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Living my life the way I was was scarier to me than dying. Like most people, I was digging for answers. God led me to the answer and I started just putting the pieces together.
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When things don't make sense on the labs, modern medicine just gives up.
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If there's an epidemic or a pandemic, it is hormone resistance. We really need to be considering how do we get ourselves more sensitive to hormones?
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The body has an incredible ability to bounce back from, from absolute abuse.
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If you remove the interference, the body heals. Everything's about survival. More is not better and potentially even devastating for you. The key is adaptation, and if you don't adapt, you end up causing more inflammation later.
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How do I embark on a cellular anti inflammatory journey?
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All my cellular work that I teach comes down to ultimate human.
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Hey guys, welcome back to the Ultimate Human podcast. I'm your host, human biologist Gary Brecke, where we go down the road of everything anti aging, biohacking, longevity, and everything in between. Today we have a really, really special guest on the podcast today, someone I'm actually proud to call a friend. His family is biohacking in my rooms in the background. True, we've got somebody in a hocket machine, somebody in hydrogen bath, somebody in a red light bed. But Dr. Daniel Pompa is an incredible guest. Probably best known for his books on cellular healing and, and beyond fasting. But what I really appreciate and like are the healers that didn't just start out on a journey to be a healer. They started out on a very personal journey. When they start out on a journey to heal themsel and solve a person personal problem, I think that you find a very, very special type of healer, someone who introspectively really understands the journey of the people that they're trying to help and the patients that they're working with. So Dr. Pompa, I'm excited to have you on the podcast, man. Thank you for coming today.
A
Yeah, absolutely.
B
You know, I really like to, I mean, we're going to get into a lot of the specifics of, you know, just what beyond fasting is and, and, and, and your cellular healing diet and some of your, you know, your supplementation that you teach physicians to use to really get to the root cause of disease. But what I want to talk about first is your own personal journey. And ironically, we last connected at the center.
A
Yeah. Layla's clinic. Yeah, yeah.
B
And, and, and what I love about Leia, I love the scent in her family.
A
Yeah.
B
Just in general, for the entire mission.
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That they world changers, world Changes, World changers.
B
I mean, their school and the center for Healing, which is here in Miami.
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Amazing.
B
And I went to the grand opening of that. But she had a very similar, you know, personal journey and is now out there to find people that are on a similar journey and help them heal. So tell us a little bit about your journey as, you know, as a physician.
A
Yeah, it was all the way back in 1999, 2000, where I just got sick. I mean, I'd say, you know, fatigue. Just like most people I was training at that time. I was doing a lot of miles, 250, 300 miles on a bike, racing at the expert level, you know, lifting weights. Very busy practice. Two young boys at the time. So I thought I was just burning out, honestly, or, you know, at least over training. So I, like most people, I cut back on the training. Didn't help. I took off two weeks, which is, you know, unheard of when you're doing things like that, right? Two weeks, oh, surely I'll come back and feel good. I didn't. And then it went into headaches. Then it went into insomnia, where I would wake up, middle of the night, couldn't get back to sleep, couldn't get to sleep. Then the fatigue kept getting worse and the anxiety kept getting worse. So then gut problems started, which I never had. So you start chasing, you know, running from different foods. Is it this, is it that? And then I just like, even, like weird panic attacks, irritability, anger, sound sensitivity. Believe me, I'm brushing over it. It got very, very bizarre in the symptoms. And like most people, right, I. I chased it, right. My thyroid. It must be that because I had every symptom for thyroid issues. Even my hair thinning and adrenals were fried. I knew that. So I was trying to address those. And some things would get better, but most things were actually getting worse. And so I started going to different doctors, looking for answers. And, you know, many.
B
You're running a practice yourself.
A
I was barely. I mean, honestly, I. You know, it's bad when you look at your book and hope everyone's canceling. Like, you just look at it and say, okay, there's not that many people coming in today, thank God. But, you know, I, like most people, I was digging for answers, you know, going to different doctors. I remember running $5,000 worth blood work. Went to the top toxicologist, Allegheny General Hospital in Pittsburgh. Surely they're going to find something. And honestly, if they told me I had cancer, I'd be like, okay, at least I have something. Because no one's telling me anything. And now I can fight something, right? He came back and he looked at me and his exact words were, you're healthier than me, son. Of course, you know, at that point you look at you like you're crazy, right? So, yeah, that was not the response I wanted to, but I was looking, I was digging for stuff. I did a mercury test, blood test, because I found Mad Hatter's disease online and I, I had every symptom. Do you remember what that is?
B
I remember what that is. Where the hat makers would actually get mercury through their exact skin.
A
That's right, yeah. And it was part of the process that they used to attenuate different molds and that and the felt that they were using. But I had every symptom. I was mad as a hatter. So when it got the blood work back, I was disappointed it was negative. Fast forward now. I was working with a very bright endocrinologist. He said, dan, I think you have mercury toxicity. And I said, I thought so too. And I did this test. He says, well, that's the wrong test. If you were a Mad Hatter, you'd have poison, acute mercury poisoning, meaning getting exposed daily like the people making hats. It would show up in the blood, but I don't think that's it. I think it's more chronic. It won't show up in the blood or the urine. So he told me, challenge it out, it'll give you some reflection, but I think it's more brain mercury. And I did that. And sure enough, there was an odd pattern of all metals. And so I said, what test was that? If you. So it was a urine challenge using a water soluble chelator like DMSA or dmps. And it's good because it goes through the urine. There's. There's no perfect test for mercury. It's because the mercury that really affects us is deep in the tissue in the brain. And when it is that deep without biopsy, you know, you're oftentimes not going to see it. As a matter of fact, some of your most sick people from mercury or any heavy metal, oftentimes it looks like zero in the urine. So to answer your question, though, what test did I do? So doing a, a challenge with a water soluble chelator and then looking at the urine, it's a reflection possibly of what's in the brain. And so, you know, there was, you know, an answer because I had a lot of heavy metals that absolutely shouldn't have been there. Wow.
B
So you did this test, you find the, you know, you find the mercury and, and, and other metals which could have been like one of those Perry Mason tada moments. Like okay, now I, I've got an enemy. At least.
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True.
B
And then so talk about how you, what did you do afterwards? How did you go down this journey?
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The thing about it is if you go look online, I mean it, keep in mind this was back in 1999 or early 2000s at this point, you know, because I, I started getting sick in 99. But so imagine this being 2003. Not a lot online, right? Yeah, not a lot online now. Yeah, it true. But even still, it was still chaos and confusion, you know, meaning I would look and find contradicting information everywhere. I mean it's like very confusing. So literally I started reading studies dyslexic as a child, so I'm good at that. And I started digging and then I started calling the scientists. I started, you know, literally, you know, doing the homework to that level and I started just putting the pieces together. And I honestly say this, I, I went down a lot of false bad roads, roads that at least led to nowhere. And I learned things. But I'm telling you, God led me to the answer. And in my story, and I always have to give credit here in my story, we had two young boys at the time and people sick and challenged and not knowing what's wrong understand it's a huge stress on the other spouse or loved one. And my wife crying out for answers for me and the family and the kids because oftentimes she had to take the kids out of the house because I couldn't even handle the noise. And. Yeah. And you know, I, I didn't want to live. I mean it wasn't like I planned suicide, but living my life the way I was was scarier to me than dying. Wow. You know, because that, that's how horrible the feeling was. And again, it's hard to even put words to. And sometimes I don't even remember until I bring things up and I'm like, yeah, yeah. It's like I get goosebumps and teary eyed when I think about certain things like how I was with my kids. You know, I wasn't a good dad. I wasn't, I became someone I wasn't. Right. And that's where. But my wife always reminded me, you know, because at one point I said, you think I'm just crazy? And she says, no, you know, you, there's. You were normal and now you're not. But she was on her knees crying out to God for answers. And God spoke to her heart. Not an audible voice. Spoke to her heart. As she says, as clear as day. Not only am I going to get him, well, meaning me, but he's going to take a message to the world. Wow. And I wouldn't be on this podcast if that wasn't true.
B
I got goosebumps on that. You see what I mean about a personal journey having an impact on somebody?
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You know? And by the way, though, I have to say this, I. When she would say that to me, I didn't want to hear it. I would get very angry at her because my response was, I can't even get myself well. Don't put that on me. Yeah, right. But not seeing, obviously, what God saw. You know, I've been teaching doctors now what I learned in that battle. Yeah. For over 20 years. And now taking it directly to the person looking for answers, because that was.
B
Me, and I want to talk about that battle in that journey. So is this what led to the cellular healing diet? Is this where you.
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Yeah. You know, you start to put some things together to downregulate inflammation.
B
Right.
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And all my cellular work that I teach comes down to what is driving cellular inflammation, which is driving hormone resistance. One of the things that I realized is my blood levels of hormones were normal, even though I knew they weren't functioning. Right. I knew my testosterone wasn't functioning, or I knew my thyroid hormone. But when my blood work kept coming back normal, what I learned later is I had so much inflammation of the cell because toxins make their way into the membranes. Right. The outer membrane, inner membrane. I don't want to confuse people with too much science, but when that membrane becomes inflamed, you can't get the good stuff in the cell. You can't get the toxins out.
B
Yes.
