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It's brand freaking new. And not that we need the FDA approval, because we don't. However, common sense gonna roll back to 2020 and 2021 right now. Common sense says when something has just been developed and not thoroughly tested on the human population, maybe we should avoid it. Maybe we should just think twice about it. Maybe we don't want to be the first. I just want to say thank you. The fact that you're here means that you have trusted me with something so valuable these days, your time. And I do not take that lightly at all. So if you're listening because you're exhausted, you're gaining weight for no reason, losing your hair, getting really frustrated, or you've been told that everything looks normal when you know deep down, something isn't right, I want you to know that I see you. I've been where you are. And that's exactly why I created this podcast. My mission is super simple, to give you the information, the hope, and the tools that I wish someone had given me years ago. 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You know, I feel like anytime I do a podcast on glps, I always have to preface this with I am not anti glp, because, my gosh, the addiction is real out there, right? I guess the benefits are real and the addiction is real as well. But as I always do, I continuously, as we all should be doing, I continuously look at both sides. I look at the pros, I look at the cons, I look at the studies, I look at the anecdotal evidence that is coming out, and I look at our patients. I look at how I Respond. I listen to other stories of people. I dissect it. So if you hear a horror story, you step back and you go, oh, well, were they taking, you know, like 10 or 15 milligrams? And that's why they got that side effect of gastroparesis or what's the deal? So you have to look at everything. You have to break it down and look at it through a very, very clear lens. But you also can't. We can't put our head in the sand and pretend like there might not be some things popping up that we just don't. So here's the reality. GLPs haven't been out that long. So as we know with any drug. I paused there because I was thinking back to 2020. As we know, with any drug, there can be side effects that don't show up for a few years, that only show up because of the accumulation of years of use versus using something for a short period of time. So the reality is, is that we really don't know. What I wanted to do today and what kind of popped into my head was I was thinking about this show, and I don't know if all of you have seen this or not, but it's on fx. And FX is like a little bit of a wild channel, so they have some really crazy shows out there. But it's called the Beauty. It's very, very good, by the way, Ashton Kutcher, a couple other people that you'll recognize. But it's called the Beauty. And I watched it, obviously for entertainment, but then when I got to the end, it made me pause and think about the parallels of GLPs right now. So in a nutshell, and I won't give it away because you'll have to watch the show, but in a nutshell, this billionaire played by Ashton Kutcher, develops a shot, a shot, an injection that makes everyone beautiful. So no matter what health condition, what size they are, what their face looks like, what their body looks like, you take this shot and you immediately turn into this beautiful model. But there's a catch. It turns out that the shot is a little bit unstable in what it does to your DNA, and you spontaneously explode from overheating, usually within two to three years of the shot. And then it turns out as the shot was out longer and longer, there were various mutations. Like it would turn a 40 year old into a 9 year old, or it would turn people into a skinless monster. You know, some pretty wild side effects. But they pushed it. They pushed it for the money. He wanted that shot out. He wanted to control it. He took over social media, he took over the news stations, he made a commercial so that every single person, including teenagers and college students looking at their phone, would be pulled in. They want this beauty shot for money, for money, for money, for money. And again, I won't tell you how the show ends. I won't tell you how the show ends. Hopefully there's a season two, but it made me step back and think about the GLPs, the shot, and what are the side effects that we don't know yet. What are the side effects that are going to come up three to four years down the road? There's things that we just don't know. And there are times where, you know, it is big Pharma, it is Lily, it is Novo. What are we not being told? What are we not being told? So again, I don't want to talk about cons or scare the bejesus out of anyone until we talk about the pros. So what are we seeing with the pros? And I'll recap this. If you haven't listened to any of my other GLP episodes, I will recap this once again. What do we know right now? Okay, so if you are obese and you are carrying around excess body fat that really is detrimental to your health, so if you are one that qualifies for the use of a GLP because you are a type 2 diabetic and your A1C is well above a 5.6, and you are carrying around excess adipose tissue, I. E. Fat, then yes, GLPs are changing lives because your risk of all cause mortality, basically everything that can possibly kill you is, increases significantly when you carry around excess body fat. It creates inflammation and increases your risk of cardiovascular disease. It feeds cancer because cancer feeds on sugar. So walking around with high glucose, high A1C, high insulin, you're feeding cancer cells, you're risking neuropathy, you're risking the loss of eyesight, of fingers, of toes, of limbs. I mean, the list goes on and on and on. As it cascades, as obesity continues and that inflammation continues in the body, a