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At Euroanaesthesia in Rotterdam, TopMedTalk hosts Andy Cumpstey and Kate Leslie speak with Joana Berger-Estilita, ESAIC chair of education and training, about ESAIC's new leadership program. Developed over two years with a multidisciplinary team including ESAIC leadership and headquarters staff, the pilot addresses a gap for seasoned anaesthesiologists seeking further career progression. The retreat-style, experiential course includes two extended weekends (December and March), selects 25 ESAIC members with at least five years post-training leadership experience, and pairs participants with mentors. Content covers core leadership skills plus anaesthesia-specific challenges such as second victim, suicide, and drug abuse, alongside self-care. Funding is shared by industry and ESAIC, with applications via the ESAIC website. -- Join us at Evidence Based Perioperative Medicine (EBPOM) World Congress 2026 in London. Be part of a global conversation as clinicians from around the world gather between 7-9th July at the British Library in London. Three days of evidence-based perioperative medicine, global insights, and expert debate—featuring speakers including Michael Marmot and Ken Rockwood. Register here - https://ebpom.org/product/ebpom-world-congress-2026/

At the World Congress of Anaesthesiologists (WCA) in Marrakech, Morocco, TopMedTalk co-editors In chief, Kate Leslie and Mike Grocott speak with Sydney anaesthesiologist Alwin Chuan, a member of the joint ESRA-ASRA working group on AI, about strengths and limitations of AI for regional anaesthesia and medicine. Chuan explains how generative AI is trained on vast datasets using transformer architectures, why outputs are probabilistic, and how context affects meaning. They discuss privacy and the possibility of personal or creative work being used as a commodity in training, internet "scraping," and the inevitability of hallucinations, including false facts and fabricated citations. The conversation covers bias in training corpora, the need for human curation and reinforcement learning, and mitigation via prompt engineering such as retrieval-augmented generation (RAG), citation/page verification, and confidence estimates. Chuan predicts future advances and the fusion of imaging AI with generative AI for ultrasound guidance, previewing a follow-up episode. -- Join us at Evidence Based Perioperative Medicine (EBPOM) World Congress 2026 in London. Be part of a global conversation as clinicians from around the world gather between 7-9th July at the British Library in London. Three days of evidence-based perioperative medicine, global insights, and expert debate—featuring speakers including Michael Marmot and Ken Rockwood. Register here - EBPOM World Congress 2026

At Euroanaesthesia in Rotterdam, TopMedTalk hosts Andy Cumpsty and Kate Leslie speak with Denise Veelo Professor of Anesthesiology at the Amsterdam University Medical Center and Bernd Saugel Professor of Anesthesiology and Vice Chair of the Department of Anesthesiology in the Center of Anesthesiology and Intensive Care Medicine at the University Medical Center Hamburg-Eppendorf, about two JAMA blood-pressure trials published on the same day. Veelo describes a 3,500-patient, two-center randomized trial comparing usual care (MAP 65) with more intensive, risk-stratified higher MAP thresholds (70/80/90) using a functional recovery primary outcome, stopped early for futility. Saugel outlines the 1,300-patient IMPROVE trial in 15 German centers, individualizing the lower intervention threshold to each patient's preoperative nighttime MAP versus routine MAP 65, with a 7-day composite outcome; no significant difference was found and event rates were ~30%. They conclude routine targeting substantially above MAP 65 is not supported for broad populations, note special circumstances may differ, and they discuss limitations, vasopressor-heavy practice, and future research including the ASPIRE 85 delirium-focused trial and work on autoregulation and physiology. -- The 2026 International Practicum on Cardiopulmonary Exercise Testing will be held at the Balmer Lawn Hotel in Brockenhurst, UK, from September 16th to 18th this year. It is organised by iPOETTS , the international perioperative testing and training society. Come and join us at this premier educational event designed for clinicians, scientists, and healthcare professionals interested in sport, exercise, and perioperative medicine. This is an International Perioperative Testing and Training Society accredited event so when you attend you can get your iPOETTS accreditation, showing that you are a practitioner who has reached a high, standardized level of competence in performing and interpreting Cardiopulmonary Exercise Testing (CPET) for patients preparing for major surgery. Go now to http://www.ebpom.org

At this year's Euroanaesthesia meeting in Rotterdam, TopMedTalk host Andy Cumpsty interviews Wolfgang Buhre, Professor of Anesthesia and Perioperative Medicine at Utrecht University Medical Center and past president of the European Society of Anaesthesiology and Intensive Care (ESAIC). The discussion starts with a focus upon the annual ESAIC congress and its international reach, with next year's meeting planned for Copenhagen. Buhre explains ESAIC's White Paper, developed over two years using interviews and desk research with clinicians, stakeholders, and patient perspectives, to clarify the role of anesthesiologists and communicate core values and strategic goals for 2026. Key priorities include addressing workforce shortages and Europe-wide variation in training and working conditions, protecting patient safety, ensuring availability of critical medicines and supplies, and expanding standardized education tools such as the European Diploma. He outlines next steps focused on advocacy with European institutions and support for national societies. -- The 2026 International Practicum on Cardiopulmonary Exercise Testing will be held at the Balmer Lawn Hotel in Brockenhurst, UK, from September 16th to 18th this year. It is organised by iPOETTS , the international perioperative testing and training society. Come and join us at this premier educational event designed for clinicians, scientists, and healthcare professionals interested in sport, exercise, and perioperative medicine. This is an International Perioperative Testing and Training Society accredited event so when you attend you can get your iPOETTS accreditation, showing that you are a practitioner who has reached a high, standardized level of competence in performing and interpreting Cardiopulmonary Exercise Testing (CPET) for patients preparing for major surgery. Go now to http://www.ebpom.org

