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Dave Asprey
You also do the enhanced protocol, so I had that done as well. And guys, if you're shocked, I've had stem cells injected in my eggplant multiple times in the past. Talk to me about the procedure that you did on me.
Dr. Urzola
Basically what we do is we use shockwave therapy to induce microtraumatisms in the cavernous bodies of the penis. We were doing this on people who were refractory to pharmacological treatments. So people that were on Cialis or Viagra and wouldn't get ere even if they were using these drugs. Around 52% of these patients refractory to medication started to get functional erection. Basically the idea of this is that by inducing these microtraumatisms in the thylum of the cavernous bodies and then injecting in that specific area under ultrasound guidance. Also, you know, the msc, they also
Dave Asprey
reported a change in diameter. I noticed a very substantial difference in length, especially from doing multiple treatments that way. It was kind of ridiculous. You're listening to the Human Upgrade with Dave Asprey.
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Dave Asprey
this is a special episode of the Human Upgrade, recorded in Costa Rica with my friends at rmi, which is a stem cell and longevity clinic. And I'm doing this episode because, well, I've been into cognitive function. It's one of the big parts of biohacking. It's how you make your brain work the way you want it to. Work because that's also part of being more aware and more conscious. And he wants to live a very long time. If you put your car keys in the fridge and you don't know your name. So cognitive function is one of the most precious things that you can preserve as you age, or maybe as you don't age, but just the calendar or some that's goal. So our guest today is Dr. Urzola, who's been on the show today. So Our guest is Dr. Urzola, who's been on the show before, and he's a co founder of rmi, the clinic that I'm at right now. You might have heard me mention on a couple other episodes that I've done the brain upgrades and this is a hardware upgrade. The predecessors of what I'm doing this week, and this is where you could do focused ultrasound in order to get stem cells into your brain. And they've radically changed the program. And I'm to the point now where I would tell you 40 years of Zen is the best software upgrade for your brain that I'm aware of right now, which I do in Austin. And RMI is the best hardware upgrade for your brain because your hardware isn't working. It's hard for your software to work. And if your hardware is working, it's so much easier to do the healing work. So it's kind of a chicken and egg situation. But let's talk about bringing hardware into this episode. Dr. Ursola, good to see you again, my friend.
Dr. Urzola
Thank you for being here. It's a, it's a pleasure to have you again and I'm very excited to have this opportunity to tell a little bit our your audience. You know what we're doing here.
Dave Asprey
Tell me about the cognitive protocols. Like where did they start and where are you today?
Dr. Urzola
The cognition protocol is a protocol that we developed using a group of doctors, including two neurologists and a neurosurgeon. And we basically start using technology that is already available worldwide. It's FDA approved. And basically we use a neuronavigator, we do a functional mri so we can understand exactly which areas of your brain are hypofunctioning or malfunctioning. And this gives us an anatomic position for these areas that are not working. Okay. So we use markers that we place in your skull. Okay. The optical tracker sees these markers and understands the position of your brain. Okay. And then based on this, we can direct transcanadial magnetic simulation and a focus ultrasound to specific areas of your brain being super, super you know, accurate. We're speaking about millimeters here. Okay. And this allows us to basically reboot neurons to the right voltage of their membranes. And also it allows us to open the blood brain barrier so we can, you know, allow cells to do the diapidasis process into the areas where we want the. The cells to arrive. And we're basically combining mesenchymal stem cells from umbilical cord, which, as you know, are really good controlling inflammation. Most of these, you know, neurological conditions have a very important neuro inflammatory component. And then we use mu cells which are much more pluripotent and they target an SP1 receptor. They basically look at that receptor in the cells that are not. Okay. They phagocytize the cell, so they eat it, you know, and remaining remaining DNA pieces of the cell they ate, you know, basically tells them what identity to take, so they take over that cell and replace it. And so we tested this for a long time using, you know, different probes at the be. Probes were not arriving quite where we needed them to arrive. So we started upgrading and upgrading the protocol until we finally got it together. And now the results that we're getting validated with scales are really, really, you know, amazing.
