← The Thyroid (and Hormone) Fixer Podcast: Thyropause, Menopause, Metabolism and How to Fix It
The Thyroid (and Hormone) Fixer Podcast: Thyropause, Menopause, Metabolism and How to Fix It
618. The Dark Side of GLPs Nobody Warned You About (Muscle Loss + Hair Thinning)
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The bottom line is that people are losing weight. But what no one on Instagram is talking about as they're trying to sell you into their GLP1 program for 129amonth. Thank you, Serena Williams. Is that you're not just losing fat, you might be losing muscle. Well, you are. You are losing muscle and you're losing hair. Welcome to the Thyroid and Hormone Fixer podcast. If you've been told everything is fine, but you're gaining weight despite doing all the right things, struggling with brain fog, mood swings, low libido, or feeling like a stranger in your own body, you're in the right place. I'm Dr. Amy, the thyroid Fixer, and I want you to know right now, I see you, I believe you, and you don't have to figure this out alone anymore. We're going to do this together. But I'm also not here to play nice with bad medicine or empty promises. This show is meant to disrupt the entire health space. We're going to challenge the status quo, connect all the dots other providers miss, and give you real, practical science back. Tools you can use. Today. You're not going to get any more recycled biohacking advice, just truth, strategy and hope. Let's get you back to feeling like the badass human you're meant to be. If you are exhausted, gaining weight, you have brain fog, you just feel off and you're tired of doctor hopping and wasting money. Listen closely. So many women bounce from provider to provider, trying supplements, protocols, and then functional approaches that never truly address the thyroid. Months turn into years and you're still stuck feeling like garbage, wasting your precious life. So this is why we offer a thyroid and hormone solution call. It's not a lab review. It's not treatment. It's clarity and strategy to determine whether you're a good fit for working with our clinic. We specialize in thyroid optimization and hormone optimization together because they go hand in hand. You can't do one without the other. You have to do them both. We prescribe in all 50 states, and if you become a patient, we take care of you from start to finish. Testing, treatment, optimization, and ongoing support. You don't have months or years to waste feeling this way. And you shouldn't have to keep throwing money at people who don't truly understand the thyroid and hormones. So if you're ready for real help, go to drami.com that'S-R-A-M I-e.com and click book a call in the top right corner to schedule your thyroid and hormone Solution call and just let us help you get your life back and be that badass human that you are meant to be, that you deserve to be. Okay, ladies, are you in your 40s or 50s like I am and possibly wondering why your energy is just fell off a cliff? Well, you're not imagining it. And it's not just thyroid and hormones. A huge part of midlife fatigue happens deeper, like at the cell level because of your mitochondria. We talk about this all the time. Your mitochondria, those parts of your cells that make energy and it naturally declines with age. So I totally noticed this myself. Turned 52 in February. And of course my labs look good, I'm optimized, but sometimes I just don't feel like the same person, energy wise. So I started taking Mito Pure gummies. My friend told me about it. I'm like, okay, let me try it. And. And it's a gummy, so it's not another pill, which is nice. So Mitre Pure Gummies from Timeline Nutrition. These little bad boys have the clinically proven form of urolithan A, which, that's a whole big science word, right? But basically what uran is, is it helps to renew your mitochondrial function. And remember your mitochondria, key driver, healthy aging, strength, stamina. And it's just simple. It's two gummies in the morning. So no more pills, no more supplement fatigue. Plus they taste good, so you're going to want to pop the gummies in the morning. It feels like I'm supporting my body at the root instead of just chasing symptoms with more caffeine or nootropics. Think of MIT Pure urolithin A as helping your cells make energy basically the way they used to back in your 20s and 30s. So if you are experiencing midlife fatigue and it's dragging you down, this is a great place to start. Go to timeline.com T I M E L I N E Just like it sounds. Timeline.com/doctor Amy D R A M I E to get up to 39. 