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Dr. Mark Hyman
Coming up on this episode of the Dr. Hyman Show.
Dr. Gabrielle Lyon
Now, after age 30, you lose as much as 5% of your muscle mass per decade. Most men will lose 30% of their muscle mass in their lifetime, but muscle is the organ of longevity.
Unknown Speaker
I'm all about food first, but some.
Dr. Mark Hyman
Nutrients like magnesium are nearly impossible to get enough of through diet alone. Our soils are depleted and things like sugar, caffeine and stress drain our levels. Magnesium supports over 300 functions in the body. Think metabolism, sleep, energy, pain and more. That's why I recommend Magnesium Breakthrough by Bioptimizers. It's the only supplement with all seven forms of magnesium for full body support. Get 10% off at bioptimizers.com hyman with code HYMAN10 before we jump into today's episode, I want to share a few ways you can go deeper on your health journey. While I wish I could work with everyone one on one, there just isn't enough time in the day. So I've built several tools to help.
Unknown Speaker
You take control of your health.
Dr. Mark Hyman
If you're looking for guidance, education and community, check out my private membership the Hymenhive for live Q&As, exclusive content and direct connection. For real time lab testing and personalized insights into your biology, visit Function Health. You can also Explore my curated doctor trusted supplements and health products@doctor hyman.com and if you prefer to listen without any breaks, don't forget you can enjoy every episode of this podcast ad free with Hyman plus just open Apple Podcasts and Tap. Try free to start your seven day free trial.
Dr. Gabrielle Lyon
Why is it important to focus on strength training or resistance training or weights or body weights where you have to build muscle? Why is that important? Well, we have a metabolic health crisis. That's why 93% of Americans have a busted metabolism or metabolic dysfunction. Six in 10Americans have one chronic disease and four in 10 have more than one even worse, one in 10Americans have type 2 diabetes and probably one in two have pre diabetes or maybe even more if you're looking at the 93% depending on how you define it. So that's terrifying. 43% of Americans who are adults in here have obesity, which is terrible. That's frightening to me. We also have a diet of too much ultra processed foods, about 60% of our diet. We also have those foods accounting for about 90% of the added sugar in our diet, or about 150 pounds per person of sugar per year. That's a lot of Sugar. Fewer than 23% of Americans are actually meeting the Recommended amount of exercise, which is defined as 150 minutes of moderate or 75 minutes of vigorous exercise per week. Our diet combined with our sedentary lifestyle is absolutely wreaking havoc on our metabolic health. And metabolic dysfunction is the root cause of obesity, of type 2 diabetes, of Alzheimer's, other dementias, fatty liver, kidney disease, and early death. So it's just basically the thing that kills most of us right from cancer, heart disease, diabetes, dementia, kidney disease, many, many other things. Even high blood pressure is caused by this. Now, metabolic dysfunction leads to certain things that go on in your muscle. It becomes filled with fat. It's more like a ribeye than a filet mignon, which you do not want maybe to eat it, it tastes good, but not to have it in your body. Now, intramuscular fat, which is basically what most of us have, it's called being skinny fat if you're not overweight or being overweight with marbled fat. It's really associated with this phenomena of insulin resistance, which is the biggest driver of all age related disease and aging. It's also associated with lower amounts of strength and loss of muscle. We call it sarcopenia, one of the biggest drivers of all diseases and aging, but almost never gets diagnosed. We're going to talk about how to diagnose it, what to do about it. It also drives more inflammation. So the less muscle you have, the more inflammation in your body you have and the more risk for heart disease and many, many other diseases like dementia, cancer, diabetes, all these are inflammatory diseases. It also makes you more tired because your mitochondria aren't working. When you have this problem of insulin resistance in the skeletal muscle, it can often be there decades before you ever see a rise in your blood sugar or get type 2 diabetes. So what if building up lean muscle mass with resistance training could help us avoid this metabolic health crisis? Well, it can. Muscle is more than just about looking good or portraying a fitness aesthetic. It's really a metabolic organ that secretes molecules that promote health or create disease, depending on its health and functionality. There's something called myokines you probably never heard of. Maybe you never heard of them. You've probably heard of cytokines. Cytokine storm from COVID Well, myokines are molecules that help regulate inflammation, and your muscles secrete their own messenger molecules. There's over 600 peptides that have been identified to be secreted by the skeletal muscle. This is huge. These are called myokins. They're messenger molecules that regulate everything in our body and they're released in response to healthy muscle contraction. And the good news is they exert health promoting and metabolism enhancing effects. And they're also anti inflammatory. And that's good for us. Myokines talk to our bones, they talk to our brain, they talk to our fat tissue, they help balance our hormones, our blood sugar, they support our detox system, they help our blood flow and our mental health. Now, many of the protective benefits of exercise in short and long term come from the secretion of myokines. Now, these myokines are particularly effective in the elderly. It's really important because they go down when you get older and you want to build up more of them. So let's talk a little bit about muscle and longevity. I wrote about it in my book Young Forever. It's a really important topic. It's something I actually didn't really want to pay much attention to until I was older. But I bit the bullet. And I've done a whole effort for myself on strength training, which has really transformed my own agility, strength, stability, capacity to do things. And it's quite amazing. I wish I'd gotten into it earlier, but better late than ever. Now, after age 30, you lose as much as 5% of your muscle mass per decade. Most men will lose 30% of their muscle mass in their lifetime. That's a lot. But muscle is the organ of longevity. It's the currency of longevity. Those with lean muscle tend to live longer. Those with more lean muscle tend to live longer. Having and using muscle is one of the most effective ways to slow the whole aging process. Now, what else is exercise good for in strength training? Well, it's good for your brain. Now, one of the things we see a lot in people with Alzheimer's and dementia is sarcopenia and the loss of strength. And that's why in studies, resistance exercise has been shown to improve cognitive function and memory in the elderly with cognitive decline. So what's the mechanism here? How does it actually do this? Well, it boosts something called bdnf. That stands for brain derived neurotrophic factor. It's like miracle growth for the brain. Now, in human studies, resistance Exercise for about 12 weeks to about 6 months has been shown to increase this BDNF, or brain derived neurotrophic factor, and that promotes neuroplasticity, which is the reorganizing, rewiring of your brain's neural networks, which is good connections between brain cells. It also helps stimulate neurogenesis, which is the formation of new nerve cells. So basically, you get new Brain cells and you get better connected brain cells that are smarter. One study found much higher levels of bdnf, even just after one resistance training session. That's not bad. Now it also reduces the expression of pro inflammatory cytokines that are bad for your brain. Uh, exercise also enhances the clearance of something called amyloid beta plaques, which is one of the known pathologies of Alzheimer's. And it, it doesn't just hold up for older folks, right? We don't just want older folks to exercise. Everybody needs to do it. It also works on young people too. A systematic review and meta analysis reported a small but positive effect on the cognitive and academic performance in adolescents who participated in resistance training and association between muscular fitness and academic achievement. So that's pretty interesting. If you're more muscularly fit, you do better in school. Not bad. Same is important for university students. Resistance training is associated with improved attention, concentration, memory with enhanced language and math skills. Not bad. And the way it works is it's regulated by the production of certain neurotransmitters and neuromodulators, things that