
Loading summary
Dr. Amy
Welcome to the Thyroid Fixer podcast, where I'm all about helping you lose that stubborn weight that won't come off no matter what you do. Get off your couch at 2pm and get through your day with energy. And stop counting the hairs that come out of your head. I'm your host, Dr. Amy, and I'm here to help you get optimized with your thyroid and your hormones. It's all part of living. Our mantra, better thyroid, better hormones equals a better life. So let's get you back being the badass human that you're meant to be. Let's approach it from a thyroid and hormone optimization standpoint. Between myself and my guests, you will be loaded down with information to take control of your health and get back to being you. So let's get started. Do you ever feel like your energy is just off? Like you're not fully alive during the day and then you're restless at night? Chances are your circadian rhythm, your body's natural clock, has been disrupted by a lack of sunlight. So what's the solution? This is where I bring in the mito luxe sun lamp. It is designed to mimic the best of the sun, helping restore your body's rhythm. UVB for vitamin D, that helps our energy. Red and infrared light for mitochondrial support. And let's not forget our skin and collagen formation. It's amazing. It's like a reset button for your health that you just turn on and then sit in front of and enjoy. And during those long, gloomy winters, those long days, it's a lifesaver. No more winter blues, by the way, improves your mood. No more low energy, improves your energy. So you need to get yourself a mito luxe lamp. It's so portable, it's so easy. I sit it on my desk, I take it with me to my bathroom, I stick my face in front of it. After I wash my face, put on my serum. It is amazing for your skin, but amazing for your energy. Amazing for your mood. You want to go to mitolux.com forward/doctor Amy. So that's M I T O L U X.com forward slash dash R A M I E. You're going to use the code? Dr. Amy. They are giving me the code to give to you for 10% off. You will not regret it. This is the best, best, best red light, hands down. I have many of them in my house. This is the only one that I use. It is so easy, portable, and it works. The most important thing is it works. So mitrelux.com forward slash Dr. Amy. Don't forget to use the code. Dr. Amy. Since the release of Metabolism Fixer we have been bombarded by stories of of people just raving about it and the results that they're getting. So what we're seeing across the board, control of appetite and without the use of expensive GLPs. Because metabolism contains that patented trademark ingredient suppressor has a boatload of studies behind it reducing appetite by 69%. We have heard massive reports thanking us. Thank you for Metabolism Fixer because finally I have control over my appetite once and for all. I'm not binging, I'm not overeating and that's really half the battle. But beyond that, we have to get the metabolism up. We have to get your metabolism up. How do we do that? Metabolism Fixer contains T2. Now it also contains purple tea and green tea which both increase your metabolic furnace. But T2 is really the key. That forgotten thyroid hormone that increases your basal metabolic rate stimulates brown adipose tissue. That's why you're jumping into cold plunges people to stimulate that brown adipose tissue, turn the white squishy fat brown, make it more metabolically active, protect your muscles. T2 acts like an exercise mimetic. So it's just like you're going to the gym. This is what gives us that better metabolism, so that we're burning fat while we're just sitting around doing nothing. So you don't have to starve yourself to lose weight. You don't have to work out three hours a day to lose weight. By adding a Metabolism fixer, you're going to have better appetite control. You're going to have nice steady energy through the day. That's another thing that T2 does bonus. And you're going to have a better overall basal metabolism. The amount of body fat and energy that you are burning at rest. And that is what is going to ignite your metabolic furnace and that is what is going to get that weight off of you once and for all. So if you need better appetite control and you know you just want a better metabolism and you don't want to carry around extra weight, Add in Metabolism Fixer. Just one scoop a day. That's all you need, one scoop a day. It will start kicking in very shortly to control your appetite. Studies show about two week onset, but we've had people notice that appetite control kick in within a day or two. Add in one scoop Metabolism Fixer, you are going to thick. Thank me that you saved hundreds if not thousands of dollars not using A glp, but using this. Yummy. Throw it in your water, flavors your water. Oh, my God, it tastes like Tang. Metabolism fixer every day. Reagan, I'm so happy that you're coming on because, you know, it's one thing to talk about peptides. I have, I would say, like a moderate level knowledge of peptides. But, you know, when you have an expert on and you can really go deep and you can explore different therapies that are out there, that are possible for people, that some. Which we're going to talk about today that I've never even heard of, it just takes people's health to another level. And then the other thing I want to say is I was thinking about that this morning. We live in a world where you say the word peptide and it's just so common. You know, everyone in our space, our followers, our listeners, they kind of know what a peptide is. They might not know all the little names and exactly which one to use for pain or recovery, but they know in general what a peptide is. I had a neighbor the other day talking to me about her osteoporosis and her pain and her sciatic pain. And I mentioned BPC157, and she looks at me like I have five heads. I'm like, well, you know, it's a peptide. But I've never. What is that? I've never heard of that. What are you talking about? And then it dawned on me that these therapies are almost hidden and we need to get them out into the world to people like my neighbor who could benefit so tremendously. But it's not common talk. It's. It's not out there for the general public. And that's what we really need to. To do is to get it out there and to common speak, because these are life changing therapies. So thanks for coming on, man.
Reagan
So happy to be here. And, and yeah, the more that we can educate people on some really great tools and great med, the better. So thanks for all the great work you're doing and thanks for being on my show as well. It was very well received.
Dr. Amy
So much fun. Thank you. I appreciate that. Okay, so let's just open up your brain and start unpacking it a little bit. So let's start with peptides. Before we get to the fascinating therapies that I have never heard of. Let's start with peptides. So, you know, you have a. A woman walks into your office. Let's start with women. A woman walks into your office. Reagan, you know, I'm Just so darn tired. I don't have the stamina that I once did. I just feel like I'm rapidly aging. Things are hurting. I'm not recovering from my workouts. Yeah, I'm carrying that extra 10 pounds I started on those hormones that I hear people talk about, but it's just not taking me to the next level. What do we start with?