Dave Asprey
Well, I did the grandfather of this when you were developing the protocol and we didn't have the MRI of my brain, so you were using just blood flow, but you used the focus ultrasound, hyperbarics and your stem cells on my brain. And it felt like going from like normal resolution to 4K. It's like, oh, wow. I really noticed a difference. Quite a surprising one actually. And with the experience I've had so far today, I'm just at the beginning of the Brand protocol. The addition of the very powerful focus magnet, where you can feel it come inside your head doing something, even though it's just outside the brain, but it's kind of stimulating inside the brain and the focus ultrasound, it. It feels really different. And I'm really excited to see how this comes out.
Dr. Urzola
Yeah, well, you know, at the beginning we were using anatomy, basically use, we know the, the anatomy of the vessels of the brain. So with a Doppler device, we could tell which vessel we were, you know, near to. And then we were trying to direct this, you know, ultrasound to that vessel. Okay. So it would work, but it was not as accurate as what we're doing right now. Right now it's like, you know, I mean, we, we can go to a specific vessel, target the vessel, and open that specific area of that vessel that we want to open. So this is really, really cool.
Dave Asprey
It's crazy to see my brain. And I'll put some of the videos in here so people can see it. But I was recording this and. And you can just see, okay, I'm. I'm wearing stuff on my face. That's the magnetic markers. And then you look on the screen and you can really see inside your brain with fine detail exactly where you're going and what the shape of the field will be. It's. It's like something from the future.
Dr. Urzola
Yeah, no, it's really, really cool. And it's very fun also, because, you know, when you're doing this protocol, we can tell you, okay, Dave, we're going to make your thumb in your right hand move, and we can target the area, and then your thumb starts to move, you know, and this is how accurate, you know, these devices are. Um, and of course, you know, once we were able to accomplish this accuracy, then there was the other part in this. We have a lot of experience already in how to really combine cells to accomplish, you know, a better therapeutical effect. This is really important. Sometimes people say, oh, you know, I got 100 million cells. You know, sometimes the doses, you know, is not related to how many cells you use, but to using the right amount of cells and putting them in the right place, you know, and then, you know, these combinations that we're doing now with the umbilical cord cells and immune cells are working really, really well, and it's making a difference. And what's really interesting is that because we're using validated scales, you know, so to measure cognitive function or to measure depression or anxiety. Okay? The. The interesting thing is that when we treat patients, the three scales, you know, on different, you know, for different purposes, show improvement. Okay? So. So this is really, really. I mean, I think it has a lot of value because you're using three different methodologies that have been accepted by a scientific community. And with the three scales, we're consistently seeing improvement in the patients and also the clinical outcomes. You know, we've started to treat some people with dementia and patients who were incapable of dressing, you know, or doing their. The buttons of their shirts after, you know, 15 days, more or less of the treatment, start to be able to dress themselves and do it, do it, doing, you know, things that they couldn't do for years. So these, of course, you know, we're at the beginning. And, you know, I am a plastic surgeon. I was brought up in a very orthodox system like most doctors, you know, and I would still say we're in an area of anecdotal, you know, cases. We need to increase the number of people we're treating with these protocols so we can run, you know, proper statistics and confirm sign, you know, statistical significance. But I always tell people, by the same token, you know, it's always anecdotal until it's your mom that you treated and she improved. Right. So at least, you know, something very important is the patients we've treated so far, 100% of them have shown important clinical improvements. And this, of course, gives us a lot of hope and encourages us to keep on treating patients and see and collecting the data to. To validate these results with larger numbers.
Dave Asprey
Okay. So sometimes people accuse me of not knowing how to dress like an adult. So is this going to help me with that?
Dr. Urzola
He might, you know, but I don't
Dave Asprey
really have anything wrong with my brain other than that I'm pretty weird. So I'm interested in having it work even better than it does now. How does the cognitive protocol compare to that?