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That cell becomes more and more toxic. Now genes start getting turned on, and the receptors to all your hormones are on the outer membrane, lipid rafts. Right. Hormones have to connect to those, get themselves in the cell or their message. And if that doesn't happen because the cells are so toxically inflamed, then you don't feel well, despite what your blood levels look like.
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Because we're measuring hormones and other concentrations of nutrients in the serum of the blood, but we're not actually measuring. It's interesting. I stumbled upon this myself. I was actually watching a Joe Rogan podcast one time, and this guy was on. He was talking about high levels of B12, marginally high levels of B12 being linked to cancer. And I actually went and looked the study up, and it was actually the deficiency in intracellular B12 that was leading to the cancer. And it was high outside of the cell because of the lack of utilization. So this is kind of what you're referring to. And I think it. This is maybe why it escapes. Let's just call it modern medicine for lack of better words. And not to attack, you know. You know, physicians that are trained to look at blood work, but you're looking at the serum concentration in the blood.
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Yeah.
B
And then you are assuming that the cellular metabolism is.
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Yeah. Dysfunction in toxic people. Yeah. Like I was. And by the way, when I went through this, I was a rare commodity. Right. It's like now, my gosh. I mean, you know, if you're in a room with 10 people, seven out of 10, you know, have some form of neurotoxic illness. You know, this. You see it. Right. And cellular inflammation driven by this problem creates hormone resistance. We understand it with insulin resistance. That means you have plenty of insulin in the blood. Oftentimes too much, but to your point. But it can't get it in the cell. It's not. The receptors blocked. That's resistance. Insulin resistance. Right. Thyroid resistance is happening, too. So that's why when people go and say, okay, finally my blood work is out of normal. Right. Give it another 10 years, maybe five years. Maybe mine would have been. They would have put me on a medication, made my blood work look normal. Right. People out there watching this are going, yeah, that happened to me. And you're saying, I still don't feel well. You know, my hair's still thinning. I still can't lose weight. I still have anxiety. I still. You know, it's like. It's because they improved your blood levels, but it's not getting. It's in the cell. Thyroid hormone has to get in the cell, hit the DNA, and all this. Wonderful things happen. You lose weight. Normal. You have lasting energy. No brain fog. Yeah. But the world today, honestly, if there's an epidemic there or a pandemic, it is hormone resistance.
B
Oh, my God.
A
Yeah. So it's like, look, there's a. There's a time and a place. There's a time and a place to take a hormone. Right. I mean, there's a time and a place to give those crutches. But we really need to be considering how do we get ourselves more sensitive to hormones. That's a whole nother topic. That's what I teach. That's how I got My life back, you know, and the other thing too is one of the things. When I started reading studies about mercury, I started reading most of it accumulates in different parts of the brain, which will drive different, you know, symptoms. One of the big places is the pituitary hypothalamus. Now, you and I know that controls your hormones, right?
B
Oh, yeah.
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Thyroid, your adrenals, that's the control tower. Your hypothalamus receives information from your body hormone levels, and then it tells the pituitary what it needs more or less of. Right?
B
Right.
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There's this perfect balance going on, and that balance is determined by that control tower. Well, mercury accumulates there, you know, and by the way, people in moldy homes, biotoxic illness, people that have been in moldy homes even years ago, that hypothalamus, those receptors get blunted to different other hormones.
B
Mycotoxins.
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Exactly. So again, there's the control tower that gets poisoned. Our cells, our cell membranes are affected by these toxins. And we're chasing the symptoms either with supplements, natural things or medications or hormones. Time and a place. But the point is, is you don't get a lasting result. You have to get to those causes.
B
You know, and, you know, what we see in the, in clinical practice all the time is people with relatively statistically low levels of hormone, with no signs of hormone disruption and no plenty of energy, sleeping well, performing well, keeping lean body mass on, not bloating, no weight gain, no water retention, no brain fog. And then people with optimal levels of hormones that are having hormone deficiency symptoms.
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Absolutely.
B
And I, and I think this is a hallmark example of how that could occur. And when things don't make sense on the labs, I think, you know, and a lot of times modern medicine just gives up.
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Sure.
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And they go, well, you know, you don't qualify for hormone therapy. You're a male, your testosterone's at 750, your free testosterone's at 1415. This is all in your head. But no, I'm exhausted, that's all. There's no libido and I can't sleep and I got brain fog. And, and so if, if someone's watching this podcast and they're identifying, first of all, which I think a lot of my audience is going to identify with, you know, some of the challenges that you face, maybe not to the level, but they, they identify with some of those symptoms, where do they start? Like, how do I embark on a cellular anti inflammatory journey? I know it's got to start with diet and lifestyle, but what Are some of the practices.
A
I mean, exactly. You know, my. So healing diet was coined that just because I'm like, okay, let's control what we can control, right? That drives cellular inflammation. You know, vegetable and can oils. Oils. Get rid of those. I always tell when I go to restaurants I'm allergic, right? It's like, you know, I'm allergic to these. No, if you hear us order, we do that. I'll make exceptions and eat some gelato, a little bit of, you know, right? It's like. But I don't make exceptions there. Those fats stay in your cell membranes for months, not hours, not days, but months. Driving cellular dysfunction. Inflammation, those hormone receptors, blunts them.
B
So it's also the sinister villain behind cholesterol. Cholesterol gets blamed for a lot of crimes it doesn't commit. But, you know, when you introduce.
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I'm a believer, cholesterol is one of the most important fats in the human body.
B
Yeah.
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So I am t. But yeah, I mean, so the. You know, these. Avoiding you. You asked where they start, like, let's stop. You know, the things that we know drive inflammation. Right? And diet plays a role. But look, I. I think that we. We have to realize that toxins are the number one driver of cellular inflammation, cellular dysfunction. And, you know, that's what I started teaching. My five Rs is a road map that I started teaching. There's a story about this, right? So. Of how to fix the cell. Because my point is, is that deep. Real detox is a cellular issue, right? Meaning that you don't. There's things we can do. Saunas are great. You and I love them. All these biohacks, we do them right. But if you don't upregulate cell function, then you're never truly going to have a lasting detox effect. The reason is because day in, day out, your cells are detoxing. When you make energy just to live, to think, ATP as we know, it's a dirty process. It's. Right. It's a dirty process. Like burning wood in a fireplace. It makes smoke. If that damper's not open, that smoke's backing up in the house, you and your family die from the smoke, not the flames, right? Well, that's the cell. When that cell's inflamed, those toxins that your cell's making become endogenous. Meaning inside your cell. Now you've got a toxic problem inside your cell. Real detox is fixing that. That cell has different pathways that need to be fixed. If you're going to have a lasting result. There's a story behind the five Rs. I was lecturing to a group of doctors in California, and I was so excited. I was explained to them that, look, this is real detox. This is what's broken. This is why people don't feel well. This is why people's hormones aren't working. This is why. And I'm going through it, and you've lectured to enough audiences to know when you have them and when you don't. When they understand and when they don't. I. I left there so discouraged. I literally sat on the airplane like they missed it. I was the only excited one in the room. Right. It's like, yeah, I always find that all the time. That was a bad experience. So literally, I literally started praying because I'm like, there's got to be a way. And then the 5R, I'm telling you, I got it. An idea, picked up my notebook, the five Rs was born. What is it? I don't want to lose people in the science, but R number one is the obvious. You have to remove the sources. And I think today we're missing a lot of sources of why people don't feel well. So let's circle back to that. R number two is regenerating the cell membranes. I already explained that. The hormone receptors are in the membranes. Your. Your mitochondrial membranes is where we make energy. You know, the nuclear membrane. So you have these membranes that get inflamed, these membranes that determine. There's a saying. It's not my saying. Life and death begins on the membranes. Wow. Yeah. And I would.
B
I believe that.
A
Yeah. And I would ultimately say, well, you know, Bruce Lipton, I'm sure you probably. Yeah, yeah. I mean, he showed the intelligence, the innate intelligence. That means the inborn intelligence in the human body literally is in the membrane. That's what he determined. It's in these integral membrane proteins. Right. It's like he's spot on. Right. We used to think it was in the nucleus. No, it's not in the nucleus. If you take the nucleus out and he showed this out of a cell, the cell lives on and it even does its functions. It's a white blood cell. It will go after bad guys. Right. But if you destroy with enzymes these hormone receptors in the membrane. Dead. Instant death. Right. So life and death is in the membranes, and that's R2. If we don't regenerate them, we're never going to get. Well, you're not even. Get the good stuff in your Cell and the bad stuff out. It doesn't matter what supplements you take, what diet you eat. So we have to fix the membranes. R3 is restoring cellular energy.
B
Okay?
A
If you don't restore cellular energy, this is one parallel. There's something called the Gibbs free energy equation. That means that you need a certain amount of ATP2 molecules to make one molecule of glutathione. And glutathione is how your body deals with oxidation and inflammation and detoxification pathway. Right? That's how it's getting things out of the cell and renewing things. Right? So energy drops, glutathione drops. But here's what the equation says. Inflammation goes up. So now we're in this perpetual cycle, you see. And then R4 is you have to reduce inflammation and, you know, a lot of dietary things that we're talking about, these are sequential.
B
All the things that you need to do.
A
No, you work them as you can.
B
Right.
A
You know, but. And then lastly, R5, and this is a topic you love. Methylation.
B
Yep.
