A large trial in cardiac pacing finally published, PVCs and cardiomyopathy, cannabis, CV risk and the danger of observational studies, and the tale of two disparate statin trials are the topics John Mandrola, MD, discusses in this week’s podcast.

This podcast is intended for healthcare professionals only.

To read a partial transcript or to comment, visit:

https://www.medscape.com/twic

I BioPace Trial

Trial manuscript https://doi.org/10.1093/europace/euaf029

II Another Belief Challenged in EP this week—PVCs and CM ‘

UC Paper https://doi.org/10.1016/j.jacep.2025.01.004
JACC Review https://doi.org/10.1016/j.jacc.2024.03.416
Lee et al https://heart.bmj.com/content/105/18/1408

III Cannabis and CV Risk

Cannabis and MACE in JACC Advances: https://www.jacc.org/doi/10.1016/j.jacadv.2025.101698
Zeraatkar –Grilling the data https://doi.org/10.1016/j.jclinepi.2024.111278
PLOS-1 10.1371/journal.pone.0199705

IV Cardio-oncology

Jacc Onc Substdy https://www.jacc.org/doi/10.1016/j.jaccao.2024.11.008
Editorial https://www.jacc.org/doi/10.1016/j.jaccao.2025.01.006
STOP CA JAMA 2023 https://jamanetwork.com/journals/jama/fullarticle/2807988
PREVENT https://evidence.nejm.org/doi/10.1056/EVIDoa2200097

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Questions or feedback, please contact news@medscape.net

Mar 21 2025 This Week in Cardiology