Dr. Urzola
Well, you know, by improving your cognitive. Your cognitive function, you know, your brain is definitely going to work better. You know, like, I'll give you a good analogy. When you have a muscle inflammation, your muscles don't work as well, or where when your joints are inflamed, they don't work as well. We have already really well proved that we can control inflammation and improve function with scales in joints. You know, and like I was saying yesterday, the brain, you know, also is an organ that can get inflamed. And when you have, you know, neuroinflammation, your brain is not working as well. Okay. So These combinations of TPEs and the neurocognitive protocol with these devices that now we have really make a difference in your brain's physiological functions, and this is why the scales improve so significantly.
Dave Asprey
Wow. So will IQs possibly go out?
Dr. Urzola
Well, that is a really hard to answer question. Okay. I think that when your brain works better and you have better focus. Okay. You tend to learn better and you tend to solve problems better. Okay. But for me to be able to tell you that your IQ is going to go up, I would need to do a trial where I test your IQ with the same methodology before and after the treatment to measure those differences. Proven it.
Dave Asprey
But if you were to bet. What were you saying?
Dr. Urzola
Yes, if I was to bet on it, yes. Yeah, yeah.
Dave Asprey
And I respect that. You know, we think it's going to work this way, but we're going to prove it before we make the claim.
Dr. Urzola
This is something that I, that, I mean, I have been super, super strict about this with the company since the very beginning. And so has Dr. Rojas, you know, who's the medical director, and so has Dr. John Papa, who's the other founder. We really want to make sure that what we are doing is, you know, safe, number one, and that it has efficacy and it is replicable, you know, and, and this is something that's, you know, important. Now we have a lot of papers that are, you know, coming up with important numbers in data, you know, and, and with percentages that are really good again using validated scales. Everything we've done is like that so far. We have a perfect track record in safety, which is really good after five years of, you know, treating, you know, thousands of people. And, and I think this is really important. It's also due to us always trying to apply this scientific method in what we're doing.
Dave Asprey
I love it. I've been down four or maybe five times to rmi and I referred a lot of clients from Unlimited Life, which is my concierge longevity program for VIPs. And so many of our members have come down and had really powerful experiences. So I'm a big fan. And you're the only place on earth that does this cognition product all the way. You're describing it right now and it's really cool. So I've just done my first day of it and I can't wait to finish it. So this is cutting edge biohacking and neuroscience. And guys, if you're into brain longevity or you've got some stuff wrong with your brain, it's daveasprey.com RMI and just go there and look you up and there's a special package for you that gets you all the stuff.
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Dr. Urzola
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Dave Asprey
Now, I mentioned this on our last episode, but when you come down here, you can do some other stuff. Like I just did plasmaphoresis. Today I had four liters of my plasma, this big bag of yellow stuff. And I'll show you a picture of that as well. Talk to me about plasmapheresis and its role in longevity.
Dr. Urzola
Well, I love to explain this so that everyone can understand it very easily. Like, you have a fish trunk, okay. And the skin is the glass of your fish tank. The fish are your cells, and the water in your fish tank is your plasma. Okay? So, of course, if this water is dirty, your fish don't live as well. Okay, plasma phrase is basically cleanse the water of your fish tank. 60% of our body weight is liquid. And we basically remove all the liquid in your. In your. In your body and replace it with new liquid.
Dave Asprey
All the liquid in your blood anyway, not in your body. Right? Well, liquid inside all of your cells.
Dr. Urzola
Yeah. Like, you know, you have several compartments. You have the intravascular comp, which holds blood with liquid, of course. And then you have the interstitial space, which is that space between, you know, cells, which is, you know, basically we're swamped. Okay. And basically we remove all that water and then also replace albumin because you tend to lose a little bit of albumin. And all the. All that, you know, brownish, you know, stuff that you see in those bags is actually pro. Inflammatory mediators and toxins that we're basically removing from your system. Exactly. So it's like really a very, very thorough, important cleanse of your body.