A
Methylation, glutathione and methylation parallel each other. One's down, the other's down, one's up, the other's up. They parallel each other. And the energy pathways, methylation, obviously DNA genes getting triggered, turned on and off. We have to reestablish. And that's the R re establish methylation. And look, I, you know, I know you, you know, you do a lot. Yeah, that's a fit. Yeah, that's your R right there. You know a lot about it. You do, and I appreciate that because people need to hear the message. But when people are sick and challenged, they often say, because you do a lot of the genetic testing, I'm always like, look, I, I just assume you're methyl depleted because people that are sick and toxic, I don't care what your SNP is, your genetic, your gene, you are depleted in methylation when you're neurotoxically challenged and not well. So no matter what, we have to re establish it. And obviously it's a big deal. There's a principle. You should find this gentleman, and I always give him credit for it. His name is Alan Vininsky. Dr. Alan Veninsky. The methylation priority principle.
B
Methylation priority principle.
A
Yes. And here's the principle and people are going to get a good lesson. What it shows is, first of all, all stress, physical, chemical or emotional deplete methyl groups simple carbon and 3 hydrogen. Because many reasons that you need that carbon and three hydrogens methyl group to activate a stress Response, you need it to turn off stress response, cortisol, adrenaline, all of it. Right. It's survival. The priority is it will use methyl groups for that survival mechanism first and foremost. Here's the problem.
B
The stress mechanism.
A
That's right, the stress mechanism. So it's prioritizing methylation to that. Now we also know that you need methylation to get rid of toxic hormones, four hydroxy estrone that can drive cancer and all these. So when you do a 24 hour urine hormone, you oftentimes see people who have dangerous levels of 4 hydroxy estrogen and or 16 and then their methylation's depleted.
B
Yes. And that's why even on the Dutch test, you see that the, that's the Dutch test comt. You'll see that catechol o methyltransferase gene mutation is actually on there right down by the E2 pathway. It says, you know, does. Is this working or is it not?
A
Yeah, and, and by the way, but people, that stress bucket, physical, chemical, emotional and it's at the top or overflowing, meaning. Yeah, you're a lot of toxic stress the body. I said this once, I'll say it again, the body doesn't know the difference of stress, physical, chemical or emotional. Once it builds up and that bucket is full, your methylation is being tagged. So the methylation priority principle is we're shoveling it to there. And what problem is, is now we're not protecting our DNA now we're not making proteins now we're not getting rid of toxic estrogen or toxic hormones or antigens. So you know that, that's a principle that I learned from him many, many years ago.
B
I'm actually going to look that up.
A
Yeah, yeah. Methylation priority principle. Yeah, methylation, yeah, you'll. You'll love it. Alan Vininsky.
B
Alan, credit Vininsky. All right, Alan, I'm coming to give you some credit and I'm reading your book if you've got one interview. All right, and I'll interview you. You know, I, I've had a lot of guests on the podcast and I get a lot of requests. I mean recently Dr. Gabrielle Line was, was on the podcast and she actually someone posted on her social media that I have a tendency and we have a tendency as, as biohackers. And she was actually absolutely right about this too. To be men, to talk about men, to service men, to always talk about male hormones and, and the journey that a lot of men have been on. I want to sort of transition this to the females for a moment and Female hormone therapy and pre menopause, perimenopausal women, postmenopausal women. You know how much of this cellular inflammatory cycle and these, these five Rs are affecting women that are pre or postmenopausal?
A
More. Yeah, yeah. Perimenopause. If a lot of things happen. Right. And women are hormonally more complex than men in a good way, it can work. It can work for them. Live longer.
B
I've seen both sides of that equation.
A
Exactly. Absolutely. Yeah. Okay, now we. We got to keep the ladies with us here. There's an answer. But more warm. Women are affected by autoimmune. More women have thyroid complications. And I, I think clear too. And let's talk about why. But after Covid, more women, I think 54% ridiculous number of women ended up with thyroid strain, struggle, diagnosis. I was like, wow. You know, because again, what happened in Covid very odd virus. If your stress bucket was already really full. Many people became what we call long haulers post Covid.
B
Right.
A
I think it's like one out of six. Now people are saying I still don't feel well since. Right. Maybe be of the therapies from it or who knows.
B
Right.
A
But you know, the complicating factor created a lot of. But look, a few things happen in perimenopause. Your hormones are adjusting. It's actually very normal to remodel. Bone estrogen levels are naturally coming down and you start to. Women start to lose bone. A lot of lead is stored in the bone. Matter of fact, most of it. Many women dump lead. I'll tell you another time. That happens during pregnancy. It's normal to lose bone during pregnancy, but out comes the lead. Four generations inherited lead in utero. Four generations.
B
Wow.
A
Yeah. So. And we also inherit the epigenetics, the genes being turned on, but. Meaning if your mom had lead, then you do in four generations. Wow. And this has happened to my wife. My wife, during perimenopause started getting different weird hormone things going on. Right. And we weren't just going to chase it with hormones. So we started digging. We did the Dutch test, okay. And her methylation was tanked. And we started. And she had a buildup of 4 hydroxy estrone. Her mother died poor. Hydroxy estrone is a toxic, potentially toxic estrogen metabolite.
B
Very good at binding water too. Which women.
A
And we know it can drive cancer, particularly breast cancer. Her mother had breast cancer. Wow. When about treating it, you know, standard way through medicine, chemo, etc ended up. Well, she was Considered a cure. And then 10 years later, because I said, joyce, you didn't really get to the cause of what's going on. You know, at that time, I wasn't Even sure. But 10 years later, she ended up diagnosed with uterine cancer. Two years later, she died. My wife was heading down the same exact road hormonally. Wow. Well, we were trying to support her methylation in every way possible, and it just wasn't coming up. And long story short, we did a heavy metal test. Same test I did. Her lead was off the chart. I mean, off the chart. Literally off the chart. And so I started reflecting my son, who had these GI problems.
B
She having the symptoms of just hormone toxicity.
A
Yeah, exactly. And some hormone things. And, like, you know, lead has a little pattern different than mercury.
B
Right.
A
She didn't have the same symptoms. I had a lot of joint pain up. Yeah, yeah. Mercury's fear, dude. I was bloated with fear, Anger, irritability, anxiety, you know, horrible feeling of dread in the middle of the night, I would wake up just with a feeling of dread. You know, horrible depression. You know, I had it all. So I became someone I wasn't. But my wife's symptoms were different. So my son had these GI issues. And we ate perfect diet, fed our kids. Amazing. Tested his lead off the chart. My next one, which we called the Banshee. And he had these skin things off the chart. They got their lead from the mother. She got her lead from the mother. I'm saying this to say, like, look, it's normal to lose bone. Out comes the lead. Mercury. Same thing. There's a study called the Drash study. It's a German study that showed. Sorry, ladies, but the number of silver fillings that you have or your mom is proportional to how much they found in the baby's brain on autopsy studies. Wow. And that's very, very accurate because these are autopsies from, you know, dead fetuses. And the amount of mercury correlated to the amount of fillings in the mouth.
B
Fillings.
A
Yeah. So we're born into some of these toxins. My point is, is that bucket that I'm talking about starts filling in utero, and then through life. You know what, Morty Homes, did you live in what? You know, what other exposures? Contact lens fluid. If you look at my story, I wore contact lenses in the 70s, 80s, and early 90s, so I wore them when they were new.
B
Okay.
A
But the. The saline solution had mercury in it. Wow. Yeah. So that's been banned in the 90s, but it went Right into our brains. Right. And of course, I had my own set of fillings. Right. So mercury was going, right. Those fillings contain 50% mercury. They vaporize mercury despite what anyone says. They vaporize mercury for the life of that filling into the brain. Mercury vapor crosses the blood, brain barrier turns to inorganic mercury, and there it's locked for life, despite forever chemical. Part of my process that I teach passion, that's how I got my life back, is how do we get this inorganic mercury that has a half life longer than we live out of the brain. That's a process. I believe I have the only safe and effective way on the planet to do it. And of course, now, Gary, now, okay, if you put mercury and aluminum together, opposing metals like that, they have a higher lethal dose value. Simply put, if you put them in a study, comorbidity, they kill. Yeah, they, Right, they kill more rats. Right. It's like in smaller amounts together than they do one higher than the other. Okay, so aluminum and mercury. You know where we're getting crushed with aluminum right now? And I know there's a lot of conspiracy in our air. They've put aluminum as one of the additives in jet fuel to make it more efficient. Dollars and cents, they're saving my view. We can make jets fly longer on jet fuel. We're going to save billions of dollars. Problem is, aluminum is one of. So it's creating coming down as acid rain in our water and our food. We're being crushed with aluminum. Aluminum, the mercury exposures. You wonder why we have a world full of brain fogged people. Yeah. You know, heading for neurological disaster.
B
I'm a 0.1 micron air filter in every room in my house. Yeah, there's one right there.
A
Yeah, yeah. Because I mean, we are exposed. Whether you like it or not, when you go outside on certain days, you're going to be exposed to higher levels of aluminum. But regardless, it's in the water. You're filtering all your water. So am I right? But how many people aren't? And then you wonder why we have an explosion. I mean, Even the last 20 years of thyroid conditions, I mean, just skyrocketing.
B
Insane.
A
Yeah. Well, we know mercury and aluminum affects thyroid. The thyroid is the canary in the coal mine, meaning it's the most sensitive to neurotoxins. And we date ourselves a bit. But the canary in the coal mine means that they literally, in the old days, they didn't have a sophisticated equipment to like, you know, bring down.