affect your brain function that are resulting from exercise, like lactate, BDNF, something called IGF1, which is a growth hormone regulator, vascular endothelial growth factor or vegf, which helps your blood vessels stay healthy. Acetylcholine, which is a neurotransmitter, dopamine, epinephrine, serotonin, all these are neurotransmitters. So that's all good. It also increases blood flow in the brain. Now there is something called a healthy user bias, so that may be a factor, but maybe it's the students who do resistance training tend to be more physically active. Maybe they eat healthier, maybe that's why they're doing better in school. Possible, but I guarantee you exercise is having a role. What else is strength training and exercise good for? Well, your mental health. We know that resistance training has antidepressant effects. And research actually tells us that exercise is as more effective than counseling or medication for alleviating depression or anxiety. That's pretty damn good. So better than counseling, which makes you cheaper and better than medications, which often have side effects. In fact, one review published in the British Medical Journal included more than a thousand randomized clinical trials. There are about 120,000 people in those trials. It was the most comprehensive study on mental health and exercise ever done. And what they found was moderate intensity and we call HIIT training, which is high intensity interval training, offered more mental health improvements than lower intensity exercise so workouts weren't long, just 30 minutes daily most days of the week. And I did one this morning was a super high intensity workout with bands and strength training where I also did cardio as part of it because I'm doing it very quickly and you get your heart rate up like mine was, up to 167. All that counts. Now, all types of physical activity were helpful, but resistance training offered the biggest benefit for depression. Now studies report greater self acceptance. They report personal growth flow, state, social affiliations and connections, and autonomy in your life from lifting weights. Not bad. What else is strength training good for? Well, the list goes on and on. It's good for your heart. The American Heart association recently released a scientific statement that resistance training can actually reduce all cause and cardiovascular mortality. It means death from any cause and death from heart disease. Now, when you combine resistance training with aerobic exercise, you get double the benefits. A 40 to 46% reduction in all cause and cardiovascular mortality versus about a 29% benefit from strength training alone, or 18% from cardiovascular exercise alone. Resistance training also improves other factors that relate to cardiovascular health, like blood pressure. It reduces your diabetes risk. It improves your triglycerides and cholesterol. It helps your mood, your body composition, your blood sugar, control, inflammation, sleep, blood vessel health, the quality of your life and overall level of fitness. So it's pretty darn good. And what else is strength training good for? Well, sex. It's good for your sex hormones. Aging beyond 30 to 40 years is associated with a 1 to 3% decline per year in circulating testosterone concentration in men. So as you get older, your testosterone levels drop. If you're a guy. Now, this decline really results in a condition known as andropause, which is just like menopause, but for men. And studies show that immediately after resistance exercise training, your testosterone levels can increase significantly, depending on the intensity and duration of that strength training. The acute spike is temporary, lasts about 30 to 60 minutes after exercise. But over time, resistance training and doing it regularly has increased resting baseline testosterone levels in men, especially when combined with adequate nutrition recovery. And that does a lot of good things for you. It improves your libido and sex drive, your blood flow, sexual performance. So when resistance training is combined with aerobic exercise in a series of trials, men experience a 15% improvement in the erectile dysfunction, which is great. You don't need Viagra. Resistance training helps counteract age related declines in testosterone because it preserves muscle mass and strength as men age. And maintaining lean muscle mass is really important to maintain and sustain Healthy testosterone production, because that's what happens when you exercise your muscle, you make more testosterone. On the other hand, endurance based exercises like steady state cardio don't really increase testosterone levels as much in women. Same thing. Resistance training stimulates the release of testosterone. It also helps increase estrogen, which is important for maintaining bone health for post menopausal women. And it balances the ratio of estrogen, testosterone, and improves insulin sensitivity, which helps a lot of women's health issues like PCOS and irregular menstrual cycles. So in a review on resistance training, women with pcos, which is common and causes infertility, irregular cycles, acne, facial hair, and a lot of things, researchers found that resistance training interventions improved insulin sensitivity in these women, improved their functional strength, and led to fat loss around the belly. We call visceral fat, which is really important for managing pcos because it's really not an ovarian problem, It's a nutritional problem related to insulin resistance. Exercise and strength training is also good for your immune system. Now, resistance training boosts immune function. It helps the body better fight infections. It reduces inflammation throughout your body. So it's great. And it also has been shown to improve the function of various immune cells, such as your natural killer cells, which are roaming around fighting cancer and infections, and your T cells, which enhances your body's ability to fight infections and all sorts of disease diseases. It also boosts your body's production of antioxidant enzymes, your body's own antioxidant system, like superoxide dismutase or sod glutathione peroxidase. These are enzymes your body makes. But when you exercise with strength training, it increases their activity. And by enhancing this antioxidant defenses. Resistance training lowers your oxidative stress levels. It protects your cells, it helps your mitochondria stay protected and helps them from all the damage that can accelerate aging. Okay, so that's a lot of benefits. Your heart, your brain, your mood, sex, pretty much everything. Weight loss, metabolism, it's just kind of a panacea, right? It's amazing. If there was a drug that did all that, it would be a trillion dollar drug, trust me. And yet, you know what? It's available to you anywhere, anytime. All you need is your body weight and you can do it. I mean, you can do other stuff too, but it's easy to get started. So let's talk about how to get started with strength training. You don't have to lift like a bodybuilder to get the benefits. You don't have to be in the gym all day. Studies actually show that people can maintain strength and muscle with as little as 30% of their one rep max, as long as they push themselves to momentary fatigue. So you've got to kind of get your muscles tired. So what is a one rep max? I think of it as a point where you can't do another repetition. With good form, you might be able to get the weight up one or two more times by sacrificing technique and contorting your body, but that's not necessary and it also puts you at risk for injury. So you don't need to worry about the amount of weight you're lifting. That's why bands, light dumbbells, even your body weight can all be effective ways of working out. Now, how much resistance training do you need to do to see results? Well, in terms of minimum effective dose, it's actually not a lot. If you just want to maintain the strength you have. Research shows that just one workout per week, one set per exercise, is going to do the trick. So it's really a minimum viable dose. I don't recommend that low dose, but that's just to maintain where you are. Now, the caveat here is that the one set needs to be all out. So again, you push your muscles to fatigue so you can't do another rep. Or if you did it, it would be bad form. Now, if you're a beginner, you can just do a full body workout plan using all the muscle groups in your body, all the major muscle groups, one day a week. And you can do more. And there's just common, simple exercises, right? Squats, push ups called bent over rows, lunges, planks, dumbbell shoulder press, bicep curls, tricep dips, super simple set of things. You might not need to know everything about how to do them. You can learn on YouTube. You probably want to get someone to show you if you don't know what you're doing, but it's really important. Now, what about maintaining your muscle?
Unknown Speaker
So if you just want to maintain.