Dave Asprey
I like to do that about once a year. Is that a good schedule?
Dr. Urzola
I like to do it two or three times a year.
Dave Asprey
Wow.
Dr. Urzola
Yeah.
Dave Asprey
Okay.
Dr. Urzola
I just feel amazing after I do it. Look, I'm turning 49 years old in a couple months in April. And. And when I do these plasma freesis, you know, I just, you know, I just feel great afterwards, you know, like, I feel like, I mean, when you get rid of all this inflammation in your body, you. I mean, you just function better. And, you know, I have a very busy life. I'm still, you know, super active in the plastic surgery world. I do surgeries every day of the week except for Wednesdays that I work here in rmi. It just makes me function better. You know, inflammation is not something nice to have around, so this really helps to get rid of it. And there's ample information that's being published on all the benefits this produces.
Dave Asprey
That's something that recently a lot of people have been talking about it and I think I did it first six years ago here maybe, and it's. Yeah, whenever I can. And there's something called eboo, which is not the same thing, that has some kind of similar benefits, but not nearly as powerful. And having done both, the full protocol you do here, that's something I recommend people do. And then you also do orthotic stem cell treatment. So basically anywhere that's been injured. So I had you guys inject my knees and ankles, which are in weak points for me forever, and they're way better than they've ever been, but I like to keep them strong. So just did that as well. And then of course, face and reproductive. So talk to me about what you see with orthostem cell procedures at rmi.
Dr. Urzola
Okay, so the first thing that, that I think is really important is the screening process that we do. Okay. There are some people that are not good candidates for stem cell orthopedic procedures. And we're very honest in that. If you're not a good candidate, you know, and you're not going to benefit, then we'll tell you. Look, there's very little chances that you get benefit when you're a good candidate. The approach that we've taken is very interesting because we do really a 360, you know, approach to joints. You know, we look at your MRI and then we do a high sensitivity ultrasound screening. So we see injuries in the muscles, in the tendons, in the ligaments. You know, we can tell how much cartilage is left in your joint and also the quality of your bone. Okay. So basically with these procedures, you're going to get a direct injection of a combination of umbilical cord MSEs, the MU cells in Pineal, almost all those structures. You know, they all need to be functioning well for you, to keep a good joint, just not the cartilage. Right.
Dave Asprey
Yeah.
Dr. Urzola
And we also started doing, I think, a little over, like around two years ago, more or less. Basically, we under fluoroscopy, we drill a little hole in your bone and we put the cells right under the growth plate of cartilage. Okay. So, you know, it's very interesting because we're. We are evolving this and seeing the images of these patients and the bone damage that was there, you know, starts to change, you know, and improve significantly. And we're starting to see some patients that are starting to improve the quality of their cartilage. And I wouldn't say that this is going to regenerate cartilage because that's a big claim to do. But I, like we were saying before, I bet it's going to really improve that. And what's really interesting is that I can tell you data, in around 8,000 joints that we studied, 82.5% of people get an improvement in their function and in the pain control with one treatment, and around 93% get improvements in function and pain control with the second treatment. So. So it's really, really good numbers on a very large number of cases. Right. And, you know, this, you know, has been published. We just, we just had a paper accepted in a journal for a study that we did on shoulders with a very consistent results in these percentages. So this is, you know, something very, very interesting. Of course, as you know, we. Before we give you the cells, we have our own lab. So we measure quantity and viability around 10 or 15 minutes before we inject the cells. So we know that the quality of the product that we're given is really, really high quality. And this makes a big difference.
Dave Asprey
Yeah. A lot of the stem cells that you can buy just at some random clinic, they might be 10% alive. You don't really know. But you're making them here, which is a different, different animal attack.
Dr. Urzola
Yeah, we make them, we freeze them, and then when we're ready to use them, we thaw them, we run them through all the lab process, including, of course, endotoxins. So we know that we have a really clean product with the right validity. So we can tell you, okay, we gave you 25 million cells and we injected in this specific point, or we gave you 50 million cells with a viability that is around 90 to 95%. And this, you know, allows us to, if you were to speak on the pharmaceutical world, accomplish a good biodisponability. Okay. Which, you know, of course, renders a better therapeutical effect.
