The Tonight Show Starring Jimmy Fallon
Episode: Trump Launches Prescription Drug Website | Halle Berry, Dylan O'Brien, Josh Safdie
Date: February 6, 2026
Episode Overview
This episode of The Tonight Show packs in high-energy comedy, timely pop culture riffs, and star-studded interviews. Jimmy Fallon opens with topical humor centered around Donald Trump’s new “TrumpRx” prescription drug website, segues into playful music and Olympics jokes, then features extended and upbeat conversations with Halle Berry, Dylan O’Brien, and director Josh Safdie. Highlights include Halle Berry clarifying rumors about her relationship, O’Brien’s stories from set with Rachel McAdams, and Safdie’s deep-dive into his Oscar-nominated film Marty Supreme.
Monologue & Topical Jokes
Trump’s Prescription Drug Website
- [01:13] Jimmy sets the tone with jokes about President Trump’s new online pharmacy:
- “Trump RX is the only pharmacy where the dosage instructions are: ‘A lot of people are saying two.’”
— Jimmy Fallon, [01:33]
- “Trump RX is the only pharmacy where the dosage instructions are: ‘A lot of people are saying two.’”
- Pokes fun at “buying Xanax from the reason you need Xanax.”
Olympics and Winter Jokes
- [01:57] Jimmy and Josh Safdie riff about the Winter Olympics starting the following night:
- Jokes about speedskater Erin Jackson and bobsledder Frank Del Duca as flag bearers.
- On a norovirus outbreak for Finland’s women’s hockey team: “Everyone in doubles luge is like, if that’s true, then we’re screwed.”
— Jimmy Fallon, [02:13]
Valentine’s Song Sketch
- [02:51–05:17] R&B duo Dirk and Sammy perform a comedic ballad about getting “freaky in the winter,” which devolves into a routine about stripping off endless winter clothing:
- “First I’mma take my coat off, shake off all the snow…then I’mma take my scarf off, throw it on the floor…”
— Dirk & Sammy, [03:14-03:36] - Jimmy interrupts, overwhelmed by the layers: “It’s just a lot of layers of clothing you got there.”
— Jimmy Fallon, [03:52]
- “First I’mma take my coat off, shake off all the snow…then I’mma take my scarf off, throw it on the floor…”
Pop Culture Bits
- [05:20] Jokes on Apple’s “F1” sequel getting a confusing name:
- “We’re proud to bring you the sequel F1.2—No, that’s confusing…the sequel F. F1. No, F me. No, FU. No…just call it Brad Pitt Car Movie.”
— Movie Teaser Voice & Jimmy Fallon, [05:33–05:56]
- “We’re proud to bring you the sequel F1.2—No, that’s confusing…the sequel F. F1. No, F me. No, FU. No…just call it Brad Pitt Car Movie.”
- [06:04] Disney’s new “Haunted Mansion” wedding event quip: “Sounds like fun till your wedding night when you hear your wife singing ‘It’s a Small World.’”
Super Bowl 60 – Tonight Show Superlatives
[07:40–09:30]
Jimmy and guests poke fun at Super Bowl players with imaginary “Yearbook Superlatives”:
- Patriots’ Drake May: “Most likely to stand outside Hollister with his shirt off.”
— Jimmy Fallon - Seahawks’ Sam Darnold: “Most likely to bleed milk.”
- Seahawks’ Cooper Kupp: “Ramen noodle-iest.”
- (And others; this recurring Tonight Show bit is rapid-fire and playful.)
Celebrity Interviews
Halle Berry
[09:49–17:11]
Relationship Rumor Clarification
- Halle sets the record straight on rumors about rejecting a marriage proposal from Van Hunt:
- “There’s some confusion that he asked to marry me and I said no…that’s not the case. I did not say no. We just don’t have a date. But, of course, I said yes.”
— Halle Berry, [11:01]
- “There’s some confusion that he asked to marry me and I said no…that’s not the case. I did not say no. We just don’t have a date. But, of course, I said yes.”
On the Olympics and Super Bowl
- Shares love for the Olympics and past as an aspiring gymnast.
- Will watch the Super Bowl “mainly for Bad Bunny.”
- “He’s gonna crush it. I love that dude.”
— Halle Berry & Jimmy Fallon, [12:36–12:44]
- “He’s gonna crush it. I love that dude.”
Adventures with Her Son
- Discusses outdoor Utah/Grand Canyon trip with her 12-year-old son, facing her fear of heights on a swinging bridge:
- “We climbed the Hoodoo Canyon...like 500ft up in the air. It was crazy...I had to face my fears.”
— Halle Berry, [13:26–13:45] - “Van sat this one out. He was like, y’all are crazy, I’m not doing that.”
— Halle Berry, [14:13]
- “We climbed the Hoodoo Canyon...like 500ft up in the air. It was crazy...I had to face my fears.”
“Crime 101” Movie
- Talks about her new film, Crime 101, calling it:
- “A throwback to those great movies of the past. Like Collateral, Heat, The Thief… Propulsive, they have action, they have great characters. L.A.—it’s a love letter to L.A.”
— Halle Berry, [15:10–15:22]
- “A throwback to those great movies of the past. Like Collateral, Heat, The Thief… Propulsive, they have action, they have great characters. L.A.—it’s a love letter to L.A.”
- On the ending: “When I was reading the script, I was like, this is so good, but this better end right…all I have to say is, the ending is money. It is so satisfying.”
— Halle Berry, [15:41–16:23]
Memorable Moment
- Asks Jimmy to question Chris Hemsworth (tomorrow’s guest): “Ask him to tell you why I—as Storm—will not be in Doomsday. He knows the answer.”
