
Hosted by Keyvan Koushan, MD, FRCSC · EN

This episode is a reproduction of the second retina-focused EyeNovation webinar series and a result of a special collaboration between Canadian Retina Society and Canadian Ophthalmological Society. Dr. Angie Fong from the University of Hong Kong gives a fantastic overview of pachychoroid spectrum of conditions with a focus on central serous chorioretinopathy and polypoidal choroidal vasculopathy. She gives an in-depth review of pathogenesis, recent clinical trials, and emerging management strategies and discussed the incidence and risk factors for PDS progression based on natural observation studies. Dr. Wai-Ching Lam from the University of British Columbia is the moderator for this webinar.

Dr. Wu discusses prospective cognitive outcomes of children who had treatment for Retinopathy of Prematurity. The analysis suggests that cognitive outcomes were similar for children who had either laser or anti-VEGF injections for ROP treatment. Dr. Wu will be one of the invited guest speakers at the Canadian Retina Society meeting in Vancouver, BC from April 25-April 27, 2025. You can register for this meeting at: https://crsscr.ca/meeting Discussed article: Wu PL, Shih CP, Huang YS, Chen HC, Hsueh YJ, Lee CW, Chiang MC, Lien R, Lee CC, Chu SM, Chou HD, Liu L, Chen KJ, Hwang YS, Lai CC, Wu WC. ADMINISTERING INTRAVITREAL BEVACIZUMAB FOR RETINOPATHY OF PREMATURITY: 8-Year Cognitive Outcomes In A Prospective Cohort. Retina. 2024 Nov 1;44(11):1952-1960. doi: 10.1097/IAE.0000000000004222. PMID: 39121508.

This episode is a recording of the retina-focused EyeNovation webinar episode which was a collaboration between Canadian Ophthalmological Society and the Canadian Retina Society. Dr. Chakravarthy will provide a background to the double layer sign, its definition and how it is detected. Data to support the presentation will be from the EDNA trial . This study possesses an imaging dataset that was captured longitudinally in over 500 high risk eyes and obtained robust rates of progression to neovascularization as well as time to the event. The presence of the DLS and or other features of intermediate AMD were assessed at baseline and included measurements of length of separation of the RPE from its basement membrane, height of separation and the number of B scans involved. Rates of progression in eyes without and with DLS were computed and models built to assess risk of progression to neovascularization. In addition the DLS and SIRE signs were compared for their contributions to risk of progression. The findings from these analyses and their clinical significance will be discussed . Make sure to register for the Canadian Retina Society (CRS) annual meeting which will take place in Vancouver, BC from April 25-27, 2025. Go to https://www.crsscr.ca to register.

Dr. Charles Wykoff discusses results of DRCR protocol T ancillary study on plasma free VEGF concentrations after different intravitreal anti-VEGF injections for diabetic macular edema. Full reference of the discussed article: Jampol, L. M., A. R. Glassman, D. Liu, L. P. Aiello, N. M. Bressler, E. J. Duh, S. Quaggin, et al. "Plasma Vascular Endothelial Growth Factor Concentrations after Intravitreous Anti-Vascular Endothelial Growth Factor Therapy for Diabetic Macular Edema." Ophthalmology (Mar 7 2018).