Dave Asprey
So the ortho stuff is very powerful. But you also do the enhanced protocol, so I had that done as well. And, guys, if you're shocked, I've had stem cells injected in my eggplant multiple times in the past, and I've done whole episodes on that kind of a thing. No, I don't track my erections every night because I think that that's kind of a little too much. Not. Not my thing. But I will tell you, they do happen. So talk to me about the procedure that you did on me.
Dr. Urzola
So basically, what we do, and this is an idea that we got from Dr. Mo Kara in Houston. And basically what we do is we use shockwave therapy to induce microchromatisms in the cavernous bodies of the penis. Was very interested. Interesting is when we started to test this, we were doing this on people who were refractory to pharmacological treatments. So people that were on Cialis or Viagra and wouldn't get erections even if they were using these drugs. Okay. So we started doing this on them to see if there was really an improvement. And around 52% of these patients, refractory to medication, started to get functional erections.
Dave Asprey
Shockwave works for Ed. Absolutely.
Dr. Urzola
Yeah. So, like, around 22 days after the procedure, and this is very valid, I think, as a methodology, because people were not getting, you know, functional erections. And notice I say the word functional because that's really important. You can get erections, and they might not be, you know, hard enough for, you know, to. For you to be able to have active intercourse. Right. So these are erections that were a good quality, you know, for people to perform sexually.
Dave Asprey
Those are like violin erections.
Dr. Urzola
Exactly.
Dave Asprey
Okay. Just. Yeah, sorry. Actually, I'm not really sorry. Violin.
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Dave Asprey
It's true. It's okay. Your mom still loves you. Keep going.
Dr. Urzola
So that was fun. So basically the idea of this is that by inducing these microtraumatisms in the, you know, endothelium of the cavernous bodies, where. And then injecting in that specific area under ultrasound guidance also, you know, the mscs. And this, of course, is a procedure done by a specialist in neurology that works with us, you're basically inducing this little trauma for cells to nest there, you know, and generate a niche where they improve the quality of the endothelium. As, you know, for you to have an erection, you need to have some muscles that get, you know, parasympathetic stimuli. This is a bulbo Cavernous and iscavernous muscles, they get tight, and they basically block the exit of blood from your penis, you know, and those muscles are also worked on. So this is why I think this, you know, protocol works so well.
Dave Asprey
So you're doing shockwave and you're also putting stem cells directly in, right?
Dr. Urzola
Yeah, exactly. So if you don't have, you know, a real, you know, ED problem. We also tested this, you know, and patients reported an important improvement in the quality of their erections and. And the timeframe of the erections as well.
Dave Asprey
Didn't they also report a change in diameter?
Dr. Urzola
Well, you know, when you are able to hold the exit of blood, there should be a little bit of increase in the diameter. We really didn't measure that, you know, but some patients also reported that, you
Dave Asprey
know, I noticed a very substantial difference in length, especially for doing multiple treatments that way. Yeah, it was kind of ridiculous. So, by the way, you ever see on a. On a ruler, how it says like in and CM on a ruler? Yeah. Right. So it turns out IN stands for incorrect measure, and CM stands for correct measure. So when it says six on the correct measure, it's the incorrect measure that says, this is fit. You heard that? Yeah. This is a common problem in scientific things. All right.
Dr. Urzola
And something very. Something very interesting. You know, this is like the story of the only animal, okay, that grows after it's dead, you know, is fish. You know, that was politicians, because, you know, fishermen always say, oh, I caught a fish this big. Right. So. But no, going back to the ED thing, something very interesting is we started also treating women with this.
Dave Asprey
I was gonna ask for other than.
