millions in the coming year.