Dr. Gabrielle Lyon
Your muscle, you know, basically one day a week for 20, 35 year olds is fine, but as you age, you're gonna need more. It's just the way it goes. That's the bad news about aging. You can stay fit and healthy and strong, but you need to eat more protein and you need to do more exercise, so not less. 60 to 75 year olds will need two workouts a week with two to three sets per exercise. And I encourage people to actually do more, probably Three to four times a week. One day you can do upper body like bench press, bent up a rows, overhead press, bicep curls. One day you can do lower body like squats, deadlifts, lunges, leg press. What about increasing strength and muscle size? If you just want to increase and not maintain. For most people, lifting weights three to four times a week is going to help you significantly increase muscle and strength and give you lots of the health benefits that we talked about associated with resistance training. It's also a good strategy when you're trying to lose weight. Now, some resistance training is better than none. So make sure you set realistic goals that align with your life. Break down bigger goals into smaller parts. Where are you currently? Where do you want to be? What's the best way to get there? Take baby steps and so forth. You know, I, I actually never liked resistance training. I never liked the gym. I thought it was smelly. I was intimidated because I was kind of a skinny guy and I didn't really feel good going to the gym with all the big guys with bald muscles. So I kind of avoided it. But I started doing strength training. I joined a gym, I got a trainer, I learned the basic mechanics. I worked then with bands, especially during COVID and I got really strong just doing three to four days a week at home. It took me 30 minutes in and out. Really simple. And I didn't have enough to drive the gym. So I think encourage you to learn how to do this. It's critical and there's just so many resources out there. There's just no excuse. So how do you make resistance training work with your schedule? Well, I travel a lot. I bring my bands with me everywhere. They're basically a pound or less this big and I bunch them up and they spit in my suitcase. Even a day carry on or a light suitcase. You can use body weight workouts, planks, squats, push ups, and also block out the time that works for you. Even if it's only 15 minutes broken up into 5 minute chunks throughout the day. Just do something right. Maybe you look at your roadblocks, work your kids, schedule events, holidays, you know, I want to start doing pushups and I, you know, just was busy and I just didn't like exercise. And I like, okay, I'm gonna, I'm gonna take a, every day I take a shower and I, and I usually takes a minute for the shower to heat up my house. So I have like a couple minutes while it's warming up. And in those couple minutes I would get on the floor And I would do pushups, as many as I could possibly do. And that was great. And it really helped me get into the strength training at a very low friction level. Or I would do tricep dips just in my bathroom on the bench. So really simple stuff to get started. So just make sure you do a commitment to yourself and hold yourself accountable. Do something right? A fast paced walk around the neighborhood with weights on your body. Just do 15 pushups, 25 air squats, something. Just do something. Okay, now what else do you need to do to build muscle? Strength training for sure. And 75% of our muscle mass is related to strength training. But the other 25%, and this is a key 25%, comes from our diet. Now we need to make sure we're eating enough protein to build muscle back up. You need to eat muscle to build muscle. It's just how it goes. It contains all the building blocks to build muscle. You can get plant protein, but you have to supplement it with amino acids that you find in animal protein in order to act the right combination to build muscle. And turn on the muscle building switch or what we call muscle protein synthesis. And you need about 1 gram per pound of ideal body weight. If you're trying to build muscle, you can do 0.7 if you're already there and maybe you don't need as much. But basically 0.7 to 1 gram per pound of ideal body weight is what you want to do. If you don't like working out of the gym, which I don't really like, try other things you can do. Rucking. It's probably the best exercise most people don't know about. That's putting a backpack on with weights. It add loads for your muscles and bones, increases demand on your heart for a brisk walk. So it's great and it's been shown to be helpful for back health. And it doesn't require a lot of special skills. You just get a weighted vest or something that actually maybe is better. You can throw weights in a backpack that can be a little hard on your body sometimes and just go for a hike somewhere where there's mountains or hills. Yoga also can be helpful. I, I did a lot of yoga for my life. I didn't find it to build a lot of muscle, but I, if you're, you know, really aggressive with it, I think you can. Now does all this sound too intimidating? Maybe you don't have time in your schedule. Maybe you can try exercise snacks. Now, what are exercise snacks? Well, exercise snacks are isolated bouts of vigorous exercising Lasting about less than a minute. And they're performed periodically throughout the day. Just like snacking, right? But this is a good kind of snack exercise snacks can help offset the effects of sitting all day. Now the feasibility and time efficiency of exercise snacks makes them really suitable for incorporating between activities of daily life, right? And it leaves at the need for planning and adequately all kinds of leisure time for structured exercise. So every hour, maybe have 10 to 20 air squats, stand at your desk, get your heart rate up by going for a brisk walk, take the stairs, bring resistance bands to your office, you.
Unknown Speaker
Know, do all those things.
Dr. Gabrielle Lyon
It's all possible to incorporate into your life.
Dr. Mark Hyman
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Unknown Speaker
I have individuals that I see them go to the gym and I watch them train. I know that they're not training in a capacity that they need to be. Even though they're doing fun stuff like ropes and battle ropes and they're trying to jump on a Bosu ball and all of these fancy feel athletic type things. But at the end of the day, they're not able to generate enough power, they're not able to generate enough force, they're not focused on strength and, or hypertrophy. Strength is obvious. Hypertrophy is muscle growth. I would argue that if you focus on muscle growth, you're going to get stronger, you're going to get more force, you're going to get more power, you're going to be able to do these things. And he said, gabrielle, think about high ground activity. I'M like that. What the heck is high ground activity?
Right?
He said, when you're on a mountain. Exactly. I'm like, are there Sherpas here? What are we doing? I don't know what high ground is. And he said, focusing on muscle hypertrophy is the most important thing. If they build and target the growth of healthy skeletal muscle, they will get stronger, they'll have better metabolic control, they will have a better ability to generate more of a VO2 Max. They'll be able to do everything better and go back to the basics. And so high ground activity. And people are going to be like, I didn't think we should use. Machines are high ground is exactly that. Lots of contact. For example, a hack squat. A hack squat is a squat that has a backrest. Your feet are on something, your legs are. Your arms are touching something. It's a lot of contact and a lot of feedback. So when you are able to engage in that exercise, you are fully focused on the muscle of choice. And by choosing those type of things, and that is what we consider a compound movement, you are putting in effort in the right place as opposed to going and doing bicep curls, which would be considered a low ground activity. You are not supported. Maybe you're standing up, maybe you're swinging your arms, maybe you're. Instead of working your.
It's better to use these big machines.
Dr. Gabrielle Lyon
Is what you're saying.
Unknown Speaker
Yes. And it's called high ground training.
So you need to.
I need to buy these expensive machines.
Go to the gym.
But think about has to matter enough. Could you do resistance training, body weight and bands and all of those things? Absolutely. Do we need to do that? Totally. But if we are really serious about our health and wellness, we have to put some effort in to do those things. And I get a lot of pushback when people say, well, do I have to go to the gym? No, you don't have to. If you're certainly more advanced and you know that you can move and do things in a way that is safe. Because here's the reality.
I should get a trainer, go to the gym. So you.
Yes, until you learn how to do it myself. Until you. And another high ground activity. So people think about lunges or split squats. So that's one leg in front, one leg in back. But another way to do that would be one leg in front and then have your foot back up against a block. So now you've got.
Why does that work better?
Because now you've got your foot fully flat instead of a split Squat in the way that you're doing it or like an assisted deadlift where a single leg rdl, basically what I'm saying, Russian deadlift. What I'm saying is when you increase contact, you are now training the muscle with the intensity. Again, intensity declines as we age. It doesn't have to be heavy. You do have to go to a level of fatigue because you're looking for stimulants.
Dr. Gabrielle Lyon
And what about these other kind of.
Unknown Speaker
Tools for people who, who have injuries or who, you know, sort of their hacks to get the intensity without the injury or hurting yourself like electrical stim exercising or a blood flow restriction or these vasper cooler kind of things.
Wonderful.
How effective are those?