Dr. Urzola
And we call this the, you know, perimenopausal syndrome, you know, which affects a lot of women. And this produces problems with mucosa of their vagina. So we basically use a laser technology to induce that thing, mycotraumatism in the vagina and then do it direct injections. This is, of course, again, done by a specialist in gynecology and obstetrics. Right.
Dave Asprey
You're asleep for it, so.
Dr. Urzola
And of course, you're under IV sedation, so you don't really experience any pain. And then we inject the stem cells, you know, directly into the mucosa. And, you know, women have reported important, you know, improvement in the. In the lubrication of their. Of their vagina.
Dave Asprey
It's more than just the lubrication because you're causing growth of new blood vessels.
Dr. Urzola
Yeah.
Dave Asprey
So there's a sponginess and a lubrication. And I was with someone who had stem cells vaginally before and after. And it was not the same vagina. I mean, completely different. Like, it's part of a words to it. But yeah, it just didn't. It didn't go the same order, you
Dr. Urzola
know, and also, rejuvenation is incredible. Yeah. And also the laser, you know, that we use has already been validated to, you know, improve the tightness, you know, so that also will improve. So, you know, you basically an overall improvement of the function. And I think it was just really fair that if we were helping men, we should help their wives as well. Right.
Dave Asprey
So, yeah, anytime there's a couple in unlimited life, if one of them is going down a libido path, you might want to have your partner go with you because you don't want to create a mismatch. Well, and then there's the facial stuff that you do as well for cosmetics that are stem cells. So I did that as well, if you can see it on the camera or not. But you're doing stem cells in the face. And what I like about coming down to RMI is that, look, I'm gonna get knocked out, so I might as well get everything injected all at the same time, including my face. And I will tell you, stem cells in your face are one of the most painful injections. They really hurt, but when you're asleep, they don't hurt at all.
Dr. Urzola
No, they don't.
Dave Asprey
You guys injected stem cells and laser in my face for me, which will keep me looking young, right?
Dr. Urzola
Yeah. Well, of course, Dr. John Papa and I are plastic surgeons. And we needed to do something. Plastic surgery actually published a paper some years ago that we call the stem cell facelift, where we were doing facelift and then injecting stem cells with fat grafts, you know, and. And that worked pretty well. But skin quality is a big issue, you know, so basically we started doing this protocol with needles and video frequency to induce some trauma in the deep and superficial dermis. Because we do this in different levels. Okay. And then we do like, mesodermic injection of the stem cells in all over the place. You know, basically the same thing happens. You know, stem cells will seek for those injury sites. They will nest there and start generating a niche, you know, that basically epigenetically reprograms the resident cells to behave better and work better, you know, and this is why the, you know, skin improves so much. And of course, we use a vishadi eyes to take before and after pictures to validate these results.
Dave Asprey
Well, that's that's what I'm doing down here, guys. I did my face, my dick
Dr. Urzola
and
Dave Asprey
most importantly my brain and my knees and ankles and it takes about five days to do everything when you're down here and that's a pretty aggressive schedule. And this is one of the highest end stem cell clinics on on the planet. So it is an expensive treatment, but it is at the cutting edge of longevity. So doctor, thank you for working to co found RMI and for inviting me down again. And I've sent so many dozens of friends and clients from Unlimited Life down to work with you. The brain protocol you've got now is so good. The idea of just getting perfect hardware and then optimizing the software layer with 40 years of Zen, it's next level. So thanks for your continued innovation.
Dr. Urzola
No, my pleasure. It was always nice to have you here and I'm very happy that you're having a good experience and also that the people that you're sending are getting these good experiences and good results with what we're doing. We're working very hard to keep on developing this and making sure that the therapies we're giving are really top of the line and that people are getting a real benefit from them.
