Podcast
This Week in Virology
Hosted by Vincent Racaniello · EN
This Week in Virology is a netcast about viruses - the kind that make you sick.
53episodes
Episodes
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TWiV 1333: STING like a nanoparticle, float like HIV
5d ago01:54:50Tap to summarizeTWiV explains research showing how HIV-1 signalling remodels nuclear pores to licence infection, and development of STING agonist nanoparticles to enable coordinated mucosal-systemic immunity for durable pan-β-coronavirus protection. Hosts: VVincent Racaniello, Alan Dove, Rich Condit, and Brianne Barker Subscribe (free): Apple Podcasts, RSS, email Become a patron of TWiV! Links for this episode Support science education at MicrobeTV Positions in Rosenfeld Lab (email) Bundibugyo ebolavirus sitrep (WHO) Ebolavirus and Andes virus with John Dye (TWiV Special) Major research nonhuman primate supplier going out of business (Science) HIV-1 signalling remodels nuclear pores to licence infection (Nature) STING agonist nanoparticles enable mucosal-systemic immunity (Nature Nanoparticles) Timestamps by Jolene Ramsey. Thanks! Picks of the Week Brianne – Otherworldly music albums feature space weather data Rich – Evidence Mapping: Consolidating and summarising available evidence to support the demonstration of effectiveness of developmental vaccines, Australian Living Evidence Collaboration (ALEC) Alan – Holyoke dam fish elevator Vincent – 68 Quadrillion Underground Miles of Fungi Intro music is by Ronald Jenkees Send your virology questions and comments to twiv@microbe.tv Content in this podcast should not be construed as medical advice.
Transcribe →TWiV Special: Ebola virus and Andes virus with John Dye
6d ago00:57:08Tap to summarizeVincent travels to ASM Microbe in Washington DC to speak with John Dye of the United States Army Medical Research Institute of Infectious Diseases about the recent outbreaks of Bundibugyo ebolavirus in Africa and Andes virus on a cruise ship. Host: Vincent Racaniello Guest: John Dye Subscribe (free): Apple Podcasts, RSS, email Become a patron of TWiV! Intro music is by Ronald Jenkees Send your virology questions and comments to twiv@microbe.tv Content in this podcast should not be construed as medical advice.
Transcribe →TWiV 1332: Clinical update with Dr. Daniel Griffin
6d ago00:54:29Tap to summarizeIn his weekly clinical update, Daniel Griffin and Vincent Racaniello express concern about vaccine policy and ACIP, scaling back of the CDC’s role in global public health, shingles vaccine and dementia, new screwworm cases, the Ebola outbreak in the Congo and Uganda and where the hantavirus outbreak began, before Dr. Griffin deep dives into the measles outbreak, recent statistics on RSV, influenza and SARS-CoV-2 infections, the Wasterwater Scan dashboard, Johns Hopkins measles tracker, Virgina outbreak of measles, how to access and pay for Paxlovid, how more people were negatively impacted by influenza than COVID, discontinuing contact precautions for COVID, where to go for answers about long COVID-19, and contacting your federal government representative to stop the assault on science and biomedical research. Subscribe (free): Apple Podcasts, RSS, email Become a patron of TWiV! Links for this episode Today we filed a motion asking the First Circuit to expedite our appeal of the district court’s order in the AAP lawsuit that left ACIP—the nation’s vaccine advisory committee—without a quorum (X) CDC advisers drop decades-old universal hepatitis B birth dose recommendation, suggest blood testing after 1 dose (CIDRAP) HHS asks for expedited appeal of court ruling on US vaccine policy (CIDRAP) New Plan