Reagan
Well, diagnostic testing. Because then we have to say, well, you know, I'm assuming if someone had their thyroid, looked at their hormones, everything, you know, as long as those things have all been properly assessed, we may do a gut test, run them through functional medicine. But then assuming that now we know what the best pathways are, then you look at peptides and you'd say, okay, well, if someone's tired all the time, then there's four EPIC triggers that we talk about. And EPIC is just an acronym. And so we'd say, okay, what are the emotional interferences in your life right now? I'm no therapist and I don't ever pretend to be, but those things can be big interferences to healing. Big blocks. You know, for energy generation. We look at the p. Is there any pain in your body? And if there's pain, pain can be like that. It's like having a leaky faucet. Like, you just. You lose resources and pretty soon you get pretty burned out, and it's really hard to regulate your energy generation. The I in EPIC is infections, and that's a big one that we find. So let's, let's just assume we found some infections like mycotoxins. You know, everybody's mycotoxic burden is. It's higher now than I've ever seen it. 90% of the people we test have some type of mycotoxin trigger. And it's fascinating, but it's also really scary because most of the time we find it's in people's house. And people spend 60% of their life approximately in their house, and they're just going into an environment where they're getting sick all the time. So then what we would use is they'd say, well, I've done all the treatments for clearing out the molds and the microbiome, mycotoxins. And my house is remediated, and I've got my air purification system and all that. But then we'd say, okay, what peptides can really help? And that's where we'd say, well, we gotta fix the leaky gut. We gotta fix the membranes in the body. And that's where Lorazotide is a really phenomenal peptide because it's actually FDA approved for people with celiac disease. So that if they have some exposure to gluten, like maybe it's in soap or something, they're at a hotel and they wash their hands with soap that's got gluten in it, and they have a flare up. You know, if they have lorazatide, they won't even notice. And so lorazatide is a peptide made in the tight gap junctions of the endothelial cells in your intestines, primarily in the small intestine, but then it does migrate down into large intestine. And that peptide therapy is very well documented. Obviously it's a, it's an FDA approved peptide, but it's a naturally occurring agent in your gut. And we've been able to help a lot of our clients who have food sensitivities and immune triggers by using lorazatide, for example. And for people that don't know what peptides are from a medicinal perspective, I guess maybe I'll back up just a little bit. If you think about how our cells communicate, they communicate through hormones, which is more long term communication networks and the hormone docs, and then every system in your body, there's a feedback loop. So there's a negative feedback loop, there's a positive feedback loop, negative. Reagan's got plenty of testosterone. He just did a testosterone injection, hypothetically. And then my brain would say, okay, we don't need to make any testosterone, because the message is clear that Reagan's got plenty. And those are really important. But then if you think about the more nuanced communication patterns, these are like the text message. And it's like, you know, you and I can text each other really quick, like, hey, I'm looking forward to be on the podcast. I'll see you in five minutes. Right? That's like a peptide. It's short. Peptides are metabolized in seven to 30 minutes. They're very short acting. Some peptides have a longer lifespan, like the GLP1s, which. Happy to get into those. But if you've got the right peptide protocol. Peptides are like little folded proteins. They're just short amino acid chains. We say 50 or shorter. The FDA originally was 60 or shorter, then the FDA lowered it to 50 and now 40. 40. But. But roughly speaking, anything 50amino acid chains or shorter is going to be classified as a peptide. Otherwise it goes into a biologic or a protein. And. And so what these peptides are is they're folded in A very particular way. And they're like a key that unlocks a gene. And if you think about as we age, we lose that ability to communicate clearly in our cells, and then we start to notice a decline in our health. And those interferences. You could live in a moldy house when you're a kid and it doesn't even matter. But then when you get older, it's like, whoa, I can't tolerate mold at all. That was the case with me, for example. But if you can get the right peptides and you start turning on the right pathways so that your body becomes more resilient, that's when you can really express health in a very phenomenal way. And I just found that peptides, when we got into them just over a decade ago, I found that the leverage that was generated, I could get people healthy at what used to take me three years we could accomplish in six months. And that became really, really exciting. But peptides are like a band. It's like, you wouldn't want to hear the Rolling Stones. It was just Mick Jagger. I mean, he's great, but you want to have the other band members there. You wouldn't want to go to the symphony. And it's just a violinist. That would be inspiring, don't get me wrong. But when you bring in the cello and the drums and the orchestra, it's really, really powerful. And so we would use, like, lorazatide. Then we start working on the MSH pathway, the melanocyte stimulating hormone, which a lot of people miss when it comes to mycotoxin illness. And so you can use kpv, which is a bioregulator made in your gut. You could Also use Melanitan, Melanitan 1, or Melanitan 2 if you like being tan. Those are great treatments that all work on that mycotoxin pathway. Then we could add in the reparative peptides like Thymus and Beta 4 and BPC, and people will start feeling better. And then from an immune modulation perspective, that's where, like, Thymos and Alpha 1 is really critical, or even pinelion. And. And so you wouldn't want to throw all the peptides at once, but you'd want to do it strategically. And then what we would see with that client who walked into the office is all sudden, she'll say, well, I'm feeling better. And, you know, we'd have some binders to make sure that she's detoxifying properly. Put her in the sauna, make sure that, you know, she has a mycotoxin free diet. So there's about 15 foods that she'd be eating for, you know, the first couple of months and, and she would just start feeling better and better and stronger and stronger if that was the case. But that's the thing I love about peptides is they're very well tolerated and even people who are super sensitive seem to respond really well to them.
Dr. Amy
Now here's what's blowing me away. I'm thinking as you're talking, all of these people, like you said, gut healing protocols as part of functional medicine and gut testing. Great. They're, they're amazing. And a lot of people do have those GI issues or they have mold issues, you know, and that is the key of what's holding them back from progressing. So many programs out there, just like you said, are maybe a year in length and people don't have the time to take 5 million different supplements and wait that long to feel better. You know, we have a limited time on this earth and let's feel our best as quickly as possible so we can enjoy life to the fullest. That's my motto. So if, if we can do something with people to speed that process along. And you know, I knew that there were peptides out there for gut healing, but honestly all I ever heard of was the oral BPC157 and then that speeds up gut healing. But what I'm hearing you say is there's these protocols that can really speed up the whole healing process and get people to the finish line much faster than these long extended multi supplement protocols.
Reagan
Yeah. And, and I'm by the way, I'm a big fan of, of supplements and sure learned so much from you on supplements. I mean, we were talking about thyroid. I was like, wow, I had no idea there, there's, you know, this T2 that I didn't, I didn't even, was off my radar. And so I appreciate the knowledge you bring on that and so many other things. So this is not to discredit anyone or what people are doing, but I just, I work with entrepreneurs who are very, they're add, but they're also type A and they want, they, they just want the, the results. They don't care how they get there. They, they're willing to do the work. They don't mind injecting themselves. They're not afraid to try new innovative therapies. They don't need to get permission from some like, you know, American Medical Association. If this treatment's FDA approved, all that they realize is ridiculous when it comes to real healing. And what I found is, is if I stacked peptides, the results, it was overwhelmingly more successful than anything else we'd ever done with supplements alone.
Dr. Amy
I love that. I'm going to ask you for, for some stories here in a minute, but I want to keep going with the different peptides. So obviously you mentioned the gut and then the mycotoxin exposure. What about those people that they just want to, for esthetic purposes, look better, look younger, feel younger, have better muscle. And we know that, that hormones, including growth hormone, declines as well. We age. So as a longevity stack, what would you do for, for that person?