39 off your Mito Pure Gummies. So that is timeline.com forward/doctor Amy. Now, I don't know about you, but I find it borderline comical when people get into a tizzy when you say anything that goes against what they want to believe or their core beliefs. Oh my goodness. It's as if no one is able to have a difference of opinion. So the reason why we are doing these two podcasts back to back on GLPs is because there really Are. Are two sides of the story. I will tell you, I've never felt more split. More. More just like schizophrenic over a topic than I do around GLPs. Now, I have plenty of podcasts on the benefits of GLPs. I have an entire section in the Thyroid Fix book coming out May 12th. Make sure you get your copy. Right now, I have an entire section on how GLPs can benefit the thyroid, the different things that we're seeing when used properly. And I'm going to continue saying this when used properly because the flip side and what I'm about to go in, in, into. In this episode, the flip side is there's muscle loss, there's hair loss, and there's a negative effect on the thyroid as well. But what does it depend on the dose? The cure versus the poison is all in the dose. So before you start throwing stones and hating on me, because God forbid anyone ever say anything bad about your glp, can you just maybe listen with an open mind? Can you maybe accept the fact that, you know, these men's are kind of new to the market and we're still figuring things out? It's like we're building the plane while it's in the air. And yeah, I mean, technically, a drug should not be built in the air, right? We should know the consequences of any kind of medication. But the bottom line is we can't and we don't. Things have to be out for years, sometimes decades, before we go. Oh, all right. Now we're looking at a. At a more larger population taking this. And now we have some data, now we can start seeing some trends. So I'm going to ask you to just listen with an open mind to this. Now, before we dive in, I do want to share a quick story about my recent experience. Now, again with all of this, I still microdose the GLP people. I am not saying to stop microdosing. I'm not saying to stop your GLPs. I'm just saying be aware and be smart and do not come back and complain to me if you lose your hair and you lose your muscle and you start looking 20 years older because you're taking a GLP the wrong way. I don't want to hear it. Educate yourself and go into it with, yeah, I guess, open eyes, but with your brain activated so that you know what you're doing when you inject yourself with this medication. Okay, so quick story. I overdosed myself on Red Tride. So here's what happened. I normally just micro Dose Turza. And I wanted to try Reda because, you know, all you biohackers out there have been trying it and telling me about it. So I'm like, all right, that's fine. Let me try it. Well, I reconstituted it, and I totally forgot how I reconstituted it. So I had had this vial for probably two months reconstituted, and just decided, like, I'm going to guesstimate my dose. Well, that was a mistake. And these last two weeks that I've had, just pound the point home that this needs to get out. We can't all be on this. Happy, happy. GLPs are amazing and nothing is wrong with them and nobody is doing anything bad. Like, that's ludicrous. That's sticking your head in the sand. That's like saying, like, oh, yeah, those 2020 vaccines, they were fine. Like, we tested them for Dec days before we release them, right? Like, no, we're not going to put our head in the sand. Okay? So my experience the last two weeks really just drove home the point that, yeah, these episodes do have to come out because people need to be doing the right dose or they absolutely will pay the price. And I guarantee you, when I tell you the story, there's going to be some of you that go, oh, that sounds fantastic. I wish that would happen to me. No, no, you don't. So I accidentally overdosed my microdose of red up. And after I got past the first, like, two to three days of crushing fatigue, like, it reminded me of hypothyroid fatigue, where I couldn't even keep my eyes open. They literally wanted to shut during the day. I remember being on a podcast interview and my eyes were just burning like, I'm like, oh, my gosh, I just need to close them. But obviously I couldn't. I was an interview crushing fatigue. And then followed a total and complete lack of appetite that I couldn't even override. So, yes, I was doing three protein shakes a day. And now listen, when Turza has kicked in in the past, or when I go back to my days of in the very, very, very, very beginning. And obviously I have to clarify it because there's some woman on YouTube, of course, that was like, how did you take 5 milligrams? You should know better. I'm like, you listened actually to the video and not react, because everybody likes to react before they listen. It's like the theme of our society. If you actually listened to the video, you would have heard me say that I took that dose. Only way in the beginning, when literally these first came out, they first came out as pens, not as peptides, as Manjaro pens in 5mg. They didn't have the 2.5s back then. So that was the only time I took five. And it was a very similar feeling, but with tursa, it would wear off. This kept going for two weeks. So literally just days ago, I had this big, beautiful steak that we made, and my husband's like, what's wrong? I'm like, I. I just. I literally don't. I don't have an appetite. It's like, what'd you do? And I told them. And, you know, it just. And his frustration, I understand because he's like, you're working so hard to hold