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Today's episode is sponsored by my good friends at Timeline. Timeline is now offering the world's first ever longevity gummies, powered by Might Appear. You've heard me talk about the importance of cellular health and our mitochondria, which is why I have Timeline as my favorite and most trusted sponsor. These are the only clinically proven Urolithin a gummies for strength and healthy aging. We may be living longer lifespans, but are we truly living better lives? What if the key is not just adding years to your life, but life to your years? This all starts at the cellular level. As we age, our mitochondrial health starts to decline. And one of the keys to living longer and healthier is keeping our mitochondria healthy and strong and might appear targets that for us, take control of your health now and live the life that you not only desire, but you also deserve. As a gift to all my listeners, you can save 20% off today by going to timeline.combackslash Dylan to get started. That's timeline.combackslash Dylan. I assure you your cells will thank you. All right, everybody, welcome back to the Dylan Gemelli podcast. And I am on cloud nine today because I have been waiting for my guest for quite a while and we've been trying to work this out and he's one of the ones that I have wanted for a very long time. So I am super thankful that he got some time with me today because you know, the schedules with people, it's crazy. But I'm going to give you a little intro, brother. I can't really do you justice, but he does it all. He. Listen, he's one of the mainstays and I would argue one of the, if not the most influential, I would say at least top two to three in the last at least decade in biohacking, health, fitness, wellness, you name it. I would definitely put him at my top of my list of go to people well respected, well renowned. Just quickly, he's a New York Times bestselling author. I'm sure many of you have seen his, his books, Boundless. He's got this big podcast. He's a former collegiate tennis, water polo, volleyball player. He's a 13 time Ironman, triathlete. He's been voted by the NSCA as America's top personal trainer. He's done it all. I, I'm not going to spend the whole podcast talking about his accolades. But my friends Ben Greenfield and I.
B
Suck at baseball and golf.
A
Been there, brother. Hey man, thanks for coming on here with me today. I have been Looking forward to this. Like I said for such a long time, I want to start off with diet. I, I've been doing a lot of things with diet the past several years and I've been running into so many different people on the carb side, against the carb side, people that want to argue, fight over it. Where do you stand on diets? And, and do you have a specific go to or what's your feeling on the polarizing topic of carbohydrates?
B
Yeah, just come out swinging with an easy question, huh? Yeah. Well, as you know, as you know, the dogmatism behind diets kind of ranks right up there with religion and politics. Probably not assisted much by the idea that religion and nutrition are often kind of intertwined in some ways. You know, whether you eat pork and shellfish and whether cows are holy or not, and you know, all the elements that kind of go into the spiritual side of diet. It's probably why it's, you know, so dogmatic or one of the reasons. There's, there's a book that goes back to like the 60s called biochemical individuality. It's based on the idea that human beings have different vitamin D excretion rates and different oxalate excretion rates and a different size of the pancreas and the liver and the stomach and the gastrointestinal tract. And when you pair that with this new era that we live in, this era of self quantification, where now we know we have, you know, wild variants in genetics, in detoxification capabilities, in methylation capabilities, in blood flow and nitric oxide capabilities, and we also have different microbiomes, possibly parasites, yeast, fungus that may influence our nutrition choices or the impact of those. We have different hormone statuses. There is no reason for anyone to say there is one perfect diet for all of humankind and there is no reason for anyone to follow one perfect diet for all of humankind. Because the, you know, the, the ribeye and sauerkraut diet might completely screw over somebody with, let's say, like over methylation issues, who is, you know, who, who needs a higher amount of glycogen and carbohydrate due to their physical activity, who might even have some kind of like an inflammatory response to saturated fats, cuz they have like, I don't know, an APOE4E4 gene or something like that. So I think the best way to go is to test, to self quantify and to figure out based on your genetics and your blood work and your activity levels and lifestyle and goals what diet is gonna work best for you? And then if you just like can't afford to do that, you're living paycheck to paycheck, you're listening, and you're a college student on a budget. You could make a pretty good case that possibly based on human origin in the Fertile Crescent, I don't know, possibly due to the fact that it's just a, A, a diet that's relatively diverse, so it grows the microbiome pretty well, I would say some semblance of a Mediterranean diet. A pretty good idea. And not like the unlimited breadsticks, you know, giant salad bowls, Mediterranean diet, but, you know, a diet rich in omega 3 fatty acids with vegetables both fermented and raw, and extra virgin olive oil and plenty of omega 3s and nuts and natural sources of cheese and a little bit of red wine here and there. You know, all the things that you would tend to see somebody, I dunno, sucking down in Sardinia, you know, that, that seems to work pretty well for somebody who just wants to throw a dart and hope that they hit the right diet. And then the carb piece, I mean, that again is, is an area that's rife with a need for customization, Dylan. Yes. So for the most part, being aware of carbohydrate intake and controlling added sugars especially to some extent, is a good idea. I mean, I wear this blood glucose monitor. It tracks my glycemic variability, how much my blood glucose goes up and down throughout the day. That's more important to me really than my average blood glucose. It's just like how many spikes I get and how long it stays elevated after a meal.
A
Right.
B
And in a sedentary person, in someone managing metabolic disease like a diabetic condition, even someone with like epilepsy, seizures, post tbi, post concussion, et cetera, you could make a case that like a low carb diet would be healthy at anywhere from 20 to 50 grams of carbohydrates per day. A so called ketotic approach or ketogenic diet. Right. And then let's say like an ironman athlete or a crossfitter or even just the average gym junkie or a guy like me who's like working out an hour a day, you know, and then whatever, walking on a treadmill while I'm talking to you and burning a decent amount of calories, you know, for me, and I do this low carb diet is closer to 200 to 300 grams a day. All right, so, so part of it is, is who are you and what's your lifestyle, and what would low carb context be for you? And when I say 200 to 300 grams per day, I actually time that. So I eat very few carbohydrates most of the day. I'm gonna have a little bit of, like, a handful of blueberries sometimes in a morning smoothie or, like, half a banana. Um, and, you know, so I'm usually having some kind of a great smoothie, you know, like a superfood smoothie for breakfast. I have, like, a big salad with back to the Mediterranean thing. Sardines, anchovies, extra virgin olive oil, seeds, nuts, et cetera at lunch. And then dinner tends to be the most widely varying meal of the day. Just like socially and logistically, you might be out at a restaurant, you might have friends over, you're hanging out with family. I'd rather have that be the time when I have the most flexibility for macros, where I can grab the sweet potato fries and my wife's sourdough bread and. And, you know, a bunch of, you know, beets and carrots and parsnips and potatoes and maybe a little dark chocolate and yogurt and berries for dessert. And the cool part about that approach is carbohydrates can also assist with production of serotonin, which then downstream can help to produce melatonin to give you better sleep. The only kickback you hear sometimes with this approach is a lot of people have heard, rightly so, that you're more insulin sensitive in the morning, meaning you would, theoretically, from a hormonal standpoint, be better equipped to shove glucose into muscle and liver in the morning versus the evening. But it's pretty easy to induce a temporary state of insulin sensitivity. And I recommend somebody does this before or after any meal. You could go for a walk, you could, you know, lift weights in the early evening before dinner. You can even do, like, a cold shower or a cold plunge. For me, between, like, 6 and 7 is about when I'm finishing up work. So I go, like, I go hit a little bit on the pickleball court or play some tennis or a little Frisbee golf, hang out with the family, go for a walk, and make the last couple phone calls of the day. So, yeah, I mean, if you're just kind of like a sedentary slob for the hours leading up to dinner, carbs might actually hit you and cause a little bit of a blood sugar spike. But if you're physically active and, you know, and you understand the idea of even just like a 5 to 10 minute pre dinner and or post dinner walk, it kind of becomes a moot point and becomes even more mooter of a point, if that's a phrase. If you've been restricting carbohydrates the rest of the day because your muscles, assuming you're, you're physically active, are kind of like a little bit of a metabolic seek for glucose and they're a little bit deprived at that point in the day. So you know, long story, short summary of everything I just said is test yourself, self quantify and customize your diet to you. And if you can't follow some semblance of a Mediterranean diet, strict carbs, but not excessively, unless you're managing some kind of a disease. And if you are able to time your carbs so you're having more of them in the evening.
