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Stephen Colbert
Hey, everybody. Stephen Colbert here about to read the copy for our sponsor. This is from our friends at Wonderful Pistachios. And I was the wonderful pistachio spokesman for years. Yeah, I have a real close association with nut meat. Okay. You know what they say when they reach for a snack? Don't hold back. And that's exactly the approach with Wonderful Pistachios. The don't hold back snack. These little wonders are so tasty, it feels like getting away with something. But surprise. Each serving has 6 grams of protein and 0 grams of regret. That's right. No guilt. Just glory, glory in our nuts. Whether it's a satisfying crack of in shell pistachios, and that's capitalized in shell, or the smooth, instant gratification of no shells. No judgment. That's just it. Just eat. No judgment. I take issue with one thing. It's instant gratification. It's super tasty smooth.
Drew Barrymore
It's a hard nut smooth.
Stephen Colbert
Exactly. I mean, even out of the shell, it's still a nut.
Drew Barrymore
We can't disparage the nuts. You.
Stephen Colbert
I'm not disparaging the nut. I'm describing the nut.
Drew Barrymore
Don't disparage any flavors.
Stephen Colbert
I'm not. I am celebrating the pistachio right now. I'm on board. I love pistachios. I love. I love crushed pistachio. Like a pistachio crusted trout. Oh, unbelievable. Instead of a trout amandine, a trout pistachio. Fantastic. Enough butter? Who cares? Very good. And I love pistachio ice cream.
Drew Barrymore
Have you had the sea salt and vinegar? Wonderful pistachio. It's delicious. I get em.
Stephen Colbert
I didn't even know I get them.
Drew Barrymore
Before the softball games.
Stephen Colbert
But that's. You see, it's been a while since I've been the spokesman for wonderful pistachios. I didn't realize we'd achieved new pistachio technology. Yeah. Yeah. Wow. Wonderful pistachios has every snack style covered. Right now. There's an obsession with jalapeno lime. There is an obsession session. It's almost a disorder. It's spicy, it's zesty. It's basically a flavor roller coaster in a nut. Snacking on the go. Grab a bag of no shells. Feeling contemplative and want to work for it a little. So earning it, they're saying if you want to earn your nut, crack open those in shell beauties. Either way, it's snacking like a champ. So the next time hunger strikes, don't hold back. Unless it's a hunger strike. And Then it's important that you do. Because whatever you're doing that for, I'm sure it's a worthwhile cause. Snack like you mean it with wonderful pistachios. Visit wonderfulpistachios.com to learn more.
Drew Barrymore
That was a wonderful.
Stephen Colbert
I wonder what more there is to learn. We just told them so much. We just told them so much about pistachios. But evidently there's a whole other world. There's an unexplored vista. They got a bunch of flavors.
Drew Barrymore
They got dill pickle, jalapeno lime, as we learned, smoky barbecue. There's a lot of different flavors.
Stephen Colbert
Wow. And I would not disparage any of them. No, no, no. Bring it on.
Drew Barrymore
Nothing bad to say.
Stephen Colbert
Nut me, nut. Nut me with nut meat.
Drew Barrymore
We're nut.
Stephen Colbert
No, we got nothing but nut. Nutty, nutty, nutty, nutty. Talk about, talk about, talk about, talk about, talk about nutty. Good.
Drew Barrymore
Buying a car in Carvana was so easy, I was able to finance it through them.
Stephen Colbert
I just.
Drew Barrymore
Whoa, wait, you mean finance? Yeah, finance. Got pre qualified for a Carvana auto loan, entered my terms and shot from thousands of great car options, all within my budget. That's cool. But financing through Carvana was so easy. Financed. Done. And I get to pick up my car from their Carvana vending machine tomorrow. Financed.
Stephen Colbert
Right? That's what they said.
Drew Barrymore
You can spend time trying to pronounce financing, or you can actually finance and buy your car. Today on Carvana financing, subject to credit approval. Additional terms and conditions may apply.
