Podcast
The Longevity & Lifestyle Podcast
Hosted by Claudia von Boeselager · EN
Claudia von Boeselager is here to empower you to live at your best and reach your highest potential by sharing groundbreaking strategies, tools, and practices for your longevity and lifestyle from the world’s pioneering experts. For more, visit: LLinsider.com Welcome to The Longevity & Lifestyle Podcast! Claudia is on a mission to help 1 billion people optimize their lives and reach their fullest potential so that they can make a positive impact in the world! Tune in to learn how to increase your healthspan, improve the quality of your life and lifestyle also around entrepreneurship, managing personal finances and investing, and much more. Topics include how to optimize your health in areas such as sleep, nutrition, cognition, metabolic health, reversing diabetes, intermittent fasting, biomarkers, gut health, hormones, the female biorhythm, skin, hair, biohacking tips, supplements, mastering your mindset, improve your relationships and overall happiness, meditation, how to perform better in business, optimize your daily routines, achieve peak performance, biohacking your age, and more. Claudia is a Peak Performance Coach and Serial Entrepreneur passionate about helping you thrive in all areas of your life & business! She knows what it’s like to feel close to burnout and not be at your best. Thanks to 10+ years of research, countless interviews with global pioneers, and hundreds of thousands spent, she continues to uncover how you, too, can achieve peak performance to live your life at its best - all while having lots of fun! So make sure to TUNE IN and start living the best version of yourself!
27episodes
Episodes
Newest firstAll episodes
#249 Dr. Momchilo Vuyisich — How Your Microbiome Controls Immunity, Chronic Disease & Longevity
6d ago00:52:12Tap to summarizeWhat if your microbiome is influencing far more than digestion - from your brain and immune system to aging, energy and chronic disease risk?In this fascinating episode, Dr. Momchil “Momo” Vuyisich joins Claudia to unpack the science of the microbiome, microbial function and personalized nutrition.We explore:• Why Your Gut Microbiome Shapes Human Health • The Difference Between Microbes and Microbial Function • How Gut Bacteria Influence Brain Health and Cognition • Why Antibiotic Overuse May Increase Chronic Disease Risk • The Role of Fermented Foods and Probiotics • Why Personalized Nutrition Is the Future of Healthcare • The Importance of Keystone Species Like Akkermansia • How Food Preservatives and Modern Diets Affect the Gut • Why Testing and Data Create Actionable Health Insights • The Future of Microbiome Science and Precision HealthThis conversation is a powerful reminder that longevity starts with understanding the invisible ecosystem living inside us.Timestamps 00:00 - Why chronic stress may be destroying your body 00:38 - Dr. Momchilo Vuyisich’s background and work at Viome 01:33 - Why humans are an ecosystem, not just an individual 03:58 - Why fiber is essential for feeding the microbiome 04:52 - How the microbiome is shaped at birth 06:31 - Why asthma, food allergies, and IBD may be rising 08:13 - How mothers can support a healthier microbiome before pregnancy 09:40 - The hidden long-term cost of antibiotics 11:06 - How preservatives and non-organic meat may harm the microbiome 12:22 - How to rewild your microbiome after disruption 16:46 - Why some keystone strains are so hard to restore 18:19 - Microbial function vs. microbial strains 20:49 - How microbial metabolites affect the brain and body 24:25 - Why personalized nutrition may matter more than generic healthy eating 27:20 - The four pillars of health: food, exercise, Zen, and sleep 29:58 - Why there is no single optimal diet for everyone 32:34 - Minimum effective exercise for longevity 34:21 - Why stress management is non-negotiable 37:48 - Why sleep sets up your entire next day 39:33 - Are naps helpful or harmful? 40:22 - The microbiome and neurodivergence 43:07 - Can chronic disease become preventable? 44:31 - Preventive maintenance for the human body 46:34 - How the microbiome may influence immune memory 48:13 - What Dr. Vuyisich is building at Viome now 51:15 - Where to follow Dr. Vuyisich and learn moreSubscribe to Longevity & Lifestyle for science-backed insights on longevity, health optimization, brain health, metabolic health, women’s health, and performance.#microbiome #guthealth #longevity #healthoptimization #immunity #brainhealth #metabolichealth #personalizednutrition #biohacking #healthyaging