B
Know what that means?
A
Yeah, yeah, yeah. I knew you did. I don't know if they do.
B
My cameraman.
A
Yeah, exactly. You guys know what that means? Yeah. See, they're saying, no canary in a coal mine. They literally brought a canary down into the coal mine. If the canary died, they said, we only have, like, so much time to get out because the canary was that sensitive. And they use canaries in the coal mine. Thyroid is the canary in the coal mine, meaning it's the first to go.
B
Right.
A
So if people suffering from thyroid symptoms. And again, you have thyroid dysfunction. Years. Years. Brodo Barnes says 10 to 20 years before you actually have a blood test that shows you're out. So that means you're having the dry skin, the brittle nails, the. The hair thinning, the low energy, the brain fog, constipation. All those are thyroid symptoms. You have that before your blood work goes out, Right.
B
Probably going back to your receptor sensitivity discussion where it's actually, you know, the receptor desensitization starts, which actually makes the hormone level less important. And now you're. And then eventually your hormone level goes down.
A
Yeah, Right. But then we go to our doctor, and then he puts us on a medication, makes our blood work look normal. And we go. We go back in a couple months, and he says, well, you should be feeling better. And you're going, yeah, I'm not. Yeah, okay. I might have a little more energy. I might be. But, yeah, I'm not feeling better. Last. It's because. Because they didn't deal with the cell, right? My saying is you have to fix the cell to get well if you don't do that today. Because that's why people don't feel well. Despite diet change, despite taking hormones, despite. Name the list, the supplements they take. I. That message was not even hitting 20 years ago. Now it's like, yeah, that's me. You know, I'm doing all that. I still don't feel well. It's a cellular issue. You have to upregulate those pathways. And then now we can get our cells functioning. Now all the stuff works. Now your supplements works, your diet works, you start los again. So anyway, that's.
B
I. I love that. So we, you know, so for females, you know, that are. That are menopausal, and they're actually starting to. They look at their hormone profile and everything seems normal. But, you know, they really just don't feel well emotionally, physically, they're not sleeping well. They've got the, you know, the classic water retention. You know, we call it the estrogen band, but they got the classic estrogen band. They've got brain fog dog and, and once in a while, and I see this profile come through our clinics all the time. They'll say there are just days where I have crushing fatigue and other days where I'm just tired and then once in a while I feel normal. But it's, it's, it's occasional. So where does that woman start filtering her air, filtering her water? Because she's not going to get a standard hormone panel because that's going to tell the same story that you were talking about.
A
Exactly.
B
What are some of the ways that they can test for some of these toxic levels of metals or mycotoxins? Hi guys. Gary here. I want to take a few minutes of your time to invite you to my ultimate human VIP community. This is a private community with front row seats to my most advanced health protocols, exclusive monthly Q and A calls, a private podcast where you can ask my guests and me your most pressing questions and my own personal wellness blueprints and everything you need to optimize your health. You'll connect with like minded folks in this community. You'll get firsthand access to cutting edge insights and enjoy special discounts on products that I trust the most. And here's the best part. Membership is just 97 bucks a month, a fraction of the cost my private clients pay for the same deep dive guidance. If you're ready to supercharge your wellness and skip the guesswork, I'd love for you to join us. Head to theultimatehuman.com VIP that's theultimatehuman.com forward/vip right now to become one of my ultimate human VIPs. This is your fast pass to better health, so don't miss it. Now let's get back to the ultimate human podcast.
A
Yeah, look, I, I always start with a simple test. I, I did a, a webinar that's free online. People can watch it.
B
By the way, I'm gonna put links to all of these in the show notes. I'm going to put links to beyond fasting in the cellular healing diet because.
A
If they go to pompaprogram.com there's, there's a webinar there that's free. It's what I taught doctors. Same information I taught doctors for 20 years and I explained this right? But I always say start with a simple cellular inflammation test where you measure melon del to hide it looks at basically membrane oxidation, which is a reflection. It's better than a CRP for specifically what we're looking for, right? Because you reactive protein is just a general, general inflammation. Right. And you know as well as I do, unless you're in a really sick state, most people will come back pretty normal. Right. Even though we have an optimal range, but the cell inflammation is way more sensitive. And yours would be under three. It would be very good.
B
Right.
A
You know, but most people today, it's not. And that will be like, oh, yeah. Well, that's why my hormone receptors, that's why my hormones aren't working. That's why. So we start people there and then, you know, what we do from the test is, okay, meet with someone. Then you, you know, help people look at their lives and identify what I call their perfect storm. So think about this. Everybody out there, when we see someone's bucket overflow, and they say, now I'm fatigued, now you know, all the symptoms we're talking about the anxiety, the depression, the, you know, you name it, the hormone challenges, basically, they, they get to the point where, like I said, the, the bucket overflows. But there was three stressors that came together. So I have people try to figure out where those stressors are, meaning we want it to be one thing. I did have mercury toxicity, but I was also living in a low grade moldy home. I was also doing 300 miles on my bike. Physical stress, mold, biotoxic stress, and mercury is another stress boom. My bottom fell out. The perfect storm. You remember the movie? We're dating ourselves again. George Clooney. Three weather fronts come together. It was. That was the eight. Was that 80s or 90s?
B
I was. Hopefully it was the 90s because it feels like it was yesterday.
A
Yeah, right. I know, it's so true. Yeah. George Clooney kind of looks the same. But anyway, three weather fronts come together. Catastrophic storm.
B
Right.
A
That's what we see.
B
They're all rotating the same direction.
A
So similar kind of what you're saying, intensity builds up. Yeah. So when we're, when we're evaluating people, we're looking for that perfect storm of three stressors. And then we say, okay, what can we do to get rid of those three stressors? And then we can really get to the solution. So let's talk. Cause I said our number one, let's circle back to it. I think that functional medicine has taken a turn to the left, maybe a not such a good turn, Meaning we were really excited about a lot of expensive tests, but ultimately it's moved further away from getting to the real causes. Right. So if I didn't get to the mercury in my brain, I wouldn't have got my life back if I didn't remove the fillings that were pushing mercury into my brain. I wouldn't have got my life back here. Yeah. And if you're still living in a moldy home unknowing, I know you don't smell it. You probably had an air test done, all came back normal. Right. But that doesn't mean you're not living in a moldy home. Right. Mold is very difficult to test.
B
Cyclical. I'm finding out, too now. Like, you can spore and then. And then sort of become dormant, and then it can sporulate again. So if you actually happen to be during. It's like hair, you know, it has a growth phase and a shedding phase, and, you know, mold has a similar phase. I don't. I don't profess to be an expert on mold by any means, but I did, as I've had. Had more mold toxicity clients, and I've been working with Dr. Minkoff in. In Tampa. And one of the things I've come to understand is that, yep, mold actually cycles too. So people will test their home, and they're like, hey, I tested negative for mold.
A
And, well, look at.
B
They're doing all the mold toxicity.
A
98 of all air tests come back negative. Right. It's like the molds behind the walls or it's somewhere. And some molds don't even spore. A lot like stachybotry.
B
Yeah, we're in the mold capital of.
A
The world right here.
B
Miami. Miami. And Malibu.
A
Yeah.
B
California.
A
Oh, yeah.
B
Listen up. If you live in Malibu, you know.
A
What it is, too? It's a lot of the H Vacs. So when I walk into a building, because I have a nose for it and I'm sensitive to it now, I walk in, I go mold. I turn around, walk out. Because, yeah, the H Vacs, they build up mold in the coil. Long story, but so it doesn't have to be behind the walls. Oftentimes it is in a H Vac, especially in humid areas. The point is, is that many, many people are sick because they're in a moldy home. You know, one of the symptoms are nasty. Weight loss, resistance, or all of a sudden, they gain weight. Hormone dysfunction, like crazy. Because biotoxins. We're not talking about a mold allergy here. There's mold allergies. You're allergic to the mold spore, but we're talking about the biotoxin, the actual mycotoxin. Right, the actual mycotoxin, which is A nasty, nasty neurotoxin, meaning it gets into the nerve tissue like mercury and it makes people really sick. You know, you get a certain set of symptoms. Frequent urination at night, frequent urination period. You get the insomnias, the anxieties, the inability to lose weight because it affects the leptin receptors in the hypothalamus. But the bottom line is you might be in a moldy home if we don't get to that cause. And today, to your point, the way we're building homes is we have a problem. You go to Europe, thousand year old buildings, they don't have mold. Why? It's the way they built the buildings compared to. We are their circulation. Yeah, circulation, exactly. We have drywall which has mold food on it. I mean, you know, drywall, it has paper. All you have to do is add water and you will have mold. Because the molds here, Right? Yeah. So it makes no sense. But we're still building homes.
B
I remember the big issue we had in, in southeast and southwest Florida with Chinese drywall.
A
Yeah.
B
Called the Chinese drywall toxic. And it was, was absolutely. I mean people were getting violently ill. I was actually in one of those homes where we actually had to, our builder had to. Was a community in Naples called Vasari. And our builder had to come in and remediate all. Everything beautiful home. And, and they had to literally come in and rip it down the studs and then ozone it and, and put the drywall back. But the, the exposure to some of these. So air filtration, things like, you know, ozone filtration systems, things like that, that we can actually put into our homes to really filter our air and try to. You know, I always tell people they should, they should build a, an imaginary fence around themselves and begin to filter things before it gets to their body. Absolutely. Because or else your temple is going to be the filter. So we can, we can filter our water before it gets to the temple or we can let our temple filter out the fluoride, the chlorine, the micro.