Stephen Colbert
Welcome, welcome one and all to the Late show. I'm your host, Stephen Colbert, ladies and gentlemen. Kevin. How's everybody feeling? Feeling good. All right, well, that may not last, thanks to our secretary of Health and Human Services, RFK Jr. I gotta say, Health and Human Services. A bit of an odd title for him because he looks neither healthy nor human. That reminds me, before you put your barbecue away this winter, you really gotta clean the grill. Speaking of which, fall is coming. That means cold weather. And a lot of people are thinking about vaccines. Well, think again, lot of people. Because thanks to new vaccine rules from Bobby Jr. CVS and Walgreens are clamping down on offering Covid vaccines in more than a dozen states.
Drew Barrymore
What?
Stephen Colbert
But that's why we go to drugstores to get medicine. Vaccines. Family sized bags of mini Snickers, school supplies, Christmas ornaments, personal massagers, a pallet of Yoo Hoo and tuna in a pouch. You know, drugstore. Get that hustuffed. That's enough for a pretty good Weekend. Because of the growing chaos throughout our public health agencies today, RFK Jr. Was hauled before the Senate. Now, Bobby seemed to be experiencing more upper respiratory distress than usual today. Listen to Mr. Health breathing into the microphone off camera while one of the senators speaks. So I appreciate you commenting on that in the last few. In the last minute and ten seconds that I have with you. I've never heard someone have sleep apnea while they're still awake. That. That is a lot of labored breathing into a microphone. Do we have a footage from RFK Jr. S opening statement? I knew Harvey Weinstein. I knew Roger ailes. I knew O.J. simpson came to my house. Bill Cosby came to my house. He looks good. He actually looks pretty good. The former head of the cdc, the one who just got fired, wrote a scathing op ed today saying that she was forced out for not rubber stamping RFK's anti vaccine policies. But old brainworm McGillicuddy remembered it a little differently. And Medicaid will help. She was the head of the cdc.
Drew Barrymore
That if she refused to sign off on your changes to the childhood vaccine.
Stephen Colbert
Schedule that she had to resign. No, I told her that she had to resign because I asked her, are you a trustworthy person? And she said no. Okay, then why did you believe her? Come on. Come on. She just told you she's untrustworthy. It took me a long time. It's taken me three years. It wasn't just Democrats going over Bobby, going after Bobby today. This is Wyoming Republican senator and physician John Barrasso, who this year voted to confirm Kennedy. I support vaccines. I'm a doctor. Vaccines work. Then why'd you vote for the anti vax guy? Look, look, I. I'm no doctor, but your results are in and you just tested positive for bull. Earlier this year, Kennedy fired 17 members of the vaccine advisory panel. And yesterday he said he plans to add seven new members to that panel. Of the seven new members, five of them are physicians. And as for the rest, these are my two ravens. They understand. Get that beak in. As you can imagine, RFK's picks are the creme de la cucu, including Katherine Stein, an epidemiology professor who called for an end to vaccine mandates at universities. Also, Dr. Kirk Milhone, a cardiologist who incorrectly claimed that vaccines contributed to rising infant mortality. And Dr. John Gaetanis, a pediatric neurologist who served as an expert witness for families who believed they were harmed by vaccines. Why do all those descriptions start out promising and end up crazy? We'll also be adding Dr. Bethany Smith, a pulmonologist who believes that asthma can be cured by human sacrifice. And Dr. Jeff Johnson, a kidney specialist who is in a common law marriage with a marmoset. It's not just about vaccines. RFK Jr says a lot of weird things. Last week at an event in Texas, he said this about children. I know what a healthy child is supposed to look like. I'm looking at kids as I walk through the airports today, as I walk down the street and I see these kids that are just overburdened with mitochondrial challenges with inflammation. That might be the creepiest way I've ever heard someone get their point across. Hello. Before you judge anything, I have to say, keep in mind I go to the airport and stare at your children and their troubled mitochondria. The vaccine chaos has not stopped with the feds. Yesterday, Florida Surgeon General Joseph Ladapo made this announcement. The Florida Department of Health, in partnership with the governor, is going to be working to end all vaccine mandates in Florida law. All of them. All of them. What an insane thing to cheer for. Come on. Who's in that room? Jim? Play that again with a shot of the audience. The Florida Department of Health, in partnership with the governor, is going to be working to end all vaccine mandates in Florida law. All of them. All of them. Ladapo. Yeah. Seem good. They seem healthy. Ladapo made this insane statement about vaccine mandates. Who am I as a