Reagan
The first thing I would just quantify is I'd say we call it the ageless axis. And so if you think about the three systems that we all want to work really optimal when we're 100, it's our brain. Nobody wants to get to 100 and, and feel great physically, but they don't know who they are or who their kids are, right? And so that's like, you know, the big component. The second system is your cardiovascular system. Your cardiorespiratory system is critical because it's all the circulatory pathways and that's what nourishes the body. That's how you get rid of toxins. And then the third system is the muscle mass. And muscles inform the brain, they inform the heart as far as what the body can tolerate. And so our bodies can be in, in a very youthful state based on the health of our muscles. And it's not just muscle mass. I mean some, in some cases muscle mass. If you have too much muscle mass, you're going to probably not live as long. But if you have muscle health with the muscle mass and you maintain the fast twitch muscle fibers, that's going to be, there's, there's no way that you won't have a really enjoyable life in your 70s, 80s, 90s. I mean I have clients in their, their 90s. I had one client, lived to be 103 and he was a truck driver his whole life. He had, his name's Eldon and he, he passed away a couple years ago, but he had 128 posterity. So he had his kids and then his grandkids and great grandkids and great, great grandkids. Can you imagine having a, like a family party with 128 people? I mean he was so cool. And he always say, I'd say how are you doing today? And he'd say well, getting old is not for sissies. But it beats the alternative. And the thing about Eldon is he was always working on his truck. He had a ranch that he took care of. He never stopped working. He never stopped moving his body. He was actually really, really strong. I joke around and arm wrestle him because he had like, he had, like, still had some muscle mass. But the thing that we did with Eldon, so that he is his last, you know, decade of his life was actually one of his best decades. And that's one of the things that I love peptide in using peptides for, is so that people don't have that decade of death where they're just basically in a nursing home, like, drooling on themselves, watching the Wheel of Fortune or whatever they're doing in there. But, but Eldon, the thing we had is we gave him peptides like growth hormone. You mentioned, you know, growth hormone declines about 10% or more every single decade of life. And it's substantial because the growth hormone is what allows you to sleep deep. It also allows you to repair and recover. If you didn't have growth hormone, your, your body, you would, you would not have any structural support at all. Like, your joints would fail, your muscles would fail. And so we use growth hormone socratogues. And by the way, there's about a hundred different peptides that relate to growth hormone. And so Everybody knows, like CJC 1295 and IPAmerica, those are phenomenal. CJC is a bit of an intense one because you get such a flushing effect from it. So you do want to be careful with that one, especially if you have immune reactions, like if you have allergies. I would not use that peptide necessarily, but. Tessa marellin is a 43amino acid chain. It was approved by the FDA to treat lipodystrophy in 2010. So these HIV patients and HIV patients, by the way, I mean, muscle wasting is the. I mean, they're aging so quickly. Immunosenescence kicks in. And these patients were losing muscle mass and they're building up this visceral fat that was really toxic. And they were getting fatty livers. And with Tessa Marellin, what they found in there's one study that was 52 weeks, another study that was 26 weeks, and they found with these participants versus the placebo groups, the control group, these, these patients had about a 15% greater loss of visceral fat. And they, they were able to lose that adiposity that had developed in their midsection. And they were able to gain on their lean muscle, they were able to gain like close to 28%, approximately, in the studies. And so the FDA approved it. It goes by the drug name Agrippa. And. But it's. It's a peptide. It's not growth hormone. So once again, it's a short signal to the body, and it tells your pituitary gland, hey, Morgan needs more growth hormones. So when I inject my Tessa Morellin, you want to do it in a fasted state, and you just get this nice, nice release of growth hormone, and so you recover faster, you get in your deep sleep. That's what we use with L. We also use some myostatin inhibitor peptides. So if you think. You think MTOR and ampk, right? That's growth hormone is going to activate mtor, and that activates protein synthesis. You know, anytime you eat protein, you're activating mtor. And everyone's so worried about mtor, like it's going to cause cancer. And that's why rapamycin became such a big drug of choice. But my clients on rapamycin, what I learned about 10 years ago, they. They actually weren't thriving after being on it for a year, and in fact, their immune system started to get suppressed. And rapamycin, for those of you aren't familiar with this drug, it's. It's an antibiotic, but it actually is used as an immunosuppressant drug for people who've had organ transplants. And so we've never used it as part of our longevity protocol. And now a lot of the, you know, kind of the celebrity doctors like Peter Attia and David Sinclair, they're now having second thoughts about using rapamycin. But it does turn off mtor. But you can use another peptide with the growth hormone secretagues. And these peptides are working on the follistatin and the AMPK pathway. One's called MOD sc. And MOD SC is, is a. It's a myostatin inhibitor, which means when you express follistatin, you're going to have massive muscle gains and you're going to feel great. And then there's. The other peptide we use, is called ACE031. And ACE031, in the clinical studies, they took postmenopausal women and they looked at the circumference of their thighs in particular, and these women were losing muscle and replacing with fat. So sarcopenia. And they said, well, let's see, would ACE031 if we did a myostatin inhibitor and just took off the brakes? Because in the body, once again, it's A feedback system. So anytime you push on the accelerator, you could put your body at risk. So you always want to balance the inputs. And so this myostatin inhibitor, all it does is just takes off the brakes because the brakes are already full, fully engaged by the time we're older. We don't have very much Follistatin expression. And so what they found after 60 days of using it, on average, these women, they gained 5% of lean muscle in their legs and they lost 9% of visceral fat. And, and so it's really cool. So if you just think through the lens of all of these different, different pathways and if you can selectively target the pathways at the right time, then they do. You know, two cycles of 60 days a year is really all you need from a peptide perspective to have really healthy, robust muscles where you recover quickly. You, you look better every year, you just get a little more fit. And it, it's not putting your body at risk for cancer or any kind of tumor genic activity.
Dr. Amy
Okay, so just to kind of summarize what you just said there, just so the listeners can grasp it, the, the rapamycin is, is out. I've heard about it, we've talked about it a little bit on the show in terms of just using it kind of pulsing to lower the risk of cancer, prevent cancer or whatever. But you do get that downside of the MTOR inactivation, which is going to decrease your protein synthesis. When I was speaking with Dr. Elizabeth Yirth, she actually brought up metformin as a, as an MTOR inhibitor. And I said, oh my gosh. You know, I was taking metformin in my 20s and 30s, 30s for PCOS and I had a lot of trouble putting on muscle. I mean, that's when I was competing and I was lifting heavy and I was young and did all the protein and all that. And I still had issues putting on muscle, whereas today, and I stopped the, the metformin years ago. I don't even use it as an anti aging protocol like some people do. And I noticed that I'm actually putting on muscles. So you're saying no to the rapamycin, but there are other peptides that we can use like amat, C C to induce muscle, basically change our body comp. As we age.
Reagan
That's, that's it. And yeah, and metformin is really toxic to the mitochondria. And so that's where people get sick on it. They just don't feel great. And so, you know, and you and I spoke about this as well. But for pcos, I mean, that's where you can use, like, Modest C is great. You can even use Tirzepatide or some of the GOP1s. And then you can throw in, like, Kiss Pectin, which helps with the luteinizing and follicular stimulating hormone pathways. And women do really, really well.
