
Hosted by Massively Better Healthcare · EN
🏆 2026 Webby Award-winning podcast.
Join us every Monday for conversations with the biggest names in healthcare. Hosted by health tech veterans Halle Tecco, Michael Esquivel, and Steve Kraus.
Learn more and submit your ideas for the show at the Heart of Healthcare website.

AI in healthcare may be entering a new chapter, one where the biggest question is no longer whether the technology works, but who is willing to deploy it, measure it, and take responsibility for the risk.This week, Steve sits down again with Eric Larsen to revisit his predictions from last year’s Webby-winning episode on generative AI in healthcare. Eric argues that the first wave of AI has been inflationary, reinforcing the old payer-provider payment model, but that the next wave could be deflationary as automation moves into revenue cycle, administrative work, clinical reasoning, and drug development. They discuss why incumbents still have a narrow window to co-develop the future, why clinical AI may move faster outside the US, and why liability may become the deciding factor in who wins.We cover:Why healthcare is still the sector most exposed to AI-driven changeHow AI has reinforced fee-for-service dynamics so far, and why that may soon reverseWhat makes some healthcare work more automatable than othersWhy liability may determine how fast clinical AI gets adoptedWhich health systems, payers, and life sciences companies are moving fastestWhat will change across providers, payers, and pharma over the next year— 👉Submit your questions!We’re doing a followup episode with Eric. Submit your listener questions here: https://forms.gle/Bu335DkpHAUvygiBA— About our guest:Eric Jon Larsen is President of TowerBrook Advisors and a member of the healthcare leadership team at TowerBrook Capital Partners, a $30 billion AUM investment firm based in New York and London. TowerBrook invests across private equity, structured minority, and growth opportunities, with a strong focus on healthcare, partnering with health systems, payers, and other strategics. Notably, TowerBrook is the first mainstream private equity firm to achieve B Corp certification, reflecting its commitment to responsible business practices.Eric is a nationally recognized healthcare strategist with a global advisory portfolio spanning CEOs and boards of leading healthcare organizations. He spent 25 years at The Advisory Board Company—five of those as President—advancing best practices in healthcare delivery worldwide. Following the firm's 2017 acquisition by Optum (UnitedHealth Group), Eric co-led strategic partnerships and market development efforts at UnitedHealth. He is also a Venture Partner at Thrive Capital and SignalFire, and serves on several digital health boards, including Somatus and Contessa Health.— 🙏 Do you like this podcast? An easy and free way to help keep the show going is to leave us a review on Apple, Spotify, or wherever you're listening.— 📍 Connect with us:Heart of Healthcare websiteLinkedInYouTube See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Medicaid reimbursements are shrinking, providers are pulling back, and vulnerable populations are losing access to care. Akido Labs is betting that AI can expand care capacity fast enough to reverse that trend.This week, Halle sits down with Prashant Samant, co-founder and CEO of Akido Labs, to discuss what it actually takes to scale care with AI. They explore why Akido built a full-stack healthcare company, how its AI operates inside real clinical workflows, and why the hardest patients are the best place to test whether this model works.We cover:Why he chose to build a full-stack care modelHow AI changes who can deliver care, and whereWhy most healthcare AI tools fail once they hit real clinical workflowsWhy the doctor shortage cannot be solved by training more doctorsHow the bottleneck in healthcare AI is absorption, not innovationAbout our guest:Prashant S. Samant is CEO and co-founder of Akido, a healthcare technology company that builds clinical AI and operates a multi-state medical network serving hundreds of thousands of patients. He co-founded Akido in 2015 through USC’s Digital Health Lab. In 2023, he and his co-founders received the EY Entrepreneur of the Year–Greater Los Angeles Award. Samant is also a co-founder and board member of Grid110, a nonprofit accelerator supporting early-stage entrepreneurs. He holds a bachelor’s degree in economics from Washington University in St. Louis.— Show Notes:Akido’s recently-published white paper on street medicine— 🙏 Do you like this podcast? An easy and free way to help keep the show going is to leave us a review on Apple, Spotify, or wherever you're listening.— 📍 Connect with us:Heart of Healthcare websiteLinkedInYouTube See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