Scales Back C.D.C.’s Work on Diseases Abroad (NY Times) Zoster Vaccination and Dementia: Interpreting the Signal and Testing the Mechanisms (CID) Safety and Immunogenicity of 1 or 2 Additional Doses of the Adjuvanted Recombinant Zoster Vaccine Administered 5–6 Years After Primary Vaccination in Adults ≥50 Years (OFID) Dashboard SCREWWORM.Gov (USDA: Animal and Plant Health Inspection Service) CDC Activates Emergency Operations Center for New World Screwworm Response (CDC Newroom) Head-to-head comparison suggests flu was much more likely to lead to hospitalization than COVID last winter (CIDRAP) FDA Issues Emergency Use Authorization for Generic Over-the-Counter Drug to Treat New World Screwworm in Dogs and Cats (FDA) Fact Sheet: Emergency Use Authorization of Nitenpyram Tablets (nitenpyram) for New World Screwworm (NWS) (FDA) Ebola dashboard (ebola.fyi) EBOLA:The Democratic Republic of the Congo, 2026 (WHO) Bundibugyo virus disease outbreak Democratic Republic of the Congo (WHO: Democratic Republic of Congo) Ebola Outbreak: Current Situation (CDC:Ebola) Big Ebola outbreak puts spotlight on little known virus (Science) Ebola outbreak spreads to crowded displacement camp in Congo (Reuters) Ebola outbreak in DR Congo expands into large displacement camp (CIDRAP) Congo Ebola outbreak may be worst ever, Africa CDC says (Reuters) Advocacy groups are urging the release of the monoclonal antibody MBP134 and any other requested investigational therapeutics (Citizen.org) Hantavirus dashboard (Hantavirus.up Hantavirus on board with Prof. Vincent Racaniello (microbeTV) How did the cruise ship hantavirus outbreak start? (Science) Wastewater for measles (WasterWater Scan) Measles cases and outbreaks (CDC Rubeola) Big outbreak, bright lights…Measles Dashboard( South Carolina Department of Public Health) Utah measles outbreak response (Utah Department of Health and Human Services) UtahMeasles Dashboard (Utah Department of Health and Human Services) US measles cases continue to climb, especially in Virginia(CIDRAP) Measles (VDH: Virginia Department of Health) Tracking Measles Cases in the U.S. (Johns Hopkins) Measles vaccine recommendations from NYP (jpg) Weekly measles and rubella monitoring (Government of Canada) Measles (WHO) Get the FACTS about measles (NY State Department of Health) Measles (CDC Measles (Rubeola)) Measles vaccine (CDC Measles (Rubeola)) Presumptive evidence of measles immunity (CDC) <a...
Transcribe →TWiV 1331: A drug for cervical cancer
2w ago01:58:16Tap to summarizeTWiV explains research showing that dairy cows are infected with low doses of influenza A(H5N1) and do not transmit efficiently to other animals, and covalent inhibitors of human papillomavirus type 16 E6 protein that restore p53 function and suppress growth of HPV-driven tumors in vivo. Hosts: Vincent Racaniello, Rich Condit, Brianne Barker, and Angela Mingarelli Subscribe (free): Apple Podcasts, RSS, email Become a patron of TWiV! Links for this episode Support science education at MicrobeTV Positions in Rosenfeld Lab (email) Letter on Baric funding ban (Science, scroll to bottom) New political jobs at science agencies (Science) Ebola sitrep (WHO) Influenza H5N1 infection of dairy cows (Nat Comm) Drug for cervical cancer (PNAS) Timestamps by Jolene Ramsey. Thanks! Picks of the Week Angela – SpaceX Brianne – Honeybees and shrimp are now getting vaccinated Rich – “Carrying the Fire: An Astronaut’s Journeys” by Michael Collins Vincent – NTSB Reveals What Really Happened to United 169 Intro music is by Ronald Jenkees Send your virology questions and comments to twiv@microbe.tv Content in this podcast should not be construed as medical advice.