host of various conditions that can kill you start to appear. Alzheimer's has been called type 3 diabetes for years now because we know the association between the plaque formation of the brain and the inflammation and high blood sugar, high glucose. So now we have a shot that comes along and really, I mean, just kicks all of the other diabetic medications to the carb because it works and it works fast. And people Are losing weight for the first time in their life when they haven't been able to before. People who have had gastric bypass surgeries are that really, I mean, come on. Sometimes works, sometimes doesn't. Sometimes just leaves you miserable. Are now having their gastric bypasses reversed because they can control their weight and lose the weight. With a glp, we're seeing improvements in fatty liver. We're seeing improvements in lifid panels. As I've said before on a previous episode and as I state in the Thyroid Fix, if you haven't picked up the book yet, I have a special chapter on GLPs. We're seeing some individuals needing less and less thyroid medication. So that's fantastic. And again, not that the gold star is to be on the lowest dose of thyroid medication. That's not the point. But if you can reduce it, then okay, then that works because you're reducing the inflammation in your body. So there are pros that we are seeing. Oh, an additional pro. Mood. A lot of people are experiencing an improvement in their mood when the GLP is used appropriately for you. When it's used at a dose that is appropriate for you, that's usually a micro dose. It's usually not a macro dose or a standard dose that we use for a type 2 diabetic. But when used appropriately, we are seeing these things. Now, the other side, the reality. Some women are losing hair, many people are losing muscle, some are losing facial fat and looking older. Again, I have said this in another video. We can even link it below. I have a multitude of videos on GLPs, a multitude of episodes on GLPs. We have the dark side of GLPs. We have the pros of GLPs. We have my interview with Tina Moore where we talk about microdosing GLPs. We talk about this a lot because listen, it's a hot topic. And again, what did I say in the very beginning? This is new. This is still new. I don't care. The GLPs have been out for four or five years. It's still new. It's a new drug. It is a new class of drugs. Red. A true type. People are buying it left and right from research facilities, research peptide websites. They're buying it from compounding pharmacies that really shouldn't be compounding it because it's not FDA approved yet. It's brand freaking new. And not that we need the FDA approval, because we don't. However, common sense gonna roll back to 2020 and 2021. Right now, common sense says when something has just been developed and not thoroughly tested on the human population, maybe we should avoid it. Maybe we should just think twice about it. Maybe we don't want to be the first. Don't want to be the first to get that beauty shot right and then spontaneously explode. So what do we do? Well, number one, I know, I mean, listen, you can go on Instagram, you can go on Tik Tok right now and see picture after picture of these lean bodies saying, I take red. A true tide. I shared with you. The girl that washed my hair at the salon told me that she knows that the research only website that she got her reta from is valid because you know the Tik Tok influencer that was promoting it is skinny. You don't know what's in that. You don't know. So, number one, I would say, I'm sorry, go ahead and burn me at the stake like a Salem witch. I'm gonna say to avoid Retta, because you just don't really know yet, do you? Okay, at least Tirza and Sema have been out for a few years. So we have a lot more data on those two drugs. If you want to use Reda, go ahead, use it at your own pace, at your own risk, whatever, and just realize it's a little bit newer. But Sema and Terza being out for the four or five, however many years they have been out, we at least have a lot more data on that. Because since it is FDA approved and it is in the form of a pharmaceutical, which Retta will soon be. Yes, we have more people using it. We just do. I mean, those are just the common sense stats. If a person can't get it from their doctor, can't really get it legally from a combining pharmacy, and they have to order it from the black market, there's going to be less people using black market than there is using real approved compounded medication. So we have more data. We have more data on SEM and Terza. Not that we have enough, because we don't. And that's just the reality. And really the point of this is to say when we. And I'm putting myself into this category, I'm right there with you. When we use GLPs, we have to realize that we're taking a risk. We just are. Now you could sit back and go, well, Dr. Amy, isn't it risky to take thyroid medication or hormones? Not really. They've been around for like over a century or at least for 70 years. So, you know, NDTS were 1800s T3 was approved in the 60s, 50s, 60s, something like that. 40, 50s, 60s. And then T4 was approved. 