on to. To build and hold on to muscle tissue, and if you don't get the protein in, you're going to lose it. And he said, and remember the research that you just did with these meds, with these peptides that we do not 100% know why people are losing 40% lean mass. Now, we know that some lean mass goes whenever you lose weight. We know that. And we know that lean mass can be comprised of water as well as muscle. I say that in this episode as well. But you're gonna lose some muscle as well, independent of what you're eating. So even if you're there saying, well, I make sure that I get in 120 to 150 grams of protein a day. Yeah, so did I, in form of shakes. Even though I couldn't take a freaking bite of food or barely take anything, I still got in my shakes. I'm like, if I can just drink my nutrition for now, maybe this thing will pass in a few days. But it lasted a full two weeks. And then when it wore off, it wore off like it fell off of a cliff. The ravenous hunger that came on was unreal. I never experienced that with tirzabatide. Even when I overdosed myself way back in the beginning, I say overdose because that's what it was. 5 milligrams was way too high. So even back then, when I overdosed on tirzepatide, I still never got the rebound. I never got the 10x rebound on my appetite like I did this time. All of these experiences, I bring them to you just to give you something to think about, not to draw a hard line in the sand. I'm not using fear mongering techniques. You know, there's a lot of people out there that are, for one reason or another, probably Some kind of money trail are using fear mongering to keep you away from GLPs, you know, telling you that they're snake venom or whatever. But then you have the other side, which I mentioned in this episode of the Influencers. Multi level marketing GLPs. What? Where have we gone? I mean, I guess we're not surprised that we have celebrities pushing GLPs, right? Literally pushing and making money off of GLPs. But I don't know, it just makes me shake my head. It really does. So my goal in bringing you all of this information, my anecdotal, experiential and then clinical scientifically back because I've been going down these rabbit holes. I've been in the rabbit hole people. I have been in the rabbit hole of GLPs for years now, learning from the best of the best, studying, researching, paying attention to my patients that are on it, asking questions, taking polls. And I continuously bring you this information because I don't have a hill to die on. On the one hand, I absolutely know the GOPs have been life saving for people like my friend Adrian who was on the show, former Biggest Loser contestant, game changer for her entire life. And then we have people like Kelly Osborne and Sharon Osborne and Demi Moore and all of these people that look like skeletal hell, they look 20 years old. And listen to me, I know you're under a lot of stress. I get it. Like heart goes out to you with Bruce. I get it. But everybody needs to eat a sandwich. Like just stop. Like you, you look bad, but you look bad. And like I know when I start to lose muscle, I freak out. I mean I just, I'll do anything. I doubled up on my creatine. I was like injecting protein into my veins one way or another, doing resistance training, even standing up, like just you know, doing some butt kicks or whatever, activate those muscles. Because I'm so fearful of losing muscle and apparently a lot of these celebrities aren't or they don't know the benefits of the longevity organ, I. E. Our muscles. So my goal is to bring you the up to date latest, whether it's anecdotal or research based information. And that's what I'm doing. So no stoning, no death threats, no hate mail. Take the information like the human that you are and swirl it around in your mind and then decide whether or not this applies to you and what you're going to do about it. Okay, enough of the high horse. Enjoy the episode. We are going to have a real conversation today about GLPs we're not just going to hype them up. We're not just going to talk about their benefits. We've talked about that on other podcasts. Now we're talking about the dark side. Because now that these drugs have been out for years, we are starting to see the side effects and we are starting to actually notate the side effects, not just on an anecdotal level, but in studies. The bottom line is that people are losing weight. But what no one on Instagram is talking about as they're trying to sell you into their GLP1 program for 129amonth. Thank you, Serena Williams. Is that you're not just losing fat, you might be losing muscle. Well, you are, you are losing muscle and you're losing hair. So if you're noticing weakness, fatigue, thinning hair or the deflated look that we're seeing in celebrities left and right, Demi Moore, oh my gosh, she looks like a skeleton now. You're not just imagining it. And before anyone comes for me, this is not anti glp. This is pro you because rapid weight loss without protecting your muscle and your metabolism can actually make you weaker, older looking and you're going to be metabolically worse. You're