Transcribe →TWiV 1330: Clinical update with Dr. Daniel Griffin
2w ago01:11:05Tap to summarizeIn his weekly clinical update, Daniel Griffin and Vincent Racaniello opine on the recent executive order on the routine childhood vaccination schedule, the Ebola outbreak in the Congo and Uganda including the fast track trials for 2 vaccine candidates and antivirals, recent Hantavirus infections, use of quarantined “Hantavirus” patients for the governmental propaganda machine, use of ribavirin and other antivirals for Hantavirus associated cardiopulmonary disease, before Dr. Griffin deep dives into the measles outbreak, recent statistics RSV, influenza and SARS-CoV-2 infections, the Wasterwater Scan dashboard, Johns Hopkins measles tracker, the measles outbreak in Bangladesh, as well as in a daycare center in Texas in 2025, how to access and pay for Paxlovid, FDA approval of a second COVID-19 antiviral drug, where to go for answers about long COVID-19, use of convalescent sera for COVID-19 treatment and contacting your federal government representative to stop the assault on science and biomedical research. Subscribe (free): Apple Podcasts, RSS, email Become a patron of TWiV! Links for this episode Childhood Vaccine Hesitancy (NEJM) One Year In: Public Views of a Changing Public Health Landscape (Harvard School of Public Health) Rotavirus Vaccine Coverage and Potential Barriers Among US Children Born From 2007 to 2024 (Pediatrics) Texas reports New World screwworm in 3-week-old calf (CIDRAP) USDA Confirms First Case of New World Screwworm in a Dog in Lea County, New Mexico, Fourth Case in Texas (USDA: Animal and Plant Health Inspection Service) Confirmed Detections of New World Screwworm (USDA: Animal and Plant Health Inspection Service) Mexico reports more human New World screwworm infections (CIDRAP) Frequency and persistence of post-acute symptoms after chikungunya, dengue, Zika and malaria in travellers: a prospective multi-centre study (Journal of Travel Medicine) Ebola dashboard (ebola.fyi) EBOLA:The Democratic Republic of the Congo, 2026 (WHO) Bundibugyo virus disease outbreak Democratic Republic of the Congo (WHO: Democratic Republic of Congo) Ebola Outbreak: Current Situation (CDC:Ebola) Modeled Scenario Projections for the Ebola Disease Outbreak Caused by Bundibugyo Virus, 2026 (CDC: MMWR) Assessment of Riskto the U.S. Population from the Ebola Disease Outbreak Caused by Bundibugyo Virus, 2026 (CDC: MMWR) How Ebola Disease Spreads (CDC: Ebola) Signs and Symptoms of Ebola Disease (CDC: Ebola) Hantavirusdashboard (Hantavirus.up) Hantavirus on board with Prof. VincentRacaniello (MicrobeTV) Some hantavirus-exposed cruise ship passengers return home to finish quarantine (CNN) Use of tocilizumab for severe hantavirus pulmonary syndrome: a MEURI case series with contextual comparisons (LANCET: Infectious Diseases) First reported case of Andes hantavirus cardiopulmonary syndrome treated with a combination of favipiravir, ribavirin, icatibant and baricitinib (Clinical Microbiology and Infection) Wastewater for measles (WasterWater Scan) Measles cases and outbreaks (CDC Rubeola) Big outbreak, bright lights…Measles Dashboard (South Carolina Department of Public Health) Utah measles outbreak response (Utah Department of Health and Human Services) Utah Measles Dashboard (Utah Department of Health and Human Services) Tracking Measles Cases in the U.S. (Johns Hopkins) Measles vaccine recommendations from NYP (jpg) Weekly measles and rubella monitoring (Government of Canada) Measles (WHO) Get the FACTS about measles (NY State Department of Health) Measles (CDC Measles (Rubeola)) Measles vaccine (CDC Measles (Rubeola)) Presumptive evidence of measles immunity (CDC) Contraindications and precautions to measles vaccination (CDC) Adverse events associated with childhood vaccines: evidence bearing on causality (NLM) Measles Vaccination: Know the Facts(ISDA: Infectious Diseases Society...
