In this episode of The Macro Hour, Nikkiey breaks down the truth about GLP-1 medications and their impact on body composition—especially the often-overlooked risk of muscle loss.

While these medications can be effective for weight loss, Nikkiey explains why the number on the scale doesn’t tell the full story. Losing muscle can slow your metabolism, impact long-term results, and make weight regain more likely—especially for women in midlife.

She also shares the non-negotiables for protecting your body while using or coming off GLP-1s, including prioritizing protein, strength training, tracking body composition, and building a sustainable plan.

If you’re considering GLP-1s or currently using them, this episode will help you approach them in a way that supports your long-term health, metabolism, and results.

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Welcome to The Macro Hour Podcast, where we talk about mindset, methodology, and tactics that will help you lose body fat, build muscle, be strong, and feel insanely confident. We've got a no-bullshit, no-nonsense approach with a lot of love ...

The Truth About GLP-1 Weight Loss and Muscle Loss | Ep. 358