government or anyone else? Or who am I as a man standing here now to tell you what you should put in your body? You're a doctor, that's who you are. Look at your name tag. You're supposed to tell us what goes in our bodies. Your job, sir. Your job. Your job is to tell me to cut down on salt, and my job is to pretend that I did that. The biggest immediate effect of all of this right now, Florida mandates that students have to be vaxxed against polio, diphtheria, measles, rubella, pertussis, mumps, and tetanus, also known as diseases that should only come up in Oregon Trail, although they have now updated that video game. So the most common message is you have died of Florida. It is. I got something. I got something. There you go. Now, it's hard. It is hard to overstate how bad this is for everyone who is in Florida or knows anyone in Florida or enjoys living in a world where you don't have to have 14 children because half of them get taken by viruses with names like the King's Evil or the Galloping Run. This is taking our country so far backwards. Because keep in mind, US school vaccination laws have been around since the 1850s when they were put in place to prevent smallpox. And they worked. You know how I know? Because I didn't die of smallpox yet. And it's not just kids. It's not just kids. This will also impact America's most vulnerable population, Disney adults. This is true. This is true. Infectious disease experts are sounding the alarm about Disney vacations. Yeah, everyone knows you can't get sick at Disney. They only got one doc and he's got his hands full with Sneezy and a drug addict named Dopey. Speaking of diseases, speaking of diseases. Americans caught from Florida. Donald Trump. The President Trump is concerned with something he finds far more dangerous than disease. Big ugly windmills, they ruin your neighborhood. The windmills. The windmills that don't work when you need them. The windmills are driving the whales crazy. Obviously. You want to see a bird cemetery, just go under a windmill. You want to see a bird cemetery. You want to see a bird widow in her veil crying over the casket. An open casket. I don't know why they made that choice. It looks like a mess in there. She's squawking. It should have been me. All while throwing up in her little babies mouths because they're hungry. And papa bird isn't there anymore. He was murdered. It was bird murder. It was birder. Rest in beak, everybody. Thanks to the wind. Rest in Trump has. Trump has hated windmills. Trump has hated windmills ever since 2011 when he unsuccessfully tried to stop an offshore wind farm from being built near one of his Scottish golf courses. Now he's taking his revenge. This week the White House ordered its agencies to escalate the fight against offshore wind. Yes, the fight against wind has begun. Mimes of America assemble. Did mimes do that? I don't know what that means. Trump is putting together a crack squad to find reasons to attack wind power. Robert F. Kennedy Jr. Howard Lutnick and Pete Hegseth are part of a departmental coalition team to investigate the risks from offshore wind farms. Investigate them well, boys. Get right up close under those spinning turbines. Just really lean in, okay? Get in there. Maybe you'll see a bird cemetery. We got a great show for you tonight coming up.
Drew Barrymore
Drew Barrymore want to transform your skin and challenge everything you thought you knew about Clean beauty. Primally pure is going back to the roots of skincare. Literally. Their tallow based products are grounded in ancestral wisdom and made with grass fed beef fat. Yes, beef fat.
Stephen Colbert
Because sometimes nature knows best.
Drew Barrymore
Tallow isn't a trend. It's skin identical, meaning it closely mimics the oils your skin naturally produces. That makes it deeply nourishing, incredibly bioavailable, and wildly effective, especially for sensitive, dry or reactive skin that's tried everything else. Thousands have made the switch and never looked back. So if you're searching for something that actually works, look no further. Head to primallypure.com to shop their cult favorite, tallow deodorant, and explore the full line. That's P R I M A L L Y p u r e.com your skin will.
Stephen Colbert
Thank you. Labor Day savings are here at the Home Depot with up to 35% off, plus up to an extra $450 off select appliances like LG. Keep your routines running smoothly with an LG refrigerator you can count on from the Home Depot. And with the connected ThinQ app, you'll know if the door is left open and when to replace the filter. Gear up for fall with Labor Day savings on lg, America's most reliable appliance brand at the Home depot offer, valid August 21 through September 10, US only. See store online for details. Welcome back, everybody. Ladies and gentlemen, my first guest tonight has been charming audiences for decades, first as an actor, and now as the host of the Drew Barrymore show on Saturday, cbs. Please welcome back to the Late Show, Drew Barrymore. Hi. Hi. Hi. No, please, please. You're the guest. Thank you.