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#248 Maila Reeves - The Truth About NAD+, Peptides, and Longevity - What Actually Works
2w ago00:43:48Tap to summarizeWhat if your body starts warning you long before real symptoms appear? In this episode, Claudia sits down with Mila Reeves to unpack what real health ownership looks like - from reading your body’s early signals to understanding NAD+, peptides, supplement quality, diagnostics, hormones, energy, and the dangerous gap between good science and good marketing.Maila shares her personal path into longevity, why she believes prevention is no longer optional, how NAD+ moved from addiction clinics into the mainstream longevity world, what most people misunderstand about delivery methods, why quality control in supplements matters far more than most consumers realize, and how to think more clearly about peptides, personalization, and aging well.This is a practical conversation on how to stay sharp, energized, and resilient for longer - without falling for hype.Timestamps00:00 - Your body gives signals before breakdown01:33 - Intro to Maila Reeves03:07 - Maila’s origin story: fashion, law, strategy, and longevity06:35 - The problem with snake oil in longevity08:36 - What to check before buying supplements09:13 - When longevity became personal12:59 - Visualizing the future: how do you want to age?13:59 - Why people still outsource their health16:42 - The knowledge gap in medicine and women’s health19:01 - Why your doctor is not always right for your body21:27 - Mila’s non-negotiables: positivity, gratitude, NAD, NAC, vitamin D22:51 - What NAD+ actually is24:27 - Why NAD+ was first used in addiction recovery26:20 - IV vs subcutaneous vs capsules28:05 - Why delivery method matters for NAD+30:02 - What’s the most effective way to take NAD+?31:55 - Claudia’s experience using NAD+ for travel and energy33:29 - Hair, libido, brain clarity, skin, sleep, and hormones35:12 - Who should not take NAD+36:12 - Why quality and certification matter38:06 - Peptides explained simply40:49 - Why peptides are becoming so popular41:25 - The fundamentals still matter most42:40 - Final message: prevention is not optionalReady to upgrade your health, energy, and longevity? Download my free 10 Life & Longevity Hacks Playbook and start living smarter, stronger, and longer → https://longevity-and-lifestyle.com/freebie#longevity #NAD #peptides #biohacking #healthoptimization #womenshealth #supplements #antiaging #podcast #ClaudiaVonBoeselager
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#247 Claudia von Boeselager – Your Environment Is Aging You (Or Healing You): Inside LUMARA Longevity Living & Wellness Real Estate
3w ago00:12:34Tap to summarizeWhat if your home is quietly accelerating your aging… or actively supporting your longevity?In this solo episode, Claudia explores one of the most overlooked pillars of health: your environment.We spend over 90% of our lives indoors - yet most people focus only on nutrition, exercise, and supplements while ignoring the space their body lives in.Claudia breaks down:The five key environmental factors shaping your biologyWhy air, water, light, materials and nervous system load matterHow your environment impacts energy, sleep, inflammation and performanceThe role of mitochondria and energy allocation in healthWhy you can’t optimize your biology in a survival stateThe truth about “healthy” swaps like saltwater poolsWhy wellness real estate is becoming the future of luxury and investmentThis episode is an invitation to shift from optimizing your body… to optimizing the environment that supports it.Watch the full episode here
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#246 Claudia von Boeselager on Women Who Lead And Sell Podcast | Reverse Your Biology, Reclaim Your Power: From Burnout to Biohacking & Purpose