Because I mean, I'd rather probably like at my age get a bunch of blood flow restriction devices or electrical stims so I don't have to hurt myself because I have a bad back and I don't want to hurt myself. So is that as effective?
I can't say. You know, I haven't seen any data. You know, this is very difficult to do over time. You can't. It's very difficult to follow someone and control for everything. You know, I've worked with a lot of special operations community. They use a ton of blood flow restriction and injury. I know a lot of physical therapists that use it. Individuals use it to help with rehabilitation. Slowly loading up tendons. Again, it's not always muscle injury. It can sometimes be tendons, it can sometimes be ligaments. How do we go in a slow, progressive way to eliminate the potential for injury? So, yes. Do I think a stim suit is great? I do. Do I think blood flow restriction is great? Absolutely. Do I.
Does that allow you to do the intensity without that?
It does.
Risk of incident.
The stim suit is. It's different. It's different because it's.
When you get the muscle hypertrophy and.
The growth, you will. I mean, again, I'm saying that as if I know everything about it. I'm assuming. Yes. I've seen some data to support. Yes. I've also seen rhabdo from it, which.
Means damage to muscles. Yeah. From electrical stimulation, from electrical stem. But you also get that from just training. I've seen people with high muscle enzymes after training.
Yeah, absolutely.
Dr. Gabrielle Lyon
Yeah.
Unknown Speaker
I think that the real magic is going to be the interface with fitness professionals and medical professionals. The true interface. Because we can't do what we do without that component. You know, and I have. There's.
That's why, you know, I don't know if you know this with Function Health. Right. Which I co founded to be able to test all your biomarkers. We partner with Equinox because I didn't know that.
Where was my invitation? How come I, like, get it later. What is that?
Dr. Gabrielle Lyon
It just got announced. But, you know, there's a membership and.
Unknown Speaker
There'S a whole thing. But the idea is that, you know, you need to look under the hood and deal with the medical aspects, not just the training aspects too.
Yes, I fully agree with that. And then I think that the other thing is that people feel like strength training, resistance training is interchangeable, that they could go do a class or do something else. And I would say there's nothing more important, from my perspective as a geriatrician than strength training, to really focus on resistance exercise, everything else. I love the idea of having a great VO2 max cardio, which is cardiovascular activity. Here's how I prefer someone do it. Do high intensity interval training to compress the time. Because sometimes people can't manage the length of time it takes and the effect on joints or even the interest. You should do things.
So how long, just practically, as we wrap up practically.
How much time a week should people devote to strength training?
The more intense an individual works, the less time it takes.
So you could do once a week, super intense.
I wouldn't recommend it. I don't think that's optimal.
Dr. Gabrielle Lyon
Twice a week, three times a week.
Unknown Speaker
If I were to design a new lifter or even advanced lifter, I consider myself an advanced lifter. I train three days a week and.
20 minutes, 30 minutes, 45 minutes.
A shout out to Carlos Mata, my trainer. You should come in and get some push ups with us. But seriously, full body, three days a week, very intense. We do push, pull, hinge. Those are all actions. Someone could look that up. We do sled pushes. We do things that are dynamic, hard, that continuously challenge me. But for a beginner, they are going to get the biggest bang for their buck. They're going to improve the most.
Yeah, yeah, I saw that. It was amazing, actually, what happened.
Three days a week, two days a week, full body. It's not about the time, because you could go there and you could be on your phone.
It's about the intensity.
It is about the overall volume, the overall amount of work that you're doing.
You do lighter weights, more reps.
Exactly.
So that can be considered intensity.
It could be as long as you're going close to failure, you know, and I never believed that until I started seeing this stuff out of McMaster. University. I was like, no, you gotta lift heavy, but you don't. Two days a week, full body. Ideally, that's enough to maintain. If you were Gonna, you know, five to, I don't know, pick a number. 25 reps. Again, it's. There's so many different ways to do it right, which is amazing.
Yeah.
The only one way to do it wrong is to not do it.
Yeah, that's a good line. The only way to do it wrong.
Is to not do it.
Hear that out there.
Dr. Gabrielle Lyon
Because I was a late starter and.
Unknown Speaker
I regret not doing this. When I was younger, I really regret.
I tried, I tried.
I know I was bad.
I mean, at least 10 years ago, I was like, mark, you cannot be doing all this yoga. Yoga is wonderful. But come on.
Yeah, yeah, I know.
And by the way, it is wonderful.
Dr. Gabrielle Lyon
So let's talk about the.
Unknown Speaker
Now that we've talked about the need for training and the amount and all the different varieties of kinds of things we can do. And by the way, all of this is in your book Forever Strong, so people can check that out. And check out your website, which is drgabriellion.com my YouTube.
I have training programs, training programs. Check out stuff that I do.
Definitely follow this lady. She's amazing. And she's going places.
You better be.
It's like that Dr. Seuss book.
Oh, the places you'll go.
That's her.
I'm going to the gym after this.
I'm going to the gym.
Okay, well, I'm going to a concert.
Are you really?
Dr. Gabrielle Lyon
Yeah.
Unknown Speaker
Grateful Dead.
There you go. And the next piece, I want to.
Talk about, and we talked about this.
When you were on last time, quite a bit about protein and about diet and about diet and muscle. And I think your perspective has changed over time. We're learning things over time.
And I think the question is really.
When, what, and how should you be eating to optimize your muscle health?
Great question. Probably my favorite topic, although I think that I might eventually, I don't know, talk about underwater basket weaving. God, I killed that joke. But in the meantime, protein is the most controversial macronutrient. It just is that way. And I think that it is, and it will continue to be that way. But what is the reality of why we need dietary protein? Why we need dietary protein? Because we need these amino acids. We often only hear people talk about protein as the building blocks. I would say let's scrap that and let's talk about dietary protein. When it comes to each of these essential individual amino acids do different Metabolic things in the body, they are not interchangeable. I'll just give you a few examples. Threonine is an essential amino acid for mucin production in your gut. I remember some of the first patients I saw with you, they all had, quote, leaky gut. Threonine for mucin production, arginine for nitric oxide production, which is to dilate your blood vessels inflammation. Right. You know, tryptophan for serotonin production for your brain, leucine for skeletal muscle stimulation. As you can see, they all do different things. They're not interchangeable. So then the next question is, well, that's confusing. How do I eat for that? I would say you're right, that does sound super confusing.
Thank God nature took care of it for us.
They did. First, most important thing that someone understands is how much protein that they are getting. And that trumps everything. If I were to say, what is the protein hierarchy? That would be 1.6 grams per kilogram, which is 0.7 grams per pound.
Ideal body weight, which is double what the RDA is. The rda, which is the minimum amount you need not to get a deficiency disease.
And that's 0.37 grams per pound or.
0.8 grams per kilo.
Exactly. Which is also based on only high quality proteins.
Yeah.
So that's not based on plant proteins.
Not based on plant. And you're saying plant proteins are not.
High quality proteins based on the definition from digestibility and amino acid profiles. It's just, you know, people get very offended by that. It is purely biological numbers. It's not, this is better, this is worse. This is purely based on the spectrum of amino acids. So the first most important thing is getting enough protein. And people will say, well, we get a ton of protein. Well, we get a ton of protein. For what do we get a ton of protein to overcome the minimum deficiency? Yes. But do we have enough protein with an appropriate amount of calories to maintain healthy aging and metabolic correction? And I would say we have some work to do. The average individual, the average male, gets about maybe 90 to 100 grams of protein. Average female is probably around 70 grams of protein. And we know that in order to protect skeletal muscle, that we're really looking at closer to 1.6 grams per kilogram. So 0.7 grams per pound or closer to 1 gram per pound. Ideal body weight.