Dr. Amy
Wow, that's amazing. There's so. There's so much to this peptide world that I've only scratched the surface. Now I might reel back my comment that I'm a moderate knowledge person on peptides. I might be a little bit below that because you're blowing my mind. We're all looking to support our thyroid naturally, boost our immune system, and just really have more energy. I have found Purality Health. Now, the only problem with Pity Health is that it tastes so good. All of their supplements, from the Mind Boost that I'm going to tell you about to the vitamin C tastes so good, you want to eat it every day. You want to take it every day. It's crazy. I'm addicted to it. I'll tell you more about that. But let's start with the thyroid, something I talk about all the time. As you know, Purality offers a wide range of products that can assist you with thyroid health. But specifically, my favorite is the adaptogenic mushroom. In Mushroom Mind Boost, it tastes like chocolate. I will put Mushroom Mind Boost on a spoon with a little bit of peanut butter, and it's literally a treat. But not only that, it's a liposomal blend of functional mushrooms like Rishi and Cordyceps. Now, Rishi and Cordyceps, they help regulate your body's stress response. We know we need to balance our stress, balance our cortisol. So T3 and T4 can work, and so T4 can be converted, converted over to T3. Then another amazing product to support the thyroid is the liposomal lion's mane. That gives us focus, clarity, cognitive support. Again, bringing down stress. Lion's Mane can help boost nerve function, support your mood, both of which is significantly affected when thyroid levels are imbalanced. Now there's the vitamin C. Ooh, vitamin C for our skin, for our immune system, for adrenal support, oxidative stress reduction. And it tastes like you're eating a starburst. It's incredible. I put in my water and it flavors my water. It's amazing. Since the thyroid is incredibly sensitive to inflammation and cellular damage, vitamin C protection is crucial. And here's the best part. Their patented liposomal delivery system makes all of These ingredients, highly absorbable to your body, is actually using what you're taking. Bonus. Right? So if you're ready to finally feel like yourself again, you want to head to purality health.com forward slash Dr. Amy and enter the coupon code Dr. Amy to save up to 45 off. So you're going to go to P U R A L I T Y H E a l t h.com forward/d r a M I E and use that same code D R A M I e. Get your 45 off because your body deserves more than, you know, just. Okay. Health. Okay. So you mentioned the GLPs. And I love picking people's brain on the GLPs. You know, I mean it's, it's like a divided world out there. There are people blasting and using fear tactics. You're going to go blind, you're going to get cancer. All of these horrendous stories. And I will have patients that genuinely need and would benefit from a GLP even at a microdose. So I want to ask you about that as well. And they are so scared from the misinformation. So can you unpack the world of GLPs as well?
Reagan
Yeah, yeah, because I get irritated with the sound bites on social media. Right. People watch a two minute video. I, you probably filled all these questions every day too where it's like, oh, hey, and they send the Instagram thing and it's like, that's so out of context. And so if you really want to learn, go deep, you know, and this is just, you know, my, my own soapbox. But, but the GLP1s are the most phenomenal breakthrough in medicine that we've seen since antibiotics. And if, if you look at the big threat to society right now, it's metabolic disease. I mean, how many people have diabetes? How many kids? Kids like, you know, if you're African American, if you're Hispanic, if you're Native American, you're 50% of those kids have either prediabetes or diabetes and diabesity. I mean they're walking around and they're overweight and it's like, okay, so we finally found the problem. And GLP1s just so people realize your, your body, every organ system in your body is dependent on this is called a glucagon like peptide. And these glucagon like peptides, they are some of the, the, the best fat burning peptides that you could ever imagine. But what the GLP1 does is it lets your body know when it's Full. So when we were, you know, 100 years ago, we didn't always have food. We did feast and we did famine. We ate as much as we could because we didn't know where the next meal was coming from. And then we'd have times of fasting and starvation. These days you and I could get food right now. We could just make a phone call and we'll have food here in five minutes. Crazy, right? And, and so our, our GLP1 mechanism broke and it's, it's, it's really not people's fault because what, what also breaks it is all the artificial junk and foods, it's all the chemicals that were exposed to. It turns off the signaling. And the thing I love about peptides is it's just fine tuning your cell's ability to communicate again. So I have a client and he's, he makes movies, you probably know him. And he was struck, he's here in Utah and he was struggling with weight loss. He actually had a live in trainer and a live in chef for a year. And he spent a fortune just saying, I got to get my weight off. And he got down to 185 5. And he's short and he's got a small frame so his ideal body weight is closer to 135 pounds. So he was still about 50 pounds overweight. And it wasn't until we got him on tirzepatide that he actually started making the changes. And now for the last three years, he looks better, he feels better, he's healthier than he's ever been. And his kids have the same genetic propensity where they just don't produce GLP1 ones. And now his kids are on it. His kids are doing great. There's, it wasn't that he had a lack of discipline, he didn't have a lack of a strategy. He'd done all the diagnostic testing, but that mechanism was still broken. And, and this is what we see time and time again. The, the real criticism comes to the way the pharmaceutical companies have taken a really good, good substance, we'll call it these peptides, GOP1s. And they said we can make a drug out of this. And everyone's like, well how can you patent something as natural where they patent the administration of it and the administration of it is a much higher dose than what Amy or I would ever prescribe. And they're dosing it with the intention of you being on it for life. And that's the real danger, is you want to cycle off any of these peptides, no matter how good they sound, like Ace31, you're like, if they lost all this fat and gain muscle in 60 days, I'm just going to stay on it the rest of my life. So I'm always building muscle. There's diminishing returns, and you got to work with somebody who knows what they're doing on peptides so that cycling is appropriate. And GLP1s, because the dose is the poison. If you overdo it, then you will lose muscle mass. And by the way, even if you have healthy weight loss and you lose 50 pounds, you, your body compensates, it doesn't need muscle is very energetically demanding for the body. And your body's, it's the law of entropy. I mean, you can't, you can't argue with the laws of physics. Law of entropy is our body wants to be as efficient as it possibly can. And as you know, you're, you're, you know, you're, you're a bodybuilder. You know that it takes an enormous amount of work to get the physique that you want. And you can't. You, I mean, it's not sustainable to be at stage ready every single day. And it's not healthy healthy either, right? And it's, it's no different with GOP ones. Like, you've got to cycle on, cycle off just like you did, you know, cuts and then you do refeeding. It's no different. But GOP ones, once again, we would never use a peptide. Just single, like a single peptide. You're kind of wasting your money. A lot of people come and they're like, I tried bpc. It didn't work. I was like, well, did you add Thymus and beta 4 with it? Did you had a growth hormone peptide with it? Okay, well, you're, you're only getting like a, a little fraction of the signaling that is needed to make the complete transformation. So any of you using a GLP1, make sure that you're adding in BPC157 because it slows down the gastric emptying. You're full, you get full fast. You may get acid reflux. So BPC will help mitigate that. Make sure your detoxification pathways are open, use binders, use detoxification agents, eat really well. Exercise. You gotta exercise when you're on these, because what GLP1s do is they actually create more insulin sensitivity. And you've known bodybuilders that are not natural. And one of the things they do before they get on stage is high doses of insulin. It's an anabolic hormone. It's the most anabolic hormone in the body, but it creates more insulin sensitivity. So you can actually build muscle on GLP1s. Studies also find that GLP1s are really good for addiction. And what Jeff told me is like, you know what, Reagan? I don't even like the taste of wine anymore. And he's got this massive collection of gorgeous wines. And it's like, good, good. That's. That, you know, a bottle of wine a day is not really part of the longevity plan that we have for you.
Dr. Amy
Well, that's true, too.