Andy Cumpstey and Mike Grocott interview Kate Leslie about the SNaPP study (Sugammadex, Neostigmine, and Postoperative Pulmonary Complications). SNaPP is a pragmatic randomized study run from the University of Melbourne with the ANZCA Clinical Trials Network across 45 sites in Australia, New Zealand, and Hong Kong. Patients aged 40+ having major abdominal or thoracic surgery (≥2 hours, overnight stay) were randomized after induction to reversal with sugammadex or neostigmine, with anesthetists unblinded and encouraged to use quantitative neuromuscular monitoring. In this podcast Andy, Mike and Kate discuss the results and their implications for anaesthetists and healthcare systems. Find the paper here: https://www.thelancet.com/journals/lanres/article/PIIS2213-2600(26)00158-X/fulltext -- Join us at Evidence Based Perioperative Medicine (EBPOM) World Congress 2026 in London. Be part of a global conversation as clinicians from around the world gather between 7-9th July at the British Library in London. Three days of evidence-based perioperative medicine, global insights, and expert debate—featuring speakers including Michael Marmot and Ken Rockwood. Register here - https://ebpom.org/product/ebpom-world-congress-2026/

At the Annual Scientific Meeting of the Australian and New Zealand College of Anaesthetists (ANZCA) and Faculty of Pain Medicine (FPM) held in Auckland, New Zealand, Kate Leslie and Andy Cumpstey interview the annual scientific meeting convenor Kerry Benson-Cooper and conference cultural advisor Tui Blair about planning the meeting and how Māori traditions and culture have informed not only the conference but also patient care and education in New Zealand. Dr Kerry Benson-Cooper is a specialist anaesthetist and intensive care physician at Te Toka Tumai Auckland Hospital, New Zealand. Tui Blair is interim co director of patient services, Health New Zealand | Te Toka Tumai Auckland, New Zealand.

At the SOAP meeting in Montreal, Desiree Chappell and Monty Mythen interview Dr. Marie Louise Meng, Assistant Professor of Anesthesiology at Duke University Department of Anesthesiology and her former cardio-obstetric fellow Liliane Ernst, assistant professor in the Obstetric and Gynecologic Anesthesia section Wake Forest University. The conversation focuses on cardio-obstetric anesthesia, hemodynamics, monitoring, and patient-centered care. Meng describes building multidisciplinary "pregnancy heart teams" to plan management for complex cardiac disease in pregnancy and reduce birth trauma. Ernst discusses research using the Premier database on preexisting atrial fibrillation in pregnancy (about 25 per 100,000 deliveries) and associated management and outcomes. They review cases including mechanical circulatory support with an Impella to prolong pregnancy and highlight knowledge gaps about placental perfusion and pulsatility, including Fontan physiology. Meng outlines individualized hemodynamic monitoring for labor and C-sections, emphasizes recognizing hypertensive instability, and details preeclampsia with severe features, its end-organ criteria, incidence, disparities, postpartum follow-up challenges, and potential use of remote monitoring and noninvasive cardiac output/SVR monitoring to guide therapy. Monty Mythen, founding editor-in-chief of TopMedTalk, is now Senior Vice President, Scientific Liaison, BD Advanced Patient Monitoring. He is also Emeritus Professor of Anaesthesia and Critical Care, University College London, UK. Desirée Chappell, former co-editor-in-chief of TopMedTalk, is now Director of Medical Affairs and Medical Science Liaison, BD Advanced Patient Monitoring. She is also a CRNA at NorthStar Anesthesia, USA. -- Join us at Evidence Based Perioperative Medicine (EBPOM) World Congress 2026 in London. Be part of a global conversation as clinicians from around the world gather between 7-9th July at the British Library in London. Three days of evidence-based perioperative medicine, global insights, and expert debate—featuring speakers including Michael Marmot and Ken Rockwood. Register here - EBPOM World Congress 2026