Transcribe →TWiV 1329: How HIV-1 goes nuclear
3w ago01:50:33Tap to summarizeTWiV explains research showing limited transmission of cervid prions to nonhuman primates, and the finding that cone-shaped HIV-1 capsids are transported through intact nuclear pores. Hosts: Vincent Racaniello, Alan Dove, and Brianne Barker Subscribe (free): Apple Podcasts, RSS, email Become a patron of TWiV! Links for this episode Support science education at MicrobeTV Positions in Rosenfeld Lab (email) Ebola outbreak news (ECDC, WHO) NSF research grants on hold (Nature) Transmission of cervid prions to nonhuman primates (Sci Adv) Cone-shaped HIV-1 capsids transported intact through nuclear pore (Cell) HIV-1 reproduction video (Janet Iwasa) Letters read on TWiV 1329 Timestamps by Jolene Ramsey. Thanks! Picks of the Week Brianne – What We Need to do NEXT Re: OMB Rule Alan – Metallic Realms, by Lincoln Michel Vincent – TWiV 1: West Nile Virus Listener Picks Mark – How the Library of Congress packed 250 years of U.S. history into a vial the size of a quarter Intro music is by Ronald Jenkees Send your virology questions and comments to twiv@microbe.tv Content in this podcast should not be construed as medical advice.
Transcribe →TWiV 1328: Clinical update with Dr. Daniel Griffin
3w ago01:00:57Tap to summarizeIn his weekly clinical update, Daniel Griffin and Vincent Racaniello opine on the recent executive order on the routine childhood vaccination schedule, the Ebola outbreak in the Congo and Uganda including the fast track trials for 2 vaccine candidates and antivirals, recent Hantavirus infections, use of quarantined “Hantavirus” patients for the governmental propaganda machine, use of ribavirin and other antivirals for Hantavirus associated cardiopulmonary disease, before Dr. Griffin deep dives into the measles outbreak, recent statistics RSV, influenza and SARS-CoV-2 infections, the Wasterwater Scan dashboard, Johns Hopkins measles tracker, the measles outbreak in Bangladesh, as well as in a daycare center in Texas in 2025, how to access and pay for Paxlovid, FDA approval of a second COVID-19 antiviral drug, where to go for answers about long COVID-19, use of convalescent sera for COVID-19 treatment and contacting your federal government representative to stop the assault on science and biomedical research. Subscribe (free): Apple Podcasts, RSS, email Become a patron of TWiV! Links for this episode CIDRAP Op-Ed: What’s the likely next move after the executive order on childhood vaccines? (CIDRAP) Ebola dashboard (ebola.fyi) Epidemic of Ebola Disease caused by Bundibugyo virus in the Democratic Republic of the Congo and Uganda determined a public health emergency of international concern (WHO) WHO ramps up support to the Democratic Republic of the Congo’s Ebola outbreak response (WHO: Democratic Republic of Congo) Ebola Outbreak: Current Situation (CDC:Ebola) Race begins to trial Ebola drugs amid current outbreak (Nature) Three Ebola vaccine candidates fast-tracked as African outbreak continues (CIDRAP) CEPI fast-tracks three Bundibugyo ebolavirus vaccine candidates (CEPI) Obeldesivir (Wikipedia) Hantavirusdashboard (Hantavirus.up) Hantavirus on board with Prof. VincentRacaniello (microbeTV) Scoop: HHS asks confined hantavirus cruise passengers to assist in propaganda (Inside Medicine) Ribavirin (DrugBank) First reported case of Andes hantavirus cardiopulmonary syndrome treated with a combination of favipiravir, ribavirin, icatibant and baricitinib (Clinical Microbiology and Infection) Wastewater for measles (WasterWater Scan) Measles cases and outbreaks (CDC Rubeola) Big outbreak, bright lights…Measles Dashboard (South Carolina Department of Public Health) Utah measles outbreak response (Utah Department of Health and Human Services) Utah Measles Dashboard (Utah Department of Health and Human Services) Tracking Measles Cases in the U.S. (Johns Hopkins) Measles vaccine recommendations from NYP (jpg) Weekly measles and rubella monitoring (Government of Canada) Measles (WHO) Get the FACTS about measles (NY State Department of Health) Measles(CDC Measles (Rubeola)) Measles vaccine (CDC Measles (Rubeola)) Presumptive evidence of measles immunity (CDC) Contraindications and precautions to measles vaccination (CDC) Adverse events associated with childhood vaccines: evidence bearing on causality (NLM) Measles Vaccination: Know the Facts (IDSA) Deaths following vaccination: what does the evidence show (Vaccine) Bangladesh posts more than 1,300 measles cases, 2 deaths, in 1 day (CIDRAP) Measles Outbreak in a Child Care Facility — Lubbock, Texas, March–April 2025 (CDC:MMWR) Influenza: Waste water scan for 11 pathogens (WastewaterSCan) USrespiratory virus activity (CDC Respiratory Illnesses) Respiratory virus activity levels (CDC Respiratory Illnesses) Flu vaccine recommendations: Va...