If I'm 180 pounds, you're talking about 150 grams of protein a day.
That's reasonable. Now that's the first most important aspect Whether it's coming from plants or animals, if you choose to. And this is just protein. This is not talking about where you're getting your iron or creatine or B12. We're purely talking about protein, not the other micro nutrients that are diminishing. And we have deficiencies of like none of that.
And that are different in animal versus plant protein.
Plant protein has a lot of fiber and phytonutrients and lower protein quality. If someone wants to get their protein from plants, they are likely going to need a certain percentage more depending on the source. Maybe it's 30% more. Overall calorie consumption is going to go up. But you can get enough of these amino acids necessary for muscle health. However, you have to be careful. If you are older and you are not highly active, then if your idea is to eat whole foods and eat whole foods from plant based proteins, then you have to watch total calories and carbohydrates.
Yeah. I mean, could you, you know, if you want to get, you know, 4 ounces of chicken is a few hundred calories and the equivalent of that in quinoa is like six cups, which has got like 1,000 calories.
Correct.
So how do you manage that?
Dr. Gabrielle Lyon
Right.
Unknown Speaker
And the way in which you manage it is you choose things like tofu or rice pea blend protein powder.
So you have to eat processed proteins in order to actually maintain the level of protein you need as you get older, Is that what you're saying?
I would say straight from very active. So unless someone was very active, then I would be concerned about the ability to dispose of the carbohydrates and overall calories. I would have certainly concerns about that just from a metabolic perspective.
So basically if you're like run five miles a day and you do all this stuff and then you eat more calories, it's fine. But if you're just an average person who's not doing that and you're trying to build muscle, the amount of protein you need is going to kind of put you over the calorie limit and end up causing metabolic issues.
I mean, it definitely depends. There's many ways to do it well, but what I would say is that understanding that the total protein intake is most important, understanding that that first meal of the day is critical because you're coming out of an overnight fast. There's only two ways to stimulate skeletal muscle and you have to protect it, and that is through resistance training and dietary protein. We know that when you are in an overnight fast, you are catabolic. The body is using liver glycogen and potentially pulling from amino acids from skeletal muscle. Because these processes protein turnover throughout the whole body has to be going on.
Dr. Gabrielle Lyon
Yeah.
Unknown Speaker
You can't, like, your body stop, like repairing tissues and making new cells and proteins all night long. It still has to do that. And you do that in a state by using kind of recycling proteins. That's called autopathy. It's a good thing.
You recycle proteins. You recycle an enormous amount of proteins, you oxidize, you replace. It is a very dynamic process. Understanding that that first meal of the day is most important. I don't care when you have it. But coming out of an overnight fast.
So we should be having like, what, French toast, a muffin if you want a completely Starbucks Matcha frappolata Mochacino.
Yes, exactly. But the evidence is very interesting from a satiety standpoint. So there's a skeletal muscle standpoint. You want to hit between 30 and 50 grams in the morning when you wake up. And that's also the same amount.
So it's kind of the opposite of.
What we do in America is we don't eat protein for breakfast, we eat sugar for breakfast.
Right. You know, I worked on some of these early studies, and one of the. It was two groups, and one of the groups, they followed the food guide pyramid, which was 55% carbohydrates, the RDA of protein, and 30% fat. And they were both isocaloric. And then the other group was roughly 40 grams of protein at breakfast. It was a 40, 30, 30 split, like the zone diet. So 40. Yeah. Well, anyway, it was 40, 30, 30 split. And what we saw was that those that were isocaloric but just adjusted the macronutrients. The macronutrients actually lost body fat, maintained lean tissue, and with exercise, there was this fantastic synergistic effect that the majority of weight that they lost was fat.
So basically eating.
Just to put that in English, basically eating protein in the morning, reducing starches and carbs, combined with exercise got the most benefit. Even eating the same exact amount of calories.
Yes.
Right.
That's amazing. So you switch from the standard American eating trajectory to a more balanced distribution. And this is kind of where we don't have time to talk about this one. But this is kind of where that whole 30 grams of protein three times a day came in. There's actually no evidence to support that.
So does it matter? Like, you get.
You're saying, like, I need 150 grams of protein. Could I have like a 900 gram ribeye steak and that like. And that gets me going for the whole day.
If I could probably do 70, I mean, I wouldn't suggest that because then you're stimulating tissue once a day and we've seen that. So there was some.
Did you want it more evenly spread out or like just. Does you have to do it before exercise? Does it matter?
Dr. Gabrielle Lyon
It matters after exercise.
Unknown Speaker
How long after exercise?
Great question.
People need to know the practicalities of how do you apply this to get the most benefit?
Dr. Gabrielle Lyon
Because there's a lot of science behind this.
Unknown Speaker
There is. If you are young and healthy, it really doesn't matter. As long as you're hitting your total protein target, it doesn't matter. I don't care when you get your protein, I don't really care what kind you get your protein.
So you can have cereal for breaks when your kid and be fine.
I mean, I don't mind, but my kids don't. But it doesn't really matter as long as you're getting your total protein intake in. I don't care if you have it around exercise. I don't, frankly, I don't care.
That's because there's a lot of hormonal activity as you're younger that drives growth.
Your tissue is highly anabolic. If you are more mature, if you have weight to lose, if you have underlying inflammation, then understanding first the total amount of protein is critical. Recognizing that that first meal of the day, which is where all the data's been, all the data is from, to my knowledge, is on that first meal of the day. Again, I worked on some of these early studies and what we saw was changes in body composition with carbohydrates managed. That first meal of the day is critical. The second meal of the day I don't really care about. It's just to get in that protein. And there should be some kind of a one to one ratio of carbohydrates to protein. You don't want to overshoot your carbohydrates for no reason. And then arguably one could consider that last minute of the day being very important because now you're going into an overnight fast.
So what should that be?
Same thing, between 30 and 55 grams. But here's the thing.
If you are protein also makes you feel full and it also takes more energy to burn protein in the body.
It stimulates muscle protein synthesis, which is a. This is where the thermic effect of food comes in. Thermic effect of feeding. So fats, maybe 3% of the calories from fats are utilized for the utilization of fatty acids. Carbohydrates might be.
It takes energy to metabolize fat.
10% protein can be 20%.
So you eat 100 calories of protein. 25 of those calories are 20 goes into actually processing and metabolizing and breaking down and burning those calories.
I actually believe.
So the net net calories less is what you're saying.
Yes. And I believe that it's actually from the stimulation of muscle tissue and not the disposal of urea or nitrogen, which are the byproducts of protein. It is from the leucine stimulation of muscle. But what's. Let's let me close out with some very practical things. If you are young, I don't care what you're doing, you can have 5 grams of protein in the morning. In the afternoon doesn't matter as long as you're getting your total protein in.
Yeah.