A
Well, when we walk outside, we get aluminum exposures and other exposures. Right. I mean, multiple exposures. Glyphosate, another chemical they're spraying on our food. It's in 60% of the rain. So we better control our environment. We can control right where we're spending 14 hours a day, 20 hours a day, who knows? But you know, that's what we have to control. So your point? You have to filter your water, you have to filter your air. Look, I know these things, you know, There's a price to it. But what's the price to your health? Right, right. You know, you, you and people out there don't just run and get your fillings out. There's a proper way to do that.
B
Biologic.
A
Yes. And then remember it's bioaccumulated in the brain. That's my process. We have to get it out of the deep tissue, let out of the bone, mercury and aluminum of the brain. You know, there's a process. But you ask the question, what can you do? You have to control the input of these things. Here's a great analogy. If we had a bathtub upstairs, all of a sudden overflowing, that's the symptoms we don't like. Right. Here's all the things, the damage being caused. That's the autoimmune condition, the thyroid condition, the diabetes, whatever condition it is you're diagnosed with or symptoms you don't like. And we can open up the drain, but if the water's flowing in more than the drain can drain because it's only this big, then we're not going to get well, we're going to still have damage happening until we slow down. We probably, we don't have to turn it all the way up. But if we slow down, what's going in, that's your response. And then we can now open up the pathways. And I argue we have to do that at the cellular level. You have to open up these pathways. We have to get our cells. If your cells are healthy, if your cells are able to do what God designed them to do, we're able to combat it.
B
Right?
A
Right. I'm not saying it's perfect. You know, we're overexposed today.
B
Right.
A
But you have to get your cells doing what they were designed to do day in, day out, and that's get rid of toxins. So let's pay more attention to that. Yeah.
B
Because, you know, very often of disagree with people that say, and I know it's a sort of a scientific law, the dosage determines the poison. But the truth is that sometimes the dosage doesn't determine the poison. It's the cumulative dosage that determines the.
A
Poison bioaccumulates in our tissue.
B
I mean, nobody ever got mercury poisoning from one piece of tuna fish. Right. I mean, they got mercury poisoning from micro dosing, for lack of better words. So you can have a safe level of mercury or safe level of arsenic or safe level of lead, and there are levels that are considered safe of all them of these things. But if you're not you know, if. If you're not eliminating these things from the body, then small accumulations eventually. Which is why, you know, in. In. In Europe, very often for toxicity levels, they'll use cumulative. Cumulative dose. Toxicity and say, hey, well, we can't allow this compound glyphosate, for example, because in cumulative doses, this is very toxic.
A
Yeah.
B
Somebody can eat some, you know, lettuce that has glyphosate on it, and they'll be fine. But if they eat that lettuce every day, that's a problem also on their apples and their oranges and their pears and their. And their peppers and their vegetables and their produce. Well, now all of a sudden, the body can't eliminate that.
A
Yeah. And so, and so you. You take in the toxic fish, the toxic lettuce, your body does what it does. Right, right. You know, and it gets rid of it because it's survival. Right. It's processing it, you know, to the point you made, but then it's overwhelmed and it's more. Then it's more like where we're at today, different even than 20 years ago. And now the pathways are breaking.
B
And is it. Would it be right to say it would take less to overwhelm it once it's in that state. So as soon as you hit the state.
A
Yes, absolutely.
B
Small assaults are. It's like sunburned skin.
A
Absolutely. You see, the people who are like, when I was sick, Gary, I would sit next to someone with cologne on. It would ruin. Not just that day, it would ruin several days.
B
Yeah.
A
I mean, one sniff of mold would put me really down. I'd tell, sensitive. I got. That's how filled my bucket was. I mean, wow. I couldn't. You know, I always, like, I. I get two glasses of water, fill one to this, like the top right at the edge, and then I fill one just a quarter of the way up. Right. I can stress this one a lot. No problem. That's. That's where you're at. Right. And me now, you know how many people are right at the edge. A little bit of stress and. And then all the damage, all the water overflow. We have to empty our buckets, and then you can tolerate more, then you can hit the fish. Then you can, you know, live a normal life. Because I hear it. I heard it from a guy just two days ago. He said, well, come on, aren't we just, you know, no matter what, there's toxin around? Like, you're right. That's why you have to build up your capacity to deal with it, otherwise you're going to trigger a gene, you're gonna end up with a thyroid condition, you're gonna end up with brain fog, fatigue. It starts there, right? And then the bad, then the cancer diagnosis could come, right? I mean once the cell gets more and more toxic, the DNA is going to get, get effective.
B
So, so in your protocol, you know, one of the things that you talk about in your book that I find really fascinating is creating new stem cells. And how does, how do we create new stem cells? Our stem cells are as old as we. Are you talking about releasing new stem cells? Because I, I, you know, I, I'm, I'm fascinated by, I think the whole field of biologic stem cells actually exosomes, natural killer cells, natural killer blood draws. I mean this, this sort of whole.
A
Area of biologic medicine, I'm fascinated too.
B
Yeah. So how does, how to, how does one go about increasing the number of their own stem cells without putting stem cells into their body?
A
Without putting stem cells in the body. So the cheapest way. Yeah, fasting. Yeah, look, I, I go, oh yes.
B
I want to go down this road. I'm excited to go down this road.
A
Yeah, I, I got into fasting in the 1990s. I literally visited these like fasting clinics who extend like, do you know, extended fasts with people like 30 days, 50 days, who.
B
We saw this this week. I just did a podcast. When did we do that? Three or four days ago with Dr. Valter Longo.
A
Oh, I love Valter. Yeah.
B
V is amazing. And I mean he's, he's like beyond intelligent. But what he let me know about, and he talks about it on the podcast, is that he is about to release a series of three clinical studies. They're finished with the trial and they're publishing it. One on Alzheimer's and dementia and neurofibrillary tangles and amyloid plaques, one on type 2 diabetes and, and another one on, on dementia. And the simplicity, for lack of better words, of using fasting to turn the power of the human body on these egregious neuroinflammatory conditions and things like diabetes. And he used the term, these are his words, not mine. These diseases are reversible.
A
That's it.
B
His words, not his words. And he said in this study, it's, they're going to prove that. So you know, I just took 55000 people, I think I had for three day water fast last month and I took another third 73, 000 people through a three day breath work challenge. But I want to go down this road of fasting.
A
Look, fasting, you wrote a book on it. Yeah. I mean, fasting's fascinating. You know what happens. And, and to go back, to answer your question, by the way, Valter is, you know, he really brought to the forefront partial fasting, where you don't even have to just do pure water. Now I'm a fan of both.
B
Yeah. I, I learned fast mimicking.
A
Yeah. Fasting, mimicking diet, which basically is a partial fast that means reducing protein and calories down below to a certain, certain point. Protein typically under 20 grams. Calories somewhere under a thousand.
B
Yeah.
A
Depending on body size.
B
Talking about.
A
Right? Yeah. And, and it works. I, I learned that type of fasting from a French gentleman and he, you know, read his books and his articles and because I, I noted that some people just. Fasting is a stress. And if you violate the premise of hormesis, meaning if you don't adapt to a stress, it becomes negative. So, and we can talk about that with the biohack. But what it is, what happens during this stress is the body goes into a survival mode and it starts crush it. Smart enough to get rid of the bad senescent cells. These are cells that live too long, drive inflammation, age you prematurely. Right. Cause all kinds of trouble. Zombie cells they're called. Right. Senescent cells. The body's smart enough to go after those and it goes after those to get the nutrition that it needs for survival. It's, it's fascinating, but it's so smart that it not only gets rid of, if it gets rid of a bad one, it stimulates a stem cell. And that was your original question, and it remakes a new cell. So Valter, in one of his studies, he showed that when you're in a fasted state, your body's getting rid of these immunosenescent cells. So these are cells that live too long in your immune system. Those are really bad because it gives you low immunity, it causes you to have hyper immunity autoimmune. Right. So we know that in a fasted state it's getting rid of those and it's creating a new cell, which he calls a naive cell, meaning we're chill, we're not going after the bad guys. And we're young, so we have great immunity. We're creating more of those guys. So. But you know, one thing that I loved about Volters, one of that you mentioned, the diabetes study that was first done in rats, he showed that it wasn't just one study, what they did in that study is once a month. They did a five day partial fast.
B
Right.
A
Next month. Five day partial fast. Next month, four months, I believe it was in that particular study. And they saw the beta cells in the pancreas regenerate.
B
That's what he was saying. And they actually did. Now they've done it, repeated it in humans.
A
Yes. And that's what he's working on right now.
B
And I don't want to misquote it, but it's in the podcast, what I want to say. He used large samples of patients and it was randomized and it was placebo controlled. And one of the groups was over 5, 500 patients. And, and the results were so profound that I think at one point they actually considered stopping the study. It seemed almost inhumane. But we're going to have randomized human clinical trials now from a world renowned, you know, researcher. And I think he's, he runs the Longevity center at usc, USC Davis and, and, and real, you know, instead of people having to make the extrapolation from rats into humans, which is amazing.
A
Yeah. Which they've been working on. That vulture has been a gift, you know, to this area.
B
Yeah.