A
See this is one of those times where I like to point out to everybody when you can really tell you're talking to somebody with like credibility that's not relying on emotion when they talk about something. Because when you bring up the fact that it's all personal, person to person specific and customizable, that's just basically everything in life. And when we fall into these traps where you get on these hardcore rants that this is the only way and it has to be like this. And I see people arguing without understanding that there are so many different conditions and people, like you said, the way we're training, I mean I train, I don't know, man, almost three hours a day between cardio one set and then lifting at night and I don't get enough carbs. I know it. And like you said, there's situations where it's necessary. So then that brings me to my next question. Diet related because you, I mean you covered everything so intricately for us. Let's take a look at the fasting side of things. I've done a lot of study on this in terms of the cellular health, the long term longevity and, and I'm very spiritual. So as you pointed out, you know, that goes back to the beginning of time. So there's reasoning for it. What's your thoughts on fasting in general? Do you incorporate it and, and if you do, how do you go about that with somebody that's training heavy?
B
Yeah, that's funny you mentioned prayer. There's actually an old book, it's called something like the Atomic Power of Prayer and Fasting. Cheesy title, but it goes into how a deeper spiritual connection with God and a deeper prayer life can result from bouts of fasting that are intentionally built for a spiritual habit or purpose. Which, which of course, you know, that's. Most people know that a lot of religions have some kind of practices, fasting that's woven in. So my opinion on fasting and then my opinion on fasting for what did you say someone who's very physically active?
A
Yeah. At top level athlete or someone train like we do?
B
Yeah, yeah. I mean it's. When you're looking at a top level athlete. First of all, just to touch on that first, you know, most athletes do need to hear that performance is not necessarily synonymous with health. Right, right. I spent 20 years, as you mentioned briefly in the bio, doing all sorts of different sports at a pretty high level. And then Ironman triathlon and Spartan racing and adventure racing. And there would be some weeks where I was exercising like 20 plus hours and you know, races where I'd be going more than three days and at least 10 plus hours. And while those kind of things are great for character development, for endurance, for perseverance, for climbing your own personal Mount Everest, you shouldn't fool yourself into thinking that extreme exercise is long term going to be healthy for you or increase longevity. Right. It's interesting because the true definition of temperance is not complete restriction or abstinence from a certain activity, but instead the ability to be able to modulate or self control your usage of it and achieve a so called Goldilocks zone. So it exercise, you know, temperance is prudent. And if you look at research on let's say cardiovascular exercise and its effects on cardiovascular health, there is a Goldilocks zone once you exceed about 75 minutes of very high intensity exercise, which barely anybody achieves anyways. But there are some crossfitters, some extreme athletes who would exceed 75 minutes of what would be considered if you're using zones like zone four, zone five cardio, you know, above lactic acid threshold on a weekly basis. And once you exceed about 150 minutes or so of moderate intensity exercise, which a lot of cardio bunnies, you know, and frowny face treadmill people at the gym, do you start to see arterial stiffness and early onset atherosclerosis. You know, it's, it's just inducing too much inflammation without enough recovery.
A
Yep.
B
And there's some people who are like, wait, like human beings are primal creatures. We were built to move, baby. We should be like moving all day long. Yes. But you know, for anybody who's gone like hunting or has a garden that you're out in during the day, or even has manual labor like construction work or painting or fence building or something. You're not like running from a lion all day long during those activities. You're starting, you're stopping, you're at a low level intensity. It's aerobic and conversational. Like I'm talking to you right now. And so it, I'm really talking about the stuff that actually kind of beats you up. So if you are back to the fasting piece, fitting into that category of an elite exerciser, a gym junkie, an athlete, then you also need to accept the fact that since performance is not synonymous with longevity, some of the things that you're doing to support performance would also not be those things that have been studied for longevity. And fractioning could be one of those excessive calorie restriction and even compressed feeding windows which can hinder your ability to be able to fuel enough to restore muscle glycogen, to be able to get enough proteins and amino acids in for repair and recovery, to be able to hit an anabolic window. It's, it just becomes more difficult, not impossible, but more difficult when you're fasting. All the more so if you, like you mentioned Dylan, are like a two a day type of athlete. So I think that for a high performer it's reasonable for, for males to go for anywhere from 12 to 14 hours. And I think that's pretty doable. Yeah, as a, as a daily intermittent fast. You would even still be semi breaking that fast if you had an early morning workout. So that would look like you're gonna finish eating dinner 8pm and then let's say your workout starts at like, I don't know, what do we say? It's late, we'll say it's like 9am Right. So you're starting your workout with a 13 hour intermittent fasting window. You plan on having breakfast around whatever, 10, 15 when you get out of the gym and get your hands on a, on a smoothie or a post workout meal. Well, even then you could battle some of the catabolic effects of that fasting window, which you might have been doing for longevity, maybe a gut break, et cetera, by using ketones pre workout and by using essential amino acids pre workout. And I actually have a lot of my clients and athletes do this. I'll give them a little bit of the baby benefits of a short term intermittent fast and then they're doing like a shot of ketone IQ 1, 3 butane dial or a shot of like ketone aid beta hydroxybutyrate or some variant of a ketone, which isn't gonna impact blood glucose and arguably not only keeps your body in a fasted state, but magnifies the benefits of fasting and then essential amino acids, especially leucine enriched essential amino acids to be able to stay anabolic with a very small rise in insulin with minimal calories. So that's how you would do it if you were, if, if you were kind of an exerciser who wanted the benefits of fasting. You do like a 12 hour intermittent fast, 14 at the most. And then you do ketones and amino acids pre fasted workout. If you're a female, that window shortens. Well, specifically if you're a pre menopausal female, perimenopausal postmenopausal females, it'd be everything I just said. Premenopausal females would be closer to 10 hours. You tend to see a downregulation of kisspeptin, which is an upstream hormone that will assist with fertility regulation and endocrine regulation. If you are going for longer than 10 hours regularly as an overnight intermittent fast. So if you're an even more of an issue if you're a lean female, females should be a slightly shorter intermittent fasting window. And then, you know, the number one thing that people who are familiar with fasting might be thinking is, well Ben, I heard you get all the benefits of fasting. Once you exceed like 16 hours, real autophagy starts to kick in. And that is true. But you don't need to do that daily. And what I do with my more active clients is we do one to two times per month a 24 hour dinner to dinner fast. Right. Quitting on Saturday evening. Don't eat again until Sunday evening dinner. And we try to time that on a recovery day. So if Sunday's a recovery day, then you're not gonna need a ton of glycogen, you're not gonna need a ton of anabolic factors like protein and amino acids. You know, just quit face stuffing on Saturday. Get your 24 hour cycle in a couple of times a month after that. Could be pretty good for cellular autophagy and cleanup without the stress. For an active person of more regular fasting periods. More regular long fasting periods.