If you are older and let's define older, inactive, have weight to lose or under protein, you are protein deficient or you're eating a sub amount, then understanding that total amount of protein matters. First. Let's just shoot a high 1 gram per pound ideal body weight. But the evidence is perfectly fine with 1.6 grams per kilogram or 0.7 grams per pound body weight. You're going to ask me what is your ideal body weight? Pick the last time you felt great. This is human science, which is not a perfect science. Then the first meal of the day should be between 30 grams. Could be higher if you wanted to eat twice a day. Let's say you needed 75 grams at that first meal. I don't care. Go right ahead. I just want to make sure that you're really hitting between 30 and 50. Now. Does it matter that it's around exercise? Not for exercise.
That's what I do.
I notice when I do my morning goat whey protein shake, which is my healthy aging shake that I wrote about in my book Young Forever. And I'm working out at home and I have my routine. It's amazing to see the gains I have in muscle very quickly.
Let's talk about why that is. This is one of the nuances that if you look at the International Society for Sports Nutrition, they will say it doesn't matter when you eat protein. And I would say I appreciate that. Especially if someone is young and healthy. When you are more mature, Mark, you're more mature.
Dr. Gabrielle Lyon
Thank you.
Unknown Speaker
We have to overcome anabolic resistance. How do we make your skeletal muscle respond like younger skeletal muscle? You do that by resistance training and the synergistic influence of also the amino acids, the protein with the protein and the strength training. If you look at the data, it looks like this is. You've seen this in Bob Wolf's lab, you've seen this in Kitsano's lab. Your muscle responds exactly like youthful muscle. So you wouldn't be able to tell the difference from a metabolic perspective. If someone is listening and they're like, well, should I train fasted? Go right ahead. But now, after you've done, you're done training and you want to take advantage of blood flow, give yourself 30 minutes and within that 30 minutes to an hour. Because now your muscle is primed to receive nutrients, have your protein can't be right after.
Sure, of course, you don't have to wait 30 minutes.
No.
But you shouldn't wait three hours if.
You are young and healthy. I don't care.
I'm talking about me. I don't care about all those young people.
For you, no, but for you, if we wanted to.
My joke is, everybody's favorite radio station is wifm. What's in it for me?
Dr. Gabrielle Lyon
Asking for a friend.
Unknown Speaker
Asking for a friend. Then for you, I would say that that would be a benefit. If someone wants to lose weight, if they have low grade chronic inflammation, this is a great way to help get nutrients to the muscle. That second meal I don't care so much about. Could it be 30 to 50 grams of protein? Sure. Does it have to be an even distribution? No. Could it be 20 grams of protein easily that last meal of the day? I like making sure that there's two meals that are robust in protein. Because now you're stimulating that tissue going into an overnight fast. Is there evidence to support that that meal is the key to metabolism? No.
Well, you shouldn't eat late, that's for sure.
Well, it'll affect, it'll affect your sleep.
It'Ll cause you to gain weight.
Now, I'm going to leave you with one more thing.
Dr. Gabrielle Lyon
Yeah.
Unknown Speaker
Because I think this is really important.
Okay.
And that is if you fail to do the practical, the practical becomes impossible.
You know, what does protein do? Well, why do we need so much of it? Well, it's an essential nutrient because it's the stuff we're made of, right? We make proteins. That's all your DNA does. The DNA is very simple. It basically transcribes the sequence of amino acids that are needed to build a particular protein. That's all your DNA does. So it assembles amino acids to proteins. Proteins are the Structural material for your body, muscle, bone, you know, pretty much everything your immune system is made from protein. For example, the antibodies, your peptides are made which are these thousands of cellular communication molecules. It's critical that we eat adequate amounts of protein. It's also the most essential thing. We need to build and maintain muscle and prevent muscle loss. And as you know, I've been very focused on longevity. Of course I'm going to be 64 this year, so I get more and more interested in as the time goes by. And you need adequate types of the right protein to make sure you don't get. We call sarcopenia, which is muscle loss and that is one of the biggest drivers of age related disease. And we're going to talk more about that. So you need to optimize your nutrition, you need to make sure you're eating the right amount for you. And you need to make sure that we understand protein and get out of the weeds of the ideological view and talk about the science. So today we're going to talk about the science. We're going to talk about how to up your protein intake. We're going to talk about, you know, why the guidelines for protein intake are wrong and confusing for people and even give you a delicious smoothie, protein rich smoothie that you can use, that I often use to start my day. All right, so we've known for years and decades that protein is a critical part of our diet because they're basically the building blocks for our body. It makes everything from muscles, organs, our skin, neurotransmitters, cytokines, peptides, all the things that our body is doing to actually run everything. It's, it's really one of the most essential things because we can't get all the amino acids from, you know, eating other foods. We have to eat the protein in the right amounts and we have to have the right amount of amino acids. Our body doesn't make, make them, some are derivatives. So there's some core essential amino acids and we have to make sure we get them from our diet in the right amounts in the, in the right time. And, and when we look at the research on longevity, there's a lot of controversy. Some people say, oh, don't eat protein because it's gonna actually activate MTOR or what is the known as, as the, one of the key regulators of longevity. If you activate mtor, it increase protein synthesis, it increases muscle mass, it can actually accelerate even cancer growth. So it's not good in, in, in certain ways. But if you inhibit mtor, you actually cause autophagy and self cleaning and the longevity process. So what should you do? Well, I wrote a lot about, it's like anything else. You want periods of fasting and not eating, like overnight, at least 12, 14, 16 hours. And then you want to make sure you have enough protein during the day so you actually can do the functions of protein in your body, for example, muscle building and so forth. So we, you know, it's not, it's not like it's all bad or all good. It's, it's really about how and when and what. So we're going to get into the how and when and what. And if you, if you look at the biggest risk factor for, for age related decline, it's, it's loss of muscle. Because when you lose muscle, you increase inflammation, you increase insulin resistance, your sex hormones go down, your cortisol goes down, your growth hormone goes down. I mean, cortisol goes up. I mean, so you basically end up in this hormonal chaos of levels of inflammation, prediabetes, it's, it's really bad. Now let's talk about how it affects our appetite, our metabolism and so forth and why it's important. So, so we're going to talk about a little bit more about why protein matters. But in, in terms of, of hunger, when you eat protein, it actually inhibits ghrelin and increases the production of a hormone called peptide, yyy, or pyy, which is a gut hormone or peptide that makes you feel full and satisfied. Right? So higher, higher amounts of protein can decrease the ghrelin, which is the hunger hormone. It also increases your metabolic rate. There's something called the thermogenic effect of protein. You basically, you know, takes more energy to break down protein, so you burn more calories metabolizing protein. So in a way, even though you're eating let's say 100 calories of sugar, maybe it takes like three calories to, to actually metabolize it. Whereas protein, it might take 20 calories to metabolize. So your net net calories is lower when you're having protein. So it's been linked to weight loss. Also, having protein in each meal provides, you know, a way to regulate your appetite, helps with weight management, helps with maintaining muscle mass because often people lose both muscle and fat when they lose weight. And then you end up having a slower metabolism, which people say, oh geez, I don't know why I lost weight and I have to eat less because if I eat a little more I gain weight. Or people who are overweight say, I don't really eat that much. And sometimes that's true because they've lost so much muscle, their metabolism is so slow that they can't burn the calories. So the protein, it's, it's critical. And your, your muscle burns a lot of calories, actually burns about seven times as much calories as fat. So the more muscle you have, the more calories you burn, the easier it is to maintain your weight. Meta analysis, for example, in 2020, found that a high protein diet can increase weight loss and help the weight stay off and prevent obesity and various related diseases. So that's really important. Also, you know, the requirements that the government has the Recommended Dietary Allowance or RDA or rdi, Reference Dietary Intakes, they change the terminology all the time. But essentially we're told that we need about 0.8 grams per kilo of protein. Now how do they come up with that number? Well, that number is based on how much protein do you need to not get a deficiency disease. In other words, how much protein need to not get quashior core or marasmus, which are these protein deficiency diseases. And that's not that much.