AI is everywhere in healthcare, and May's big question is whether it's actually delivering. The money is flowing, the promises are bold, but some cracks are starting to show.Steve and Michael break down the month's biggest stories.We cover:Digital health hitting its strongest funding quarter since the pandemic peak, and why deal concentration tells the real storyHow Medvi built a billion-dollar GLP-1 company on fake doctor profiles, fake reviews, and a drug with zero bioavailabilityWhy AI in prior authorization and billing may be inflating healthcare costs rather than cutting themThe peptide craze: what the science says, what regulators have banned, and why Michael is actually taking oneHow AI could collapse today's narrow medical specialties into a "generalist specialist" modelNew research showing Epic's out-of-the-box AI models fall short on real-world clinical benchmarks—Show notes:Rock Health Q1 2026 Funding ReportNYT Profile of Medvi + Futurism InvestigationPeterson Health Technology Institute: Administrative AI ReportSTAT News / Undark: BPC-157 and the Peptide CrazeHealth Affairs Scholar: Kocher & Wachter on the Generalist-Specialist ModelSpringer Nature / Journal of General Internal Medicine: Epic AI Model Meta-Analysis— 🙏 Do you like this podcast? An easy and free way to help keep the show going is to leave us a review on Apple, Spotify, or wherever you're listening.— 📍 Connect with us:Heart of Healthcare websiteLinkedInYouTube See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Forty million people use ChatGPT for health-related questions every day, making it one of the most widely used tools for health information in the world. So what is their team doing to maximize impact and minimize harm? For one, they've brought in hundreds of physicians globally to continuously review outputs and shape how the models respond across different scenarios, literacy levels, and edge cases. Second, they've hired my Rock Health co-founder, Nate Gross, MD, as their VP of Health.In this full-circle episode, I sit down with Nate, who also co-founded Doximity (DOCS) and knows a thing or two about building in digital health. We discuss the astonishing speed of AI progress, how models are trained for safety and accuracy, and what this technological evolution means for every part of the healthcare system.Key topics:How ChatGPT is becoming a 24/7 front door for health questions, and whether it is replacing Dr. Google or starting to compete with the healthcare system itselfHow OpenAI is trying to reduce hallucinations, avoid sycophantic behavior, and build guardrails for sensitive use cases like mental healthOpenAI’s goals to “raise the floor, sweep the floor, and raise the ceiling” with new product launches like ChatGPT for Clinicians and GPT-RosalindHow Nate thinks about the AI race and what winning in healthcare actually requiresWhere startups should focus their efforts now that specialized products are launching for clinicians and life sciencesThe single hardest problem in healthcare that AI, according to Nate, probably won't fix anytime soon— About our guest:Dr. Nate Gross is the VP of Health at OpenAI. He previously co-founded Doximity and Rock Health. He graduated from the Emory University School of Medicine with an MD, Harvard Business School with an MBA, and Claremont McKenna College with a BA in Government. He serves as affiliated faculty for the Clinical Informatics Fellowship at Stanford.— Show notes:ChatGPT for CliniciansChatGPT for Health (for patients)OpenAI for HealthcareGPT-Rosalind— 🏆 Thank you for your votes! We're excited to share that the Heart of Healthcare is a Webby Award Winner for 2026!— 📍 Connect with us:Heart of Healthcare websiteLinkedInYouTube See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Nearly one billion prescriptions are abandoned at the pharmacy counter every year, often because patients are blindsided by the cost.This week, co-host Halle Tecco is joined by Wendy Barnes, President and CEO of GoodRx, to discuss the chaos of prescription drug pricing, the murky world of Pharmacy Benefit Managers (PBMs), and how digital tools are changing patient affordability. They break down the layered system of manufacturers, payers, and pharmacies that creates inconsistent pricing, and explore the current push for greater transparency.We cover:The cascade of drug pricing: from initial manufacturer costs and rebates to payer and pharmacy contracts, which results in vast price variability for consumersWhat it would take to get to price transparency in drug pricingThe current pressures on PBMs, including efforts to ban "spread" and the practice of offshoring rebate contracting for tax advantagesWhy pharmacies haven’t gone online like other areas of consumer goodsThe future of medication access, including the growth of pharma’s direct-to-patient programs and the low current adoption of home delivery despite widespread retail pharmacy closures— About our guest:Wendy Barnes is the President and CEO of GoodRx. She has over 30 years of leadership experience across the pharmacy and medical benefit industry. Most recently, Wendy served as CEO of RxBenefits, where she led the company in providing pharmacy benefit support to more than 2,000 self-insured clients, representing over 3 million lives. Prior to that, she served as President of Express Scripts Pharmacy, overseeing operations for 100 million beneficiaries. Her leadership spans roles at Rite Aid, Premier Inc., and the U.S. Air Force, where she served as a Medical Service Corps Officer. She holds a B.S. degree in Biochemistry from the United States Air Force Academy and an M.B.A. degree from the University of Alaska Anchorage.