going to gain the weight back, not because your appetite came back, but because you lost your lean muscle mass that gave you a metabolism in the first place. So we're going to go through some truth bombs today so you can re examine what you're using for weight loss and rethink some things. I'm going to give you some strategies as well. So stay tuned until the end for some tips and tricks on how you can still use your GLP but use it safely and protect your muscle. So truth bond number one, as we know, weight loss is not the same as fat loss. Your body doesn't care what the scale says. It really cares what tissues you're losing. Are you losing fat or are you losing muscle? So we are seeing muscle loss from these drugs and we're not seeing it just because people aren't eating enough protein and aren't lifting heavy. That was the discussion a few years ago that, oh, you know, you have to eat protein, you have to lift heavy, you have to eat protein, you have to lift heavy. But it's not just that. That's not the only answer. We are still seeing muscle loss with GLPs despite eating enough protein and lifting heavy. And we saw this in a couple of trials, a couple of studies. One was called the step trial. You semaglutide it showed 40% of total weight loss was lean mass. Now, lean mass is including muscle, organ tissue, water and bone. Now, we're not seeing bone loss with GLPs, we're not seeing organ loss with GLPs. We are seeing muscle and water loss. But 40%, not all of that 40% is water. Much of that 40% is lean muscle mass. I remember when I first tried out Manjaro, when it first came out, we're talking what, 20, 20, maybe 20, 21, something around there. And I was using the 5 milligram pen. I mean, it just first came out. We did. We didn't have all of these studies. We did not have this kind of information out there. And I remember seeing a press Release stating that 40% of lean muscle mass, it was probably the surmount trial that 30 to 40% of lean muscle mass was related to tirupatide and semaglutide independent of eating enough protein and lifting heavy. Independent. So I started thinking to myself, is it possible that these GLPs have another mechanism where it is eating away our muscle tissue? And I will tell you, shortly after that trial was released, shortly after the data was published, I noticed it in my arms. I noticed that I was losing lean muscle mass. Now, if you've been listening to me for a while, watching me for a while, you know that I lift heavy. I lhs, I really do. And yes, I eat enough protein. Yes. And I still lost lean muscle mass using 5mg of Tide BI weekly. Well, every other week we're seeing it in trials. Now, the Surmount 1 trial used tirzabatide and this showed a 25 to 30% lean mass loss. So right now we have 40% with semaglutide, we have 25 to 30% with tirzepatide. And that's what's clinical oversight. The real world numbers might be way worse. Way worse. This is only in a trial. Now, why does this matter? Because muscle is your metabolic engine. It stabilizes your blood sugar. It's your organ of longevity. It protects your bones, your musculoskeletal system. It's your strength reserve as you age. So as you lose muscle, your metabolism slows down and then you are at a much greater risk of regaining the weight after you stop that glp. And this is why some people regain fat even faster when they stop it. And it's not because of an increase in appetite. It's because they lost muscle. They literally lost muscle. I need to talk to every woman who's been told your Labs are normal. While your body is screaming at you and rebelling against you. Fatigue, brain fog, the weight that will not come off, mood swings, hair loss, feeling dismissed, frustrated and confused. I get it. And that is exactly why I wrote my new book the Thyroid Fix. The no nonsense guide to fix Fatigue, Fogginess and Fat that won't budge. That just says it all and it is now available for pre sale. So I need your help to spread the message. I am giving you an ask as my listener and a promise at the same time. If you pre order the thyroid fix, my promise to you is to continue delivering all kinds of free advice, information, content, education, empowerment. Because that's what I love to do. Whether it's here in the just fix your thyroid Facebook group or I'm on live. I will give you everything I possibly can if you do me one favor which will be a favor for yourself as well and pre order the thyroid fix. Now. This book is not another list of supplements, vague advice. It's not a diet plan. It's not filled with recipes. It is a clear, honest guide. It is the Thyroid Bible. It is the last thyroid book that you will ever need because it teaches you how to read your own labs. No other book has done that. It teaches you what medication and dose you need. No other book has ever done that. It will help you to understand why you are being misdiagnosed, why you're being under treated and why you can't talk about hormones, weight loss or menopause without talking about the thyroid. I called it Thyroid Bible because like I said, this is going to be the thyroid book of the next few decades. When