Could depression be more than a chemical imbalance? In this episode of The Health Pulse, we explore a powerful new lens: depression as an energy crisis in the brain. This emerging field of metabolic psychiatry examines how the brain’s fuel systems—especially in individuals with insulin resistance or mitochondrial dysfunction—can directly influence mood, cognition, and resilience.

We break down how the ketogenic diet, long known for weight loss and epilepsy management, may offer mental health benefits by supplying the brain with ketones—a cleaner, more efficient fuel than glucose. You’ll learn how ketones reduce neuroinflammation, support mitochondrial repair, and help rebalance key neurotransmitters like GABA and glutamate.

From a groundbreaking 2022 study showing improved depression symptoms in just eight weeks to striking case reports of treatment-resistant depression in remission, this episode brings the latest science to light. We also share practical guidance for exploring a therapeutic ketogenic approach, including baseline testing, nutrient-dense planning, and gradual transitions.

If you've struggled with mood symptoms, brain fog, or fatigue—and feel like something deeper is being missed—this conversation might change how you view mental health.

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Disclaimer: The information provided in this podcast is for informational purposes only and should not be considered medical advice. The content discussed is based on research, expert insights, and reputable sources, but it does not replace professional medical consultation, diagnosis, or treatment. We strive to present accurate and up-to-date information, medical research is constantly evolving. Listeners should always verify details with trusted health organizations, before making any health-related decisions. If you are experiencing a medical emergency, such as severe pain, difficulty breathing, or other urgent symptoms, call your local emergency services immediately. By listening to this podcast, you acknowledge that The Health Pulse and its creators are not responsible for any actions taken based on the content of this episode. Your health and well-being should always be guided by the advice of qualified medical professionals.

The Brain's Energy Crisis: Rethinking Depression | Episode 66