— 📍 Connect with us:Heart of Healthcare websiteLinkedInYoutube See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Pete McCanna, CEO of Baylor Scott & White Health, believes that health systems are built around the wrong objective… and he has an ambitious goal to change that.This week, Halle sits down with McCanna to unpack how one of the largest and most successful health systems in the country is shifting from a supply-driven model to one built entirely around the customer. They discuss why legacy systems operate like “walled castles,” what it takes to redesign care around real conditions instead of departments, and how Baylor Scott & White is testing a model that prioritizes access, personalization, and long-term trust over short-term profit.We cover:Why most health systems are structured to fill capacity, not create value for patientsThe reason why he uses the term "customer" instead of "patient" (and how his colleagues initially responded)How loyalty and trust make it economically sound to offer services that lose money.The strategy for deploying AI to create product differentiation for patients rather than just improving internal efficiencyThe limits of the “payvider” model and why it’s harder than it looksThe three healthcare laws he thinks need to be rewritten—About our guest: As CEO of Baylor Scott & White Health, Peter (Pete) McCanna is focused on empowering customers to live well by reimagining traditional healthcare—offering more convenient, personalized, and informed experiences. He is leading Baylor Scott & White’s customer-centric transformation by bringing together the system’s 59,000 team members around a common goal to keep people healthy and feeling connected and supported.Before becoming CEO, Pete served as the health system’s president. In that role, he drove operational excellence, strengthened clinical alignment, scaled the system’s digital health platform, MyBSWHealth, and deepened academic partnerships to address the critical need for healthcare professionals.Pete has nearly 40 years of industry experience. As executive vice president and chief operating officer at Northwestern Medicine, he exceeded targets for operating revenue, quality, patient experience, and employee engagement, making it one of the top 10 academic health centers in the country.Known as a thoughtful and innovative leader, Pete formerly served as chief financial officer at New Mexico-based Presbyterian Healthcare Services and the University of Colorado Hospital.Passionate about transforming healthcare, Pete was named one of Modern Healthcare’s “100 Most Influential People in Healthcare.” Driven by a deep sense of purpose, Pete currently serves as the inaugural board chair of Longitude Health, an innovative healthcare collaborative, and as a board member of University of Michigan Health, Texas Hospital Association, and Catholic Extension. He holds a master’s degree in Public Affairs at the University of Texas at Austin and a bachelor’s degree in English from the University of Michigan.Baylor Scott & White Health is the largest not-for-profit health system in the state of Texas. It includes 55 hospitals, more than 1,300 access points, a health plan, a research institute, and an accountable care organization, plus Levanto—a company offering digitally-enabled health solutions—and 3.5 million customers connected through MyBSWHealth.—Snow notes: Visit BSWHealth.com to learn more.Download the MyBSWHealth app.Explore Levanto.Health to learn about employer solutions built on Baylor Scott & White's digital platform and care model.—📍 Connect with us:Heart of Healthcare websiteLinkedInYoutube See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

We’re back with our monthly rundown of the top headlines in health tech!Today, Halle flies solo to share the biggest stories that shaped Q1, from the rising pressures on PBMs to how consumers are using AI.Stories covered:What's happening to PBMs (it's not pretty)New data from Rock Health on consumer use of AISocial media companies find liable for addictive designHealthcare hiring is slowing as efficiency becomes the focusHave we finally bent the healthcare cost curve in the United States?—The Heart of Healthcare podcast was nominated for a Webby award! We'd so appreciate if you could create a quick account and vote for us here. —📍 Connect with us:Heart of Healthcare websiteLinkedInInstagramYoutubeSee Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Last year, his independent pharmacy spent $13 million on brand-name drugs for patients processed by the three biggest Pharmacy Benefit Managers (PBMs) which earned a profit margin of 0.01%.In this episode, Halle speaks with Alec Ginsberg, owner and fourth-generation pharmacist at C.O. Bigelow, the oldest surviving apothecary–pharmacy in the United States. Alec is fighting against the forces squeezing independent pharmacies and charting a course for the future of the pharmacist.We cover:How the roll-up of PBMs, health plans, and retail pharmacies changed everythingWhat led him to remove his pharmacy’s Rx-filling robotThe dramatic decline of independent pharmacies along with the closures