70s, 80s. I'd have to look at my stats. I wasn't really prepared with when Thyroid medic. I don't have it memorized when it was released and approved by the fda. However, they've been out for a really long time. This is new, These are new. This is a new class of drugs. Miraculous. Yeah, possibly could be our next answer and maybe 5, 10 years from now we will see that there's like a.05% of the population that has the side effects and 99.5% experience fantastic life saving, life changing, life altering, mind blowing results. Or we're going to hear in five to 10 years, oops, sorry. Turns out that these GLPs increase your risk of cancer instead of decrease. It turns out that you might spontaneously combust. No, I'm just kidding. We might. And that's just the reality. I think again, we would literally be sticking our head in the sand if we said to ourselves, there's no problem here. Don't you know that Eli Lilly and Pfizer and Novo have our best interests at heart? They would never put a drug out that could harm the human population. I can't even say that with a straight face. So what's the point, Dr. Amy, what's the point? My point in coming on here is to just help you think. It's just for you to step back and evaluate. And I will tell you straight up, even with this thought, even with the full acknowledgement that five years from now we might find something, something that we went, ah, didn't see that coming. I'm still going to use it, still going to use my tirzepatite at a microdose because of the beneficial side effects that I have experienced thus far. But I'm going to do so with open eyes and I'm going to pay attention to every minuscule thing that my body does as I use the GLPs. And I'm going to make sure, as I have been for decades, that I'm taking care of myself and that my body doesn't rely on a glp. I'm going to do things that actually do increase my metabolism, like I add in T2 because GLPs don't increase your metabolism. I had another podcast on that. I'm going to add in T2 to make sure that my metabolism is running where the micro dose of GLP keeps my inflammation down and helps to keep naturally my insulin and glucose down. Although I Do that mainly through diet, exercise, sun, sun exposure, grounding, stress reduction. All of that helps your glucose and your A1C naturally. Remember back in the day when we had to do it naturally? I still add in berberine because that's amazing for anti cancer, it's amazing for prevention of Alzheimer's. So I still do the other things. I don't throw the baby out with the bath water and say all I'm gonna do is GLP and call it a day. I'm still doing all the other things to support my body and support my metabolism and I'm going into or continuing my GLP use with eyes wide open. Now, the other factor here that I bring up every single time I talk about GLPs is cost. Well, cost. There's two things. There's cost and there's the are they going to be accessible? Because as we know and every single time we talk about GLPs, we have to mention this. As we know, Lily Novo, they're trying their hardest to make sure that you have to get a prescription from them that those dollars aren't being shuttled to the local compounding pharmacy that makes sure Zepatide, they want it all. And that level of greed makes me scratch my head as to why. Why do you want us using your drug? What you got in it, what else you got in it? We already tried population control one time a couple years ago. Is this another attempt? Why can't we use compounding? Lily? Hmm. Another pause and think moment. Just food for thought. Just food for thought. This is not a podcast where I'm standing on a pedestal. I'm not trying to move you one way or another. This is actually one episode where I'm just putting out my thoughts and I'm kind of hashing this out with you. If we were sitting here having coffee, we'd have a back and forth conversation. I would listen to your opinion. I would listen to the thoughts that you have that pop into your your head through a conversation. And we would have an educated, fun discussion about it with neither one of us dying on a hill. I don't have a hill to die on with GLPs. I really don't. As I've said many, many, many times, I believe it's the wildest JY and Hyde drug that has ever hit the market because we literally don't know whether it's good or bad. We're experiencing the good right now. We're seeing some bad, we're experiencing some good. A lot of it is dependent on the dose that you use and whether or not you change your lifestyle habits while you're using it and after and during. Yes, it will. While you're using it. I want to give you just food for thought. So you can take this and even though you and I can't have a conversation, which I would love to, you can take this and have a conversation with your girlfriend that's using a GLP too and ask her about the side effects. Ask if she's experienced anything weird. Has she lost her hair? Has she lost her facial fat? Has she lost any muscle? Does she think? And then do a self inventory yourself. We don't know. One other thing I've been hesitating this entire episode to say, but I'm just going to say it talking to a friend of mine. She mentioned this because she sees it in her chiropractic practice. And ironically, many of you know that I had cancer last year. Uterine cancer, she says. I have seen now six cases of uterine cancer in the last year on women using GLPs. And yes, I was using a GLP prior to my uterine cancer diagnosis. I did another podcast a while ago. A while ago. Last year. Last year. Because it's been a year since my diagnosis and since my hysterectomy. I did a podcast last year on I think I know what caused my cancer. That's actually the title of it. You can go look for it. I don't know what number it was. And I mentioned that I believed because of the fact that uterine cancer is an older person's diagnosis, meaning we normally see it in women in their 70s and 80s, not in their 40s and 50s like we're seeing right now. And even my oncologist said, you know, this is a cancer that we normally don't see in someone your age, especially someone that's healthy. So what is it? Is it that I had Covid? Is it that I had a man made virus like many of us did, and that changed my DNA and tweaked my immune system so that my surveillance system was down and didn't detect those cancer cells like it normally would? Or was it the microdosing of the glp? Or was it the macro dosing of the GLP that I did in the very, very, very, very beginning when Manjaro came out and I already shared my horror story with that of absolutely losing muscle, losing facial fat, all the