Dr. Gabrielle Lyon
Right.
Unknown Speaker
So it's not the amount we need for optimal health. And people go, oh, I don't eat more than 0.8 grams per kilo. Well, no, that's the floor for most people. So what do we actually need? Depends on your activity level, how much strength training you do, your life goals, and your age. But as we age, we don't actually build muscle as easily. We have something called anabolic resistance. So we actually need more protein as we get older. I tell a story, my book about Emma Morano, My book, Young forever. She was 117 years old when she died. When she was in her 90s, she was starting to get frail and her doctor told her to eat, I think, 150 grams of meat a day, which sounds like a lot, but it actually not as much as you think. And she was fine and she got strong again and she ended up living to 117 years old. So I think we have to kind of look at that and go, wake up maybe, maybe they're onto something. So the amount we need is probably more like up to a gram per pound or 1.6 or even up to 2 grams per kilo in a day. And that may seem like a lot, but there's a way to do it. And it's not as much as we think. For example, you know, a small, you know, chicken breast, like 4 ounces, which is not that much, it's probably like half of what people normally eat is, is actually 40 grams of protein, almost 40 grams of protein. So that, that's important to understand. You don't have to have huge amounts of, of steaks or meat or anything like that. It's really relatively small amounts that gives you a big bang for your buck. Now here's, here's another really important point. Quality matters. Not all protein is the same, just as not all fat is the same or carbs are the same. Broccoli is a carb, but so is Coca Cola. Trans fat or Crisco is fat and so is omega 3 fats. But they have profoundly or olive oil. They profoundly different effects on the body. Same thing with protein. Not all protein is equal. Now part of the problem is right now I think people think that eating meat is bad for your health and bad for the planet. And I've written a lot about this, I've talked a lot about it. I think it's a complicated subject, but from a health perspective, the data just isn't there to show that meat is bad for your health. It really is not. When you look at these population studies, they're confounded. There's problems with them. And there's been a lot of reviews of this. I go into it in depth in a number of my books, including Food what the Heck Should I Eat and the Pegan Diet. You want to read more about it, we'll link to those. But I think it's a whole nother.
Dr. Gabrielle Lyon
Podcast to get into that conversation.
Unknown Speaker
But the reality is that when you, for example, look at meat eaters and vegetarians who shop in health food stores, they did a study of 11,000 thousand people. They found that their risk for death was reduced in half for both groups. It's not the meat, it's what you're eating it with. If you're having, you know, hamburger, fries and a Coke, it's different than having, you know, a grass fed piece of meat with tons of veggies. For example, when I have a grass fed steak or regeneratively steak, I'll. I'll have like three or four different vegetable dishes. So I have a lot of phytochemicals. I don't eat a ton of sugar.
Dr. Gabrielle Lyon
And starch with it.
Unknown Speaker
And it's a very different kind of approach. Now industrial meat is not good. So we should not be eating feedlot meat. We should not be eating industrial agricultural products. And you know, when you have industrial meat, it's got hormones, antibiotics, they feed it, you know, grain and soy and so forth. They're not used to their diet and they get different types of fats and more inflammatory process. But grass fed meat is far superior and so is regenerative meat. Regenerative is way better. And there's a company called Force of Nature which you can go on forceofnature.com I don't have any financial ties to them, but they're, they're great resource for finding regeneratively raised meat from around the world that actually is delicious. Whether it's venison, bison, beef, and it's, it's amazing because they're raised in their natural environments. They have higher levels of omega 3 fats, they have higher levels of minerals, higher levels of antioxidants and it's powerful. So also if you're eating fish and you want to eat fish, yeah, I know wild caught fish can be great. But there's also regenera fish that can be regeneratively farmed, which again is unusual, but fish is delicious. Another company called Seatopia Fish, we'll put that in the show notes. Again, no relationship to them, but I just love their products. And, and here, here's the other part about protein. You know, if you're vegan, it's problematic because not all protein has the same types of amino acids. And one of the things in, in, in building protein in your body that's so important in activating muscle synthesis and protein synthesis for muscle is an amino acid called leucine. And leucine is very low in plant proteins. Now you can get enough, but you have to eat a lot. In other words, to eat to get enough of the same. You get, for example, in 4 ounces of chicken, you'd need like 2 cups of beans or 6 cups of rice or fruit, 4 cups of quinoa. It's a lot, so you can't really eat that much. It's very tough to get the right amounts of leucine unless you supplement. Now if you want to be a vegan and you're committed to that, you have to optimize your health by adding certain amino acids. And you can do that. You can make smoothies, you can put in branch chain amino acids, you can, you know, have, make sure you have the leucine you need. It's doable, but it's a lot harder. And you, you see often as, as people stay on a vegan diet, they tend to have muscle loss and that's, that's a big concern, particularly as we age. So make sure you're Getting you know, plenty of the right kinds of protein. You're supplementing with amino acids and, and consider you know, maybe even becoming a vegetarian and having grass fed goat whey for example which is a really great source of protein which I use. So let's talk about how we can get more, more protein diet. What's. What are a few ways to get more protein? Well, it's not hard if you actually know what you're doing. You have a plan, you think about it. First is and this is a really important thing, you want to get at least 30 to 40 grams of protein per meal. And usually you know, you can think about for your size. The palm size of a piece of protein is probably what you need. So I'm six three, 180 pounds. It's different than if some five, two and you know, 110 pounds. Right. So we need different amounts depending on our size. But basically whatever your size of your palm is really a good amount. And you can focus on things like 4 ounces of chicken for ounce of meat. You know, probably more like 6 ounces of fish because the lower and you can use whey protein. I like goat way really is a powerful whey protein that doesn't have as much allergenic properties. Or you can get regeneratively raised grass fed goat whey a two cows a little harder to find. So basically you want to make sure you get adequate protein. Now it can be any of those things I just mentioned. For example, for lunch I grab some a can or two of sardines. It's really easy, it doesn't have to be that hard. The other thing is when you eat what for example, if, if you eat sugar and starch at the beginning of your meal. For example, you go to a restaurant, they give you bread basket and wine. Worst thing you could possibly do. You want to eat protein and fat before you eat starch and any carbohydrates because it blunts the effect of the absorption and insulin secretion which leads to sort of less weight gain and more, more feeling full and so forth. So you want to make sure you start with, with protein in your meal. And then the last thing is, you know, we have the worst breakfast in America and the most important time to eat protein is on a fasted state. So it's not just the fasting that works to help your body, right? When you, when you have this overnight fast of you know, 12, 14, 16 hours, you, you activate something called autophagy which is process of self cleaning and repair. But what matters also is what you eat after, right? If you have the typical American breakfast, which is basically sugar for breakfast, cereal, muffins, bagels, pancakes, and I could go on and on, you know, Pop tarts even. I used to eat pop Tarts for breakfast as a kid. It's amazing I'm still as healthy as I am. You want to not eat sugar for breakfast, you want to have protein for breakfast and, and, and you want a good load of protein. And when you refeed is when you activate muscle synthesis, activate stem cell production, produce all sorts of important benefits that are downstream from eating protein in the morning. So make sure you have at least 30, 40, even 50 grams, depending on your size of protein in the morning.