you pre order you're not just supporting me, you're telling the publisher. This message matters and it needs to get out to the world and it needs to get into the hands of women who have been ignored for far too long. So will you go to thyroid fixbook.com and pre order a copy of yours today? It'll be shipped to you on May 12th and you will get free entry to our all day live event where I will be there answering your questions live, teaching live and bringing in amazing guests for you to also connect with and ask your questions too. So thyroid fixbook.com pre order yours today. So this is a problem because if we don't protect our lean muscle tissue we will break down and we will notice an increase of all cause mortality as our muscle breaks down. Truth bomb number two rapid weight loss is a muscle loss machine. GLP1s yes they suppress appetite so they cause us to reduce our caloric intake. Sometimes we do have inadequate protein intake. I get it. If you are killing your desire to eat altogether, there's no way you're getting in the calories, the nutrients, and the protein. So your body literally interprets this as scarcity and it will break down muscle for energy. Now, I know. And. And please do not lie to yourself. Do not lie to yourself. I know firsthand that even with a micro dose, my appetite can sometimes be suddenly crushed for five to seven days. And no matter how hard I try, no matter how many protein shakes I drink in a day, I cannot get the calories and the protein in that I should be getting in to protect my muscle. It's like a struggle. It's like you're overcoming this deep desire to not eat. It's almost like a nausea. You can't even look at food. You can't even think about it. You can't do a third protein shake in a day because that's all you can get down. If you are honest with yourself and really tune into your body. You know, if you take a little bit too much of a glp, you completely lose your appetite. I even did that this week with R A True Tide. I took a little too much and it destroyed me for a good week. I struggled to eat enough. I was fatigued, I was nauseous. I wish I could just pull that drug out of my system, it was so bad. And yes, I literally lost muscle this week because I couldn't put down enough food. My body was breaking down. So not only is the GLP one directly affecting your muscles and breaking them down, your body's breaking down your muscle tissue for energy in general, rapid weight loss. Research shows that 20 to 40% of weight loss can be lean tissue without resistance training, inadequate protein. So even if you were on a hardcore diet, you would lose that. But when you restrict your calories and you just simply cannot eat, you are going to break down muscle tissue. Now, older adults and women over 40 are at an even higher risk, because already after 40, you're losing muscle mass. I'm hoping that you are addressing your low testosterone, but you are losing muscle mass. Hormonal changes, there's a reduced anabolic signaling or building of muscle tissue. You have thyroid decline, you have lower testosterone, you have lower estradiol. All of this is affecting our fat. You can go back and listen to the podcast episode I Did. It is episode 615, why women over 40 can't lose weight. Well, that podcast episode is talking about if you are over 40, your estrogen decreases, your thyroid decreases, your testosterone decreases. So therefore you gain more fat and you can't lose the weight. Well, if you lose muscle on top of that, you're also going to damage your metabolism, and you may or may not come back from it. Muscle is your metabolic currency. It's like a money in the bank for a metabolism. So even when your thyroid declines, if you have enough muscle on your body, it can save you until you can get your thyroid optimized. But if your thyroid is low and your testosterone's low and your estrogen's low, and you're taking a GLP one, you are going to age so quickly and you are going to lose your muscle, and inevitably you are going to break your metabolism, you're going to burn fewer calories at rest, you're going to increase your insulin resistance, you're going to lose bone, you're going to lose mobility, you're going to lose independence as you're losing your muscle. You lose enough muscle and you enter a state called sarcopenia. And that accelerates aging like crazy. Don't do it. Truth bomb number four, why people look older after rapid weight loss. I eat Demi Moore. Because it's not just fat loss. You're actually losing the subcutaneous fat Ozempic phase Manjaro face. You're losing your skin laxity, you're reducing your collagen support, and you have hormonal changes. So ozempic face is real, and this is why people are looking 20 years older than they actually are. Yes, that is kind of tied into the muscle loss as well. So now we're moving on to hair loss. I've been getting this question a lot lately from patients noticing hair loss when they are on even a micro dose of the glp. So this is being reported clinically, but we're not seeing any studies showing that the drug itself is like toxic to your hair. It's basically the