Drew Barrymore
I was like, is Evie here?
Stephen Colbert
No. No. She says hi. She says hi.
Drew Barrymore
I love Stephen's wife so much.
Stephen Colbert
I know. I'm mildly jealous, you guys. Cause you guys do things without me.
Drew Barrymore
Yeah, I know. And the last time we were supposed to get together, my daughter ended up having, like, an accident. And I was, like, calling her, and she's fine. She's fine. Yes. Everything's fine. She's actually my daughter. Actually, she got in an e bike accident. In the city? No, in France, which sounds so fabulous. So, yes, we were in fabulous France. And then she had an E bike accident, and she was, like, a mile out in the mountains and ripped her whole elbow open. It was completely just. I mean, we've spent days in an er. In and out, she's fine. But she ripped off her bra and turned it into a tourniquet, and I was like.
Stephen Colbert
You raised her right. You raised her right. Did you ever prep her for that?
Drew Barrymore
No, it's just. That's who she is.
Stephen Colbert
Wow.
Drew Barrymore
And I just marvel at her.
Stephen Colbert
But you had to have done something right for her. To have that presence of mind.
Drew Barrymore
You think I have anything to do with it? Of course.
Stephen Colbert
They learn by example, don't they?
Drew Barrymore
God, I hope I'm that cool.
Stephen Colbert
Wow. Well, you're about to start season six. Yes. Of the Drew Barrymore show this coming Monday. Yes.
Drew Barrymore
Yes.
Stephen Colbert
But. But that means you're just coming off the summer hiatus.
Drew Barrymore
Yes.
Stephen Colbert
Not all of it was in the er. No. Now, I understand that you and I share something. Is that we. I love a long road trip.
Drew Barrymore
Yes.
Stephen Colbert
And you love road trips.
Drew Barrymore
Yes. Cause you are beholden to no one.
Stephen Colbert
No. You're free. You're the wind.
Drew Barrymore
Yeah. And I like doing this.
Stephen Colbert
You can leave when you want and.
Drew Barrymore
Stay if you like.
Stephen Colbert
Exactly.
Drew Barrymore
I mean, I've definitely screeched out of a few places.
Stephen Colbert
Yes.
Drew Barrymore
Get me out of here. And then some. You just, you know. And I like to flip coins at Intersect. Okay, so here's how I start. I rent a Tioga, which is a. It's a type of rv.
Stephen Colbert
Like a little Winnebago or something.
Drew Barrymore
Yeah. You could have a regular driver's license.
Stephen Colbert
Okay. Oh, I understand.
Drew Barrymore
And you start from one place, your.
Stephen Colbert
Own bathroom and everything.
Drew Barrymore
Yeah. But you cannot poo in there. Don't you dare ever poo in that bathroom. Cause you're gonna be in it for a while.
Stephen Colbert
Let me write that down.
Drew Barrymore
That will come back to haunt you.
Stephen Colbert
Don't poo in Drew's bathroom.
Drew Barrymore
That's right. That's right.
Stephen Colbert
Drew. Say, no poo.
Drew Barrymore
No poo here. That's when you pull over and you find a bathroom. But you can pee in there. And then you go and, you know, clean it and. But you. So you start somewhere and you end somewhere. So, like, one trip, I.
Stephen Colbert
Hold on, Let me write that down. You start, end. Got it. Yes. Yes.
Drew Barrymore
One time I started in Los Angeles, and we knew we had to be in New Hampshire in a month. And so we just took whatever route came, you know, to us.
Stephen Colbert
And where do you stay? You just pull up to, like, a Motel 6. What do you do?
Drew Barrymore
We stayed in RV parks. We stayed in.
Stephen Colbert
You're staying in the thing?
Drew Barrymore
Kind of a little bit of, you know.
Stephen Colbert
Are people surprised? The other people at the RV park?
