Podcast
The Y in Psychiatry
Hosted by NguyenInDoubt · EN
"The Y in Psychiatry" – a pragmatically endearing podcast talking to the med students, residents, fellows, and attendings of the medicine world about the nuances of psychiatry.
Each episode are discussions exploring the intersections of the mental health, medicine, and the human experience.
Together, we'll uncover the hidden "Y" – the compelling reasons, profound insights, and groundbreaking discoveries shaping the psychiatric landscape.
So grab a seat, warm beverage, tune in, and let's embark on this journey to unlock the mysteries of the human psyche, only on "The Y in Psychiatry."
Find articles on our episodes here:
12episodes
Episodes
Newest firstAll episodes
Cobenfy Unleashed: Psychiatry's New Frontier
3w ago00:20:04Tap to summarizeSend us Fan MailCobenfy doesn't block dopamine — and that's the whole point. In this special episode, we step away from the bipolar just a bit to unpack the first genuinely new mechanism in schizophrenia treatment in decades. We break down how Cobenfy pairs xanomeline (a brain-penetrant M1/M4 muscarinic agonist) with trospium (a peripheral blocker that curbs the side effects), trace its surprising betel-nut origins, and explain the why behind the how: quieting dopamine in the striatum for positive symptoms and boosting GABA in the prefrontal cortex for cognition — all without the D2 blockade that brings EPS, weight gain, and sedation.https://www.nguyenindoubt.com/theyinpsychhttps://feeds.buzzsprout.com/2185312.rss
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The Bipolar Brain on Overdrive: Dopamine, Serotonin & Circuits
Dec 300:16:22Tap to summarizeSend us Fan MailWe're now tracing how dopamine and serotonin imbalances map onto psychomotor agitation, depression, and that “too much energy” feel of mania. We also stop by the basal ganglia–thalamus–sensorimotor loop, the ventrolateral and ventromedial prefrontal cortex, the amygdala, and the superior frontal gyrus to show how disrupted circuits drive impulsivity, hyperemotionality, and goal-directed behavior. Say that 10 times.https://www.nguyenindoubt.com/theyinpsychhttps://feeds.buzzsprout.com/2185312.rss
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Ticket to Ride: The Bipolar Comorbidity Express Explored
Nov 2800:20:03Tap to summarizeSend us Fan MailAll aboard the Bipolar Express to unpack one of the messiest puzzles in psych: why diagnosing Bipolar Disorder sometimes feels like trying to solve a Rubik’s cube — when there could also be ADHD, anxiety, personality disorders, substance use, sleep-issues, or even childhood trauma riding shotgun. https://www.nguyenindoubt.com/theyinpsychhttps://feeds.buzzsprout.com/2185312.rss
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The B in Bipolar Stands for ‘Be Careful’: Diagnosing Bipolar Spectrum Disorders
Jun 10, 202500:23:53Tap to summarizeSend us Fan MailWe make a tokyo drift to a new topic: bipolarism! Lets jump in and manically (responsibly) get through as much as we can with depression and its interfaces. Hope you brought your shovel cause we're about to DIGFAST.https://www.nguyenindoubt.com/theyinpsychhttps://feeds.buzzsprout.com/2185312.rss
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Late Life Depression: When the Golden Years Turn Grey (and the SSRIs Don't Shine)
Mar 28, 202500:18:55Tap to summarizeSend us Fan MailIt never gets old to talk about late-life depression. Lets explore why growing older can sometimes mean growing sadder.We prance through executive dysfunction, vascular woes, inflammatory fires, and amyloid beta blues. We’ll discuss why SSRIs might not be the golden ticket and what alternatives, like dopamine agonists, rTMS, and even ECT, can brighten those grey years.Plus, we'll ponder if your patient is depressed, or if their brain is just throwing a vascular tantrum.Tune in, turn up your hearing aids, and fluid restrict for the next 20 minutes if you have the worlds smallest bladder.https://www.nguyenindoubt.com/theyinpsychhttps://feeds.buzzsprout.com/2185312.rss
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Liver and (Don't) Let Die: Navigating Psychotropic Use in Cirrhosis
Mar 21, 202500:18:49Tap to summarizeSend us Fan MailLets do the discussion tango between the liver and psychotrops: today we're focusing on patients with cirrhosis. Discussing 1st-pass metabolism, phase 1 and 2 metabolisms, plasma protein binding, fluid overload, and the implications of these processes on medication efficacy and toxicity.We know you liver this stuff.https://www.nguyenindoubt.com/theyinpsychhttps://feeds.buzzsprout.com/2185312.rss
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Kidneys don't Kid Around with Antidepressants
Dec 13, 202300:13:54Tap to summarizeSend us Fan MailLets explore the kidneys in psychiatry and discuss the impact of renal disease on medication management. No kidding these kidneys can be curiously be essential to know about for psychiatry.https://www.nguyenindoubt.com/theyinpsychhttps://feeds.buzzsprout.com/2185312.rss
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Forgetfully Down: Neurocognitively Impaired Populations and Depression
Dec 6, 202300:14:26Tap to summarizeSend us Fan MailExplore the intersection of depression and neurocognitive disorders in elderly patients. The discussion highlights the challenges in differentiating between depression and apathy, the importance of accurate diagnosis, and the appropriate pharmacological considerations for treatment. Don't forget to listen to this episode on your geriatrics rotation.https://www.nguyenindoubt.com/theyinpsychhttps://feeds.buzzsprout.com/2185312.rss
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More Potentially Impotent Side Effects from the Antidepressants - Part 2
Nov 29, 202300:12:25Tap to summarizeSend us Fan MailA continuation of Part one of potentially potent side effects of SSRIs - we now dive into the dark yet enlightening side effects of conventional antidepressants. From weight gain to sexual side effects and hyponatremia.Please dose this episode PRN throughout your career.https://www.nguyenindoubt.com/theyinpsychhttps://feeds.buzzsprout.com/2185312.rss
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Potentially Potent Side Effects of the SSRIs - Part 1
Nov 1, 202300:11:57Tap to summarizeSend us Fan MailWe explore the potentially potent side effects of SSRIs. This includes the risks of switching to mania, the role of mood stabilizers, the increased risk of suicidality in younger patients, and the common side effects of nausea and vomiting.This episode pairs well with some chamomille and a nice view.https://www.nguyenindoubt.com/theyinpsychhttps://feeds.buzzsprout.com/2185312.rss
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