A
Awesome. Great breakdown. I'm going to touch on multitude of things that you kind of touched on there. One thing I'll say that I, I understand now, which I wish I did earlier, was the abusive amount of cardio that you said. And I want to convey that double time, that overdoing it like anything Else can have obviously an adverse effect. I, I did a calcium score a couple years ago and found plaque and thought what is, how is this even possible? And I think a lot of that correlation is Training in Zone 4 Too many years too long and doing it for overextended periods of time. And I actually found a low ejection fraction on top of it. And so it's been this years of study now for me on the heart and learning about like several things that you're talking about and how to combat and overcome that and then teach others that are abusing themselves that think they're doing good, where in fact they're harming long term. So I, I definitely want to get into some heart things with you, but I, I do want to touch on something else first.
B
By, by the way, the one saving grace of the type of plaque accumulation that occurs with hard exercise is that it does tend to be more stable and, and tightly packed Y. So that is nice. It's usually less due to excess fat accumulation and foam cell production and a little bit more of like a tight packed inflammatory response. Still an issue if it builds up long term. Less of an issue than someone with unstable plaque.
A
Let's stick with that then because that's. Those, those are fabulous points and I want to get into that with you because I think you're extremely well versed and I like to think now after what I've gone through the last three or four years, that I can go back and forth with you on this. So this will be good. Let's talk about that. So you said stable plaque and then obviously the fear is the soft plaque. And, and so we're trying to A, avoid that and B, learn how to figure out how we can even find that in comparison to the hard plaque. And so for me, the, you know, we go in stages, right? We got the calcium score, we got a CT angio and you can get a little bit more intricate. Like I was in there and I had a catheter done and checked because I had a bout of cart palpitations. But then we go to the clearly test which can actually show you the differentiation between soft and hard plaque. Can you kind of get into the dangers of soft plaque a little bit and then how we can figure out what is what and what we need to look for?
B
Yeah, a few subtle nuances on the diagnostics piece of it. You know, most people just do the lipid panel, which is, it could give you clues. But you know, lipid panel isn't necessarily reflective of tissue cholesterol deposition. It shows you what's floating around in the blood and there is some correlation. But I have seen, and by the way, I am not a doctor, do not take any of this as medical advice.
A
Right.
B
I've seen people with very good lipid panels present with elevated plaque scores.
A
Me too.
B
And vice versa. People with pretty shitty lipid panels who don't appear to have significant plaque accumulation. That's why, you know, unlike full body mri, which is questionable as far as like, necessary diagnostic imaging, largely because of the amount of false positives you'd find with it. Some type of diagnostic imaging for the heart I think is pretty smart. Now, the easiest, lowest hanging fruit would just be a carotid ultrasound.
A
Yep.
B
There are websites like vasolabs.com where you can find a technician, it's called a CIMT carotid, into a media thickness score. And it's just the non invasive ultrasound on either side of the neck that can correlate with decent, not perfect accuracy, but decent accuracy to what's going on in the heart by calcium in the carotid can kind of indicate what's going on in the heart. And then you step up to a basic calcium scan score, which a lot of people are familiar with or have done, which kind of gives you a score just like it sounds like it'll, it'll tell you, hey, you have calcium or you don't have calcium. And it can differentiate visually a little bit between stable versus unstable, soft versus hard. But it's not the greatest. It's kind of like the old school scan compared to what you were just describing, Dylan, which would be a CT angiography and especially a form of CT angiography called the clearly scan. This would give you not only stable versus unstable plaque, but with pretty good precision, the location where that plaque resides and the amount of infiltration in the vasculature. Um, and there are some concerns about radiation from that test, especially if it's done on a repeated basis. The faster the machine, the less radiation. So the really fast machine, you get less radiation than a cross, you know, country flight to New York City from California. The slower machines, you could make a case for, you know, taking some iodine afterwards and not doing it any more often than maybe a year and a half. But even just doing it once, you're going to get pretty good information about the plaque, where it resides, whether it's stable versus unstable. And this is all interesting, but I think what's more relevant and important is what to do if you find flak that's That's a million dollar question, like what do you do? Because if you find the plaque, it is going to progress. You know, it can be stable or unstable if it's unstable, if it's soft, it will progress more quickly, but it will progress no matter what. You know, it'll almost act like a little bit of a fly trap for additional deposition over time. The gold standard in allopathic medicine for plaque regression. And, and I don't really have a problem with this approach, although it, it can create some side effects and it can be expensive for some if insurance doesn't cover. It would be a low dose statin combination like zetimibe and rosuvastatin. That'd be an example. I forget it's 5 of 1, 10 of the other in terms of milligrams. I forget which. And that's a pretty low dose of a statin. And the only reason I'm saying this is there's actual research on plaque regression with that combination. And then often that would be combined with what's called a PCSK9 inhibitor, which basically upregulates expression of LDL receptors and gives LDL more to attach to. So it has left plaque deposition that's going to occur. The, the issue would be PCSK9 can be expensive and I personally would be, and this is pure theory. I just wonder what happens systemically if we upregulate LDL receptors long term because that would mean less cholesterol available potentially for things like the endocrine system, the brain areas that we know if we haven't swallowed the high cholesterol is bad for you. Tagline, hook, line and sinker might be impacted with long term use of the PCSK9, but I don't know. That's pure theory. And then with the Loto statin this is less of an issue, but it's still an issue. There is some risk for a coenzyme Q10 stripping and muscle soreness. So you definitely want to use Ubiquinol or CoQ10 or kind of top of the totem pole based on research by Dr. Barry Tan would be something like Annatto extract, which is kinda like mixed tols and tocotrienols that can help to stave off CoQ10 degradation. Even better than just taking CoQ10 or Ubiquinol. So that would be like the allopathic