Dave Asprey
Davesprey.com RMI is where you can go to find more info about this and if you don't want to do that, that's cool. Understand that the things that we're doing here, the things with unlimited life or 40 years as end, some of it's really expensive. These are cutting edge or bleeding edge therapies and we're showing what's possible and all of these percolate down so that if you wait five years or 10 years, these will be much more widely available because we're showing that you can do it and that's part of this. And if you're saying, well, I want to do biohacking right now, well, there's a low cost way. You can go to Axo Health, which is my AI lab testing platform, or you can go to an upgrade labs that's near you and for 2, 300amonth you can get access to all the biohacking gear that I use for longevity. So I'm working to make this available for everyone. And some of this stuff is just really cool science fiction. That's what we're doing here. See you next time on the Human Upgrade Podcast.
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The Human Upgrade, formerly Bulletproof Radio, was created and is hosted by Dave Asprey. The information contained in this podcast is provided for informational purposes only and is not intended for the purposes of diagnosing, treating, curing or preventing any disease. Before using any products referenced on the podcast, consult with your healthcare provider carefully, read all labels and heed all directions and cautions that accompany the products. Information found or received through the podcast should not be used in place of a consultation or advice from a healthcare provider. If you suspect you have a medical problem or should you have any healthcare questions, please promptly call or see your healthcare provider. This podcast, including Dave Asprey and the producers, disclaim responsibility for any possible adverse effects from the use of information contained herein. Opinions of guests are their own and this podcast does not endorse or accept responsibility for statements made by guests. This podcast does not make any representations or warranties about guest qualifications or credibility. This podcast may contain paid endorsements and advertisements for products or services. Individuals on this podcast may have a direct or indirect financial interest in products or services referred to herein. This podcast is owned by Bulletproof Media.
Episode 1439: “I Injected Stem Cells Into My Penis (Here's What Happened)”
Date: March 27, 2026
Guest: Dr. Mauricio Urzola, Co-Founder of RMI Clinic (Costa Rica)
In this candid and cutting-edge episode, Dave Asprey sits down with Dr. Mauricio Urzola at the RMI Clinic in Costa Rica to explore advanced stem cell therapies for cognitive enhancement, sexual health, joint repair, and aesthetic rejuvenation. The conversation moves from the science behind these revolutionary protocols to Dave’s personal experiences as a patient—most notably, the headline-grabbing procedure of stem cell injections into the penis, as well as treatments for the brain, face, and joints. The discussion is equal parts scientific deep-dive and personal testimonial, focused on how biohacking can lead to tangible upgrades in longevity, performance, and quality of life.
On Cognitive Protocol & Outcomes
“You can see inside your brain with fine detail exactly where you’re going and what the shape of the field will be. It’s like something from the future.”
— Dave Asprey [08:21]
On the Anecdotal vs. Statistical Evidence
“It’s always anecdotal until it’s your mom that you treated and she improved. At least, something very important is, the patients we’ve treated so far, 100% of them have shown important clinical improvements.”
— Dr. Urzola [09:49]
On ED Protocols
“Around 52% of these patients, refractory to medication, started to get functional erections.”
— Dr. Urzola [00:27 & 25:16]
On Personal Outcomes
“I noticed a very substantial difference in length, especially for doing multiple treatments that way. It was kind of ridiculous.”
— Dave Asprey [27:26]
Humor on Metrics
“On a ruler, how it says in and cm? IN stands for incorrect measure, and CM stands for correct measure.”
— Dave Asprey [27:26]
On Plasmapheresis
“When you get rid of all this inflammation in your body, you just function better...inflammation is not something nice to have around.”
— Dr. Urzola [18:36]
On Biohacking Access
“If you wait five years or ten years, these will be much more widely available because we’re showing that you can do it...some of this stuff is just really cool science fiction. That’s what we’re doing here.”
— Dave Asprey [33:03]
This episode pulls back the curtain on the future of advanced regenerative medicine and biohacking, blending clinical rigor with personal experimentation. Dave Asprey and Dr. Urzola showcase how targeted stem cell therapies—once science fiction—are now showing real promise for cognitive enhancement, physical health, sexual function, and longevity. The message is clear: while these treatments are cutting-edge and currently expensive, they pave the way for broader, more affordable access as the science matures and protocols are refined.
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