Transcribe →TWiV 1327: Influenza viruses in the MIST
4w ago01:59:33Tap to summarizeTWiV explains research on human influenza virus transmission that reveals heterogeneous expulsion of infectious virus into air, and how gut bacteriophages dictate inflammation heterogeneity through tuning the phage-bacteria-sphingosine-intestine axis in Crohn’s disease. Hosts: Vincent Racaniello, Rich Condit, Brianne Barker, and Jolene Ramsey Subscribe (free): Apple Podcasts, RSS, email Become a patron of TWiV! Links for this episode Support science education at MicrobeTV Positions in Rosenfeld Lab (email) NIH ousts infectious-disease leaders (Nature) Measles deaths in Bangladesh (npr) Russel Vought is going to destroy American science (Elizabeth Ginexi) Heterogeneous expulsion of infectious influenza virus into air (Cell) Gut phages and Crohn’s disease (Cell Host Microbe) MIST device (Emory) Letters read on TWiV 1327 Timestamps by Jolene Ramsey. Thanks! Picks of the Week Brianne – The Perfect Bee Language Rich – Hubble’s Messier Catalog Jolene – A different kind of power – Jacinda Ardern Vincent – Albert Sabin by Karen Torghele Listener Picks Anthony – Dr. Dakotah Tyler Marcus – Apollo Intro music is by Ronald Jenkees Send your virology questions and comments to twiv@microbe.tv Content in this podcast should not be construed as medical advice.
Transcribe →TWiV 1326: Clinical update with Dr. Daniel Griffin
4w ago00:38:49Tap to summarizeIn his weekly clinical update, Daniel Griffin and Vincent Racaniello comment on incidences of locally transmitted malaria in the US, mpox diagnostics, the latest developments surrounding hantavirus infections, and the Ebola outbreak in the Congo and Uganda including vaccine candidates before Dr. Griffin deep dives into the measles outbreak, recent statistics RSV, influenza and SARS-CoV-2 infections, the Wasterwater Scan dashboard, Johns Hopkins measles tracker, the measles outbreak in Texas in 2025, how to access and pay for Paxlovid, where to go for answers about long COVID-19, casual association of auto-antibodies and COVID complications and contacting your federal government representative to stop the assault on science and biomedical research. Subscribe (free): Apple Podcasts, RSS, email Become a patron of TWiV! Links for this episode CDC Operational Guidance for Investigating Locally Acquired Mosquito-Transmitted Malaria — United States, 2026 (CDC: MMWR) Performance of five mpox antigen-based rapid diagnostic tests tested on lesion swabs from patients with suspected mpox from the Kinshasa province of DR Congo: a diagnostic accuracy study (LANCET: Infectious Diseases) Hantavirusdashboard (Hantavirus.up) Andes Hantavirus Outbreak on a Cruise Ship, 2026 (NEJM) “Super-Spreaders” and Person-to-Person Transmission of Andes Virus in Argentina (NEJM) Person-to-Person Transmission of Andes Virus in Hantavirus Pulmonary Syndrome, Argentina, 2014 (CDC: Emerging Infectious Diseases) Hantavirus on board with Prof. VincentRacaniello (microbeTV) Ebola dashboard (ebola.fyi) Epidemic of Ebola Disease caused by Bundibugyo virus in the Democratic Republic of the Congo and Uganda determined a public health emergency of international