approach, right? Low dose statin combo with PCSK9 sometimes by itself, sometimes PCSK9 by itself. You could make a case for any three of those having an impact on plaque regression. Downsides for what I just mentioned, plus the expense, the, the natural approach. Even though there's, there's a lot of things that, that might be good, like red yeast, rice extract, so called major statin, niacin, magnesium, even things that aren't supplemental or, or oral nutraceuticals like red light therapy. So which would help to structure water in the cells and assist with membrane fluidity exercise. Of course, to a certain extent, you know, within reason. Pulse electromagnetic field therapy, which would reduce red blood cell adhesions and assist with blood flow. Anything that would increase nitric oxide production even from a dietary standpoint. Right. Beets, beetroot, watermelon, you know, arugula, assuming you have a clean mouth. Right. Mouthwash can nuke some of the bacteria that assist with conversion of dietary nitrates into nitric oxide. So don't use mouthwash excessively. But you know, a nitric oxide rich diet, you know, a little bit of a baby tadal, you know, like a baby calis or a baby Viagra, like sildenopil. Um, but I would say top of the totem pole in terms of plaque regression. If you did want to go to the natural route would be metalkinase and lumbrokinase, you know. Yep. Nattokinase is the easiest to find in supplemental form. Most supplements only have it at about 1,000 to 2,000 units. It'd be hard pressed to find any data showing an impact on anything less than 8,000 units. So you got to take a lot of Natto kinase if you're going to use that as a strategy. But that would be, of all the things I've seen the best. I'm going to throw this in there too. I, I spent a couple of years digging into this for my own personal interest in use. And I worked with a company called Vitaboom. They created a product called Heart Health and it has about nine of the different nutraceuticals that I identified as being effective for plaque regression. If you did want to go the natural route, I realize I like, I sound like a fox starting the hen house right now, but I'd be remiss not to mention it. And then recently increased, based on the data, I was seeing the nattokinase dosage from 2000 up to 10,000. So that's like a, a clinically effective dose arguably of nattokinase in it now. So, you know, some, some things that you can do either going the natural route or the pharmaceutical route paired with some of those lifestyle factors. And I think it is important I mean, and a lot of women are like, well these are two dudes talking about having a heart attack. You know, it's even called the widowmaker, right?
A
Yes.
B
Yeah. Perimenopausal postmenopausal women have a shockingly increased significant risk for heart disease. And so this is something older females in particular should be worried about too.
A
Brother. Had I Not checked at 41 years old, this would have been progressing, progressing, progressing. And I would have had no clue because I am like a full blown seven day a week or almost in and going non stop. I take, you know, rest, but I mean I go, go, go and I would have never had a clue. And so I'm thankful I did. I want to run a couple things by you that I found and that I was told and I'm smiling at a lot of things you're saying because I'm like, man, he's dialed in. So one, the nattokinase, there's a one and I, I don't work with them by any stretch, but Natovina was the one I use and it. They have a higher count on their pills and I use that one. So I do like 12,000 a day was what I was doing because I read in studies that was where it was really actually reversing plaque. And PA Grant juice is another one that I have found because I had gone back and I have been able to reverse plaque. But my situation was an elevated LP and it was up to 3:30 which is as you know, insanely high. My dad died of a heart attack at 59 and so reversing that is not so easy. I've been able to get mine down to 90 in the 90s which is pretty miraculous.
B
God's grace. And a lot, a lot of classically trained physicians will tell you LPA is not modifiable at all. I disagree for the same reason I disagree with people who say VO2 max is not very modifiable. Yeah, I would, I would say by traditional methods. Yes. Possibly even just by following a normal heart healthy diet. Yes. But by introducing. Did you do like high dose niacin for the LP or did for a.
A
While I started to get really, really elevated liver because I was slamming that with the red yeast rice. So I backed off. Both got my liver under control and what I, I am on PCSK9 of Repatha and then I take Vascepra. I dropped the statin completely because I wasn't enjoying some of the, the feeling with it. But I had, they had dropped my cholesterol into the 30s, and I panicked. And I had. Now, with the higher animal fats and, you know, more good, clean fats and saturated fats, I'm back up to 80 LDL, which I know some people panic, and I'm like, listen, that's actually quite good, even with, you know, having some plaque, considering I got my HDL up that high. But the. I went to the Mayo Clinic, and they told me using PCSK9s would be bad practice. And I was just looking at them like, thanks for making me drive three hours to waste my time, but I am thoroughly with you on everything you said. The natural things that you said, the baby aspirins. I'm gonna talk to you after about that product you mentioned. But I think the point here is that looking at your heart, even if you think you're too young, is of the utmost importance. When would you tell people to start really getting into it and looking at it?
B
If you have a family history of cardiovascular disease and you're a man, I would start as early as 30. And again, I'm not a doctor, but that would be my recommendation. And. And women is tougher to say. I mean, I would say at least right around perimenopause symptoms setting in, but. And this is a can of worms, dude. Um, you know, now we have athletes dropping dead on the field of practice at an increasing rate due to some type of vascular infiltration or inflammation. It appears that the most likely culprit is spike protein.
A
Yeah.
B
Induced from either getting Covid or getting a Covid vaccination. So these are young people.
A
Right.
B
And Covid spike protein is not going to show up as a plaque issue. That's kind of a problem is you're going to be more, like, looking at inflammatory markers, cytokines, H, S, C, R, P, et cetera. But now it's like, gosh, like, you know, just in terms of. Of checking on heart health. Overall, I would say 30 is a good time as a guy to really start paying attention to it and paramenipause for women. But then if you've had Covid and it was pretty bad, or you've done the vaccination, especially a full series of the vaccinations, you should probably start tracking inflammatory markers in particular even earlier than that. Like, pretty much asap.
A
It's difficult. I'll tell you. I've had Covid, I think, seven or eight times, no vaccination. But when I had the low rejection fraction, I related it to that. But all of my inflammatory markers are fucking, like, zero. So It's. It's kind of an anomaly. I'm trying to figure out what it is. I still feel like there's Covid reaction there somehow.