Reagan
Right. I love wine. Don't get me wrong. Like, a little bit of wine is fine, but. But you also want to look at the growth hormone. You talked about growth hormone peptides. Like, it's really important to have those in so that when your body is. Yes, when you've turned off MTOR and you've activated ampk, your body goes through autophagy. And you want autophagy, but then you want to build on. On top of that. So it's like, it's this. It's this beautiful harmony that the peptides provide where it's just subtle inputs because your biology is so sensitive. And a lot of us, we forget that you don't need to just, like, shake your body and like, try to force it into a pathway. You can just gently work with it. And that's one thing I love about peptides, is it's just small, little doses, little micro doses. And over time, you see these traumatic changes. GLP1s just so everybody knows we're finding more and more things out about them that we never realized they could treat osteoarthritis in the knees. One of the studies they found is, and it was published in the Journal of American American Medical association last year, and they found that the proteases that drive osteoarthritis were turned off when people use GOP1s. And they proved that it wasn't just because they lost 30 pounds and now their knees are doing better. It was actually different because other. The control group lost weight and didn't have the same. They still had the osteoarthritis GLP1s for kidney failure. We have a lot of clients. For some reason. I have a lot of people with kidney disease that come to see me, and we find that we can reverse their kidney disease by getting them on GLP1s and then other peptides like SS31 and Humanin and some of the mitochondrial peptides like sloop. But, but the thing about these GLP1s is the new one that's coming out is called HA9,31. And so we have, we have semaglutide, which is just GLP1. It's a single agonist agonist, meaning it like causes more production of GLP1. Then we have tirzepatide, which is a dual agonist, so it's a GIP with the glp. And then we have retatrutide, which I love, which is more of a performance enhancement because it's got glucagon in there, which your liver loves. Just a little pulse of glucagon. So for those of you who want to like really increase your performance and not always be hungry man, reditrutide is a game changer. And there's a new, the new drug that you'll see coming out called HA931. I don't know what they're going to name it. I'm sure they'll spend a fortune naming this thing. But, but it's got the triple agonist, you know, serratotrutide plus IGF1. So the IGF1 LR3 peptide, which was, we've been using it like that for 10 years. And so it's so cool to see that they're finally connecting the dots. Like, oh, more peptides is better. It's not, it's not a single treatment. It's not a small molecule drug where you're just trying to isolate one pathway, suppress a symptom so that people feel better and get out of your office now. They're actually thinking of a complete transformation.
Dr. Amy
Now. Is that available as a peptide right now? You know, just like the drug companies took semaglutide as just, hey, it's a peptide. Let's put a drug name on it and charge $1000 a month. Is that HA peptide a peptide now that we can start using or do we have to wait for big pharma to bring it out?
Reagan
No, we, we can start using it. We've got one of our pharmacies that are compounding it all together. So it's, yeah, it can be used. It's not, it's nothing magical. It's just like, oh, let's just compound them together. But the thing that they've done is made it orally available and that's novel. And then the way that they're getting it to market is they're finding that it, it outperforms any other treatment for alcoholism. So they're bringing it on not for weight loss. So they are making it like weight loss without the muscle loss. But. But the, the real fast track is going to be alcoholism. Cool.
Dr. Amy
Amazing. Going back to not wanting wine. Exactly. So with these GLP sticking with this topic, is there a way to test. You had mentioned that some people just naturally don't produce enough GLP on their own. And, and it's a. Whether it's a genetic issue, like it was passed down in, in a family, or you're just, you were just doomed to have this little snip where you don't produce enough. Is there a way to test for that?
Reagan
Well, the big test you want to look at is there's, there's. Genetically, there's so many different pathways that can trigger the expression of GLP1. So I couldn't just say that there's just one singular pathway that, that, that I know of that's been isolated. Now, someone may already know that, and I just haven't learned it. But what we test is we'll look at the hemoglobin A1C. We'll look at insulin, fasting C peptide and LDH. And those markers are very reflective as to if somebody needs GOP1s or not. You'll also see people who have hypoglycemia and people who have adhd. It's very interesting because you can actually use it, if you use it correctly and it can correct hypoglycemia. And you'd think, well, I thought it was lowering blood sugar, but actually, if you make sure that people are eating properly, it changes the whole structure of your digestive system because things get a little slower. And, you know, you and I both work with a lot of ADD ADHD types, and they're the funnest people in the world, but they, they have really crappy bowel. I mean, they're going to the bathroom four or five times a day because just as their brain is so fast, their gut's doing the same thing and it's a reflection. And so with these GLP1s, we've had clients who've had loose stools their entire life, and they are, like, shocked because, like, I'm only going once or twice a day. Is this normal? And I'm like, well, what's the bulk? And are you. You know, you feel satisfied when you're done? And yes, everything feels great. It's like, that's a normal stool. Congratulations. One of the Chinese emperors, he said, happiness is a cup of tea in a bowel movement. So now you can be happy. You got no excuse.
Dr. Amy
That's so true. And while I'm even thinking about the implications on Crohn's disease and ulcerative colitis, I mean, it's just overall healing is. Is tremendous. And the other thing I've noticed, I'm wondering if you have an improvement in mood. I mean, literally, people not needing antidepressants or people that just really didn't want to go on antidepressants and happen to start a glp and they're like, wait a minute. I am in a fantastic mood. My anxiety is down. There's something that shifts in the brain.
Reagan
Yes, we, we. We see that as well. Like, you just. It's a bit of a nootropic because once again, you have energy that's able to get into the cells of the brain. So, you know, you think of Alzheimer's as type 3 diabetes. It's like insulin resistance in the brain. You don't. It's an energy deficit. And so when you've got energy in the brain, you're like, wow, this is cool. And I'll give you a little, little hack. One of my favorite peptides is tessofensin, and it activates dopamine, serotonin, a little bit of epinephrine, and it also turns off the appetite. So when you cycle off GOP1s, you can use Tessa Fencen if you, if you have that voice in your ear that's always wanting you to eat it, it subdues the voice, but it puts you in this flow state that's really powerful. And you can use them in. In conjunction with each other too, where you just. You're in the pocket and you can use it every other day. It's got a little longer half life. But a lot of my clients love Tessa Finsen as well.
Dr. Amy
Oh, so much juicy information. I love this. Okay, this is fantastic. Well, here's what I'm thinking, too, as you're talking. I'm going to become a patient because I want you to lay out a plan. There are so many peptides that I have never heard of. And now we're going to be stepping into this other world that I haven't heard of that I'm going to ask you about in a second. But I love how you really get into what exactly the person needs. And, and how can we use these all together to help. Like, one will help the other and one will be helping the body when the other one isn't being used. Like you said with Tessa fencing and the Glp so this is just fascinating. I mean this can up level people's health more than I ever imagined, quite honestly.