4w ago01:05:55Tap to summarizeClaudia von Boeselager is a former Goldman Sachs banker turned biohacker, longevity entrepreneur, peak performance coach, and investor who reversed her biological age by 18 years.In this conversation, she shares the burnout moment that changed everything, what biohacking really means beyond supplements and gadgets, how purpose and alignment affect health and performance, and why women can use their biology as an advantage in leadership, business, and life.[00:00] Introduction to Claudia’s journey[03:00] Purpose, alignment, and “following your bliss”[07:00] What biohacking really means[15:00] The burnout moment that changed everything[20:00] Women, leadership, and playing small[30:00] Female biology as a business advantage[40:00] Sales, money mindset, and impact[50:00] Building businesses with purpose[58:00] Rapid-fire insights and lessonsClaudia von Boeselager is the founder of Longevity & Lifestyle, a platform focused on helping ambitious people optimize health, performance, and lifespan through science-backed tools, expert insights, and practical strategies. Her work sits at the intersection of longevity, women’s health, biohacking, and high performance.Newsletter: https://longevity-and-lifestyle.com/llinsiderWebsite: https://longevity-and-lifestyle.com/Follow on Instagram: https://www.instagram.com/longevityandlifestyle/Follow Claudia on LinkedIn: https://www.linkedin.com/in/claudia-von-boeselagerSubscribe on YouTube: https://www.youtube.com/channel/UCZF-s8jsUejc0TpVqnFE1lQ
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#245 Matt Abrahams — Why You Freeze Under Pressure: How to Think Faster, Speak Smarter & Communicate with Confidence
4w ago00:45:40Tap to summarizeEver blanked in a meeting or "frozen" during a big presentation? You aren't alone.Communication expert Matt Abrahams joins Claudia von Boeselager to explain the science of why high performers blank out and how to rewire your brain to stay calm and clear.Download my FREE 10 Life & Longevity Hacks Playbook to start living smarter and stronger: https://longevity-and-lifestyle.com/freebieIn this episode, we dive into:00:00 – Why smart people "freeze" when the stakes are high05:30 – The biology of anxiety and cognitive overload12:00 – Why connection matters more than perfection18:45 – The "Pace, Space, Grace" framework for better listening25:10 – How to use structure instead of memorization32:00 – Practical tools for high-stakes interviews & meetings40:00 – The key to becoming a master communicatorAdditional Resources: ✨ Join the LLInsider for peak performance strategies: https://longevity-and-lifestyle.com/llinsider ✨ Full show notes & links: http://longevity-and-lifestyle.com/podcast-245-matt-abrahams#LongevityAndLifestyle #CommunicationSkills #MattAbrahams #PublicSpeaking #MindsetShift #PeakPerformance #LeadershipDevelopment
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#244 I Lost My Voice for 3 Days - Here’s What It Taught Me | Claudia von Boeselager
Mar 2500:10:27Tap to summarizeIn this personal solo episode, Claudia shares a powerful and unexpected experience - losing her voice completely for three days.What initially felt frustrating became a profound reminder of how the body communicates when we’re moving too fast.In this reflective conversation, Claudia explores the deeper meaning behind forced silence and what it taught her about listening, slowing down, and reconnecting with our inner signals.In this episode we explore:• What losing her voice revealed about stress and overextension• Why the body often speaks before burnout appears• The hidden intelligence of the body and how it communicates with us• The power of silence and stillness in a hyper-stimulated world• How to start listening more carefully to your body’s signalsThis episode is an invitation to slow down, reflect, and reconnect with the wisdom already within you.
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#243 Dr. Meenal Agarwal - The Eye-Brain Connection, Screen-Induced Vision Loss & Spatial Awareness: How Modern Life Is Rewiring Your Brain
Mar 1800:47:16Tap to summarizeWhat if your vision was telling you far more about your health than you realized?In this fascinating episode, Dr. Meenal Agarwal, board-certified optometrist, spatial awareness expert, and authority on the eye–brain connection, reveals how vision is not just about eyesight - it’s a direct reflection of brain function, nervous system state, and emotional health.Blending clinical science, neuroscience, mindfulness, and compassion, Dr. Agarwal explains how stress, trauma, and chronic overload subtly alter how we see the world - and how retraining vision can support healing, resilience, and longevity. From spatial awareness to visual processing, this conversation reframes vision as an active brain skill and a powerful portal into whole-body wellbeing.We explore:The eye–brain connection and nervous system regulationHow stress and trauma show up in visionSpatial awareness and its role in balance, safety & longevityWhy vision is a brain function, not just an eye issueHow mindful vision practices can support healing and clarityThis episode invites you to see differently - both literally and metaphorically.