of big box pharmacy storesThe one health policy he would put in place today to save independent pharmaciesThe history of the pharmacist's role and what’s nextWhat he really thinks about compounding pharmacies and the Hims vs. Novo lawsuit—About our guest: Alec Wade Ginsberg is the fourth-generation pharmacist, owner, and Chief Operating Officer of C.O. Bigelow Apothecary, America’s oldest pharmacy, founded in 1838 and still operating in New York City’s West Village. With a Doctor of Pharmacy degree from the University of North Carolina Eshelman School of Pharmacy, Alec bridges the clinical world of pharmacy with the realities of modern consumer culture.At Bigelow, he oversees the brick-and-mortar beauty retail and pharmacy operations, navigating everything from prescription drug shortages to the pressures of today’s PBM-dominated marketplace. Beyond the counter, Alec is the founder and writer of Drugstore Cowboy, a weekly newsletter that dissects the intersection of drugs, business, and consumer culture — making the hidden mechanics of the U.S. healthcare system both understandable and entertaining for thousands of readers.His work has been featured across national media, and he’s become a trusted voice for translating complex pharmaceutical issues — from GLP-1s to compounding to drug pricing — into plain English. Alec’s mission is simple: to make Americans smarter about the pills in their cabinets and the system that puts them there.—Show notes:Drugstore Cowboy - Alec’s free and super interesting newsletterC.O. Bigelow - The Nation’s Oldest ApothecaryVirtual GLP-1 startups: Pill mills or the future of obesity care?—📍 Connect with us:Heart of Healthcare websiteLinkedInInstagramYoutube See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Chris Klomp, Director of Medicare and Deputy Administrator of CMS, and Senior Advisor to HHS Secretary RFK Jr., has big ambitions to reshape how healthcare works in the United States.This week, Steve sits down with Klomp to discuss how his experience as a digital health entrepreneur is guiding his current role overseeing a roughly $2 trillion department. Klomp shares the government's strategy for restoring trust between providers and payers, driving down costs, and addressing a system where approximately 90% of healthcare dollars are still spent in a fee-for-service arrangement. We cover:Why 90% of US healthcare remains fee-for-service after two decades of reform.The intentional design of the new Access model to be deflationary and fuel entrepreneurship among insurgents.The commitment from the payer industry to make prior authorization invisible to patients and providers by 2027.CMS's aggressive stance on data interoperability and funding enforcement against data blocking.How the Most Favored Nation policy is re-wiring global prescription drug supply to lower prices without compromising innovation.—About our guest: Chris Klomp is the Director of Medicare and Deputy Administrator of CMS, and Senior Advisor to HHS Secretary Robert F. Kennedy Jr. With extensive experience in healthcare payment reform and data sharing, he built and led Collective Medical, the largest U.S. real-time care collaboration data network, acquired by PointClickCare in 2020. There, he partnered with health systems, plans, providers, post-acutes, and state governments to advance value-based care through enhanced data access and insights.Chris has driven healthcare reform at state and federal levels, focusing on value-based care and interoperable health technology. Through Endurance Companies, a San Francisco-based multi-family office he co-founded with Stanford classmates, he has co-founded, invested in, advised, and served on the board of many innovative healthcare organizations, including Nomi Health, Maven Clinic, InnovaCare Health, and Health Joy. He also served as a Utah Senate-confirmed commissioner of the Utah Digital Health Services Commission, where he focused on leveraging technology for cost-effective, healthier outcomes. Previously, he was Vice President in Bain Capital’s North American Private Equity group and worked at Bain & Company. Recognized as Utah Business’ CEO of the Year and EY’s Mountain Region Entrepreneur of the Year, Chris holds a B.A. with honors in Economics and English from Brigham Young University and an MBA from Stanford.—🙏 Thank you to our show sponsor, Quickstudy PR, story brokers for leading healthcare executives. Learn more about quickstudypr.com.—📍 Connect with us:Heart of Healthcare websiteLinkedInInstagramYoutube See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

This week, Halle and Michael sit down for a special in-person listener Q&A to answer a range of founder questions you submitted.Topics include:What investors are prioritizing right now and how first-time founders can stand outHow to think about board seatsWhat to do if your growth has plateauedThings to keep in mind when negotiating a health system contractHow to think about choosing between small funds and mega-VCsWhat “pay to play” really meansHow to handle co-founder equity when someone leaves early—📍 Connect with us:Heart of Healthcare websiteLinkedInInstagramYoutube See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.