concern (WHO) WHO ramps up support to the Democratic Republic of the Congo’s Ebola outbreak response (WHO: Democratic Republic of Congo) WHO chief says fast-moving Ebola epidemic is outpacing response efforts (Reuters) US CDC seeks staff for Ebola screening as outbreak response expands (Reuters) Trump Administration to Send Americans Exposed to Ebola to Kenya (NY Times) Single Immunization With a Monovalent Vesicular Stomatitis Virus–Based Vaccine Protects Nonhuman Primates Against Heterologous Challenge With Bundibugyo ebolavirus (JID) Vesicular Stomatitis Virus-Based Vaccines Protect Nonhuman Primates against Bundibugyo ebolavirus (PLoS Neglected Tropical Diseases) Vaccine experts debate options to combat outbreak of unusual Ebola strain (Science) NIAID Establishes Centers for Research in Emerging Infectious Diseases (NIAID.NIH) Inside the Race to Develop a Test for the Rare Andes Hantavirus (Wired) NIH terminates network aimed at stopping pandemics before they start (Science) These Researchers Would Be in Africa Fighting Ebola—but Trump Cut Their Funding (Wired) Wastewater for measles (WasterWater Scan) Measles cases and outbreaks (CDC Rubeola) Big outbreak, bright lights…Measles Dashboard(South Carolina Department of Public Health) Utah measles outbreak response (Utah Department of Health and Human Services) Utah Measles Dashboard (Utah Department of Health and Human Services) Tracking Measles Cases in the U.S. (Johns Hopkins) Measles vaccine recommendations from NYP (jpg) Weekly measles and rubella monitoring (Government of Canada) Measles (WHO) Get the FACTS about measles (NY State Department of Health) Measles (CDC Measles (Rubeola)) Measles vaccine (CDC Measles (Rubeola)) Presumptive evidence of measles immunity (CDC) Contraindications and precautions to measles vaccination (CDC) Adverse events associated with childhood vaccines: evidence bearing on causality (NLM) Measles Vaccination: Know the Facts (ISDA: Infectious Diseases Society of America) Deaths following vaccination: what does the evidence show (Vaccine) Characteristics of Patients Hospitalized with Measles During an Outbreak — West Texas, <a href= "https://www.cdc.gov/mmwr/volumes/75/wr/mm7520a1.htm?s_cid=OS_mm7...
Transcribe →TWiV 1325: Sticky flu with Hannah Rowe
May 2400:57:06Tap to summarizeVincent travels to Oregon State University in Corvallis to meet up with Hannah Rowe to talk about her career and her work demonstrating how the interaction of influenza A virus and Streptococcus pneumonia influences transmission. Hosts: Vincent Racaniello Guest: Hannah Rowe Subscribe (free): Apple Podcasts, RSS, email Become a patron of TWiV! Links for this episode Support science education at MicrobeTV Positions in Rosenfeld Lab (email) Respiratory bacteria stabilize influenza A virus (mSystems) S. pneumoniae and influenza A virus binding (mSphere) Bacterial alteration of redox stressors and stability of influenza A virus (mSphere) Timestamps by Jolene Ramsey. Thanks! Intro music is by Ronald Jenkees Send your virology questions and comments to twiv@microbe.tv Content in this podcast should not be construed as medical advice.
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