environment that it creates. So why is hair loss happening with GLPs? Well, hair follicles are incredibly sensitive. Incredibly sensitive. Have you ever been stressed? Did you have Covid? Did you notice your hair respond to that? Our hair follicles are very sensitive to our environment, so. So if we lose weight rapidly, if we are deficient in our nutrients, if we restrict our calories, if we are under stress or our body is under stress, maybe because of hormonal shifts or because of thyroid changes, or because we are over restricting, we're undereating, maybe even over exercising as well, but definitely undereating. Taking a glp, not getting in enough protein, not getting in enough calories, not lifting heavy enough, not addressing our low testosterone, not addressing our low thyroid function. That is a stressor on the body, hormonal shifts, aging, stressor on the body, your hair will respond to it. So all of those triggers will actually initiate something called telogen effluvium. This is a shedding phase of the hair. It usually shows up two to four months after the trigger. I'm going to say that again. It shows up when you lose your hair, when you shed your hair, when you notice additional hair loss two to four months after the trigger. I always say this in every hair loss episode. I'm done. I say go back two to four months. This is not something that happened yesterday. This is not caused by something you did last week. This is two to four months. When Covid hit, we saw hair loss about the 90 day mark. 90 days after someone had Covid, we saw hair shedding, hair breaking, hair loss, two to four months. So when you start in glp, it might be two to four months until you notice that you are shedding significantly more hair. So the known contributing factors on GLP1s, we know that there's reduced protein intake. We're seeing more and more low iron and low ferritin in people on GLP1s. And we know that ferritin is directly correlated with hair. If you have low ferritin, we can tie that to hair loss. It's one of many factors because hair loss is multifactorial. But we are seeing lower iron levels and lower ferritin levels in the GLP population. Zinc deficiency, biotin deficiency, we're seeing thyroid dysfunction. And in part two, talking about the Dirk side of glps, I'm going to be talking about what we're seeing on thyroid labs and with thyroid function directly correlated to GLPs, and then we're seeing that sudden fat loss from use of a glp, altering the hormonal balance. When your body thinks survival is the priority, hair growth is not on the to do list. It's just not. Your body will always shuttle its energy to survival first and whatever that looks like. If you're under a boatload of stress, your body knows, my gosh, we can't keep pumping out cortisol, we can't deplete our hormones. It doesn't care if you have good hair, it just wants to keep you alive. And as we'll see in part two, as we are using a GLP and we are losing weight, this unfortunately increases reverse t3 and hinders t4, t3 conversion, which that increased. Reverse t3 can also come back. And again, it's the survival mechanism. It tells our body, you don't need to grow hair right now. Like, that's legit. Not important. What you need to do is survive. Survive. So many users of GLPs are not getting enough protein and micronutrients and calories and electrolytes. We know that that's going to lead to fatigue, weakness, hair thinning, mood issues, muscle wasting, all of that. This drug, GLPs, are a tool. They are not magic Medic. These medications, they absolutely have helped people. I do not discount that whatsoever. And if you are like my guest Adrian Gledhill that was on the Biggest Loser, you can go back and watch her video as well. We can link to it and her podcast episode. She legitimately struggled her entire life with weight. She fell into the category of someone who is GLP deficient. In her case, I bet if you asked her, she would say, I'll take the little bit of hair loss to finally have some control over my body. This is a give and take. There are pros and cons. Just like anything, we have to weigh them out to know whether or not a certain drug or a certain protocol is right for us. So Adrian, I know is doing everything she possibly can to maintain her muscle and maintain her hair. But the bottom line is, for her, that's not as important as control over her weight, which will rebound very, very quickly when not on a glp, that is a smaller subset of the population. If we're honest, people are taking this just to shed an extra 5 or 10 pounds, maybe 15 pounds, and they're taking this as really a quick fix. Instead of looking at their thyroid, instead of looking at their hormonal profile, they're just throwing on a glp. Well, half the time, it's not going to work. If your thyroid's in the toilet. We have to shift our priorities. You have to take in more protein. If you are on a glp, you better be doing five days a week of weight training or resistance training. You have to have all of the micronutrient support. Iron, zinc, B vitamins, vitamin D, magnesium, essential fatty acids, essential aminos. You