A
When I was into fasting in the 90s, it was like me and some natural hygiene society people. I mean. No, it was.
B
You were.
A
Let me tell you something, this is a. Now I go to these seminars, right. Even the low carb events. Right. Keto events, etc. And now I see people fasting too much. Yeah. And they look gone. I mean it's like. And because fasting's a stress, right. Too much is not good. Too much autophagy, remember autophagy, meaning your body's getting rid of the bad cells. We just talked about the benefit of that. But that can go too much. Where you're now into that catabolic state. It's a breakdown state. There's a pathway that, that anti agers hate. It's called mtor. Now, I disagree. I think MTOR short term is an incredible pathway where we build muscle, we build rebuild ligaments, tendons, you know, it's a building pathway to their point. If you stay in MTOR too long, they can prove in studies that you age prematurely. So, but, so everything that stimulates mtor, elevated protein, this, that they hate. They hate, they hate. Right, Right. But look, autophagy is at one end, MTOR is at the other. Too much autophagy, no good. People are fasting too much. It's not good, it's too much stress. And then you have the MTOR pathway. Too much of that no good. You know, I teach in my premise diet variation, meaning moving in and out of different diets. Every culture, healthy culture on the planet did this. They did it because they had to.
B
Yeah. And his longevity diet, he talks about this too.
A
Yeah. And so it's like, so I've taught it for years. Go into ketosis, but go in and out of it. Do carnivore, don't stay in it. Right. I've, I've taught it for years. And by the way, you can look at the people that say keto causes cancer because of something called 4 hydroxynenolone builds up this nasty free radical. Wait, that's why it works in the beginning. That stimulates all these positive changes and then. But if you stay in it too long, it bioaccumulates, it builds up, up and then it becomes a negative. The same diet you're on, I could plant based diets. Too much plant based diets, eating plants, you have too many little toxic stressors that you know, can start inflaming the gut. Any diet too long causes problems. When you change a diet, you actually create a stress on the microbiome and actually create diversity. It's magic.
B
Yeah. This is metabolic flexibility.
A
Absolutely. But so one of the things I train my doctors and coaches is switch diets. Make people switch their diet. Switch their diet. More variation, more variation. I work that. It works.
B
And, and, and talk a little bit about for the people that are not super familiar with fasting. I mean, how does somebody harness the benefits of fasting without taking too much of a risk? Are you a fan? Because I was surprised by Dr. Longo said that he actually wasn't a huge fan of intermittent fasting, especially the very, the very narrow.
A
Yeah, I know that I've actually seen.
B
In our own clinical practice, you know, some of the worst endocrine disasters in menstruating females have been ones where with really, really narrow feeding windows. It's, it's an endocrine disaster for them.
A
I agree.
B
Tell them that like narrow their feeding window down to. They're highly disciplined. I mean we had a female crossfit athlete that have four hours a day was all she would eat. So she spent 20 hours a day fasting. It was a disaster for she actually ended up with something called red S. Yeah.
A
And this is the people I'm talking about fasting too much.
B
Yeah, it's anything too much.
A
You know, anything too much.
B
37 degree. You know we were about talking, were talking about this earlier. You know, I get in a cold plunge three minutes minimum, six minutes maximum. And I'm at 48 degrees. I'm not like, you know, 34 degrees and I don't stay in there for 12 minutes. But I see folks on, on, you know, Instagram, taking a snorkel, going underwater. They're underwater for 12 minutes, 37 degree water. And it's, it's kind of like a. Oh, you go in 37 degree water, I go in 34 degree water. You know, I go in 33.1. You know, it's.
A
After we finish the fasting conversation, I want to get back into that conversation.
B
But so my, my question essentially is that, you know, for somebody that's watch, watching this, hasn't participated in my fast, hasn't, hasn't read your book on fasting, isn't familiar with Dr. Valter Longo, what's this sort of a safe path for somebody to go down to experience some of the benefits of fasting?
A
Well, first of all, to your point, right, you know, everyone's different, right, like we were talking about, not everyone can jump in a callback for three minutes. And if they do, not only is more, not better, it's could be a lot worse. Yeah, yeah, they're not adapting. Everything is adaptation. If you don't adapt, you make a positive negative. Right. Same with fasting. So a lot of people are just, oh yeah, I, you know, they get a result. So they think by eating one meal a day, or maybe they are, they're eating in a four hour window to your point, right. And they lose some weight. But the problem is they might be losing a lot of muscle weight because their body's not efficiently burning fat, because they're not efficient at it. They've got cellular problems, right? And so what happens is then they're continuing doing this now. They're straining their adrenals, their thyroid, their hormones and they end up in this hormone down spiral as you described. To answer your question, what your fasting window works for you. Here's a good way you could do it. It. Okay, so people listening. So let's say you get up and you say, okay, I'm gonna skip breakfast and I'm gonna just push it out till 10 o'. Clock. Wake up in the morning. Let's say you wake up at 6 or 7. Check your, and they sell meters, very cheap, inexpensive meters for this. Check your glucose and ketones. Ketones are what? When your body burns fat, it makes ketones. Most of your viewers probably know what that is, right? And okay, so test both levels before you do anything. Before you have your coffee, before, whatever you do, do it first. Now at 10 o', clock, before you're ready to eat, test the levels again. What you should see is, and you could do three to five days so you get a good average. You should see glucose trending down from your weight, glucose and ketones trending up. If you don't see that, despite how you feel, you're not adapting to that level of stress. So let's see, your first meal is to 2 o'. Clock. You would test in the morning and then before 2:00 clock in, you should see that trend because what it's showing is at least I'm adapting enough that I'm burning fat and using that for energy. Now if you exercise or you know, do something or get stressed out, you're going to throw your numbers off as.
B
Opposed to seeing higher glucose levels, you're saying?
A
Yes, exactly. So then you see glucose training down, ketones trending up. It's a good sense that you're adapting to that. Okay. So that gives people a better sense of what fast works for them. But, but here, let me answer it. Even better for people. I'm okay. The app, you know, most people can do one or two days where they fast, where they eat one meal, a maybe in a four hour window. But the magic is in the feast. People are forgetting about that mtor pathway. The feast is the magic. So I go around saying, you know, you need to feast. Don't forget about the feast. I interviewed Karen Verde. You should interview her. But she, she was the first one to show. It was a mouse study, I believe, but they compared like low fat diets, low carb, you know, all these different diets. The, the diet that worked the best to break through weight loss resistance was actually feast. Famine. Feast Famine. Feast.
B
Really?
A
And I said, Karen, why was it. I think they were doing like low, like low calorie, one day, regular diet, low calorie feast, famine. Okay. I said, why is that? She said, because it forces adaptation and there's a hormone optimization that takes place when the body is in that state. The point is, is we're just famine. Yeah. In with intermittent fasting. And I, you know, you can't just do that much famine. You need feast days. Even from the simplest standpoint, your body, everything's about survival. Would you agree with that?
B
I would.
A
Everything. Right. That's why biohacks work. Right. Everything's about survival.
B
Probably why feast. Famine works so well.
A
Okay. Yeah.
B
It's very ancestrally in tune with your body.
A
But here's the thing. Look, your body, when you famine too much, it'll eventually go, I'm going to save Gary's life. And I'm going to slow my metabolism down. I'm going to hold on to fat, and if I have to, I'll even use muscle. It's easy, it's cheap. I've heard you say it, right? It's easy. 37, burn up the muscle, right? Gluconeogenesis. Boom. Okay? So it'll do that if it has to. And so you're getting lower and lower metabolism as that happens. Now, if you just take one or two days a week, people with hormone challenges oftentimes need three. Feast, famine, Feast, famine. And if you feast your body, it reminds your body it's not starving. Simple as that. So imagine you live in, you're in the middle of the wood in Alaska, right? Or you have a cabin in Alaska, and I do too, and I come over to your place in the heart of winter. This winter's colder than normal, harder than normal. You have a normal pile of wood that makes you get you through the winter. Typically, this winter is bad. So you're dwindling your pile very quickly. Matter of fact, so quickly you get nervous to survive, so you burn less wood. You turn the metabolism down. You're saying, you know what? I'm going to keep my house at 55 because I got to make it through this winter. I only have so much wood of wood. I come by your house and go, gary, holy cow, man, this place is freezing. Yeah, I'm running out of wood. I got plenty. I come over and dump a feast day. I give you more wood, guess what you do? You turn it back up to 70. Right? Right. You know what I'm saying? So that's what the metabolism does, you know? So the point is, people are putting themselves too much intermittent fasting daily, and their body starts backing into it. It may take months, but it backs into a survival mode. Screws your metabolism up hormonally, because that's what it is. That's what we've seen, you know, and then add feast days and watch the metabolism fire up. So they just remind your body it's not starving. It's not a rocket science here, right?
B
Yeah, you know, it's, it's, it's so funny because I, I, I just experienced that of my own accord, you know, I, I, I don't know that I necessarily do. Feast, famine, feast, famine days.
A
But I don't think we have to do it structured.
B
Yeah, yeah, but I take you Know, once in a while I'll just take a Sunday and I just fast on a Sunday and I'll just drink mineral water through, you know, throughout the day. And, and I wake up Monday morning and I feel so clear and so energetic. And then I eat normally on Monday. I actually wake up just as clear and energetic on Tuesday. And I've done this so many times that I know it's not, not just the fast, it's also the, you know, the feast of the feast afterwards. I don't think anybody can.
