Stress feels louder, sleep feels harder, and your nervous system is fried. Welcome to midlife! In this episode, Joe Sheehey, founder of Cured Nutrition, breaks down the endocannabinoid system, how it impacts stress and sleep, and why it matters even more for women 35+. We also dive into exactly how to tinker with CBD, CBN, and microdosing THC in a practical, science-based way. No hype or overselling, just tools you can use in everyday life

Timestamps:

[1:38] Intro

[6:15] Welcome Joe - can you break down the differences between CBD, CBN, and THC in practical terms?

[11:20] Tell me more about the cannabinoid system and how supplementation actually works.

[14:58] Is there any literature that shows that people become deficient in cannabinoids?

[15:50] Talk to me about CBN

[20:57] Is there a difference the way men respond vs women?

[22:49] If somebody sees the product and it has THC in it, talk to me about the dosing. What is a microdose? What do you see to be most effective?

[28:27] For women who are 35 years old, where does THC shine? Is it more about the relaxation or in how you deal with your daily stress? Are we taking it every day? Do you become dependent on it? Talk to me about it.

[33:44] What are the biggest mistakes people make when trying to teach or even micro using it for the first time?

[36:11] If somebody is really struggling with their sleep, would you recommend they just try CBD or just try CBN or do you think they should try a combination of everything?

[39:55] How does CBN differ from melatonin or magnesium?

[43:50] Do you find that people who practice healthier lifestyles that cannabinoids work more effectively and they need less of it?

[58:19] What would you say to the person who said CBD or CBN did not work for me?

[1:05:14] For the salve, how does it work to target the pain?

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The Journal of Neuropsychopharmacology Article

Article Summary:
The study you are likely referring to is a 2021 clinical trial conducted by researchers at Johns Hopkins Medicine, published in the journal Neuropsychopharmacology.
This study is significant because it identified a "sweet spot" dose for THC (specifically 2.5 mg) that could provide therapeutic benefits (pain relief) without the negative intoxicating effects or "high" associated with larger doses.

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