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Podcast Summary: The Importance of Weight Training, Protein, and Muscle
Podcast Information:
In this episode of The Dr. Hyman Show, Dr. Mark Hyman is joined by Dr. Gabrielle Lyon to delve deep into the critical roles that weight training, protein intake, and muscle mass play in overall health and longevity. The conversation addresses the alarming rates of muscle loss, the metabolic health crisis in America, and provides actionable insights on incorporating strength training and optimized protein consumption into daily life.
Dr. Gabrielle Lyon begins by highlighting the severity of metabolic dysfunction in the United States:
Muscle Mass Decline:
"After age 30, you lose as much as 5% of your muscle mass per decade. Most men will lose 30% of their muscle mass in their lifetime, but muscle is the organ of longevity."
(00:02)
Prevalence of Metabolic Disorders:
"93% of Americans have a busted metabolism or metabolic dysfunction. Six in 10 Americans have one chronic disease and four in 10 have more than one. One in 10 Americans have type 2 diabetes and probably one in two have prediabetes or maybe even more."
(01:21)
Diet and Lifestyle Factors:
Dr. Lyon explains the consequences of muscle loss, or sarcopenia:
Intramuscular Fat:
"Intramuscular fat... is associated with insulin resistance, which is the biggest driver of all age-related disease and aging."
(01:21)
Health Risks:
Metabolic dysfunction from muscle loss leads to:
Dr. Lyon emphasizes resistance training as a pivotal solution to the metabolic health crisis:
Muscle as a Metabolic Organ:
"Muscle is more than just about looking good; it's a metabolic organ that secretes molecules that promote health or create disease, depending on its health and functionality."
(01:21)
Myokines:
"Myokines are molecules that help regulate inflammation, and your muscles secrete their own messenger molecules. They regulate everything in our body and exert health-promoting and metabolism-enhancing effects."
(01:21)
Myokines influence:
Muscle and Lifespan:
"Muscle is the currency of longevity. Those with lean muscle tend to live longer."
(07:45)
Aging:
"Having and using muscle is one of the most effective ways to slow the whole aging process."
(07:45)
Muscle mass declines:
Cognitive Benefits:
"Resistance exercise has been shown to improve cognitive function and memory in the elderly with cognitive decline."
(09:10)
Mechanisms:
Depression and Anxiety:
"Exercise is more effective than counseling or medication for alleviating depression or anxiety."
(12:00)
Psychological Benefits:
Resistance training leads to:
Mortality Reduction:
"Resistance training can actually reduce all-cause and cardiovascular mortality by 29%."
(15:00)
Additional Benefits:
Testosterone and Estrogen:
"Resistance training stimulates the release of testosterone, improving libido, sex drive, and sexual performance in men."
(18:30)
Women's Health:
"Resistance training helps increase estrogen, important for bone health, and improves insulin sensitivity, aiding conditions like PCOS."
(19:00)
Dr. Lyon provides actionable steps for beginners:
Minimum Effective Dose:
"Research shows that just one workout per week, one set per exercise, is sufficient to maintain strength."
(12:45)
However, she recommends more frequent sessions for optimal benefits.
Beginner Routine:
A full-body workout incorporating exercises like:
Time Management:
"Even if it's only 15 minutes broken up into 5-minute chunks throughout the day, just do something right."
(16:50)
Travel-Friendly Options:
Utilizing resistance bands or bodyweight exercises to maintain consistency while on the move.
Increased Frequency:
"60 to 75-year-olds will need two workouts a week with two to three sets per exercise. Ideally, three to four times a week."
(16:02)
Exercise Variety:
Alternating between upper body and lower body workouts to ensure balanced muscle development.
Intensity and Volume:
For those seeking muscle growth and increased strength:
High Ground Activities:
Emphasizing exercises that require greater muscle engagement and stability, such as hack squats and assisted deadlifts.
Dr. Lyon transitions to the critical role of protein:
Amino Acid Functions:
Each essential amino acid has unique metabolic roles:
Protein as Nutrition:
"We need to eat muscle to build muscle. It contains all the building blocks to build muscle."
(32:19)
General Guidelines:
"You need about 1 gram per pound of ideal body weight if you're trying to build muscle. For maintenance, 0.7 grams per pound is sufficient."
(33:45)
Protein Hierarchy:
Dr. Lyon emphasizes a higher intake than the RDA to support optimal health and muscle maintenance:
Quality Differences:
"Plant proteins have lower quality based on digestibility and amino acid profiles. They often require a higher intake to match the benefits of animal proteins."
(34:04)
Supplementation Needs:
Vegans may need to supplement with specific amino acids, like leucine, to ensure adequate muscle protein synthesis.
Practical Consumption:
First Meal Importance:
"The first meal of the day should contain between 30 and 50 grams of protein to counteract overnight catabolism."
(42:23)
Post-Exercise Consumption:
Consuming protein within 30 minutes to an hour after resistance training optimizes muscle repair and growth.
Meal Distribution:
While total daily protein intake is paramount, distributing protein intake across meals, especially at breakfast and after workouts, enhances muscle synthesis.
Sourcing High-Quality Proteins:
Emphasizing grass-fed, regeneratively raised meats and wild-caught fish for optimal nutrient profiles:
"Grass-fed meat has higher levels of omega-3 fats, minerals, and antioxidants."
(56:36)
Supplements:
Recommending high-quality whey protein options, such as goat whey, for those who prefer supplementation:
"Goat whey is a powerful protein source with fewer allergenic properties."
(35:30)
Balanced Meals:
Start meals with protein to enhance satiety and regulate insulin response, avoiding high carbohydrate intake first.
Protein-Rich Breakfasts:
Replace sugary breakfasts with protein-focused options to support muscle synthesis and metabolic health.
Example Protein Sources:
Dr. Mark Hyman and Dr. Gabrielle Lyon underscore the indispensable roles of weight training and adequate protein intake in combating the metabolic health crisis, preventing chronic diseases, and promoting longevity. Key takeaways include:
Integrate Regular Resistance Training:
Essential for maintaining muscle mass, enhancing metabolic function, and reducing disease risk.
Optimize Protein Intake:
Aim for 0.7 to 1 gram of protein per pound of ideal body weight, prioritizing high-quality sources and strategic meal timing.
Customize Approaches:
Tailor exercise and dietary strategies to individual needs, age, and activity levels to maximize health benefits.
Holistic Health Perspective:
Combining strength training with proper nutrition supports comprehensive health, including mental, cardiovascular, and immune systems.
Notable Quotes:
"Muscle is the currency of longevity. Those with lean muscle tend to live longer."
"Resistance training boosts immune function, enhances the activity of immune cells like natural killer cells and T cells, and increases antioxidant enzyme production."
"Exercise is more effective than counseling or medication for alleviating depression or anxiety."
"The only way to do it wrong is to not do it."
For more detailed insights and personalized health strategies, listeners are encouraged to explore Dr. Mark Hyman's resources and consider consulting with healthcare professionals.