Drew Barrymore
I had a bag of weed in a Motel 6, and I was so.
Stephen Colbert
Mad.
Drew Barrymore
I would hide my weed under the mattress. And I was in the next state, and I was like, all right, time to roll. Oh, no.
Stephen Colbert
Hey. Happy birthday. Oh, thank you. I know. You just turned the big five zero this past year.
Drew Barrymore
I did.
Stephen Colbert
Okay.
Drew Barrymore
And I did. I've never been Happier.
Stephen Colbert
I like this. I like this that you're celebrating that with 50 effets.
Drew Barrymore
Yes, that's right.
Stephen Colbert
What are we effing these days?
Drew Barrymore
Well, it was the actress Ellen Pompeo of Grey's Anatomy. The great Meredith Grey. Exactly. She came on the show a few years ago and she introduced me to this idea of the 50 effets. And at the time, I was like, 47. I don't know, somewhere around there, maybe 48 Pisces. Terrible with numbers. Anyway, I was like, what is this that she speaks of, this liberation? Because I've always been very concerned with, you know, probably more how people feel. First. Yeah, like the Maya Angelou quote, you know, it's not what people think of you, it's how you make them feel. But I think we all do care what people think, you know, and it can be a good way to have a check on yourself, but it can also be really just to our downfall. You know, we care so much and we're so worried about the Phantom. They. Or the thing you said that night, you know, I mean, where you left.
Stephen Colbert
Your weed.
Drew Barrymore
At the Motel 6 in New Orleans. That's where it was.
Stephen Colbert
So what are you saying? Effort to caring what people think of you.
Drew Barrymore
I don't think I'll ever be able to totally achieve that. But what I have achieved in and the efforts is to realize that it is no longer worth it for me to dislike me.
Stephen Colbert
Ooh, I like that.
Drew Barrymore
Really?
Stephen Colbert
Yeah, I like that a lot. That gets right to the heart of it. Which brings me to another announcement. I just found out that you made a surprising new best friend.
Drew Barrymore
Oh, yes, I did. Yes.
Stephen Colbert
And this person is a big celebrity.
Drew Barrymore
Oh, yeah, they are.
Stephen Colbert
They all know this person, apparently. And you love them. Tell the audience who your new best friend is.
Drew Barrymore
Well, now that I said, they're a big celebr.
Stephen Colbert
It's me.
Drew Barrymore
It's me. I'm my best friend.
Stephen Colbert
Yes. Drew Barrymore Penn's essay, choosing Love to Love a single life in 50. I want to be my own best friend. What does your best friend do for you?
Drew Barrymore
Well, she's nice to me, and I think we all, you know, she's there for you. She's there for me. I don't know. Does anyone else, like, take themselves down and even call themselves names or say, oh, my God, how could you screw that up? Like, you loser, you're a failure at this. Or, God, you should have done that better. Or, how dare you do that? What's wrong with you? These things that you would not speak to other people, you would not speak to a child. But somehow you are fair game. And I'm so sick of it that nothing is worth me talking this way to myself anymore. I'm done.
Stephen Colbert
That's it. You did it. That's fantastic.
Drew Barrymore
And so if this is what the 50 effets are, then I've waited my whole life to get here because my expectations and my standards for myself are impossible to live up to.
Stephen Colbert
Sure. So you're not lowering your expectations for yourself. You're just not killing yourself emotionally if you don't reach them.
Drew Barrymore
That's right. Because I think a lot of us feel like we have to push ourselves in order to achieve things. You know, when did like sitting back and just hoping for the best work out so well for any of us? Not a lot sometimes. But we are self generators. We are our motivation, our inspiration and the, you know, we're accountable for how we live our lives and what we accomplish in it. And accomplishment to me, or any definition of success has only to do with if you are at ease in your own body. Like you. The reason I'm my best friend is because I'm what I have in this world now. I think my friends are my first family and I love my children more than anything I've ever known in my life. But I have not been in the mix. It's like I was on the sidelines and it was, you know, I've been a big people pleaser and I think a lot of us are. And I think people pleasing almost gives us an excuse, like it's the other person's fault. Oh God, we're just such people pleasers. This starts and ends with me and this isn't about other people. I have to take responsibility for myself in a solo way. And then I just. This is all new to me. So I'm like a wobbly calf that just got born. But I'm learning to walk, walk. And it feels really good.