B
I suspect that beyond inflammation, there might be an impact on arterial elasticity, stiffness, I think. So that. That is measurable. Typically you can use like, like a photonic, like a photobiomodulation measurement for that. There's some like frequency scanners that will do it, you know, and it's kind of tricky because part of it comes to just like getting the spike protein out and that. I mean, that would literally involve flying to Vienna or London or Tijuana. Like, at least those three places have clinics where they have a blood filtration unit. You know, I've done it. Yeah. I lay in a hospital bed for two or three days and just pulls your blood out and passes through a filter design to be like a sticky fly trap for the Spike protein. The one I use called the Serif filter, and it was designed specifically for this. And then it goes back into the body.
A
Yeah, for sure. That's good to know.
B
Not like thousands, thousands of people aren't going to go pay, but it's like, it's like depending on, on how you're doing it, like anywhere from like 15 to $30,000 to do that.
A
It. Everything is just like when you brought up the repath. You know how hard it was for me to get, like the insurance to cover a path. They have to literally elevate your triglycerides and you have to be allergic to a stat. I mean, it, it's a list of things to get it approved and not.
B
It's super expensive. Like, like $3,000 a month on average.
A
Yeah, it's. It's insane. If you do good Rx even, it's like 750. It. It's just unaffordable. So it's. And that sucks for people that are really trying. And then for me, I've already got ultra low blood pressure. So when you're doing something to fix your ejection fraction, you're very limited on what you can take. So these inrestos and these other. I can't do it. I tried. And so Jardiance has been the one I've been relying on right now with D ribos. High ubiquinol. Like very high ubiquinol. And so I have a echocardiogram followup in a couple weeks to measure it again because it dropped to 45, which is not heart failure, but clearly low, so.
B
Which dropped to 45.
A
The. My ejection fraction.
B
Okay, yeah, yeah, yeah, yeah.
A
So it's. Dude, it's. And I swear it's Covid related. But I want to talk to you.
B
About some cellular on before we get shadow banned, bro.
A
All right.
B
No, I wanna.
A
So I, you know, like I told you off camera, I spent decades just really in fitness and bodybuilding and you know, more focused on that nutrition. But I started working with timeline over a year ago and I really got into the cellular and biology side, cellular health and talking about that. So I want to talk to you about the importance of cellular health. And, and for me it's like all disease and everything health related really starts there with our cells. How important is it to you to take care of cellular health, mitochondria health on your list of things? Because you know, people talk about the gut, people talk about so many different things, but I think everything really starts and ends with cellular health. What do you think?
B
Well, I mean, you kind of cheated there, cuz the gut is cellular health. Well, yeah, I mean like, it's kind of like. How do I, how do I not agree with your question? Because cellular health and mitochondrial health are basically the foundational principles behind every organ system because every organism has cells and, and almost all of them mitochondria. And so it's important, and you know, I, I think that a lot of people are aware, you know, so at least remotely aware of the type of things that would improve, in particular the health of the cell membrane or the electron flow or electrochemical balance across the cells, including the electron transport chain and the mitochondria. But let's name a few just to make sure people have these bases covered. Um, so for the cell membrane proper fluidity and rigidity, we kind of briefly touched on this with the cholesterol piece, but it would be avoiding a completely fat phobic approach to diet eating. Back to earlier in this podcast in a more Mediterranean fashion. So you can go out and you can get a test called Omegaquant, which is just basically an omega index score, and it'll show you a percentage of your omega fatty acids. And it's a ratio of omega 3 to omega 6s and you want a percentage, preferably at 8 or higher. Even though the reference range cutoff is at 4, I think you can make a pretty strong case for being at 8% or above. So you would achieve this by getting a good balance of fats in the diet and in particular prioritizing omega 3 fatty acids. And if you don't get a lot of them from your diet, taking 1 to 2 grams of fish oil a day. Next part would be quelling of reactive oxygen species that would occur in response to mitochondrial energy production. Um, you mentioned the gut. And the cool thing is this strategy is a 1, 2 combo for both the gut and for that reactive oxygen species quelling. And that would be dietary diversity. Right. We live in the salad as a lettuce, you know, mini carrots, tomato and ranch dressing culture. But when you increase the plant diversity in particular that you take in, not only do you develop a more robust microbiome, but you expose yourself to a higher amount of the flavanols and polyphenols that help to quell the reactive oxygen species and to even the plant defense mechanisms that increase your own endogenous antioxidant production. This is why I'm a bigger fan. If someone were to follow, like, a carnivore diet of something like the modified version of it, where you're doing a carnivore diet but with fermented vegetables, kimchi, sauerkraut, et cetera, or I mean, if you could also just use like, one of these, like, reds powders, greens powders, whatever. But you are missing out on that aspect of dietary diversity with something like a carnivore diet. And paradoxically, the more you limit your intake of things like, you know, gluten, lectins, a 2 casein from dairy, et cetera, the less robust your microbiome population becomes and the less able you are to digest those foods. Hence, parents who heavily restrict peanuts with their children have older children with peanut allergies. Parents who excessively restrict gluten with their children have ch older children with gluten allergies. And I'm not saying, like, you know, like, if you paint the back of the toilet seat after you go out for pizza and you have total, you know, actual allergies or severe intolerances to, like, dairy or bread or pizza, like, don't eat it. But if you excessively restrict dietary diversity or even don't just, like, go and seek out some extra things like shoots and sprouts and microgreens and eight different things on your salad instead of three, you are gonna short yourself in terms of flavanol, polyphenol intake, dietary and microbiome diversity. So that'd be the next thing to think about. The next would be down to the electrochemical piece. To maintain that proper charge, you do need adequate minerals. Monocropping and fertilizer use can restrict. And I'm not just pulling this on my ass. You actually do see restricted mineral production in plants that are heavily sprayed and plants that are grown in stripped soil. So we're not getting as many minerals in the average diet. So using things like trace liquid minerals, using really really good salt, and salting your food using electrolytes, all the more so if you're using like really good water purification, cuz that will pull some of the minerals out. But being really cognizant of adding minerals back to your food, eating mineral rich fruit, of course, you know, eat organic when you can, or at least eat, you know, non herbicide pesticide spray even if it's not certified organic, and then just basically add a lot of minerals back into your diet. And then the last thing would be, there are certain elements of nature that can assist with that electrochemical balance or with the activity of the electron transport chain and thus mitochondrial energy production and electrochemical balance across the cell membrane. Some of the biggies you'd see kind of big in the biohacking world right now. Pulsed electromagnetic field mats or coils that you lay on, stretch on, sit on, et cetera, P, E, M, F, grounding and earthing. Like going outside barefoot using a grounding mat or an earthing mat, wearing grounding shoes, et cetera. Every time lightning strikes the surface of the planet, or solar radiation bombards the surface of the planet, it collects these ions. There's transdermal connectivity. When your skin touches the earth, touches the beach, jumps in the ocean, whatever. So that's another way to charge up the body. Sunlight specifically. You know, this is why you see such a surge in infrared saunas and red light panels and red light beds. And photobiomodulation is the, is a technical term for it. Those spectrums of light are well absorbed by different protein complexes in your mitochondria and can increase activity of the electron transport chain and thus ATP production. Kind of like a plant would photosynthesize. Right? So, and I'm not saying you can live on sunlight for those guys, but it could definitely help out with, with energy production and mitochondrial and cellular health. Um, I focus on that. And so if we come full circle, I would say just to name a few of the basics, good fat intake, especially from Omega 3 or Mediterranean style fats, good dietary diversity. Pay attention to a lot of these variables like earthing, grounding, pemf, sunlight, et cetera, and then good mineral intake.