A
The hormone optimization that occurs.
B
Yeah.
A
Because of the feast.
B
Because I, I feel amazing. And when we did the three day water fast, I actually had people use bone broth day one and then eased into it days two and days three. And, and one of the most interesting things that people reported was that they didn't realize how much time they actually spent eating. Oh, they said, I wasn't hungry, but just behaviorally I got up and went through the refrigerator. I got up and went to the, you know, into the kitchen. You know, the office in the kitchen. And I usually walk in there four, five, six times a day because I'm constantly nibbling on, on snacks.
A
They say the average American eats 17 meals a day. And people go, no, I don't. But it's the bite of nuts, it's the olive. Yeah, yeah, yeah.
B
And it's, it's just constantly, you know, but it's still grazing.
A
But it still causes your body to have to process us that it's still a lot of energy to eat, you know. And Valter talks about this, Right. It was the, his predecessor was in the Human Genome Project. You know what that was? Yeah. Where they put themselves in a biosphere literally for like two years, ran every test on themselves. They diminished calories, I think. Was it 35%? I think it was because studies show that genes turned on that make you live longer.
B
Right.
A
It was a complete fail. And it was a fail because caloric restriction never works. Number one, they came out catabolic. Okay. And, oh, their gene, their SIRT1 gene was triggered to live. Wow. However, all their other parameters, they were an inflamed state. Their immune systems were horrible. Right. And their, their organs literally shrunk. Complete fail. That's when Valter said, wait a minute. We know caloric restriction is good, but short periods of time.
B
It's exactly what he said on the podcast. Yeah, yeah, it was a fascinating podcast because. Because he talked about yeast and then talked about mice and then talked about human trials. And now I think this Next series of clinical studies he's going to publish within the next week or 10 days or so, right around the time the podcast comes out is going to really rock the world of fasting because it's going to give real science and real data in randomized trials to the support behind caloric restriction for short periods of time.
A
That's the key.
B
And repeating that. I think that's the key. The study was exactly what you said was five days. And he has a, he has a fasting program called Prolon which is, you know.
A
Yeah, it's box, it's easy. I, I love it. I mean it's, it's easy because people go, well what do I eat right here, here's a box.
B
And I think it's easier to go to, to 800, 1100 calories a day than it is to go to zero calories.
A
Totally. Yeah. And by the way, he, he's, here's where I disagree with Valter and all respect to Valter. You know, he's, he's far smarter man than I am, but I do have clinical experience. He's against water fasting, but I see why. Because fasting is a stress. The average person, a pure water fast is too stressful for them. And it, it, they, you may not. You'll tap into muscle. A normal person will go, you'll lose a little muscle day one. And then growth hormone rises and then the body protects its muscle because it's in survival mode. Right. And it does all the right things. Very sick and toxic people, they don't go through that normal phase. So oftentimes the right things don't happen and you don't see as good of autophagy. So he's gravitated to partial fasting. But I like starting with partial fasting in the reason, for the reason most people are metabolic, metabolically challenged.
B
Right.
A
What do you say? What, what's the percentage of people are medically metabolically challenged in the U.S. i.
B
Would say over 70.
A
Yeah, okay. I've heard you say it. I'm like, I think I agree with that.
B
Oh yeah, yeah. No, it's, it's a vast number of people. So, so talking about the adaptation, you know, let's, let's ease into that discussion about biohacking because first of all, I'm a big believer in red light therapy beds. I'm a big believer in Nicole plunge. I'm a big believer in saunas. I just showed you my steam room. I filter, filter my steam before I go in there. I don't pro, I I follow sort of Valter's path 12 I. E for 12 hours and fast for 12 hours, which he says is a very safe zone to be in. And then once in a while I'll do a 24 hour or three day fast. I'm actually going to start doing his five day fast mimicking diet after this podcast. I am absolutely convinced that that's the way to go a couple of times a year. But talk about some of the, of the, the big biohacks that are out there, cold plunging, red light therapy, you know, some of these other big biohacks that are out there and, and the pros and potentially the cons of some.
A
Look, the easiest way to understand a principle called hormesis means if we stress a biological system, us, if we adapt, we get better, faster, stronger, healthier. If we don't adapt, bad things happen. Okay, yeah, understand that's a principle. If you exercise and adapt, you get stronger, faster, et cetera. So therefore we hire trainers, at least good athletes do, to make sure that we're adapting to the stresses that they put on. Studies show that if you don't create a stress, meaning if you're doing the same exercise all the time, you actually start getting Ben stop getting benefit and you'll even get a diminishing result. So we need over training. Exactly right. So anyways, most people when they first start, you know, they start reasonably, you know, or, or not they go into the gym and do too much. It's a negative. Right, right. So we understand we can over train, but this applies to cold baths. The only reason a cold bat or, or heat cold anything you just mentioned this premise of hormesis applies if you go in a cold bath, the body thinks it's going to die. What does it do? Raises up norepinephrine, which raises up growth hormone, which makes your, your cells more sensitive to hor major wonderful things happen.
B
Brown fat activation.
A
Oh yeah, brown fat activation, all of it. If you adapt. So no matter what, you feel good after because you know, you have this, you know, norepinephrine rise and all your, you know, good hormones come up. But how do you feel later that day or the next day? Because if you are tired, more tired, didn't sleep well, maybe you looked at your heart rate variability and it's dropping, you didn't adapt to the three minute cold bath. Maybe you need less than Gary or me.
B
Take it down.
A
That's not what's being taught. So people are just going, oh, I heard three minutes. I'm going to make Three minutes. I'm going to make three minutes. Many people out there, just like the fasting, can't adapt to that. And if you don't adapt, you end up causing more inflammation later. The key is adaptation. Saunas are the same way. And I said this to you earlier, right. I said when I was sick I couldn't even take hot showers. Yeah, you said that I would be just wiped out later that day. So I learned to take very lukewarm showers. I wasn't adapting to the heat. So people go into saunas because they hear an hour, whatever it is, and they force themselves to do it. More is not better and potentially even devastating for you. Wow. So we have people that have thyroid adrenal challenges, hormone challenges. I promise you they need less. Yeah. And you saw this one study that recently came out. A 10 minute shower or I'm 10 minute, 10 seconds of cold before your shower every day worked out better than the big cold plunge.
B
Right.
A
I believe they were just looking because they were looking at average people put the average person in a three minute cold plunge. When they looked at the results, it was not good. As good as the less stress.
B
Consistently less.
A
Consistently less long. All they did is lower the stress level and more people did better with that.
B
Right.
A
And I, and I believe that's the case for many of these biohacks.
B
And I could, I, I can absolutely see that too. So sort of bringing everything full circle from your, all of your experience, your personal journey, you know, your, your cellular healing diet. What are the big takeaways that you want people to remember from this podcast because they've heard a lot. I got to filter my environment, I got to take care of my cells. I, I should intermittent fast with too short of a window. What are the big three or five takeaways that you want them to walk away from? You know, I would say that one of them for me is that you can heal from whatever you're being challenged with right now. So that, that is the first like message is that the body has an incredible ability to bounce back from, from absolute abuse. I mean, from. You were, you know, just horribly abused in the state that you were in. So I mean, I want to give people hope that have, you know, chronic conditions that they just are, they just reached the end of the rope and they're exhausted on. But what are the big takeaways that you want them to.
A
You know, one of the things I always say is the only reason I'm qualified to help you and those people is number one, I was called to It. Right. I didn't choose it. But the only reason I'm qualified is because I was you. Right. If you are going to help drug addicts and alcoholics, you better darn be. You better have suffered and overcame it. Right. And that gives you the authority because one day they're going to say, you don't know what it's like. Like, yeah, you don't know what I feel. Right. I know what you feel. I know what it's like and that's why I'm qualified. But that gives you hope. There is an answer. But what I want you to hear to answer your question is there's a cause. And I think that alternative medicine has moved further from getting to the cause. Even when I first started lecturing on stages, it seemed like people got it NDS, DCs, MDs, at least that were there in that room. Yeah. Cause let's remove it it today. It's almost like we got too fancy. We're forgetting about these major causes. Neurotoxicity is rampant because of what we're under today. I think most people agree with that. But again, it's not as simple as just sitting in the sauna that we love. I mean, there's benefits to saunas, don't get me wrong. And you should do them, but you do have to get to the cell. Right. And I've spent 20 some years teaching doctors the principles and my kids. I think we had this conversation because your kids work with you, right?
B
Yeah, they do.
A
They saw me. They saw me on this, you know, treadmill of teaching doctors and even one on one helping people. And they said, dad, if you were called to take this to the world, it's not happening. It's not going to happen the way you're doing it. Yeah, that's an honest conversation.
B
That actually sounds like something my daughter.
A
Yeah, exactly. And I said, yeah, but embarrassing detox isn't. Here's a box of pills. It has to be specific for everyone. The doses, you know, with chelators, with binders. I mean, it's different for everyone, son. So, you know, anyways, you know, he had a different vision of how we can take this to the world, directly to the person looking for answers. And I, I say that to give, you know, to give people hope. So that's what we did. I mean, pump a program as, as you know, it, it's direct to the person hurting, you know, direct to the person looking for an answer as opposed to me trying to change, train the doctors. But there is hope. You have to get to the cause. If you remove the interference, the body heals. It does.
B
I love that.