Stephen Colbert
You look perfectly sturdy. We have to take a quick break. We'll be right back with more Drew Barrymore, everybody.
Drew Barrymore
Abercrombie kids is bringing the ultimate first day energy back to school. It all starts with on trend outfits for that front door photo shoot. Plus the coolest tees, shorts and jeans to take them through the rest of the year. Get them ready for their close up and keep them comfy too. Make this grade their best one yet. Shop all things back to school in store, online and in the app.
Stephen Colbert
Does it ever feel like you're a marketing professional just speaking into the void? But with LinkedIn ads, you can know you're reaching the right decision makers. A network of 130 million of them. In fact, you can even target buyers by job title, industry, company seniority, skills and. Did I say job title? See how you can avoid the void and reach the right buyers with LinkedIn ads. Spend $250 on your first campaign and get a free $250 credit for the next one. Get started@LinkedIn.com Campaign terms and conditions apply. You know you love her. Drew Barrymore is here. Season 6 of the Drew Barrymore show starts Monday.
Drew Barrymore
That's right, it does.
Stephen Colbert
Okay.
Drew Barrymore
And we have some fun people coming this week.
Stephen Colbert
Who do you have coming?
Drew Barrymore
Well, we have Jennifer Aniston, Issa Rae, Katherine Zeta Jones. Catherine Zeta Jones.
Stephen Colbert
And Zeta Jones. Both of them?
Drew Barrymore
Yeah, both of them. And her husband, Michael Douglas.
Stephen Colbert
Wow. And Michael Douglas.
Drew Barrymore
And Michael Douglas, just to name a few. And then also, funny enough to say in this room, David Letterman.
Stephen Colbert
And his beard.
Drew Barrymore
Yeah, I mean, I've spent some times here with David Letterman in this room.
Stephen Colbert
You have? I'm only mildly insulted that you've never gotten on the desk. All right, so now hold on.
Drew Barrymore
All right, so you want me to do a little dance for you?
Stephen Colbert
I promise you I don't. That was just a joke. I promise you. I don't know. But we're all about. No, no, no, no, no. Next time. Next time. Later, Sam. Well, Drew, I'm afraid that's all we have time for, everybody. Uh huh. And tell me, tell me where the pain is. Drew. Drew Barrymore, everybody. You're the best. You are the best. Thank you for listening to the Late Show Pod show with Stephen Colbert. Just one more thing. If you want to see more of me, come to The Late Show YouTube channel for more clips and exclusives. Now streaming on Paramount. Someone is trying to frame us. Until our names are cleared, we're fugitives from Interpol Like Bonnie and Clyde. We better see snacks. NCIS Tony and Ziva now streaming on Paramount plus. Now streaming on Paramount plus. Someone is trying to frame us. Until our names are cleared, we're fugitives from interval Like Bonnie and Clyde with better snacks. Espionage. You still as good a shot as you used to be? Better. Is there love language? We like to walk that fine line between techno thriller, romantic comedy we make up our own rules. NCIS Tony and Ziva now streaming on Paramount plus.
Date: September 5, 2025
Host: Stephen Colbert
Guest: Drew Barrymore
In this lively and heartfelt episode, Stephen Colbert sits down with actress, talk show host, and author Drew Barrymore. The pair delve into everything from current controversies in public health to Drew’s personal journey toward self-love in her 50s. The conversation is marked by trademark Colbert wit and Barrymore’s infectious warmth, covering topics ranging from road trip adventures to wisdom about aging, self-acceptance, and thriving as your own best friend.
Notable Quotes:
Notable Quotes:
Memorable Moments:
Notable Quotes:
Memorable Exchange:
The episode is a delightful blend of sharp political satire and heartfelt personal reflection. Colbert’s incisive humor sets the stage for an introspective, empowering conversation with Drew Barrymore. Listeners are treated to candid stories of family, aging, and self-growth, alongside the playful banter for which both Colbert and Barrymore are known. The lasting message: self-compassion and authenticity become even more valuable as you grow older.