Reagan
Well, all we're doing is working with the biological pathways, right? And, and we know the mechanism of action. Like you know, you study pathology, pathophysiology, physiology, biochemistry and all sudden you're like oh, there's all these, these cool little mechanisms that happen based on peptides in your body. And so that's, that's where it's, one of the most fascinating areas is exercise mimetics. Because now the, the drug companies are like okay, we can help people lose weight now we got to exercise for them. Which I think is slightly comical because by the way you can't out peptide poor lifestyle. Like we've, I mean we, I do have some clients who, they're like look, I'm not, I don't want to do anything. Just give me what I need. I'm not going to make change. I'm going to keep smoking my cigars, drinking my whiskey and I'm like all right, if that's what you want to do. But the nice thing about peptides is you don't have the same cravings. And so even if they don't want to make changes, they still do and they just feel better and they get younger. But you get the highest benefit when you just do the lifestyle, exercise, eat great, have, have a good positive outlook for life, have some great relationships, give people hugs, things like that. But these exercise mimetics, MOD SC is a big exercise, exercise memetic and I mentioned that earlier, is a, it's a myostatin inhibitor but it's expressed from the satellite cells in your skeletal muscle. And in one of the studies they looked at people, they had these, the, the group exercise and they tested C levels before the exercise and then they had them do 20 minutes on a bike, stationary bike, at kind of a moderate intensity. And then they looked at, at the expression of mot C afterwards and it was 4 to 500% greater. This peptide was, was expressed and that persisted for about five to six hours. And then they also realized it's the heat shock proteins that activate MOT C and so they found the same thing in a sauna. And then they took old mice and they said how far can old mice run on a treadmill? And they compared it versus the young mice and the young mice could run roughly twice the distance. And before petering out the old mice, when they got the MOT C injection seven days later, they put them back on the treadmill and they could run just as far as the young mice. And so that's one of the, you'll see this treatment come out pretty quickly. But some people have immune rejection with this peptide because it's a protein. It's a, you know, it's a protein that your body has to sense. And so if you're not doing it naturally, actually there is a risk profile. So they're, they're eliminating that risk profile. And, and you'll see it come out. But there's SS31, which is another mitochondrial peptide that works like an exercise memetic. And in, in the studies, what they found is not only do, do people have better endurance, but their cardiorespiratory system, the VO2 Max, goes up by about 5%. I mean, it's, it's a really cool world because what we're doing is we're taking the expression that you have when somebody has this very optimal level of health. And we're finding what does the body, what are the proteins and what are the peptides that the body releases when someone's in an optimized state. And then we're just bringing that into medicine. I mean, it's just, it makes perfect sense. But we haven't had the technology, we haven't had the ability to isolate these peptides until recently. Recently.
Dr. Amy
Such a fascinating world. That's incredible. Exercise memetics. Absolutely amazing. Okay, so up leveling just a little bit. Now. I have heard of stem cells. I've heard of exosomes. I have not gone deep down those rabbit holes. The, the most I know about stem cells is that they were highly debatable. Michael J. Fox came out and fought for him for treatments of Parkinson's. My dad's had him injected into his ankle and yeah, they definitely helped. He needs another round done. Exosomes are a whole new world for me that I just started kind of getting my brain into. And then you mentioned plasma renewal therapy. So can you break those down for us? Like, who would use them? What do they do? How do they benefit?
Reagan
Yeah. So stem cells, just to give people a rough definition, is these are primordial cells or, or original cells in your body that don't have an expression cell. So you have 220 different types of cells in your body. And when those cells die, you have a stem cell that takes the place of that cell that died so that you. Otherwise we'd be dead pretty quick. If you didn't have stem cells to replace the dying cells. Every, every breath you take, you're losing About a million cells. So. So breathe cautiously. No, don't. I mean, it's. It's fine. But stem cells can be derived from your own body. But as we age, just like, you know, it seems like the universe stops carrying after about the age of 35. And. And we don't make the stem cell population, we don't make the growth hormone, the testosterone, all the. All the peptides. You know, the signaling starts to get muted. But what researchers found is, is where is the best source to get stem cells? And one reason why it was so hotly debated is researchers were looking at embryonic stem cells. And, you know, you go back to. To Dolly, the sheep that was cloned, and everybody got all freaked out. We're going to have biological clones of humans walking around. Now we just have AI clones. And that's creepy enough, right? But. But what they realized is if. If you have these embryonic stem cells, they just want to create a baby, and they replicate so fast and they cause cancer. And then there's the moral implications. Even though they're using, like, these embryos that were going to be discarded anyway, people were just like, that is life and don't use it. And so the Bush era just kind of terminated a lot of the funding, federal funding anyways, for stem cell research. But what researchers discovered is in the umbilical cord, there's a part of the perivascular region, so the blood vessels that run through the cord. That's where you have this dense supply of mesenchymal stem cells. So these are lower down the totem pole, essentially, actually. And these. These cells are just signaling cells, and they listen to what your body needs, and then they send these little microscopic. These vesicles called exosomes. And exosomes are like the. The signaling factors that allow the body to start producing its own stem cells. The stem cells is just the intelligent factor. It's like a. Arnold Kaplan, who named stem cells. I had the chance to meet him, and I've spoken on stages with him. He's. He's like the godfather of stem cells. He. He named them medicinal stems, medicinal signaling cells. They were mesenchymal stem cells, but he said they work more like. Like your body's own pharmacy. And so we've been using umbilical cord stem cells for 14 years. I did it because I had a rotator cuff tear that I didn't want surgically operated on, and I didn't want to use stem cells from my own body because I grew up on a cattle ranch in Idaho. So I had Hashimoto's. I got into natural medicine because of my own autoimmune disease with my thyroid. And I said, well, the thing that triggered it was all the. All the herbicides and pesticides and formaldehyde I was exposed to working on a ranch. And so I said, I don't want to use my own. Stem cells are contaminated. But we did find that in the umbilical cord, there's these dense supplies of stem cells. And so when we injected my shoulder at the time, it was very expensive, and nobody was doing it in Utah. Everyone thought I was crazy. My doctor at the time, she was like, I don't. You're gonna sue me. And I was like, no, no, this is fine. And so I was like, give me a break. But we did it. And my shoulder recovered after three months. I could do pull ups again, push ups. And this. This tear was severe. I tore the other rotator cuff skateboarding with my boys a few years later, stem cells fixed it. And then I tore both rotator cuffs four years ago, skiing. And when I got the. The mri, the radiologist who I'm friends with, he's like, hey, Reagan, I didn't know you had surgery on your shoulders already. I can see surgery on both sides. And I'm like, I never got surgery. He's like, what? I was like, that's stem cells. So it actually, you could see where I had a 4 centimeter thick tear in my structure. Supraspinatus on the right side and then a 5 centimeter tear on the left side. Full thickness tears. And they both recovered, they both repair. And you can see it in the mri where it looks like a surgical. Like a suture that was almost placed there. So stem cells work. We've done 25,000 cases in Utah. We got a law passed Senate Bill 199 for those of you who want to look it up. Last May, May 1, it went into almost a. Exactly a year ago. We have. That protects us in using these types of stem cells as long as they haven't been manipulated. So. So that's stem cells and they can work. We do it intranasally for the brain, which is phenomenal. We do it systemically, intravenously. So these stem cells will hone in on areas that are damaged, and they'll help correct the problem before it ever becomes symptomatic. And then there's great things we can do for the skin, for the hair. There is sexual rejuvenation. We do it for, you know, in the penis, in the labial folds. I mean, it's, it's a phenomenal treatment. Clitoris.
Dr. Amy
Yeah.