A
I'll tell you, Ben, I spent, I was a fashion model in my 20s and then I, I've done so much work on camera you had a little.
B
Bit of a Zoolander look about you.
A
Not anymore. I'm. I'm older now, but I've struggled with like an, just a body dysmorphia and eating disorder even as a nutritionist. Probably why I started studying nutrition so young. And I. You brought up the fear of fats. And, And I'll tell you, I lived the last 20, 25 years of my life in that fat, fat phobic, eating 15, 20 grams of fat a day till about a year ago. And when I made that shift, I'm up to like 130 grams of fat now. And I'm telling you, man, like, my health, my clarity, my ability to sit and focus even when I don't sleep enough and the overall feeling and the skin, just everything. I mean, it has changed my life. And it's not like I didn't know it, but I'm glad you brought it up because I like to tell people like my struggle so they know what a mistake. And also I'm pissed off that I wasn't cooking and Kerrygold and getting all these foods and enjoying my food for so long, you know, but shallow. Yeah, man, but you know, just the amount of avocado and whole eggs I was eating like all these just egg whites, lowfat yogurt, and it's just a garbage diet. And, and you think you're doing well and you're not, you're actually hurting yourself and hindering yourself and, and it's, it's. I'm glad you brought it up, man. I really am satiating too. Geez. So I never angry during the day anymore or short wicked, or every 30 minutes getting up to go take a bite of peppers and onions, like, you know, like that type of thing. It's just, it's insane. So thanks for bringing that up, man. I, I appreciate that you, you covering every base when I ask a question and it's, it's really nice. I do want to talk to you about the mind side. So like I said, I'm a spiritual guy. I, I really am focusing on the mind body connection and lining up our neuro side, the vagus nerve stimulation, with our health diet. But I also argue that if, if you're not really spiritually healthy, it's really hard to be overall healthy. But what is your feeling on the mind body correlation connection and bringing that all together and how do you kind of view that and look at it?
B
Yeah, the vagus nerve is a really good, perfect example. Right. So now you can use a ring or a Wristband or a chest strap to measure your heart rate. Variability is basically an indication of the vagal nerve activation of the pacemaker cells of the heart. Right? You have multiple cranial nerves, one cranial nerve. The vagus nerve snakes through the body, innervates various organs and it has branches. The sympathetic, the fight or flight, the parasympathetic rest or digest branch when working in good interplay would cause robustness of the pacemaker cells of the heart such that there is high variability between beats. Right? BA BO 1.1 milliseconds bomb 0.99 milliseconds 0.985. And if you see a low variability, that can be indication that your nervous system is kind of flat, kind of beat up, maybe stressed, in some cases over trained. So the vagus nerve, like you mentioned, is something that can play into a physical treatment of the mind body connection. Meaning that there are things that you can do to strengthen that connectivity between the vagus nerve and the heart, to strengthen the balance between sympathetic and parasympathetic. Many things people would be familiar with as coming out of like the hippie esoteric woo woo yoga world, but it would be things like meditation, chanting, singing, hummingbirds, gargling, yoga breath work. All of these do a pretty good job increasing hrv. And any or all of those would fit well and I would even say be crucial, at least present in in for some of them for an overall really good level of both physical and mental fitness. There are other newer, more technological devices that can stimulate the vagus nerve. They make electrical handheld devices like the Tru Vega or the who list that you can hold up to your neck or that kind of stimulates the, what's called the auricular branch of the vagus nerve underneath the ear. Increase your HRV within just a few minutes, which is great if you're nervous, if you are about to get on an airplane or want to fall asleep more quickly or wake up and can't get back to sleep. There are also physicians who, for people with really poor HRV and even things like PTSD who will do a stellate ganglion nerve block, which is basically like an injection of an area around the vagus nerve bilaterally on either side of the neck. And you know, that's bringing out the big guns obviously, but you can even go in with a needle and actually stimulate the vagus nerve that way. So a lot of different ways to do it, but people should be aware of the vagus nerve, the fact you can measure it and the fact that using both Kind of like ancient wisdom and modern science, you could stimulate it. And then you brought up prayer. And it's interesting because the spiritual side of things is something that probably because the fitness and health world can be so materialistic, it's not addressed quite as much. You know, not only is it something that doesn't feel immediately palatable in terms of the health effects that it produces, but it can be something that is a little bit more confusing in terms of where to start and often very dogmatic, right? Like, well, I'm going to be religious. What am I doing? Hindu, Islam, Christian, you know, like, you know, and so, you know, then that whole kind of can of worms gets opened up. No matter which way you look at it, you cannot deny the impact that has been shown in research that prayer has on health, that some type of extrinsic religious experience, like church attendance and being a member of some type of a religious body and even like group worship has on health, that intrinsic religiosity has on health, right? Belief in a greater purpose for your life, belief in an intelligence that exists outside of you, a higher being that has your best purpose in mind and even has your life, not in a robot autonomous way, but in a goodwill way, has your life kind of like planned out for you, that no matter what you're going through, you can cast your hopes upon that greater being and there actually is a plan written for your life. And if you look at religions of salvation such as Christianity, even a so called way out, right, like the ability to be able to just cast all your cares upon a figure like Jesus so you have no more guilt and no more shame and you're not expected to be good on your own, but you're just basically doing it based on the path that that deity created for you by God. Stepping out of eternity into humanity and being crucified, taking on sins, and then you're able to just cast your sins at the foot of that cross. And you know, I have books about this, like Endure and Fit Soul. I have a journal called the Spiritual Disciplines Journal. And the reason for that is that I was kind of at the tippy top of the world from a physical fitness, even a business fitness and mental fitness standpoint, like 10 years ago. But I was very unhappy on the inside. And I think I was experiencing what many, many people experience and even many ancient philosophers experience. You know, CS Lewis, Pensis, Augustine, these guys all referred to this eternal hole in the soul, this gnawing for something that's greater outside of us, you know, as a Disney Princess might say, you know, there must be something greater out there, this idea that we are created as eternal beings. And until we connect to that eternity that's outside of us, there's always that gnawing that there's something missing, something unfulfilling. And so in business, $10 million needs to become 100 million needs to become a billion. And in fitness, no matter how fit you are and whatever pinnacle that you achieve or however many ironmans you've done, like, it never quite feels like you've made it like it, like it's not as fulfilling as you thought it would be. And you could just throw anything at that eternal whole sex and money and cars and homes and fame and power. And until you actually fill the eternal gnawing in your soul with something eternal, which would be like belief in a higher power and, you know, some type of intrinsic religious experience, preferably combined with an extrinsic religious experience with, and I'm biased as a Christian, I think the most powerful of those would be like, actually like saying a prayer that to God, that you can't do it on your own. You've realized that you aren't able to do this of your own power, but that you know that God has created a way for you to achieve happiness and eternal salvation through Jesus Christ. And when you, when you say that prayer and it becomes like that simple, then all of a sudden your entire life changes. And it's not like you trying to become good all the time and trying to be better all the time, but it's as though you are equipped and enabled and supported to do the best job that you can. But there's not guilt and fear and shame over failure. Instead, it's just you being helped up by God and by that belief in Jesus to do what it is that you know you've been called to do. And then all those things like the money and the sex and the cars and the homes and the fitness, all of a sudden they actually kind of become paradoxically fulfilling, but not in fulfilling in a way that you just want to chase after more and more of them. It's like, oh, I've got enough. I can be happy now. And it's not like you lose your desire to pursue greatness or to pursue what it is you've been called to pursue in terms of just your impact here on this planet. But it feels less like grasping at straws and more like waking up in the morning happy to do the. How happy you're about to let just like roll up your sleeves and do what it is that God has put on your plate for that day. So, long story, short, long answer. I know, but I. I would say, if anything, since our bodies are going to fade and our bones are going to become porous and our muscles are going to be like beef jerky, you know, at the end of the day, that the spiritual fitness is the most important thing because your soul is like the one bright eternal spark that will go on to exist for better or worse, for eternity. That's the part you should care about the most.
