CGM Series | The Glucose Never Lies® Podcast

CGM accuracy is usually described with a single number: MARD. But a low MARD can hide significant risk if the study behind it was poorly designed. Professor Othmar Moser — one of the leading independent CGM accuracy researchers — explains what study design actually determines, why meal and insulin challenges are non-negotiable, and what people with type 1 diabetes and clinicians should look for when evaluating any accuracy claim.

In this episode:

What MARD is and why it misleads when used in isolation
The five study design questions that determine what accuracy data actually means
Why 20/20 and 40/40 agreement rates reveal what MARD cannot
Why meal and insulin challenges are essential for real-world accuracy testing
What CE marking does and does not guarantee about CGM performance
Why peer-reviewed, independent evidence is the gold standard — and how little of what is cited meets it
How study design quality shapes what we actually know about CGM risk
Professor Moser's perspective as a researcher who designs and runs these studies

Guest: Professor Othmar Moser, Medical University of Graz, Austria. Leading figure in independent CGM accuracy study design and insulin-related exercise physiology research in type 1 diabetes.

Links:

Full show notes: https://theglucoseneverlies.com/episode-35-cgm-series-the-importance-of-cgm-accuracy-and-study-design-with-professor-othmar-moser/
CGM Guide Part 2 — Assessing CGM Accuracy: https://theglucoseneverlies.com/assessing-cgm-accuracy-performance/
CGM Guide Part 1 — How to Choose a CGM: https://theglucoseneverlies.com/select-continuous-glucose-monitor-cgm-understanding/
Episode 36 — DSN Forum: CGM Accuracy and ATTD 2025: https://theglucoseneverlies.com/episode-36-cgm-accuracy-dsn-forum/
Watch on YouTube: https://youtu.be/zTdTps42kQ8

Educational purposes only. Not medical advice. Always work with your diabetes care team.

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Collaboration: John Pemberton — john@theglucoseneverlies.com

Creatives: Anjanee Kohli — anj@theglucoseneverlies.com

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Disclaimer
This content is for informational purposes only and does not constitute medical advice.