have to monitor your thyroid because low calories plus weight loss can worsen thyroid function and increase reverse T3. We have to do all these things and then we have to make the educated decision as to whether or not the GLP medication that we choose. I can't even say GLP1 anymore. Now we have 1, 2, and 3. The GLT medication that we use is the juice worth the squeeze. What are we going for here? Are you truly obese? Do you have an elevated A1C? Do you gain weight even after your thyroid is optimized, your hormones are optimized, your insulin is optimized, and maybe you just fall into that small subset of GLP1 deficient people. Okay, sure. But if you're not in those categories that I just talked about and you are using GLP as a hack to maintain body weight or keep your body weight low, I really want you to think about it. Now here are my tips and tricks. If you want to still use your glp, you're like, no, don't take this out of my hands. Okay, so what I want you to do is use the lowest dose possible, a true micro do. And I'm not talking about instead of 5 milligrams using 2.5, I want you to find your lowest dose possible of whatever GLP you were choosing. Yes, the dosing is different for seglutide, tiride, retatrutide, it's different for all of them. Find your absolute bottom of the barrel dose and try to use that every other week. If you've hit your goal weight, or even if you're, let's say, ten pounds away from your goal weight, I still want you to use it every other week. It's still going to help with inflammation, but it's going to be at a micro, micro, microdose. Then on top of that, and now all of this is assuming that the landscape is taken care of, that you've already tested and addressed low thyroid function, that your free T3 and reverse T3 are optimal, that you are taking bioidentical hormone replacement. If you are over the age of 40, whether it's progesterone, estrad, testosterone, you're testing and addressing your hormones, then and only then can you add on glp. You have to do all of that first. So I'm going to assume that you've done all of that. Now you're adding on a glp. So now let's break down the right way. So micro, micro, micro do weekly or every other week? Every other week, preferably. And then I want you to add in T too, because this is going to increase your basal metabolic rate. So when we increase your metabolism, when we increase that fat burning, then that's the ultimate goal. Right? Then we don't have to rely on controlling our appetite to reduce the amount of calories that we're taking in, which is going to make muscle loss and hair loss that much worse. Now we can have that metabolic activation, the increase of thermogenesis, the increase of fat burning, in addition to the benefits of micro, micro microdosing a GLP. So we're going to combine these two together. So we're going to add in T2, which is going to reduce inflammation, it's going to reduce your reverse T3, it's going to help with T4 to T3 conversion, it's going to reduce oxidative stress, it's going to increase your baseline metabolism, the amount of calories that you are burning at rest, which, by the way, your baseline metabolism, your BMR, will drop when you're on a glp, when you're not eating enough calories. Our bodies will adjust our metabolism based on how many calories we're taking in. So if you're down to a thousand calories because you just can't eat enough in a day because of the glp, then your body will downregulate its burning to only burn a thousand calories. T2 comes in and it's going to increase that back up so you can increase your eating because you're decreasing your GLP1 dose to a true microdose and maybe you're doing it every other week or once a month. This is where the T2 comes in and bridges that gap and keeps your metabolism up, that metabolism that you already destroyed by taking a GLP and losing muscle. So you're going to add in T2. Now, if you do need a little bit of help in the appetite department, this is where you're going to add in Suppressa. So I have T2 and suppressa in my metabolism fixer. Suppressa is a saffron extract. It reduces Appetite by about 69%. So when you add in Suppressa, and this is what I do with patients that are coming off a GLP or trying to space it out more, Suppressa is still controlling that food noise so they don't have to rely on a GLP to control the food noise. They can add in Suppressa, get the benefits of T2 and protect their precious earned muscle and their beautiful hair. Because once you hit your hair, that takes six months to a year to come back. Takes a long time to come back from that hair loss. Just remember that losing weight, but losing muscle metabolism, hair and strength along the way is not the win that you were promised with GLPs. It's not. And in part two, we're going to be going deeper what these drugs might be doing to your thyroid, how they interact with your hormones, and why some women feel amazing and others feel terrible. The information shared on the Thyroid Fixer Podcast is intended solely for informational and educational purposes. 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