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#242 Olga Kaplan — Sacred Sexuality, BDSM, Trauma Healing & Intimacy: Reclaiming Pleasure, Power & Emotional Safety
Mar 1201:04:17Tap to summarizeWhat if desire isn’t indulgence - but your life force?In this deeply embodied conversation, intimacy and sacred sexuality coach Olga Kaplan returns to explore how trauma lives in the body, why intimacy is about presence, and how conscious kink and BDSM can be used therapeutically for healing.We explore:• What intimacy truly means (deep presence with yourself and another)• Tantra as weaving life experiences into embodied aliveness• The difference between kink, BDSM and trauma-informed practice• Why trauma is not the event — but what happened without consent• How impact play, consent and role dynamics can help rewire the nervous system• Why libido is a powerful biomarker of health and vitality• The “sex recession” and why younger generations are disconnecting• Practical tools: breath, sound, movement & energetic hygiene• How long-term couples can revive polarity, play and desireThis episode is about reclaiming your body, your pleasure, your vitality — and remembering that your desire is not shameful, it’s sacred.
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#241 Dr. Chris Davis & LUMARA Collective - The Real Cause of Heart Aging: Oxidative Stress, Nitric Oxide & Vascular Health
Mar 401:09:47Tap to summarizeWhat if “heart health” isn’t about managing numbers… but fixing what’s driving vascular aging in the first place?In this episode, triple board-certified cardiologist Dr. Chris Davis joins Claudia (with Lumara co-founders Ashley Madsen and Alexandra Cochrane) to unpack a modern, prevention-first approach to cardiovascular longevity.We explore:Why conventional cardiology often becomes a “revolving door” of repeat events and proceduresThe “getting rusty inside” explanation of oxidative + nitrosative stress (and what it does to your arteries)How nitric oxide signaling influences vascular function, performance, and agingWhy Lp(a) is trending, what matters now, and how to think about outcomes vs numbersWhy coronary imaging (calcium and plaque assessment) can remove the guessworkHow toxins, membranes, and mitochondria connect to cardiometabolic declineThe emerging frontier: membrane medicine + mitochondrial support (including peptide discussion)Practical levers you can start with: Zone 2, environment upgrades, and reducing daily toxin loadThis is a high-signal conversation for anyone who wants to measure what matters, reduce risk upstream, and build a stronger, longer healthspan.
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#240 Dr. Louise Hecker — Can Psilocybin Slow Aging? The First Study on Telomeres, Cellular Longevity & Systemic Anti-Aging
Feb 2500:46:14Tap to summarizeWhat if psilocybin wasn’t just a mental health breakthrough — but a longevity intervention?In this powerful, science-driven conversation, Dr. Louise Hecker shares groundbreaking research exploring how psilocybin’s active metabolite, psilocin, may influence the fundamental biology of aging.We explore:• How psilocybin impacts cellular senescence, one of the key drivers of aging• The surprising effects on oxidative stress and antioxidant pathways• What happened to telomere length in aging cell models• Why serotonin (5-HT) receptors exist throughout the body — not just the brain• The dramatic survival results in aged mice given monthly high-dose psilocybin• Why psychedelic research was stalled for decades — and what’s changing now• The potential role of psilocybin as a future geroprotective agentThis episode moves beyond hype and into mechanism — exploring how psychedelics may influence healthspan at the cellular and systemic level.A fascinating look at how a once-misunderstood compound could reshape preventative medicine and aging science.
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