A
I. Dude, like, you've. You've been so insightful and you've shared so much, but the. What you just did right there for me, and I hope for everybody, is by far and away the most impactful. You know, what you said there, if you looked at me on paper seven, eight years ago, you would have thought I was like, had it all, right? I mean, making six figures a month at three, four cars in my drive, arcade games in my h. Like, everything a dude would want, you know, shoe collection. And I'm telling you, Ben, every night I go. I'd look at my wife when I get into bed and I. And I'd just be sad, miserable, empty. Like, I felt like, what, what is it? I can't feed myself enough that I'm buying and doing. And, like, why am I just so off every day, every night? And when I really became God first and I stopped worrying about everything, just let it happen and fall into place. It'll come if it's supposed to, and if it's not. And, you know, you stop taking money from everybody, throwing at you and selling out here and there, and just doing what's good and right. Every single thing for me has fallen right into place, as it should. And now I'm doing what I was put here to do and I don't even worry about it. I don't wonder what's next or what. Nothing. I'm stressed when I get on a flight or something if I'm going to be late. But in general, that feeling that you just described is where for me, and I think for a lot of people, is it just completely changes. And that's when the whole world will open up to you and then you can really become healthy and happy.
B
Yeah, it's not. It's not a magic prosperity switch, right? No, we're not talking about, like, thinking you will grow rich, because sometimes people hear you and I talking like, oh, wait, all I have to do is, like, become religious. And all of a sudden, you know, everything Just clicks and, you know, making the money I make and getting the job going, it's not like that. Like your problems don't disappear. But what I would more accurately define it as is a contentedness switch. Being contented is not synonymous with being happy. It's not like you're just like laughing and cruising through life all the time. Being contented is essentially that feeling that no matter what, no matter what you're going through, you know things are going to get better and you're right where you're supposed to be. And all you're supposed to do is, is be in that moment, trust God and do the very best job you can without despairing. And the only way to really do that is to actually, like, know that God is on your side and have a God that you can talk to.
A
That's it. And when people ask like, how do I pray? It's really, it's just a conversation with God is all it is. And turning it over to him. One of the things that I've learned to embrace, that's very hard. And it's still hard. I'm sure you probably deal with this too is accepting like, adversity, but understanding why it happened and then seeing later on time and time again, wow, this happened because then it set me up for this or it helped me do this. It shaped my future.
B
I mean, yeah, adversity. Adversity is multimodal. Adversity can be God keeping you humble, right? Giving you some type of a health issue so that you don't become that asshole podcaster who has it all figured out and all of a sudden you go farther away from God because all of your health problems are solved and, and you're just a, you know, a walking picture of perfection. And God sometimes puts you through adversity so that you are more empathetic towards what other people are going through. Yeah, right. He, he might have a period of time where you go through financial distress just to open your eyes up to being able to help others when you have financial wealth to go around. Or he might put you through a sickness so that you're a little more willing to take flowers to somebody who's in the hospital or yes, take care of their dog or be there for them in some way. And then finally, and this is of course the age old question, I don't know if it's a can of worms or should even open up towards the end here, but I'll briefly name it. There is, you know, this idea, well, why would God allow anything bad to happen in the first place, you know, and. And some of the reasons that I've just described are the reasons. But then the last reason, and this is probably the hardest one for people to swallow, is, well, God's God, right? He made everything. You wouldn't even be alive right now if God hadn't been. He. God does kind of call the shots, right? We don't know what kind of plan God has in mind, but God certainly does. And who are we to question that? We know that God draws straight lines with crooked sticks. And that's the hard part of being about being a puny little human, is there is an intelligent being outside of you. And sometimes the way that they decide to pull off an incredible thing for the universe is not the way you would have done it.
A
Exactly. And you don't question it. And if everything was just the same every day, then what would the point of even be living if we were all the same and nothing ever changed?
B
There was.
A
There has to be failure with success. There has to be bad and good.
B
Or else what would we have? There has to be evil with free will, right? Like, you know, God could have made us little robot automatons who just, like, worship him all day, which. And don't get me wrong, that'd be great. But instead, God gave us free will, and we get to decide what we want to do. And you know what? Sometimes we make the wrong choices. And that's why there's. There's. That's why there's evil. That's where there's sin. And that's. That's why the message of forgiveness is so beautiful. That's right.
A
I know you gotta go here in a minute. I got one more for you if you can, really quick. It's a quick one. And then just want to say thank you again. I valued this. Let's do this. Your top five staple foods that you have every single day or incorporate most often in your diet.
B
How about I give you my grocery shopping list when I travel?
A
Do it.