things, the nausea, the fatigue, dose dependent, dose dependent. I don't know. I don't know. So take all of this information, swirl it around in Your mind. Sorry to just confuse you. I know you just listened to this podcast hoping and praying that I was going to be screaming from the rooftops how amazing GLP are. Yeah, we prescribe them in our program because there's positives. We're not not going to prescribe them because we don't know yet. This is an individual decision. It's a decision to be made with your practitioner, with your prescriber. It's a collaborative decision. We respect everyone's decision. If somebody says, I don't want to use it, I'm like, okay, then don't use it. Here, use metabolism fixer instead. If you got the food noise, it's a natural way to control your appetite. And oh, by the way, the T2 and it's going to boost your metabolism, which GOPs don't do. We'll use that instead. We'll use black cumin seed oil for inflammation. We use LDN for inflammation. There are other things that we can do. If you're not comfortable using a glp, I might move that way entirely eventually. Here. I don't know. I'll keep you updated. I'll always be honest with you. You know that. You know I won't you because I am anti bullshit, especially on social media. There's too much of that out there. Do you agree? Yeah. I'm not going to push you into a program. I'm not going to try to sell you anything that you're not comfortable with. I'm going to give you all the data, the information, the anecdotal evidence that I possibly can. And ultimately I'm going to let you decide because you're a smart human being. That's why you're listening to the show, you're gathering information, you're trying to make decisions. But go ahead and just go watch fx, go watch the beauty. It's entertaining. If you love series, you know, you know I love. I call it my Netflix time and my Netflix snack. That's how I down regulate late at the end of the day, it turns off my brain because I focus on a show. My brain's always going type A's, ADD entrepreneurs just always driven people. You're always going, you know, you know who you are. Your brain's always going. So that's why I watch series to shut it down at the end of the day. So, you know, binge it. Go ahead and binge it. And then I want you to DM me on Facebook or Instagram or join my just fixture thyroid Facebook group, which is amazing freaking group anyways and post in there. Be like Dr. Amy. I watched the Beauty Holy. So entertaining. And I saw the parallels. I see. I said, yeah, okay, it's making sense now. I see what you're saying. I see what you're saying. Oh, my goodness. I love you all. Thanks for watching. Let me know what you think. Food for thought, right? Let me know what you think. We'll see you next time. Share the episode too, because you know, your girlfriend or your neighbors taking a gop.
Host: Dr. Amie Hornaman
Date: July 24, 2026
In this episode, Dr. Amie Hornaman explores the parallels between GLP-1 medications and societal desires for quick fixes, using the FX show “The Beauty” as a lens. She addresses both the significant benefits and potential long-term dangers of GLP-1s, emphasizes the novelty of these drugs, and advocates for caution, critical thinking, and individualized decision-making.
02:00)"It's brand freaking new... when something has just been developed and not thoroughly tested on the human population, maybe we should avoid it. Maybe we should just think twice about it. Maybe we don't want to be the first." (00:00)
04:00)"It made me pause and think about the parallels of GLPs right now. What are the side effects that we don't know yet? ...There are things that we just don't know." (07:50)
10:20)“GLPs are changing lives because your risk of all cause mortality... increases significantly when you carry around excess body fat.” (11:40)
16:50)“Common sense says when something has just been developed and not thoroughly tested on the human population, maybe we should avoid it. Maybe we should just think twice about it.” (19:20)
25:10)“I'm still going to use my tirzepatide at a microdose because of the beneficial side effects... But I'm going to do so with open eyes and I'm going to pay attention to every minuscule thing that my body does.” (28:00)
32:40)"That level of greed makes me scratch my head... Why do you want us using your drug? What you got in it, what else you got in it?" (34:00)
36:40)“I have seen now six cases of uterine cancer in the last year on women using GLPs. And yes, I was using a GLP prior to my uterine cancer diagnosis.” (38:00)
43:50)“There are other things that we can do if you're not comfortable using a GLP... I'll always be honest with you. You know that I am anti-bullshit, especially on social media. There's too much of that out there.” (44:40)
On the social phenomenon of “miracle” fixes:
“We all want the beauty shot... But it’s a little too close for comfort, how fast things can go wrong when we don’t know the long-term side effects.” (08:50)
On the current GLP-1 landscape:
“It is the wildest Jekyll and Hyde drug that has ever hit the market because we literally don’t know whether it’s good or bad.” (47:15)
On personal agency and skepticism:
“Ultimately, I’m going to let you decide because you’re a smart human being. That’s why you’re listening to the show, you’re gathering information, you’re trying to make decisions.” (48:10)
Dr. Amie’s tone throughout is candid, practical, and often humorous, encouraging listeners to remain skeptical, informed, and proactive. She’s not anti-GLP-1, but she wants her audience to “go in with eyes wide open”—questioning hype, knowing both risks and benefits, and always striving for true health beyond the allure of miracle injections.
“Food for thought, right? Let me know what you think. We’ll see you next time. Share the episode too, because you know, your girlfriend or your neighbor’s taking a GLP.” (End)