TopMedTalk introduces our new "TopMedTalk Classics" series with a classic TopMedTalk episode from 2018 that is still prescient today. This lecture, given by Sir Bruce Keogh marked the NHS's 70th birthday, a time framed by political volatility, financial constraint, rising demand, and shifting public expectations. Keogh argues healthcare systems must adapt, highlighting the UK's strengths in medical science, innovation, life sciences, and the scale and complexity of the NHS. He describes quality improvement efforts since 2008, including defining quality as effectiveness, safety, and patient experience, developing outcomes measures, and using aligned clinical and managerial leadership to drive change. Examples include major reductions in MRSA, rapid increases in VTE assessment, improved survival from major trauma networks, better hip-fracture care, strong heart-attack and sepsis performance, stroke centralization benefits, and increased dementia diagnosis for support. He emphasizes future pressures from ageing, prevention, the health–social care split, Brexit workforce and drug costs, and emerging forces like mobile tech, AI, genomics, and gene therapy, arguing the NHS's pooled, universal model is well suited to a genomics-enabled future. -- Join us at Evidence Based Perioperative Medicine (EBPOM) World Congress 2026 in London. Be part of a global conversation as clinicians from around the world gather between 7-9th July at the British Library in London. Three days of evidence-based perioperative medicine, global insights, and expert debate—featuring speakers including Michael Marmot and Ken Rockwood. Register here - https://ebpom.org/product/ebpom-world-congress-2026/ 00:00 TopMed Talk Intro 00:18 Classics Episode Setup 01:31 Introducing Sir Bruce 02:23 Politics And Adaptation 04:41 Global Pressures On Healthcare 05:48 Hard Times Build NHS 07:35 UK Innovation Advantage 10:33 NHS Scale And Complexity 12:27 Darzi Review Quality Drive 16:10 Outcomes Framework Explained 17:20 Safety And High Level Metrics 18:09 MRSA Turnaround Lesson 20:11 Mandating VTE Prevention 22:58 Trauma Networks Results 24:08 Hip Fracture Best Practice 25:21 Heart Attack Care Wins 26:17 Sepsis And Early Warning 28:01 Stroke Centralization Success 28:45 Dementia Targets Debate 30:31 Leadership And Brexit Risks 32:35 Health And Social Care Split 36:01 Tech Disruption Ahead 36:49 Genomics And NHS Values 38:00 Closing And Congress Promo

The Association of Anaesthetists meeting in London was the perfect spot for us to launch our new series on Artificial Intelligence. Here, Andy Cumpstey and James Bowness discuss the new monthly series and the UK-Ireland "demand signaling" project on AI in anaesthesia, perioperative medicine and acute pain, supported by The Association. They are joined by their guest Nicky De Beer, The Association's chief executive. She explains that their members want problems defined in advance before technology solutions are imposed from above. She highlights key clinical themes—enhanced monitoring and decision support, personalized anaesthesia, and automation of routine tasks—and nonclinical impacts such as operational efficiency and data-driven decision making. The conversation stresses embracing AI with caution, addressing basic IT shortcomings, developing CPD/training, multidisciplinary research, ethical and safety-focused policy, international collaboration, grant funding, and progressing toward practical AI guidelines and advocacy with policymakers. -- Join us at Evidence Based Perioperative Medicine (EBPOM) World Congress 2026 in London. Be part of a global conversation as clinicians from around the world gather between 7-9th July at the British Library in London. Three days of evidence-based perioperative medicine, global insights, and expert debate—featuring speakers including Michael Marmot and Ken Rockwood. Register here - https://ebpom.org/product/ebpom-world-congress-2026/

Settle yourself in for another fascinating glimpse behind the curtain as TopMedTalk's perioperative profiles focus upon the incredible journey of Vanessa Beavis. Recorded at ANZCA's recent annual scientific meeting in Auckland, TopMedTalk host Andy Cumpsty interviews anesthetist and former ANZCA President Vanessa Beavis about her path from growing up in South Africa to moving to Auckland in 1993. We discuss her early work in obstetrics, solo general practice, and training in anesthesia before emigrating. She describes becoming involved in departmental leadership, navigating hospital governance to implement safety changes, and progressing through examiner roles, national committees, council, and ultimately ANZCA presidency. A role which coincided with COVID-19, when the College focused on maintaining robust training and examinations and producing clear PPE and clinical guidance across changing state rules. She also recounts helping develop ANZCA's perioperative medicine work from the 2004 task force to the SIG, qualifications, the Australian New Zealand Perioperative Patient Pathway, and the new chapter, and reflects on receiving the Companion of the New Zealand Order of Merit. -- Previous Perioperative Profiles you may also enjoy: https://topmedtalk.libsyn.com/perioperative-profiles-denny-levett https://topmedtalk.libsyn.com/perioperative-profile-rupert-pearse https://topmedtalk.libsyn.com/perioperative-profiles-professor-michelle-chew-on-seizing-opportunities-in-anaesthesia-research-editing-and-guideline-work Also, remember you can join us at Evidence Based Perioperative Medicine (EBPOM) World Congress 2026 in London. Be part of a global conversation as clinicians from around the world gather between 7-9th July at the British Library in London. Three days of evidence-based perioperative medicine, global insights, and expert debate—featuring speakers including Michael Marmot and Ken Rockwood. Register here - https://ebpom.org/product/ebpom-world-congress-2026/