B
That's it. Do it. Because I have, like, the whole foods grocery shopping list or even just Rosars or whatever. So let's go and do this from memory. I'm gonna. I'm gonna hit the big ones. Okay. I miss anything, it's because it's not important. So this would be like, you know, the person who says, you know. Cause I have clients who will say this sometimes. I'm like, no, no, no. They'll be like, oh, I've been traveling for the past 10 days, and I Just went off the bandwagon. You know, I've been out and, you know, couldn't find any good food. And so I typically get the Whole Foods order in once I know about when my plane is going to land. And I realize even Whole Foods is whole paycheck for a lot of people. So Instacart, Rosars, Albertsons, I don't care. You could pull what I'm about to describe to you off anywhere. The only reason I go Whole Foods is I like their chicken. So I get one whole cold rotisserie chicken that easily goes in the mini fridge. That'll give me, like, two days of protein. I get a bag of frozen blueberries, and even those in a mini fridge in a hotel room will just, like, stay good longer than the ones in the canister, and they're cheaper. I get bag or, you know, a little, whatever you call it, little, like. Like little canisters of macadamia nuts or walnuts.
A
Yep.
B
I get a few tins of either sardines or anchovies, a thing of mixed greens, cucumber, a tomato, and a little thing of mustard, which I use for the sauce with the chicken. Just like, good stone mustard. And then if I've got any money left over, I got a bar of dark chocolate. Oh, and a yogurt. I like that. I like the really good, thick, creamy coconut yogurt. Yeah. So I get all that stuff. It arrives at the hotel. Everything can fit into the mini fridge. It needs to fit into the mini fridge. I get the little utensils from the hotel restaurant or the ones that they. They put in the. In the bag, Whole foods, little salt packets and pepper packets. Even though a lot of times I travel with my own really good salt. And I can do, like, chicken salads. I can do yogurt with chocolate and blueberries. I can do, you know, chicken dipped in mustard. I can do a Mediterranean style, like, sardine salad with tomato and cucumbers on it. Like, I can do a few pretty decent meals. Any really well on what I just described to you, for everything I just said, that's still under a hundred bucks. Yeah. Any grocery store, at least in the US and many grocery stores around the world. So, you know, that that's just an example of, of how you could pull something like this off, like, be healthy even when you're on the road and everything. I just said you would totally thin to, like, a home grocery shopping list too.
A
If you. Man, if you saw the. The structure I have around my travel and food, like the cooking and the VBOs and everything I buy and what I do, and I, I even bring my own avocado, so they're right. No, I'll have to tell you sometime off camera, it's, it's messed up, but it, it, you know, it, it's just. I'm that detailed of a guy. But I think what you said, you can do this even if you're on a quick trip to a hotel. If you just do it right and take the time to map it out, I mean, you could really do it. So I'm with you, man. Look, I could go 20 more hours with you. I, I swear this was one of my favorite conversations I've ever had. I really appreciate it, man. It was, it was. You are the man for sure. And, and well, well earned all the accolades you have, and I don't think it's enough for you. So why don't you tell people? I know you got a couple new things that you've just had come out. You want to tell them about that and where to follow you. I mean, it's easy, but we'll just put it in the description.
B
Let's see. I think the coolest things for people would be, you know, I have a podcasts and the right articles and stuff. @BenGreenfieldLife.com I have a new book. It's like the bible of biohacking. It's called Boundless on Amazon or boundlessbook.com and I just, I just launched a new like, ketone based bar with, with ketones in it, which is kind of unique. I don't know of anything like that that exists. It tastes pretty good. They got cinnamon roll and vanilla cheesecake and I'm working on chocolate and that's called the boundless bar boundlessbar.com and so those would be a few things to check out.
A
Yep, I'm gonna try some of those myself. They fit right into my daily, daily diet. So I appreciate it again, brother. Thanks again. I'm gonna look forward to seeing you at events and talking with you in the future and, and I, I appreciate everything that you do and that you've done all these years and I know you got a long way to go, so thanks again for your time, man.
B
Oh, thanks, Dylan. Love you, bro.
A
Love you too, man. All right, everybody, that wraps up another one. Stay tuned for plenty more to come. Dylan Gelli and Ben Greenfield signing off.
Date: December 22, 2025
Host: Dylan Gemelli
Guest: Ben Greenfield (New York Times bestselling author, fitness expert, biohacker)
In this Christmas special, Dylan welcomes one of his most sought-after guests, Ben Greenfield—a cornerstone in fitness, biohacking, and wellness. Together, they dive deep into nuanced topics of diet, fasting, heart health, cellular well-being, spiritual fulfillment, and practical, actionable strategies for optimizing quality of life. Both share personal stories, expert insights, and advanced protocols, blending hard science with real-life experience.
[03:10 – 10:35]
Ben’s Viewpoint:
Notable Quote:
“Test yourself, self-quantify, and customize your diet to you. If you can’t, follow some semblance of a Mediterranean diet, strict carbs, but not excessively, unless you’re managing some kind of disease.”
(Ben, 10:26)
[11:51 – 19:39]
[20:39 – 36:03]
Differences between stable (hard) and unstable (soft) arterial plaque, their respective risks, and diagnostic strategies.
Importance of not relying solely on lipid panels—imaging (carotid ultrasound, calcium scan, clearly CT) provides more actionable insight.
Pharmaceutical approaches: Combination of statins, ezetimibe, PCSK9 inhibitors; discuss concerns on side-effects and cholesterol’s positive roles.
Natural strategies: High-dose nattokinase, dietary nitrate sources, red light therapy, PEMF, minerals. Notably, supplements require effective dosing (e.g., 8,000–12,000 IU nattokinase).
Dylan shares his personal cardiac journey and Lp(a) reduction from 330 to under 100.
When to start testing:
Notable Quotes:
[33:58 – 37:15]
[37:16 – 45:10]
Foundations for all health: cell membrane fluidity, dietary fats, quelling oxidative stress, mineral balance, and nature-based therapies.
Real-world strategies: Eat diverse fats (target omega-3/omega-6 ratio), embrace dietary plant diversity, supplement minerals if needed, utilize sunlight, grounding, PEMF.
Dylan shares his transition out of “fat phobia,” moving from low to high dietary fat, observing improvements in health/activity level.
Notable Quote:
“Cellular health and mitochondrial health are basically the foundational principles behind every organ system... So for the cell membrane: proper fluidity and rigidity... avoiding a completely fat-phobic approach…” (Ben, 37:59–38:15)
[47:13 – 60:31]
[61:14 – 63:51]
The conversation is rich, evidence-driven, and practical with many personal anecdotes. Ben and Dylan blend technical protocol with grounded, lived experience, while not shying away from faith, adversity, and deeper meaning. At every step, nuance and personalization—whether in nutrition, supplementation, mindset, or spiritual approach—are emphasized.
This episode stands out for its depth, actionable science, heartfelt spirituality, and mutual respect between two leaders in fitness and health.