Reagan
I don't do the treatments, but Dr. Steinle does, and she's phenomenal at the injections. But stem cells are very safe, very well known. They aren't perfect. If you want to get induced stem cells, there's some really cool stuff. The, the Terasaki Institute out of. They're connected with ucla. They're actually growing entire organ systems from patient stem cells that will be FDA approved soon. Tim Nelson, who's a friend of mine, he's got the first study where the FDA is allowing him to go in and you, you take these, these babies who have heart defects, and they can take stem cells from the baby when they're in the womb, and then right. When they're. They're born, they would die. But he's able to inject their own stem cells and now. Right. Repair the heart from birth defects. So phenomenal. I mean, saving lives. And, and we're also working with the Mobigdalia Clinic down in Argentina, and they, they stack stem cells with the white blood cells so that your body doesn't reject it. And you can grow cartilage tendons. They're helping quadriplegics walk. And it's, there's. It's just science fiction is what it felt like in the past, but now it's reality. And the. It's only a matter of time before the fda, we bring some of these more advanced treatments into the United States. But for now, like these, these stem cells, you know, we can't treat diseases with it, but the FDA has recognized that, okay, it's a viable treatment. And our medical boards in most states, Florida, I think it was Florida that took on the same, they adopted the same policies. Utah did, I believe Colorado is doing it, Texas is doing it. But these stem cells are very safe, very effective. But if you really want to get into, like, reversing disease, then that's coming down the pipeline.
Dr. Amy
So we don't necessarily. Right now, let's say for a rotator cuff tear or an mcl, we don't have to travel to a different country, but we do have to go to the specific states. Like you're based in Utah. We have to go to those specific states to get that, that, that treatment.
Reagan
Actually, there's other doctors in other states still use these stem cells, but they don't have protection. The FDA wrote me letters and they were like, please don't talk about this. We had so many great research papers and testimonials. And everything. And they asked me to take it all down. And so now we're protected where it's like, hey, you know, we're not treating disease, but we're seeing. These are the results, these are the outcomes that we're seeing. And it gets better and better. So when I first got my shoulder done, we were excited to have 1 million live MSCs post thaw because there's a high attrition rate when you cryogenically freeze these. These tissues. Now we're seeing 40, 50 million. And so, and the price is about three times less. So, yeah, you can get your joint done for like, 2,500 now, and mine was 8,500 when I first did it, and it's so much better. So, yeah, these things, it's really exciting. And some doctors are doing it and they do run a risk, but. But, yeah, as long as you recognize it's not going to be permanent. Like your dad, you mentioned, with his ankle. Yeah. You may have to repeat the treatment every year. That's amazing. Being out of pain for a year, when you've got arthritis or when you've got a severe injury, like, that's massive.
Dr. Amy
Yeah, yeah, no, I totally agree. So now I'm thinking stem cells like the Porsche. What about these plasma renewal therapies? Is that. Is that kind of like a Toyota, or is that still up there?
Reagan
It's. It's like a. So plasma renewal. If you think of the plasma in our blood, it carries all these inflammatory cytokines, and as we age, we don't clear the waste out of our blood, and it disrupts signaling. It stops our nutrient sensing and all the hallmarks of aging start in the blood. And so what people do is plasma exchange. And they'll go and they'll get hooked up to a dialysis machine and they'll pump all of their blood out and they'll separate the blood from the plasma, and then they'll pump in, usually albumin and some saline, you know, so that you have the right quantity of fluids in your body. But that's. That's how they've done it. And I. I was talking to one of my friends who's big into plasmapheresis, and he just talked about the complexities of it, the risks. And I was like, I want to do this, but I don't want to do it because it's too risky. And so I looked at research, and I found that there's a study where they use concentrated cord plasma from the umbilical cords, and they separated it out and Then they, they did weekly injections of concentrated cord plasma for 10 weeks. They looked at, at all the biomarkers, they looked at the grimage, they're looking at the methyl groups on the DNA. And what they found after 10 weeks is these patients had the same response from a frailty perspective and an objective biometrics analysis as the patients who did the plasmapheresis. And so we've been doing that for about two years now. And all it does is it clean. It's like an oil change for your blood, but you don't have to, have to get the dialysis. And so it's, it's been a really cool breakthrough. And it's a fraction of the cost. You know, I grew up on a farm, so I'm very resourceful, and I'm like, well, yeah, what can we do? That's, that's very safe and easy, and this has been just a great breakthrough.
Dr. Amy
Oh, yeah. So that sounds totally different. Like you're gonna hit different goals with the plasma renewal therapy than you would with the stem cells. Just totally different. Both, maybe Porsches, but totally different styles.
Reagan
Yeah. One is like, let's get your oil changed in your Porsche. The other one's like, let's, let's get the engine tuned up in your por. Let's, let's turn you from a Corolla, Toyota Corolla to exactly.
Dr. Amy
I love it. I love it. Oh, these are rabbit holes that I've not gone down. So I, I, I'm so fascinated. So fascinated. So can, can you end with a story? Give me a good. Now, you talked about Jeff, you talked about Eldon. Give me, give me one more story to leave the people fascinated with.
Reagan
Oh, man. Well, you know, the biggest thing that, you know, we started with the brain today. And so, you know, I had a patient of mine who, she was a hockey player, and she got a concussion, and she sat up for three months, followed the protocol, and she's on the Canadian Olympic team. And then she got knocked out again right after she got put back in. And she, for six months, she just was like, she had migraine headaches. She couldn't leave. She was paranoid. Her dexterity was gone. She just thought her career was over. And then she flew in from Canada and we did intranasal stem cells on her. And you know her, one of the doctors that we treated that brought a bunch of patients over from Canada said, hey, I got this patient. Can you help? And I'm like, yeah, well, we'll do our best. Sounds pretty severe. And three days after we did the procedure, she flew back to Canada and she called and she said, hey, I can run again, I can ice skate again. She was thrilled. And then she was able to get back. The coaches said, well, you got to make the team. She made the team. Not only did she make the team, she made the Olympic team. And that was really exciting because her life was basically, basically built around her brain and her ability to play hockey. And we've seen, with the, with the brain treatments, we've seen patients who have very severe trauma, ptsd. They're now able to get their motion emotions under control. We've seen clients with strokes who get their dexterity back. It's a very exciting way. And it's just a nasal mist. I mean, it's very simple, simple, non invasive. And then you just get all these, these beautiful molecules. Every time you get stem cells in their natural state. We, by the way, we don't use any stem cells from mothers who have had the COVID vaccine, just because the spike proteins can get into the umbilical cord. But when you do, the stem cells in the brain, they bypass the blood brain barrier. So you get all of the healing properties. You get 261 naturally occurring peptides, you get all the exosomes into the brain. And then stem cells will migrate to the places of the brain that are inflamed, and they'll calm down the microglial cells so that your neurons can start connecting again. And that's probably been the most magical thing where I've seen grown men cry because they said it's like you turned off that avalanche that was always going in my brain. Things are quiet again. And so. So, yeah, I think hopefully that's a good story, because if your brain's not working well, if you have trauma there, if you've had mycotoxin exposure, Lyme, it gets into the brain, everything affects it. And if you can heal your brain, your body can heal much quicker.
Dr. Amy
Well, and I could even do it as a, as a preventative, because I'm very open about. My mother passed from Alzheimer's. Her father passed from Alzheimer's. I have the APOE4 gene, so I could do that as a prevention.
Reagan
Oh, no doubt. I have the APOE4 gene as well. And I do it every year. First, I was the first patient outside of a clinical trial to do it. Arnold Kaplan was the one that shared the research, told me exactly what they were doing in their research setting. I'm like, I'm going to go do it in the clinic. I didn't tell him that, but it was amazing. I have had six concussions and it was when I started writing books, creating medical curriculum. I could. I. It just changed my life. And that was 11 years ago.