— Halle Berry, [16:45–17:01]
Dylan O’Brien
[17:47–25:49]
SNL Movie & Dan Aykroyd
- Praises from Jimmy: “You were great as Dan Aykroyd in the SNL Movie.”
— Jimmy Fallon, [18:10] - Shares childhood photo of himself as a Blues Brother at a talent show—“I literally was him.”
— Dylan O’Brien, [18:42]
“Twinless” and Producing
- Talks about producing and starring in Twinless (now on Hulu), which took four years to make.
- James Sweeney wrote and directed; O’Brien played a twin, but never had to act opposite himself in the same shot.
“Send Help” Movie
-
Stars alongside Rachel McAdams in the box-office hit Send Help.
-
On Rachel:
- “She’s the most grounded, like, a human can get, especially considering she’s a multi-generational icon… she doesn’t… contextualize them with a name-drop or anything…”
— Dylan O’Brien, [21:10] - Tells a funny story about Rachel referring to Mean Girls and The Notebook without being aware of their icon status:
- “Are you talking about Mean Girls?” —Dylan O’Brien, [22:20]
- “She’s the most grounded, like, a human can get, especially considering she’s a multi-generational icon… she doesn’t… contextualize them with a name-drop or anything…”
-
On his physique for Send Help:
- Teases of a viral TikTok showing his outdoor workouts in Sydney.
- “That’s the two pull-up workout. I could put it on a little—check out my Substack if you want my routine.”
— Dylan O’Brien, [24:28–24:33]
-
Plot summary from Dylan:
- “Rachel McAdams plays a character named Linda Little, who is underappreciated… I take my dad’s place as boss, I’m not a nice guy…we get in a plane crash…she’s way more equipped to survive than I am, so I become kind of her captive.”
— Dylan O’Brien, [24:40–25:32]
- “Rachel McAdams plays a character named Linda Little, who is underappreciated… I take my dad’s place as boss, I’m not a nice guy…we get in a plane crash…she’s way more equipped to survive than I am, so I become kind of her captive.”
Josh Safdie
[26:15–35:32]
Accolades for “Marty Supreme”
- Marty Supreme boasts nine Oscar nominations, 11 BAFTA nominations, DGA nomination, and is A24’s highest-grossing film.
- “It’s a crazy, surreal feeling…as big as it is in scope, it’s a personal movie. And all my films are personal.”
— Josh Safdie, [27:22] - Jokes about doing 2-hour Q&As for three people in the audience during his early indie days.
Timothée Chalamet & Character Prep
- Timothée Chalamet stars as “Marty Mauser”; promoted the film conceptually in character.
- Film is about “a dreamer…hardcore dreamer whose dream no one respects…he’s going to go to hell and back to try to pursue greatness.”
— Josh Safdie, [28:40]
Attention to Detail & Production
- Praises production designer Jack Fisk for recreating 1950s New York with incredible authenticity:
- “I want you to create a time machine. Because this is not a period film. It’s a contemporary movie that I shot in 1952.”
— Josh Safdie, [29:44]
- “I want you to create a time machine. Because this is not a period film. It’s a contemporary movie that I shot in 1952.”
Makeup, Eyeglasses & Physical Transformation
- On Chalamet’s character having real, strong prescription lenses:
- “What I want to do is put plus 10 contact lenses in your eyes and then negative 6 prescription eyeglasses in front of them…Because, when the glasses fall off, you can see he really can’t see.”
— Josh Safdie, [33:13–34:35]
- “What I want to do is put plus 10 contact lenses in your eyes and then negative 6 prescription eyeglasses in front of them…Because, when the glasses fall off, you can see he really can’t see.”
- “This is the attention to detail that I’m talking about with Josh Safdie.”
— Jimmy Fallon, [35:23]
Notable Quotes & Memorable Moments
- Jimmy Fallon, on TrumpRx: “Trump RX is the only pharmacy where the dosage instructions are: ‘A lot of people are saying two.’” [01:33]
- Halle Berry, on marriage rumors: “I did not say no. We just don’t have a date.” [11:01]
- Dylan O’Brien, on Rachel McAdams: “She’s the most grounded…to so many people she’s such an entity…she’ll be like, I played a bully in high school, and I’m just like, are you talking about Mean Girls?” [21:10, 22:20]
- Josh Safdie: “It’s a movie about a dreamer…he’s going to go to hell and back to try to pursue greatness.” [28:40]
- On production detail: “I want you to create a time machine. Because this is not a period film. It’s a contemporary movie that I shot in 1952.” [29:44]
Timestamps for Key Segments
- TrumpRx monologue & opening jokes: [01:13–02:51]
- Valentine’s sketch "Get Freaky in the Winter": [02:51–05:17]
- F1 sequel teaser parody: [05:20–05:56]
- Disney Haunted Mansion quip: [06:04]
- Super Bowl Superlatives: [07:40–09:30]
- Halle Berry interview: [09:49–17:11]
- Dylan O'Brien interview: [17:47–25:49]
- Josh Safdie interview: [26:15–35:32]
Episode Tone
The show maintains Jimmy's trademark playful, fast-paced, and lighthearted style, peppered with inside jokes, plenty of laughter, and mutual appreciation among the guests. Fallon’s interviews are enthusiastic and warm, giving room for guests to share both personal anecdotes and behind-the-scenes industry insight.
This summary captures the episode’s major moments, humor, and interviews, preserving the energy and tonal rapport fans expect from The Tonight Show Starring Jimmy Fallon.