A
It's a dang principle that works. I didn't get well because of specific vitamin. I got well because I got the mercury safely and effectively out of my brain. I got well for taking the biotoxins that were accumulated in my cells, downregulating every bit of cellular function that was should be there to protect me. You know, I got better by getting rid of that. So, you know, we are so is society. We are so about what we can add. But most people today aren't sick because of a lack of a vitamin. And I'll name five vitamins that I think are very important people lack.
B
Okay, Right, right.
A
But most people are sick because it's too much of something. These neurotoxins we're being inundated with. And I'm telling you, it's wearing people out. I mean, we never had a society with as much brain fog and anxiety as we do now. These are neurotoxins. Six signs, Gary. Yeah. You know, and people, if you don't get to the cause of that, I don't care how much kava CBD you take, I don't care what you do, how many biohacks you do, you got to get through the cause. And that's the message I really want people to hear.
B
That's excellent. How do people find you? I mean, how do you find you on Instagram, obviously.
A
Yeah, you can find me on Instagram, Dr. Pompa. You know, I. I have a following there. I put out videos all the time. We're talking about that because my kids make me do that too. You gotta educate dad. My whole social media like, me too, Anyways, but you know, pomprogram.com you can watch. I said that. There's the. The free webinar there. You can watch. But yeah, no, I mean, you can get. I'm out there. Okay.
B
Yeah, I am. And every podcast the same way, by asking every guest the same question. And there's no right or wrong answer to this, but what does it mean to you to be an ultimate human?
A
A human.
B
The ultimate human.
A
The ultimate human in. In your purpose, functioning in your purpose now. And. And I'll tell you, and I want people to hear this because I get this question. Well, how do you know? Or how do you find your purpose? Okay, if we look at our skill set, kind of tips to what we should be doing. Look, what you love, that kind of leans to it. But most importantly, look in Your pain, your pain leads to your purpose. So my wife and I have a saying because we've been through a lot of pain stuff in our life, from pain to purpose. And I'll broaden it even further. I do believe God has a promise for everybody. And the promise, you know, when we crying out for an answer, he gives us a promise. But here's the problem. As humans, we're always afraid to step into the promise. And something happens biblically. If you go through the Bible, there's something that's when it says be strong and courageous. The Hebrew words are rock hazakamatz. And you know, I'm no Jewish scholar and I'm not Jewish, but those words mean a whole lot more than the English words. The English words be strong, courageous, don't do it justice. Rakazakamatz means that God has already went into the promise for you. And whatever fears that you have, whatever kept you from stepping in or keeping you from stepping in, he deals with it. It's him, his strength, not yours. So as Israel was about to cross the Jordan, all they saw was 31 armies, and all they saw was disaster. God spoke through Joshua. Ra chazakamatz Israel, meaning I've taken that walk into the promise. If you look everywhere in the Bible, there's every time someone's about to step into a promise God has for them, God will send someone rock Kazakh mats. So the greatest hope is rock Kazakhmots. God's done it because people, we have fears even we hold on to, even our sick identities. Yeah, but, you know, but so true. Yeah, but walking don't have this because I know I didn't have any faith in myself or my strength or my abilities or my anything. But if, you know, God does it and he'll just step in to the promise, he'll do it.
B
That's amazing. That was an amazing podcast, man. Thank you so much for coming on. This was I so I thought it was going to be great. So much better than I thought. I'll put all of the links to what we discussed in the show notes below. And as always, guys, that's just science.
Podcast Summary: Dr. Daniel Pompa: How Heavy Metal Poisoning Destroys Your Health
Podcast Information:
In this compelling episode of The Ultimate Human, host Gary Brecka welcomes Dr. Daniel Pompa, a renowned expert in cellular healing and heavy metal detoxification. Drawing from his personal battle with chronic illness, Dr. Pompa shares invaluable insights into how heavy metal poisoning can wreak havoc on our health and outlines effective strategies to combat these toxins at the cellular level.
Dr. Pompa opens up about his own health struggles that began around 1999-2000. Despite being a physician, he experienced unexplained fatigue, headaches, insomnia, anxiety, gut problems, and other debilitating symptoms. Traditional medical tests failed to identify the root cause, leading him down a frustrating path of misdiagnoses and ineffective treatments.
Notable Quote:
Dr. Pompa (00:00): "Living my life the way I was was scarier to me than dying."
His quest for answers led him to suspect heavy metal toxicity, specifically mercury, after experiencing symptoms reminiscent of "Mad Hatter's disease." Initial tests came back negative, but persistent investigation and advanced testing methods eventually confirmed high levels of mercury and other heavy metals in his system.
Notable Quote:
Dr. Pompa (07:05): "There was an odd pattern of all metals. And so I said, what test was that? It was a urine challenge using a water-soluble chelator like DMSA or DMPS."
Dr. Pompa explains that many chronic health issues stem from cellular inflammation, which leads to hormone resistance. Despite normal blood hormone levels, the body's cells become too inflamed to respond effectively to these hormones.
Notable Quote:
Dr. Pompa (11:02): "When that membrane becomes inflamed, you can't get the good stuff in the cell. You can't get the toxins out. That cell becomes more and more toxic."
He emphasizes that modern medicine often overlooks this cellular dysfunction, focusing instead on blood serum levels that may not reflect the true state of cellular health.
Notable Quote:
Dr. Pompa (12:12): "The bodies have to adapt. If you don't, you end up causing more inflammation later."
Dr. Pompa introduces his comprehensive framework for cellular detoxification, known as the Five Rs:
Remove the Sources (00:35)
Regenerate Cell Membranes (17:01)
Restore Cellular Energy (20:43)
Reduce Inflammation (21:22)
Reestablish Methylation (21:29)
Notable Quote:
Dr. Pompa (19:49): "Life and death begins on the membranes."
The discussion delves into how cellular inflammation affects hormone sensitivity in both men and women. Dr. Pompa highlights that modern ailments like thyroid dysfunction are often the result of hormone resistance caused by toxins, not just hormone deficiencies.
Notable Quote:
Dr. Pompa (13:36): "If there's an epidemic or a pandemic, it is hormone resistance."
For women, particularly those in perimenopause and menopause, heavy metal toxicity can exacerbate hormonal imbalances, leading to conditions like thyroid strain and increased cancer risk due to impaired hormone detoxification.
Notable Quote:
Dr. Pompa (25:32): "Women are hormonally more complex than men in a good way. It can work. It can work for them. Live longer."
A significant portion of the conversation focuses on environmental toxins, including mercury from dental fillings and aluminum from various sources like jet fuel additives and household items. Dr. Pompa explains how these metals accumulate in the body, particularly in the brain and bones, leading to chronic health issues.
Notable Quote:
Dr. Pompa (30:08): "My own set of fillings. Right. So mercury was going, right. Those fillings contain 50% mercury."
He also addresses mold toxicity, emphasizing its insidious presence in modern homes and its impact on cellular health.
Notable Quote:
Dr. Pompa (40:16): "Mold has a similar phase. So if you actually happen to be during... it's like hair, you know, it has a growth phase and a shedding phase, and, you know, mold has a similar phase."
Dr. Pompa and Gary Brecka explore the role of fasting in promoting cellular health and detoxification. They discuss various fasting protocols, including water fasting and the fasting-mimicking diet proposed by Dr. Valter Longo.
Notable Quote:
Dr. Pompa (48:30): "Fasting's fascinating. You know what happens."
Dr. Valter Longo's studies on intermittent fasting demonstrate the body's ability to regenerate stem cells and remove senescent cells, contributing to longevity and reduced inflammation.
Notable Quote:
Gary Brecka (53:11): "They're gonna publish it. And one on the group is vegan because of something called 4-hydroxynenolone builds up."
The conversation transitions to various biohacking techniques such as cold plunging, red light therapy, and sauna use. Dr. Pompa emphasizes the principle of hormesis—the idea that moderate stress can enhance cellular resilience—but warns against overdoing these practices, which can lead to increased inflammation and hormonal imbalances.
Notable Quote:
Dr. Pompa (69:22): "The body thinks it's going to die. What does it do? Raises up norepinephrine, which raises up growth hormone, which makes your cells more sensitive to hor major wonderful things happen."
He advises a balanced approach, advocating for metabolic flexibility through alternating periods of stress (like fasting) and recovery (feasting).
Dr. Pompa concludes with several actionable insights for listeners seeking to optimize their health:
Filter Your Environment:
Support Cellular Health:
Adopt Balanced Fasting Practices:
Identify and Eliminate Toxin Sources:
Seek Personalized Detox Protocols:
Notable Quote:
Dr. Pompa (75:07): "The only reason I'm qualified to help you and those people is number one, I was called to it. I didn't choose it."
He underscores the importance of addressing the root causes of chronic illness rather than merely managing symptoms, providing hope for those struggling with persistent health issues.
This episode offers a profound exploration of how heavy metal poisoning and cellular inflammation contribute to chronic health problems. Dr. Daniel Pompa's personal experiences and professional insights provide a roadmap for detoxification and cellular healing, empowering listeners to take control of their health through informed, strategic interventions.
Resources Mentioned:
For more information and to access the free webinar discussed in the episode, visit pommaprogram.com.
This summary captures the essence of the conversation between Gary Brecka and Dr. Daniel Pompa, highlighting the critical discussions on heavy metal toxicity, cellular inflammation, hormone resistance, and effective detoxification strategies.