Dr. Amy
Amazing. That's so amazing. So, Reagan, I'm gonna come out and be a patient, but can you let everybody else know how they can get in contact with you if they're interested too, in, in, in coming out and seeing you or just working with your team?
Reagan
Yeah, you can go to agelessfuture.com and click on the link. We have, you know, an exciting opportunity for you guys to get treatments. If you want to get peptides, make sure you run all your blood work and all your diagnostics through Dr. Amy. And then we'll collaborate together and help build a peptide protocol for you.
Dr. Amy
That's amazing. So great. So we'll put all of that, of course, in the show notes and all of your social links and everything. So thank you so much for coming on the show. You've. You've blown my mind and I know that this is going to be just a tremendous learning experience for the listeners as well. Just up leveling your health and anti aging, man.
Reagan
My pleasure. Thanks so much for having me.
Dr. Amy
Thanks, Reagan. The information shared on the Thyroid Fixer Podcast is intended solely for informational and educational purposes. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult with your physician or other qualified health care provider with any questions you may have regarding a medical condition, treatment or before making changes to your healthcare regimen, including medications, supplements, or other therapies. Use of the information provided in this podcast does not establish a doctor, patient, or client provider relationship between you and the host or between you and any other healthcare professionals featured on the show. Any medical opinions or statements made by guests are their own and do not necessarily reflect those of the host or affiliated parties. Statements regarding dietary supplements or health related products mentioned in this podcast have not been evaluated by the fda. These products are not intended to diagnose, treat, cure, or prevent any disease. Some episodes of the Thyroid Fixer Podcast may include sponsorships or affiliate links. The host may receive compensation for discussing or promoting certain products or services. Any such sponsorships or affiliations will be clearly disclosed during the episode. All opinions expressed are those of the host or guest and do not necessarily reflect the views of any sponsors. The inclusion of a product or service does not imply endorsement by any healthcare professional featured on this podcast.
Podcast Summary: The Thyroid Fixer Episode 527
Title: Mindblowing Therapies to Fight Aging, Lose Weight and Heal the Body (sometimes without surgery)
Host: Dr. Amie Hornaman
Guest: Reagan
Release Date: May 23, 2025
In Episode 527 of The Thyroid Fixer, host Dr. Amie Hornaman delves deep into advanced therapies aimed at combating aging, facilitating weight loss, and promoting overall bodily healing without the need for surgical interventions. Joining her is Reagan, an expert in peptide therapies and regenerative medicine, who provides invaluable insights into cutting-edge treatments that can transform health and longevity.
Peptides are short chains of amino acids that play crucial roles in cellular communication and various bodily functions. Reagan explains their significance and application in modern medicine.
Definition and Function:
“Peptides are like little folded proteins. They're just short amino acid chains. We say 50 or shorter. The FDA originally was 60 or shorter, then the FDA lowered it to 50 and now 40…” ([07:59])
Types of Peptides:
Benefits of Peptide Therapy:
Reagan highlights how peptides can significantly accelerate healing processes.
“When we got into peptides just over a decade ago, I found that the leverage that was generated, I could get people healthy at what used to take me three years we could accomplish in six months.” ([07:59])
Glucagon-like peptide-1 (GLP1) therapies have emerged as groundbreaking treatments for metabolic diseases, particularly obesity and diabetes.
Mechanism of Action:
GLP1s signal the body to recognize fullness, thereby reducing appetite and aiding weight loss.
“The GLP1s are the most phenomenal breakthrough in medicine that we've seen since antibiotics.” ([29:43])
Types of GLP1s Discussed:
Addressing Misconceptions:
Reagan emphasizes the importance of proper dosing and cycling to avoid muscle loss and other side effects.
“The real criticism comes to the way the pharmaceutical companies have taken a really good substance, we'll call it these peptides, GOP1s…” ([35:47])
Success Stories:
A client struggling with severe weight issues saw transformative results with tirzepatide, illustrating its potential beyond traditional methods.
“He was still about 50 pounds overweight. And it wasn't until we got him on tirzepatide that he actually started making the changes.” ([29:43])
Stem cell and exosome therapies represent the frontier of regenerative medicine, offering solutions for a myriad of conditions.
Stem Cells Explained:
Mesenchymal stem cells from umbilical cords are preferred over embryonic stem cells to avoid ethical dilemmas and cancer risks.
“These stem cells are just signaling cells, and they listen to what your body needs…” ([48:02])
Applications and Benefits:
Notable Case Study:
A hockey player recuperated from multiple concussions and returned to elite performance levels through intranasal stem cell therapy.
“Three days after we did the procedure, she flew back to Canada and she said, hey, I can run again, I can ice skate again.” ([59:05])
Plasma renewal therapy focuses on cleansing the blood of inflammatory cytokines and other waste products that accumulate with age.
Traditional Plasma Exchange vs. Concentrated Cord Plasma:
Traditional methods involve dialysis machines and are risky, whereas concentrated cord plasma injections offer a safer, cost-effective alternative.
“It's like an oil change for your blood, but you don't have to get the dialysis.” ([58:26])
Benefits:
Research Insights:
A study demonstrated that concentrated cord plasma injections produced similar benefits to traditional plasma exchange but with fewer risks and lower costs.
“They found after 10 weeks is these patients had the same response from a frailty perspective…” ([58:26])
Reagan shares several compelling stories that highlight the effectiveness of advanced therapies:
Hockey Player Recovery:
A former hockey player with multiple concussions regained full cognitive and physical function through intranasal stem cell therapy, enabling her to join the Canadian Olympic team.
“Three days after we did the procedure, she flew back to Canada and she said, hey, I can run again, I can ice skate again.” ([59:05])
Rotator Cuff Repairs with Stem Cells:
Dr. Amy herself underwent stem cell treatments to repair severe rotator cuff tears, achieving full recovery without surgery.
“When I get the. So these things, it's really exciting. Being out of pain for a year…” ([56:27])
Metabolism Fixer Success:
Users of Metabolism Fixer reported significant appetite control and metabolic rate improvements, aiding in effective weight loss without the need for extensive dieting or exercise.
“Just one scoop a day. That's all you need, one scoop a day. It will start kicking in very shortly to control your appetite.” ([07:03])
Episode 527 of The Thyroid Fixer presents a comprehensive exploration of innovative therapies that extend beyond traditional medicine. From the nuanced applications of peptides and GLP1s to the regenerative promises of stem cells and exosomes, Dr. Amie Hornaman and Reagan shed light on transformative treatments that can significantly enhance quality of life. These insights empower listeners with knowledge about cutting-edge options to combat aging, manage weight, and heal the body holistically.
Notable Quotes:
“Peptides are like little folded proteins… if you can get the right peptides and you start turning on the right pathways so that your body becomes more resilient, that's when you can really express health in a very phenomenal way.” — Reagan ([07:59])
“The GLP1s are the most phenomenal breakthrough in medicine that we've seen since antibiotics.” — Reagan ([29:43])
“It's like an oil change for your blood, but you don't have to get the dialysis.” — Reagan ([58:26])
“These therapies are almost hidden and we need to get them out into the world to people… these are life changing therapies.” — Dr. Amy ([07:03])
Additional Resources:
Note: The information provided in this summary is for educational purposes only and should not replace professional medical advice. Always consult with a healthcare provider before starting any new treatment.